Education
Academic Background-
Ph.D. Westfalisch Wilhems University, Germany Biochemistry | Completed: 2001
Publications (126)
Selected Scholarly Contributions
Fish oil supplementation reduces the CERT2 risk score in adults with increased cardiometabolic risk: findings from the MoKaRi trial
2026
Evaluation of School Lunch Quality in Accordance with the Quality Standard for Meals in Schools of the German Nutrition Society in a Selection of Thuringian Schools
2026
The Vitamin E Derivative Garcinoic Acid Suppresses NLRP3 Inflammasome Activation and Pyroptosis in Murine Macrophages
2025
Reduction of cardiovascular risk factors by the diet – Evaluation of the MoKaRi concept by a parallel-designed randomized study
2025
Protein intake and cardiovascular diseases: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society
2025
Optimized assay for the measurement of caspase‐1 expression, release, and activity in murine macrophages
2024
Protein intake and type 2 diabetes mellitus: an umbrella review of systematic reviews for the evidence-based guideline for protein intake of the German Nutrition Society
2024
Protein intake and body weight, fat mass and waist circumference: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society
2024
Chemopreventive effects of α-tocopherol and its long-chain metabolites α-13′-hydroxy- and α-13′-carboxychromanol in LT97 colon adenoma cells
2024
Dietary protein and blood pressure: an umbrella review of systematic reviews and evaluation of the evidence
2024
Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes—The MoKaRi II Randomized Controlled Study
2024
Changing impact of dietary risk factors on cardiovascular mortality in 46 European countries from 1990 to 2019 by age and sex: A data article of the GBD Study
2024
α‐Tocopherol Long‐Chain Metabolite α‐T‐13′‐COOH Exhibits Biphasic Effects on Cell Viability, Induces ROS‐Dependent DNA Damage, and Modulates Redox Status in Murine RAW264.7 Macrophages
2024
Effects of Histamine and the α-Tocopherol Metabolite α-13′-COOH in an Atopic Dermatitis Full-Thickness Skin Model
2023
Phytosterols and Cardiovascular Risk Evaluated against the Background of Phytosterolemia Cases—A German Expert Panel Statement
2023
Impact of Regular Intake of Microalgae on Nutrient Supply and Cardiovascular Risk Factors: Results from the NovAL Intervention Study
2023
Protein intake and bone health: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society
2023
Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society
2023
α-Tocopherol-13′-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation
2023
2023
Establishment and Characterization of Mild Atopic Dermatitis in the DNCB-Induced Mouse Model
2023
Evaluation of Influencing Factors on Metabolism of Land-Based n-3 Poly Unsaturated Fatty Acids—The KoALA Study
2023
Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci
2022
The α-tocopherol-derived long-chain metabolite α-13′-COOH mediates endotoxin tolerance and modulates the inflammatory response via MAPK and NFκB pathways
2022
Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society
2022
Gender- and subgroup-specific sensitivity analysis of alcohol consumption and mortality in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study
2022
Use of the β-Glucan-Producing Lactic Acid Bacteria Strains Levilactobacillus brevis and Pediococcus claussenii for Sourdough Fermentation—Chemical Characterization and Chemopreventive Potential of In Situ-Enriched Wheat and Rye Sourdoughs and Breads
2022
Genetics and Epigenetics in Personalized Nutrition: Evidence, Expectations, and Experiences
2022
Vitamin E and Metabolic Health: Relevance of Interactions with Other Micronutrients
2022
Nutritional Assessment of Ready-to-Eat Salads in German Supermarkets: Comparison of the nutriRECIPE-Index and the Nutri-Score
2022
Chemopreventive effects of raw and roasted oat flakes after in vitro fermentation with human faecal microbiota
2021
2021
Thermal Processing has no Impact on Chemopreventive Effects of Oat and Barley Kernels in LT97 Colon Adenoma Cells
2021
Fermentation profile, cholesterol-reducing properties and chemopreventive potential of β-glucans from Levilactobacillus brevis and Pediococcus claussenii – a comparative study with β-glucans from different sources
2021
Variability in Macro- and Micronutrients of 15 Commercially Available Microalgae Powders
2021
A study protocol of a randomized trial evaluating the effect of using defined menu plans within an intensive personal nutritional counseling program on cardiovascular risk factors: The MoKaRi (modulation of cardiovascular risk factors) trial
2021
Controlled Release of the α-Tocopherol-Derived Metabolite α-13′-Carboxychromanol from Bacterial Nanocellulose Wound Cover Improves Wound Healing
2021
Alcohol consumption and mortality: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study
2021
Meta-analyses identify DNA methylation associated with kidney function and damage
2021
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus
2021
Olive Oil Extracts and Oleic Acid Attenuate the LPS-Induced Inflammatory Response in Murine RAW264.7 Macrophages but Induce the Release of Prostaglandin E2
2021
Study on chemopreventive effects of raw and roasted β-glucan-rich waxy winter barley using an in vitro human colon digestion model
2020
2020
The Peroxisome Proliferator–Activated Receptor (PPAR)-γ Antagonist 2-Chloro-5-Nitro-N-Phenylbenzamide (GW9662) Triggers Perilipin 2 Expression via PPARδ and Induces Lipogenesis and Triglyceride Accumulation in Human THP-1 Macrophages
2020
Functional Biomarkers for the Selenium Status in a Human Nutritional Intervention Study
2020
Process control and scale-up of modified bacterial cellulose production for tailor-made anti-inflammatory drug delivery systems
2020
Cardiovascular and Metabolic Protection by Vitamin E: A Matter of Treatment Strategy?
2020
Changes in Erythrocyte Omega-3 Fatty Acids in German Employees upon Dietary Advice by Corporate Health
2020
2020
2020
2019
Impact of different roasting conditions on chemical composition, sensory quality and physicochemical properties of waxy-barley products
2019
In Vitro Digested Nut Oils Attenuate the Lipopolysaccharide-Induced Inflammatory Response in Macrophages
2019
Patterns of Biodynamic Milk Fatty Acid Composition Explained by A Climate-Geographical Approach
2019
Metabolic footprint and intestinal microbial changes in response to dietary proteins in a pig model
2019
An App to Improve Eating Habits of Adolescents and Young Adults (Challenge to Go): Systematic Development of a Theory-Based and Target Group–Adapted Mobile App Intervention
2019
Influence of roasting on the chemopreventive potential of in vitro fermented almonds in LT97 colon adenoma cells
2018
Natural 6-hydroxy-chromanols and -chromenols: structural diversity, biosynthetic pathways and health implications
2018
Long-Chain Metabolites of Vitamin E: Metabolic Activation as a General Concept for Lipid-Soluble Vitamins?
2018
Optimized incubation regime for nitric oxide measurements in murine macrophages using the Griess assay
2017
Chemopreventive Potential of Raw and Roasted Pistachios Regarding Colon Carcinogenesis
2017
2016
Recruitment of CD16 + monocytes to endothelial cells in response to LPS-treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine
2016
Omega-3 fatty acids and mortality in patients referred for coronary angiography. The Ludwigshafen Risk and Cardiovascular Health Study
2016
A procedure for efficient non-viral siRNA transfection of primary human monocytes using nucleofection
2015
Human serum determination and in vitro anti-inflammatory activity of the vitamin E metabolite α-(13'-hydroxy)-6-hydroxychroman
2015
Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells
2014
Complexity of fatty acid distribution inside human macrophages on single cell level using Raman micro-spectroscopy.
Stefan Lorkowski
2014
Association of dietary, circulating and supplement fatty acids with coronary risk.
Stefan Lorkowski
2014
Regulatory metabolites of vitamin E and their putative relevance for atherogenesis.
Stefan Lorkowski
2014
Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro.
Stefan Lorkowski
2014
Reduced PMA enhances the responsiveness of transfected THP-1 macrophages to polarizing stimuli.
Stefan Lorkowski
2014
Relationships between cargo, cell penetrating peptides and cell type for uptake of non-covalent complexes into live cells.
Stefan Lorkowski
2013
Chemical and enzymatic characterization of recombinant rabbit muscle pyruvate kinase.
Stefan Lorkowski
2013
Transduction of proteins into Leishmania tarentolae by formation of non-covalent complexes with cell-penetrating peptides.
Stefan Lorkowski
2013
Evidence for an alternative genomic structure, mRNA and protein sequence of human ABCA13.
Stefan Lorkowski
2013
Noninvasive imaging of intracellular lipid metabolism in macrophages by Raman microscopy in combination with stable isotopic labeling.
Stefan Lorkowski
2012
Laminin isoforms in atherosclerotic arteries from mice and man.
Stefan Lorkowski
2011
RASL11B (RAS-like, family 11, member B).
Stefan Lorkowski
2010
Chemistry meets nutrition: Toward a systems biological description of human metabolism.
Stefan Lorkowski
2010
TIP47, a lipid cargo protein involved in macrophage triglyceride metabolism.
Stefan Lorkowski
2009
2009
GFP-tagged proteins visualized by freeze-fracture immuno-electron microscopy: A new tool in cellular and molecular medicine.
Stefan Lorkowski
2009
Collagen-bound LDL modifies endothelial cell adhesion to type V.
Stefan Lorkowski
2009
Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.
Stefan Lorkowski
2009
2008
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked, SNPs in the ANRIL locus on chromosome 9p.
Stefan Lorkowski
2008
Production of type VI collagen by human macrophages: A new dimension in macrophage functional heterogeneity.
Stefan Lorkowski
2008
Exogenous nitric oxide regulates activity and synthesis of vascular endothelial nitric oxide synthase.
Stefan Lorkowski
2008
HDL-associated lysosphingolipids Inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production.
Stefan Lorkowski
2008
Expression of perilipin isoforms in cell types involved in atherogenesis.
Stefan Lorkowski
2007
Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsible element.
Stefan Lorkowski
2007
Cloning, genomic organization and tissue-specific expression of the RASL11B gene.
Stefan Lorkowski
2007
2006
Cell surface localization of ABCG1 does not require LXR activation.
Stefan Lorkowski
2006
TGF-β1 generates a specific multicomponent extracellular matrix in human coronary SMC.
Stefan Lorkowski
2006
Spatial integration of TIP47 and adipophilin in macrophage lipid bodies.
Stefan Lorkowski
2005
Pharmacological regulation of cholesterol efflux in human monocyte-derived macrophages in the absence of exogenous cholesterol acceptors.
Stefan Lorkowski
2005
Lipid droplets gain PAT family proteins by interaction with specialized plasma membrane domains.
Stefan Lorkowski
2005
Cloning, cellular localization, genomic organization and tissue-specific expression of the TGFβ1-inducible SMAP-5 gene.
Stefan Lorkowski
2005
Correspondence of function and phylogeny of ABC proteins based on an automated analysis of 20 model protein data sets.
Stefan Lorkowski
2005
High-density lipoprotein cholesterol levels and cholesterol efflux: A missing link?
Stefan Lorkowski
2004
The ABC of cholesterol efflux and high-density lipoprotein formation.
Stefan Lorkowski
2004
High-throughput analysis of mRNA expression: Microarrays are not the whole story.
Stefan Lorkowski
2004
VisCoSe: Visualization and comparison of consensus sequences.
Stefan Lorkowski
2004
ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export.
Stefan Lorkowski
2004
Cholesterol absorption inhibitor ezetimibe blocks uptake of oxidized LDL in human macrophages.
Stefan Lorkowski
2004
Characterization of the synthetic compatible solute homoectoine as a potent PCR enhancer.
Stefan Lorkowski
2004
Proinflammatory cytokines regulate LOX-1 expression in vascular smooth muscle cells.
Stefan Lorkowski
2004
Laser microdissection-based analysis of mRNA expression in human coronary arteries with intimal thickening.
Stefan Lorkowski
2004
Inflammation in atherosclerosis, not yet time for a paradigm shift?
Stefan Lorkowski
2003
Learning new tricks from an old dog: Recent findings in familial hypercholesterolemia.
Stefan Lorkowski
2003
Rupture of the atherosclerotic plaque does a good animal model exist?
Stefan Lorkowski
2003
Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-binding cassette transporter A1.
Stefan Lorkowski
2003
BLASTing proteomes, yielding phylogenies.
Stefan Lorkowski
2003
Genetics and molecular biology: Peroxisome proliferator-activated receptor [gamma] still full of surprises.
Stefan Lorkowski
2002
Genetics and molecular biology: Apolipoprotein E-from plasma lipids to plaque stability.
Stefan Lorkowski
2002
Macrophage function and stability of the atherosclerotic plaque: Progress report of a European project.
Stefan Lorkowski
2002
DNA microarrays in medicine: Manufacturing techniques and potential applications.
Stefan Lorkowski
2002
2002
Genomic sequence and structure of the human ABCG1 (ABC8) gene.
Stefan Lorkowski
2001
Apolipoprotein E in macrophages and hepatocytes is degraded via the proteasomal pathway.
Stefan Lorkowski
2001
Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease.
Stefan Lorkowski
2001
ATP binding cassette transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte-derived macrophages.
Stefan Lorkowski
2001
The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages.
Stefan Lorkowski
2001
Use of longer extension phases to improve yield of high molecular weight products in differential display PCR.
Stefan Lorkowski
2000