Dr. Kamaleldin Hany Hussein
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Dr. Kamaleldin Hany Hussein

Postdoctoral Researcher
Center of Biological Engineering, Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Leicestershire, United Kingdom

Highest Degree
Ph.D. in Clinical Veterinary Medicine from Kangwon National University, Korea

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Biography

Dr. Kamal Hussein obtained his Ph.D. in clinical veterinary medicine at Kangwon National University, South Korea in Feb, 2016. His PhD work entitled “Development of a bioengineered transplantable liver graft with re-endothelialized vasculature for generating humanized organ”. He has been focusing on decellularization of rat and porcine liver, followed by recellularization with human hepatocytes and endothelial cells for engineering organ mimics human liver microenvironment.

Area of Interest:

Biomedical Sciences
100%
Biological Engineering
62%
Veterinary Medicine
90%
Tissue Engineering
75%
Biomaterials
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
49
Abstracts
10

Selected Publications

  1. Soliman, M., A.A. Sadek, H.N. Abdelhamid and K. Hussein, 2021. Graphene oxide-cellulose nanocomposite accelerates skin wound healing. Res. Vet. Sci., 137: 262-273.
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  2. Mousa, H.M., K.H. Hussein, M.M. Sayed, M.K.A. El-Rahman and H.M. Woo, 2021. Development and characterization of cellulose/iron acetate nanofibers for bone tissue engineering applications. Polymers, Vol. 13. 10.3390/polym13081339.
    CrossRef  |  Direct Link  |  
  3. Fang, S., A.H. Ahlmann, L. Langhorn, K. Hussein and J.A. Sørensen et al., 2021. Small diameter polycaprolactone vascular grafts are patent in sheep carotid bypass but require antithrombotic therapy. Regener. Med., 16: 117-130.
    CrossRef  |  Direct Link  |  
  4. Abdelhamid, H.N. and K.H. Hussein, 2021. Graphene oxide as a carrier for drug delivery of methotrexate. Biointerface Res. Appl. Chem., 11: 14726-14735.
    CrossRef  |  Direct Link  |  
  5. Park, S.Y., J.H. An, H. Kwon, S.Y. Choi and K.Y. Lim et al., 2020. Custom-made artificial eyes using 3D printing for dogs: A preliminary study. PLoS ONE, Vol. 15. 10.1371/journal.pone.0242274.
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  6. Mousa, H.M., K.H. Hussein, M.M. Sayed, M.R. El-Aassar and I.M.A. Mohamed et al., 2020. Development of biocompatible tri-layered nanofibers patches with endothelial cells for cardiac tissue engineering. Eur. Polym. J., Vol. 129. 10.1016/j.eurpolymj.2020.109630.
    CrossRef  |  Direct Link  |  
  7. Kwak, H.H., K.H. Hussein, H.M. Woo and K.M. Park, 2020. Emphysematous pyelonephritis associated with calcium oxalate uroliths detected on computed tomography in an awake dog. Korean J. Vet. Res., 60: 93-96.
    CrossRef  |  Direct Link  |  
  8. Hussein, K.H., K.M. Park, L. Yu, S.H. Song, H.M. Woo and H.H. Kwak, 2020. Vascular reconstruction: A major challenge in developing a functional whole solid organ graft from decellularized organs. Acta Biomater., 103: 68-80.
    CrossRef  |  Direct Link  |  
  9. Hussein, K.H., K.M. Park, L. Yu, H.H. Kwak and H.M. Woo, 2020. Decellularized hepatic extracellular matrix hydrogel attenuates hepatic stellate cell activation and liver fibrosis. Mater. Sci. Eng.: C, Vol. 116. 10.1016/j.msec.2020.111160.
    CrossRef  |  Direct Link  |  
  10. Fang, S., S.S. Riber, K. Hussein, A.H. Ahlmann and E.B. Harvald et al., 2020. Decellularized human umbilical artery: Biocompatibility and in vivo functionality in sheep carotid bypass model. Mater. Sci. Eng.: C, Vol. 112. 10.1016/j.msec.2020.110955.
    CrossRef  |  Direct Link  |  
  11. Ali, M.M., K.H. Hussein, A. Sadek and A.E. Abdelbaset, 2020. Congenital urethral dilatation in cattle calves: Diagnosis and surgical intervention. Vet. World, 13: 261-265.
    CrossRef  |  Direct Link  |  
  12. Hussein, K.H., H.N. Abdelhamid, X. Zou and H.M. Woo, 2019. Ultrasonicated graphene oxide enhances bone and skin wound regeneration. Mater. Sci. Eng.: C, 94: 484-492.
    CrossRef  |  Direct Link  |  
  13. Saleh, T.M., E.A. Ahmed, L. Yu, H.H. Kwak and K.H. Hussein et al., 2018. Incorporation of nanoparticles into transplantable decellularized matrices: Applications and challenges. Int. J. Artif. Organs, 41: 421-430.
    CrossRef  |  Direct Link  |  
  14. Saleh, T., E. Ahmed, L. Yu, K. Hussein and K.M. Park et al., 2018. Silver nanoparticles improve structural stability and biocompatibility of decellularized porcine liver. Artif. Cells Nanomed. Biotechnol., 46: 273-284.
    CrossRef  |  Direct Link  |  
  15. Hussein, K.H., T. Saleh, E. Ahmed, H.H. Kwak and K.M. Park et al., 2018. Biocompatibility and hemocompatibility of efficiently decellularized whole porcine kidney for tissue engineering. J. Biomed. Mater. Res., 106: 2034-2047.
    CrossRef  |  Direct Link  |  
  16. Ingole, V.H., K.H. Hussein, A.A. Kashale, K. Ghule and T. Vuherer et al., 2017. Ultrasound-assisted green economic synthesis of hydroxyapatite nanoparticles using eggshell biowaste and study of mechanical and biological properties for orthopedic applications. J. Biomed. Mater. Res., 105: 2935-2947.
    CrossRef  |  Direct Link  |  
  17. Hussein, K.H., K.M. Park, Y.S. Lee, J.S. Woo and B.J. Kang et al., 2017. New insights into the pros and cons of cross-linking decellularized bioartificial organs. Int. J. Artif. Organs, 40: 136-141.
    CrossRef  |  Direct Link  |  
  18. Abdal-Hay, A., A. Memic, K.H. Hussein, Y.S. Oh and M. Fouad et al., 2017. Rapid fabrication of highly porous and biocompatible composite textile tubular scaffold for vascular tissue engineering. Eur. Polym. J., 96: 27-43.
    CrossRef  |  Direct Link  |  
  19. Park, K.M., K.H. Hussein, S.H. Hong, C. Ahn and S.R. Yang et al., 2016. Decellularized liver extracellular matrix as promising tools for transplantable bioengineered liver promotes hepatic lineage commitments of induced pluripotent stem cells. Tissue Eng. Part A, 22: 449-460.
    CrossRef  |  Direct Link  |  
  20. Park, K.M., J. Lee, K.H. Hussein, S.H. Hong, S.R. Yang, E. Lee and H.M. Woo, 2016. Generation of liver-specific TGF-α/c-Myc-overexpressing porcine induced pluripotent stem-like cells and blastocyst formation using nuclear transfer. J. Vet. Med. Sci., 78: 709-713.
    CrossRef  |  Direct Link  |  
  21. Mousa, H.M., K.H. Hussein, H.R. Pant, H.M. Woo, C.H. Park and C.S. Kim, 2016. In vitro degradation behavior and cytocompatibility of a bioceramic anodization films on the biodegradable magnesium alloy. Colloids Surf., A: Physicochem. Eng. Aspects, 488: 82-92.
    CrossRef  |  Direct Link  |  
  22. Mousa, H.M., K.H. Hussein, A.A. Raslan, J. Lee, H.M. Woo, C.H. Park and C.S. Kim, 2016. Amorphous apatite thin film formation on a biodegradable Mg alloy for bone regeneration: Strategy, characterization, biodegradation, and in vitro cell study. RSC Adv., 6: 22563-22574.
    CrossRef  |  Direct Link  |  
  23. Ingole, V.H., K.H. Hussein, A.A. Kashale, K.P. Gattu and S.S. Dhanayat et al., 2016. In vitro bioactivity and osteogenic activity study of solid state synthesized nano-hydroxyapatite using recycled eggshell bio-waste. ChemistrySelect, 1: 3901-3908.
    CrossRef  |  Direct Link  |  
  24. Hussein, K.H., K.M. Park, K.S. Kang and H.M. Woo, 2016. Heparin-gelatin mixture improves vascular reconstruction efficiency and hepatic function in bioengineered livers. Acta Biomater., 38: 82-93.
    CrossRef  |  Direct Link  |  
  25. Hussein, K.H., K.M. Park, K.S. Kang and H.M. Woo, 2016. Biocompatibility evaluation of tissue-engineered decellularized scaffolds for biomedical application. Mater. Sci. Eng.: C, 67: 766-778.
    CrossRef  |  Direct Link  |  
  26. Hussein, K.H., K.M. Park, J.H. Ghim, S.R. Yang and H.M. Woo, 2016. Three dimensional culture of HepG2 liver cells on a rat decellularized liver matrix for pharmacological studies. J. Biomed. Mater. Res., 104: 263-273.
    CrossRef  |  Direct Link  |  
  27. Abdal-Hay, A., K.H. Hussein, L. Casettari, K.A. Khalil and A.S. Hamdy, 2016. Fabrication of novel high performance ductile poly (lactic acid) nanofiber scaffold coated with poly (vinyl alcohol) for tissue engineering applications. Mater. Sci. Eng.: C, 60: 143-150.
    CrossRef  |  Direct Link  |  
  28. Park, K.M., K.H. Hussein, J.H. Ghim, C. Ahn and S.H. Cha et al., 2015. Hepatic differentiation of porcine embryonic stem cells for translational research of hepatocyte transplantation. Transplant. Proc., 47: 775-779.
    CrossRef  |  Direct Link  |  
  29. Park, K.M., K.H. Hussein, H.S. Nam, H.M. Kim and B.M. Kang et al., 2015. A novel mouse model of diabetes mellitus using unilateral nephrectomy. Lab. Anim., 50: 88-93.
    CrossRef  |  Direct Link  |  
  30. Park, K.M., H.S. Kang, K.H. Hussein, H.M. Kim, H.H. Kwak and H.M. Woo, 2015. Identifying the degree of major histocompatibility complex matching in genetically unrelated dogs with the use of microsatellite markers. Transplant. Proc., 47: 780-783.
    CrossRef  |  Direct Link  |  
  31. Mousa, H.M., K.H. Hussein, H.M. Woo, C.H. Park and C.S. Kim, 2015. One-step anodization deposition of anticorrosive bioceramic compounds on AZ31B magnesium alloy for biomedical application. Ceram. Int., 41: 10861-10870.
    CrossRef  |  Direct Link  |  
  32. Hussein, K.H., K.M. Park, H.M. Kim, P.K. Teotia, J.H. Ghim and H.M. Woo, 2015. Construction of a biocompatible decellularized porcine hepatic lobe for liver bioengineering. Int. J. Artif. Organs, 38: 96-104.
    CrossRef  |  Direct Link  |  
  33. Ghim, J.H., K.H. Hussein, K.M. Park and H.M. Woo, 2015. Hepatic cell encapsulation using a decellularized liver scaffold. Biomed. Eng. Lett., 5: 58-64.
    CrossRef  |  Direct Link  |  
  34. Park, K.M., H.S. Nam, P.K. Teotia, K.H. Hussein, S.H. Hong, J.I. Yun and H.M. Woo, 2014. Kidney injury molecule-1 is involved in the chemotactic migration of mesenchymal stem cells. In Vitro Cell. Dev. Biol. Anim., 50: 648-655.
    CrossRef  |  Direct Link  |  
  35. Teotia, P.K., K.E.D. Hussein, K.M. Park, S.H. Hong and S.M. Park et al., 2013. Mouse adipose tissue-derived adult stem cells expressed osteogenic specific transcripts of osteocalcin and parathyroid hormone receptor during osteogenesis. Transplant. Proc., 45: 3102-3107.
    CrossRef  |  Direct Link  |  
  36. Hussein, K.H., K.M. Park, P.K. Teotia, S.H. Hong and S.R. Yang et al., 2013. Sterilization using electrolyzed water highly retains the biological properties in tissue-engineered porcine liver scaffold. Int. J. Artif. Organs, 36: 781-792.
    CrossRef  |  Direct Link  |  
  37. Hussein, K.H., K.M. Park, P.K. Teotia, J.W. Yang and H.M. Kim et al., 2013. Fabrication of a biodegradable xenoantigen-free rat liver scaffold for potential drug screening applications. Transplant. Proc., 45: 3092-3096.
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  38. Hussein, K.H., 2012. Surgical correction of salivary fistula in a buffalo (Bubalis bubalis) using a polyethylene tube as a stent Hussein. Fac. Vet. Med., 6: 69-72.
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  39. Hussein, K.H., 2011. An unusual huge abscess in a buffalo bull (Bubalis bubalis): Case report. Niger. Vet. J., 32: 63-64.
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