Dr. Amr Salah Abouzied
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Dr. Amr Salah Abouzied

Department of Pharmaceutical Chemistry
College of Pharmacy, University of Hail, KSA

Highest Degree
Ph.D. in Pharmaceutical Organic Chemistry from Cairo University, Egypt

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Area of Interest:

Chemistry
100%
Synthesis of Heterocyclic Molecules
62%
Bioactive Heterocyclic Compounds
90%
Bio-Organic Chemistry
75%
Bioactive Natural Products
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
9
Abstracts
8

Selected Publications

  1. Mohammed, H.A., A.S. Abouzied, S.A.A. Mohammed and R.A. Khan, 2023. In vivo and in silico analgesic activity of Ficus populifolia extract containing 2-O-β-D-(3′,4′,6′-Tri-acetyl)-glucopyranosyl-3-methyl pentanoic acid. Int. J. Mol. Sci., Vol. 24. 10.3390/ijms24032270.
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  2. Elshibani, F.A., H.A. Mohammed, A.S. Abouzied, A.K. Abdulkarim and R.A. Khan et al., 2023. Phytochemical and biological activity profiles of Thymbra linearifolia: An exclusively native species of Libyan Green mountains. Arabian J. Chem., Vol. 16. 10.1016/j.arabjc.2023.104775.
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  3. Alosaimy, A.M., A.S. Abouzied, A.M.R. Alsaedi, A. Alafnan and A. Alamri et al., 2023. Discovery of novel indene-based hybrids as breast cancer inhibitors targeting Hsp90: Synthesis, bio-evaluation and molecular docking study. Arabian J. Chem., Vol. 16. 10.1016/j.arabjc.2023.104569.
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  4. Alghamdi, A., A.S. Abouzied, A. Alamri, S. Anwar and M. Ansari et al., 2023. Synthesis, molecular docking, and dynamic simulation targeting main protease (Mpro) of new, Thiazole clubbed pyridine scaffolds as potential COVID-19 inhibitors. Curr. Issues Mol. Biol., 45: 1422-1442.
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  5. Alamri, A., A. Alafnan, B. Huwaimel, A.S. Abouzied and J. Alanazi et al., 2023. Synthesis of novel series of heterocyclic compounds having two azoles against methicillin-sensitive Staphylococcus aureus. J. Mol. Struct., Vol. 1277. 10.1016/j.molstruc.2022.134863.
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  6. Abouzied, A.S., M.K.B. Break, B. Huwaimel, W. Hussein, A. Alafnan and K.M. Younes, 2023. Discovery of a novel synthetic thiazole-benzimidazole conjugate that acts as a potent pancreatic lipase inhibitor using in silico and in vitro approaches. Indian J. Pharm. Educ. Res., 57: 218-227.
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  7. Younes, K.M., M.K. Bin, R. Unissa, A.A. Almarshdi and F.M. Alharbi et al., 2022. In-vitro evaluation of anti-microbial and cytotoxic activity of Artemisia judaica leaves and stem extracts via induction of caspase dependent apoptosis. Indian J. Pharm. Educ. Res., 56: s52-s57.
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  8. Ikram, M., S. Mutahir, M. Humayun, M.A. Khan, J.Y. Al-Humaidi, M.S. Refat and A.S. Abouzied, 2022. Facile synthesis of ZIF-67 for the adsorption of methyl green from wastewater: Integrating molecular models and experimental evidence to comprehend the removal mechanism. Molecules, Vol. 27. 10.3390/molecules27238385.
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  9. Break, M.K.B., K.M. Younes, S. Elkahoui, R. Unissa, S.A. Alfahidat, K.S. Alshawi and A.S. Abouzied, 2022. Achillea fragrantissima (Forssk.) Sch.Bip. methanolic extract exerts potent antimicrobial activity and causes cancer cell death via induction of caspase-dependent apoptosis and S-phase arrest. Nat. Prod. Res., 36: 4639-4644.
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  10. Abouzied, A.S., M.M. Abd-Rabo, B. Huwaimel, S.A. Almahmoud and A.A. Almarshdi et al., 2022. In silico pharmacokinetic profiling of the identified bioactive metabolites of Pergularia tomentosa L. latex extract and in vitro cytotoxic activity via the induction of caspase-dependent apoptosis with S-phase arrest. Pharmaceuticals, Vol. 15. 10.3390/ph15091132.
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  11. Abouzied, A.S., J.Y. Al-Humaidi, A.S. Bazaid, H. Qanash and N.K. Binsaleh et al., 2022. Synthesis, molecular docking study, and cytotoxicity evaluation of some novel 1,3,4-thiadiazole as well as 1,3-thiazole derivatives bearing a pyridine moiety. Molecules, Vol. 27. 10.3390/molecules27196368.
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  12. Abu-Melha, S., Z.A. Muhammad, A.S. Abouzid, M.M. Edrees, A.S.A. Dena, S. Nabil and S.M. Gomha, 2021. Multicomponent synthesis, DFT calculations and molecular docking studies of novel thiazolyl-pyridazinones as potential antimicrobial agents against antibiotic-resistant bacteria. J. Mol. Struct., Vol. 1234. 10.1016/j.molstruc.2021.130180.
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  13. Abu-Melha, S., S.M. Gomha, A.S. Abouzied, M.M. Edrees, A.S. Abo Dena and Z.A. Muhammad, 2021. Microwave-assisted one pot three-component synthesis of novel bioactive thiazolyl-pyridazinediones as potential antimicrobial agents against antibiotic-resistant bacteria. Molecules, Vol. 26. 10.3390/molecules26144260.
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  14. Unnisa, A., A.S. Abouzied, B. Anupama, K.N.V.C. Lakshmi and T. Hussain et al., 2020. Design, synthesis, characterization, computational study and in-vitro antioxidant and anti-inflammatory activities of few novel 6-aryl substituted pyrimidine azo dyes. Arabian J. Chem., 10.1016/j.arabjc.2020.09.050.
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  15. Ads, E.N., A.S. Abouzied and M.K. Alshammari, 2020. Evaluation of cytotoxic effects of methanolic extract of Pergularia tomentosa L growing wild in KSA. Asian Pacific J. Cancer Prevention, 21: 67-72.
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  16. Mohareb, R.M., A.S. Abouzied and N.S. Abbas, 2019. Synthesis and biological evaluation of novel 4,5,6,7-Tetrahydrobenzo[D]-Thiazol-2- Yl derivatives derived from dimedone with anti-tumor, c-met, tyrosine kinase and pim-1 inhibitions. Anti-Cancer Agents Med. Chem., 19: 1438-1453.
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  17. Althagafi, I.I., A.S. Abouzied, T.A. Farghaly, N.T. Al-Qurashi, M.Y. Alfaifi, M.R. Shaaban and M.R.A. Aziz, 2018. Novel nano-sized bis-indoline derivatives as antitumor agents. J. Heterocyclic Chem., 56: 391-399.
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  18. Mohamed, A.A., A.S. Abouzied and F.I. Hamed, 2017. Synthesis and cytotoxicity of thiophene, thieno[2,3-C]Pyrazole, Thieno[2,3-D]pyrimidine and pyridine derivatives derived from 2-acetylfuran. Int. J. Chem. Mater. Res., 5: 1-14.
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  19. Hamed, F.I., A.A. Mohamed and A.S. Abouzied, 2017. The uses of 2-amino-4-phenylthiazole in the synthesis of coumarin, pyran, pyridine and thiazole derivatives with antitumor activities. Open Access Lib. J., 04: 1-14.
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  20. Samir, E.M., A.S. Abouzied and F.I. Hamed, 2016. The synthesis and cytotoxicity of novel thiophene derivatives derived from 2-(4-oxo-4,4-dihydrothiazol-2-yl) acetonitrile. Int. J. Organic Chem., 06: 85-94.
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  21. Mohareb, R.M., S.M. Sherif, W.W. Wardakhan and A.S. Abouzied, 2014. New approaches for the use of acetoacetanilide in the synthesis of thiophenes and their fused derivatives with anti-tumor activity. Open Access Lib. J., 01: 1-16.
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  22. Wardakhan, W.W., S.M. Sherif, R.M. Mohareb and A.S. Abouzied, 2012. The reaction of cyanoacetylhdrazine with furan-2-aldehyde: novel synthesis of thiophene, azole, azine and coumarin derivatives and their antitumor evaluation. Int. J. Organic Chem., 02: 321-331.
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