Dr. Mohammed  Abdullah Al Za`abi
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Dr. Mohammed Abdullah Al Za`abi

Associate Professor
Sultan Qaboos University, Oman


Highest Degree
Ph.D. in Clinical Pharmacokinetics from University of Queensland, Australia

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Biography

Dr. Mohammed Abdullah Al Za`abi is currently working as Associate Professor at College of Medicine & Health Sciences, Sultan Qaboos University, Oman. He has completed his Ph.D. in Clinical Pharmacy from University of Queensland, Australia. His area of specialization includes Clinical Pharmacokinetics, Therapeutic Drug Monitoring. Previously he was appointed as Sabbatical Fellow at College of Pharmacy, University of Rhode Island, USA. He also attended number of workshops and trainings. He has supervised 6 MSc thesis. Dr. Abdullah is also serving as member of many scientific societies such as Oman Medical Society, Oman Medical Registry, Arab Union of Pharmacology, Australian Society of Clinical & Experimental Pharmacologists & Toxicologists, Population Pharmacokinetics Approach Group in Europe, International Association of Therapeutic Drug Monitoring & Clinical Toxicology, Oman Society of Lipid and Atherosclerosis, American Association for Clinical Chemistry, International Atherosclerosis Association and American College of Clinical Pharmacology. He is author and co-author of 36 journal papers.

Area of Interest:

Pharmacology and Toxicology
100%
Clinical Pharmacokinetics
62%
Therapeutic Drug Monitoring
90%
Nephrotoxicity
75%
Chromatography
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ali, B.H., S. Al-Salam, Y. Al Suleimani, J. Al Kalbani and S. Al Bahlani et al., 2018. Curcumin ameliorates kidney function and oxidative stress in experimental chronic kidney disease. Basic Clin. Pharmacol. Toxicol., 122: 65-73.
    CrossRef  |  Direct Link  |  
  2. Ali, B.H., M. Al Za'abi, T. Karaca, Y. Al Suleimani and K.A. Al Balushi et al., 2018. Potassium bromate-induced kidney damage in rats and the effect of gum acacia thereon. Am. J. Transl. Res., 10: 126-137.
    PubMed  |  Direct Link  |  
  3. Al Za'abi, M., S. Al Salam, Y. Al Suleimani, P. Manoj, A. Nemmar and B.H. Ali, 2018. Gum acacia improves renal function and ameliorates systemic inflammation, oxidative and nitrosative stress in streptozotocin-induced diabetes in rats with adenine-induced chronic kidney disease. Cell. Physiol. Biochem., 45: 2293-2304.
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  4. Salman, B., M. Al-Za'abi, M. Al-Huneini, D. Dennison and A. Al-Rawas et al., 2017. Therapeutic drug monitoring-guided dosing of busulfan differs from weight-based dosing in hematopoietic stem cell transplant patients. Hematol./Oncol. Stem Cell Ther., 10: 70-78.
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  5. Opletal, L., L. Chocholousova-Havlikova, T. Siatka, L. Cahlikova and M. Locarek et al., 2017. Preparation and validated analysis of anthocyanin concentrate from the calyces of Hibiscus sabdariffa. Nat. Prod. Commun., 12: 44-45.
    Direct Link  |  
  6. Ali, B.H., T. Karaca, Y. Al Suleimani, M. Al Za'abi, J. Al Kalbani, M. Ashique and A. Nemmar, 2017. The effect of swimming exercise on adenine-induced kidney disease in rats and the influence of curcumin or lisinopril thereon. PLoS ONE, Vol. 12. 10.1371/journal.pone.0176316.
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  7. Ali, B.H., L. Cahlikova, L. Opletal, T. Karaca and P. Manoj et al., 2017. Effect of aqueous extract and anthocyanins of calyces of Hibiscus sabdariffa (Malvaceae) in rats with adenine‐induced chronic kidney disease. J. Pharm. Pharmacol., 69: 1219-1229.
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  8. Al-Hashar, A., I. Al-Zakwani, T. Eriksson and M. Al Za'abi, 2017. Whose responsibility is medication reconciliation: Physicians, pharmacists or nurses? A survey in an academic tertiary care hospital. Saudi Pharmaceut. J., 25: 52-58.
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  9. Al Za'abi, M., A. Shalaby, P. Manoj and B.H. Ali, 2017. The in vivo effects of adenine-induced chronic kidney disease on some renal and hepatic function and CYP450 metabolizing enzymes. Physiol. Res., 66: 263-271.
    PubMed  |  Direct Link  |  
  10. Al Suleimani, Y.M., A.S. Al Mahruqi, A. Za'abi, A. Shalaby, M. Ashique, A. Nemmar and B.H. Ali, 2017. Effect of diesel exhaust particles on renal vascular responses in rats with chronic kidney disease. Environ. Toxicol., 32: 541-549.
    CrossRef  |  Direct Link  |  
  11. Za'abi, M.A., B.H. Ali, Z.A. Alothman and I. Ali, 2016. Analyses of acute kidney injury biomarkers by ultra-high performance liquid chromatography with mass spectrometry. J. Sep. Sci., 39: 69-82.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Za'abi, A., 2016. Advances in the methodologies for the analysis of acute kidney injury biomarkers. Curr. Biomarkers, 6: 81-92.
    Direct Link  |  
  13. Ali, B.H., M. Al Za'abi, S.A. Adham, J. Yasin, A. Nemmar and N. Schupp, 2016. Therapeutic effect of chrysin on adenine-induced chronic kidney disease in rats. Cell. Physiol. Biochem., 38: 248-257.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Al Balushi, K.A., M.A. Alzaabi and F. Alghafri, 2016. Prescribing pattern of antifungal medications at a tertiary care hospital in Oman. J. Clin. Diagn. Res., 10: FC27-FC30.
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  15. Alothman, Z.A., A. Al-Warthan, H.Y. Aboul-Enein, M.A. Za'abi and I. Ali, 2015. Mechanistic approaches of PHE and PPF columns for separation of rasberry ketone and caffeine. J. Liq. Chromatogr. Related Technol., 38: 1324-1332.
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  16. Ali, B.H., S.A. Adham, M. Al Za'abi, M.I. Waly, J. Yasin, A. Nemmar and N. Schupp, 2015. Ameliorative effect of chrysin on adenine-induced chronic kidney disease in rats. Plos One, Vol. 10. 10.1371/journal.pone.0125285.
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  17. Ali, B.H., S. Al-Salam, A. Za'abi, K.A. Al Balushi and A.S. AlMahruqi et al., 2015. Renoprotective effects of gamma-aminobutyric acid on cisplatin-induced acute renal injury in rats. Basic Clin. Pharmacol. Toxicol., 116: 62-68.
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  18. Ali, B.H., M. Al Za'abi, A. Shalaby, P. Manoj and M.I. Waly et al., 2015. The effect of thymoquinone treatment on the combined renal and pulmonary toxicity of cisplatin and diesel exhaust particles. Exp. Biol. Med., 240: 1698-1707.
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  19. Ali, B.H., M. Al Za'abi, A. Al Shukaili and A. Nemmar, 2015. High-mobility group box-1 protein in adenine-induced chronic renal failure and the influence of gum Arabic thereon. Physiol. Res., 64: 147-151.
    PubMed  |  Direct Link  |  
  20. Al Za'abi, M., M. Al Busaidi, J. Yasin, N. Schupp, A. Nemmar and B.H. Ali, 2015. Development of a new model for the induction of chronic kidney disease via intraperitoneal adenine administration and the effect of treatment with gum acacia thereon. Am. J. Transl. Res., 7: 28-38.
    PubMed  |  
  21. Al Za'abi, M., J. Al Muqbali and K. Al-Waili, 2015. Sampling time and indications appropriateness for therapeutically monitored drugs at a teaching university hospital in Oman. Saudi Pharm. J., 23: 458-462.
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  22. Al Suleimani, Y.M., M. Al Za'abi, A. Ramkumar, A.S. Al Mahruqi, M.H. Tageldin, A. Nemmar and B.H. Ali, 2015. Influence of treatment with gum acacia on renal vascular responses in a rat model of chronic kidney disease. Eur. Rev. Med. Pharmacol. Sci., 19: 498-506.
    Direct Link  |  
  23. Ali, B.H., S. Al-Salam, M. Al Za'abi, K.A. Al Balushi and A. Ramkumar et al., 2014. Does swimming exercise affect experimental chronic kidney disease in rats treated with gum acacia? Plos One, Vol. 9. 10.1371/journal.pone.0102528.
    CrossRef  |  PubMed  |  Direct Link  |  
  24. Ali, B.H., M. Alza'abi, A. Ramkumar, I. Al-Lawati and M.I. Waly et al., 2014. The effect of activated charcoal on adenine-induced chronic renal failure in rats. Food Chem. Toxicol., 65: 321-328.
    CrossRef  |  PubMed  |  Direct Link  |  
  25. Ali, B.H., M. Al Za'abi, A. Ramkumar, J. Yasin and A. Nemmar, 2014. Anemia in adenine-induced chronic renal failure and the influence of treatment with gum acacia thereon. Physiol. Res., 63: 351-358.
    PubMed  |  Direct Link  |  
  26. Ali, B.H., I. Inuwa, A. Za'abi, S. Al Bahlani and H. Al Issaei et al., 2014. Renal and myocardial histopathology and morphometry in rats with adenine-induced chronic renal failure: Influence of gum acacia. Cell. Physiol. Biochem., 34: 818-828.
    CrossRef  |  PubMed  |  Direct Link  |  
  27. Al Za'abi, M., S.A.A. Al-Hinai and S. Al-Busaidi, 2014. Utilization pattern of antipsychotics at a tertiary care hospital in Oman. J. Psychiatry, Vol. 17. 10.4172/Psychiatry.1000171.
    CrossRef  |  Direct Link  |  
  28. Al Za'abi, M., A.S. Al Jabri and K.J. Al Bartamani, 2014. Utilization pattern of anti-depressants at a tertiary hospital in Oman: A retrospective analysis. J. Psychiatry, Vol. 17. 10.4172/Psychiatry.1000163.
    CrossRef  |  Direct Link  |  
  29. Al Balushi, K.A., M. Al-Haddabi, I. Al-Zakwani and M. Al Za'abi, 2014. Glycemic control among patients with type 2 diabetes at a primary health care center in Oman. Primary Care Diabetes, 8: 239-243.
    CrossRef  |  PubMed  |  Direct Link  |  
  30. Za'abi, A., R. Ahmed, A. Al Asmi and I. Al-Zakwani, 2013. Utilization patterns of antiepileptic drugs among adult epileptic patients at a tertiary hospital in Oman. Int. J. Pharm. Pract., 21: 117-122.
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  31. Saleh, M.A., R.N. Mafiana, M. Al Za'abi, R. Vaishnav, S. Al Kindi and I. Al-Zakwani, 2013. Epidemiology of chemotherapy-induced neutropenia at a tertiary university hospital in Oman. Int. J. Clin. Pharm., 35: 1036-1039.
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  32. Ali, I., A. Haque, W.A. Wani, K. Saleem and A. Za'abi, 2013. Analyses of anticancer drugs by capillary electrophoresis: A review. Biomed. Chromatogr., 27: 1296-1311.
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  33. Ali, B.H., S. Beegam, I. Al Lawati, M. Waly, M. Al Za'abi and A. Nemmar, 2013. Comparative efficacy of three brands of gum acacia on adenine-induced chronic renal failure in rats. Physiol. Res., 62: 47-56.
  34. Ali, B.H., S. Al-Salam, M. Al Za'abi, M.I. Waly and A. Ramkumar et al., 2013. New model for adenine-induced chronic renal failure in mice and the effect of gum acacia treatment thereon: Comparison with rats. J. Pharmacol. Toxicol. Methods, 68: 384-393.
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  35. Al Za'abi, M., S. Shafiq, D. Al Riyami and B.H. Ali, 2013. Utilization pattern of vancomycin in a university teaching hospital in Oman: Comparison with international guidelines. Trop. J. Pharm. Res., 12: 117-121.
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  36. Al Za'abi, M., B.H. Ali, A. Hussain and I. Ali, 2013. Fast HPLC analysis of adenine in human plasma using a new generation C28 column and different extraction methods. Analy. Meth., 5: 1487-1493.
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  37. Al Za'abi, M., A. Al Asmi, R. Ahmed, S. Al-Masrouri, R. Al-Lawati, R. Nandhagopal and I. Al-Zakwani, 2013. Therapeutic antiepileptic drug monitoring pattern in a tertiary care hospital in Oman. Afr. J. Pharm. Pharmacol., 7: 58-62.
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  38. Ali, I., Z.A. Al-Othman and M. Al-Za'abi, 2012. Superficially porous particles columns for super fast HPLC separations. Biomed. Chromatogr., 26: 1001-1008.
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  39. Al-Zakwani, I., K. Sulaiman, M. Al Za'abi, P. Panduranga and K. Al-Habib et al., 2012. Impact of evidence-based cardiac medication on short-and long-term mortality in 7,567 acute coronary syndrome patients in the Gulf RACE-II registry. Int. J. Clin. Pharmacol. Ther., 50: 418-425.
  40. Al Za'abi, M., B.H. Ali and M. Al Toubi, 2012. HPLC-Fluorescence method for measurement of the uremic toxin indoxyl sulfate in plasma. J. Chromatogr. Sci., 51: 40-43.
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  41. Ali, B.H., M. Al-Za'abi, G. Blunden and A. Nemmar, 2011. Experimental gentamicin nephrotoxicity and agents that modify it: A mini-review of recent research. Basic Clin. Pharmacol. Toxicol., 9: 225-232.
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  42. Ali, B.H., S. Al-Salam, I. Al Husseni, R.R. Kayed and N. Al-Masroori et al., 2010. Effects of gum arabic in rats with adenine-induced chronic renal failure. Exp. Biol. Med., 235: 373-382.
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  43. Al Za'abi, M., T. Donovan, D. Tudehope, P. Woodgate, L.A. Collie and B. Charles, 2007. Orogastric and intravenous indomethacin administration to very premature neonates with patent ductus arteriosus: Population pharmacokinetics, absolute bioavailability and treatment outcome. Ther. Drug Monit., 29: 807-814.
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  44. Al Za'abi, M.A., G.H. Dehghanzadeh, R.L.G. Norris and B.G. Charles, 2006. A rapid and sensitive microscale HPLC method for the determination of indomethacin in plasma of premature neonates with patent ductus arteriousus. J. Chromatogr. B, 830: 364-367.
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  45. Al Za'abi, M., A. Lanner, X. Xiaonian, T. Donovan and B. Charles, 2006. Application of routine monitoring data for determination of the population pharmacokinetics and enteral bioavailability of phenytoin in neonates and infants with seizures. Ther. Drug Monit., 28: 793-799.
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  46. Mohammed, A.Z., D. Deleu and C. Batchelor, 2003. Salivary free concentrations of anti-epileptic drugs: An evaluation in a routine clinical setting. Acta Neurol. Belg., 103: 19-23.
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