Dr. Arif-ullah Khan
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Dr. Arif-ullah Khan

Associate Professor
Riphah International University, Pakistan

Highest Degree
PostDoc Fellow in Pharmacology from University of Malaya, Malaysia

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Area of Interest:

Pharmacology and Toxicology
100%
Autonomic Pharmacology
62%
Neuropharmacology
90%
Hepatoprotectives
75%
Biomedicine
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Tanzeel-ur-Rehman, K. Arif-ullah and A. Abbas, 2017. Antioxidant, antimicrobial, cytotoxic, anticancer, anti-inflammatory, analgesic activities and molecular docking investigation of nepetolide: A natural diterpene. Nat. Prod. Commun., .
  2. Saleem, M., K. Arif-ullah, F. Ali and F. Noreen, 2017. Protective effect of Parthenium hysterophorus against carbon tetrachloride and paracetamol-induced hepatotoxicity in rabbits. Trop. J. Pharm. Res., .
  3. Raza, Q., K. Arif-ullah and H. Nadeem, 2017. In-silico investigation, in-vivo anticonvulsant and analgesic effects of novel hydrazide derivatives. Acta Poloniae Pharm. Drug Res., .
  4. Qazi, N.G., K. Arif-ullah and F. Ali, 2017. Pharmacological basis for medicinal use of Acacia modesta in hyperactive gastrointestinal disorders. BMC Pharmacol. Toxicol., .
  5. Minhas, A.M., K. Arif-ullah and M.M. Ansari, 2017. Anti-inflammatory effect of Caralluma edulis in acute and chronic inflammation; An explanation of possible underlying biochemical mechanisms. J. Anim. Plant Sci., .
  6. Minhas, A.M., K. Arif-ullah and G.A. Miana, 2017. Anti-inflammatory activity of Berberis lycium in acute and chronic models of inflammation. J. Anim. Plant Sci., .
  7. Khan, A.W and K. Arif-ullah, 2017. Phytochemical composition and antidepressant action of Solanum surattense. J. Herbs Spices Med. Plants, .
  8. Khan, A., M. Mehwis, S. Wadood and K. Arif-ullah, 2017. The in silico identification of small molecules for protein-protein interaction inhibition in AKAP-Lbc-RhoA signaling complex. Comput. Biol. Chem., 67: 84-91.
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  9. Hussain, S., U. Farhat and K. Arif-ullah, 2017. In vitro cytotoxicity of crude and subsequent fractions of Anchusa arvensis against human lung cancer cell line NCI-H460. (UITO-2016-0440). Int. J. Toxicol., .
  10. Hussain, M., K. Arif-ullah, N.G. Qazi and F. Ali, 2017. Pharmacological basis for the medicinal use of Ziziphus nummularia in gastrointestinal disorders. Front. Pharmacol., .
  11. Firdoos, S., K. Arif-ullah and F. Ali, 2017. Pharmacological investigation of Aesculus indica for its anti-nociceptive action. J. Anim. Plant Sci., .
  12. Firdoos, S., K. Arif-ullah and F. Ali, 2017. Anti-nociceptive effect of caralluma edulis on peripheral and central pain pathways-possible underlying pharmacodynamics. Sains Malaysiana, .
  13. Aslam, H., K. Arif-ullah, F. Ali, H. Nadeem and S.M. Shah, 2017. Anti-diabetic activity of Heliotropium strigosum in alloxan-induced diabetic mice. Asian Biomed., .
  14. Aslam, H., K. Arif-ullah and F. Ali, 2017. In-vitro and in-vivo pharmacological investigation of Conyza canadensis for its anti-diabetic effect. BMC Complementary Altern. Med., .
  15. Aslam, H., H. Aslam and K. Arif-ullah, 2017. Computational evaluation of selected natural compounds for antidiabetic potential. Front. Pharmacol., .
  16. Arif-ullah, K., A.H. Gilani, S. Ali, M. Ahmed, A.K. Marwat and M.I. Choudhary, 2017. Antispasmodic, bronchodilator, vasorelaxant and cardiosuppressant effects of Buxus papillosa. BMC Complementary Altern. Med., 10.1186/s12906-017-1558-x.
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  17. Arif, N., H. Nadeem, Z.R. Paracha, F. Ali and K. Arif-ullah, 2017. Synthesis, anti-inflammatory activity and docking analysis of 4,5-disubstituted-1,2,4-triazole thioacetate derivatives. Arabian J. Chem., .
  18. Afridi, F., K. Arif-ullah, F. Ali and H. Nadeem, 2017. In-silico, invitro and in-vvo investigation of novel oxadiazole and pyrazole derivatives. BMC Pharmacol. Toxicol., .
  19. Abbas, A., K. Arif-ullah, F. Ali, H. Afzal and K. Imran, 2017. Synthesis, characterization, antioxidant, antimicrobial, cytotoxic, anticancer, leishmanicidal, anti-inflammatory activities and docking studies of heterocyclic 1,3,4-oxadiazoles and 4-amino-1,2,4-triazoles derivatives. J. Chem. Soc. Pak., .
  20. Khan, S.U., K. Arif-ullah, A.H.A. Shah, S.M. Shah, S. Hussain, M. Ayaz and S. Ayaz, 2016. Heavy metals content, phytochemical composition, antimicrobial and insecticidal evaluation of Elaeagnus angustifolia. Toxicol. Ind. Health, 32: 154-161.
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  21. Khan, A.W., K. Arif-ullah and T. Ahmed, 2016. Anticonvulsant, anxiolytic, and sedative activities of verbena officinalis. Front. Pharmacol., 7: 1-8.
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  22. Farman, K., K. Arif-ullah, A. Khan, J. Hussain and A.H. Gilani, 2016. Spasmolytic and Ca++ channel blocking potential of nepetolide: Isolated from Nepeta suavis. Nat. Prod. Commun., 11: 591-592.
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  23. Shah, S.M., S. Hussain, A. Khan, A.H.A. Shah, H. Khan, F. Ullah and Barkatullah, 2015. Cytotoxic and phytotoxic actions of Heliotropium strigosum. Toxicol. Ind. Health, 31: 429-432.
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  24. Shah, S.M., M. Ayaz, A. Khan, F. Ullah and Farhan et al., 2015. 1,1-Diphenyl,2-picrylhydrazyl free radical scavenging, bactericidal, fungicidal and leishmanicidal properties of Teucrium stocksianum. Toxicol. Ind. Health, 31: 1037-1043.
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  25. Rahman, N., M. Riaz, K. Arif-ullah, Z. Haq and L. Dima, 2015. Mechanism of anti-inflammatory and anti-nociceptive actions of Acacia modesta in animal models. Pak. J. Zool., 47: 1723-1730.
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  26. Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2015. Blood pressure lowering, vasodilator and cardiac-modulatory potential of Carum roxburghianum seed extract. Clin. Exp. Hypertens., 37: 102-107.
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  27. Ayaz, M., F. Subhan, J. Ahmed, K. Arif-ullah and U. Farhat et al., 2015. Citalopram and venlafaxene differentially augments antimicrobial properties of antibiotics. Acta Poloniae Pharm. Drug Res., 72: 1269-1278.
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  28. Ayaz, M., F. Subhan, J. Ahmed, A. Khan and F. Ullah et al., 2015. Sertraline enhances the activity of antimicrobial agents against pathogens of clinical relevance. J. Biol. Res. Thessaloniki, 10.1186/s40709-015-0028-1.
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  29. Arif-ullah, K and A.H. Gilani, 2015. Urinary bladder relaxant effect of Artemisia vulgaris and Aspalathus linearis. J. Anim. Plant Sci., 25: 1779-1781.
    Direct Link  |  
  30. Arif-ullah, K and A.H. Gilani, 2015. Natural products useful in respiratory disorders: focus on side-effect neutralizing combinations. Phytother. Res., 29: 1265-1285.
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  31. Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2014. Blood pressure lowering Morus alba is mediated through Ca++ antagonist pathway. Int. J. Pharmacol., 10: 225-230.
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  32. Khan, M., F. Subhan, K. Arif-ullah, M. Abbas, G. Ali, K. Rauf and A.H. Gilani, 2014. Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats. Pharm. Biol., 52: 586-590.
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  33. Khan, M., A.U. Khan, Najeeb‐ur‐ Rehman and A.H. Gilani, 2014. Pharmacological basis for the medicinal use of Lens culinaris in gastrointestinal and respiratory disorders. Phytother. Res., 28: 1349-1358.
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  34. Khan, M., A.U. Khan, N.U. Rehman and A.H. Gilani, 2014. Cardiovascular inhibitory properties of Lens culinaris. Bangladesh J. Pharmacol., 9: 303-306.
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  35. Khan, I.U., J.A. Khader, F.U. Khan, K. Arif-ullah and U. Muhib et al., 2013. Carbonic anhydrase and urease inhibitory effects of Sonchus asper. Life Sci. J., 10: 2705-2707.
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  36. Ullah, Z., K.M. Baloch, J.A. Khader, N.M. AbdElsalam and K. Arif-ullah et al., 2012. Comparative analysis of distinct diuretics through urine analysis. Afr. J. Pharm. Pharmacol., 6: 1977-1981.
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  37. Rehman, S., Z. Awan, K. Arif-ullah, A.H. Shah, A. Rahman and I. Gul, 2012. Antibacterial potential of Skemmia laureola methanolic extract. Global Adv. Res. J. Microbiol., 1: 90-93.
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  38. Najeeb-ur-Rehman, K. Arif-ullah, K.M. Alkharfy and A.H. Gilani, 2012. Pharmacological basis for the medicinal use of Lepidium sativum in airways disorders. Evidence-Based Complement. Altern. Med., Vol. 2012. 10.1155/2012/596524.
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  39. Khan, M., Najeeur-Rehman, K. Arif-ullah and A.H. Gilani, 2012. Pharmacological basis for the medicinal use of Morus alba in gut and airways disorders. Bangladesh J. Pharmacol., 7: 289-298.
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  40. Khan, M., K. Arif-ullah, N. Rehman, M.A. Zafar, A. Hazrat and A.H. Gilani, 2012. Cardiovascular effects of Juniperus excelsa are mediated through multiple pathways. Clin. Exp. Hypertens., 34: 209-216.
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  41. Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2012. Pharmacological explanation for the medicinal use of Juniperus excelsa in hyperactive gastrointestinal and respiratory disorders. J. Nat. Med., 66: 292-301.
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  42. Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2012. Gut and airways relaxant effects of Carum roxburghianum. J. Ethnopharmacol., 141: 938-946.
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  43. Khan, A., A. Rahim, Z. Iqbal and A.H. Gilani, 2012. Insights into mechanisms underlying the gut and airways modulatory effects of Swertia chirata. J. Nat. Med., 66: 140-148.
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  44. Khan, A. and A.H. Gilani, 2012. Antidiarrhoeal and bronchodilatory potential of Valeriana wallichii. Nat. Prod. Res., 26: 1045-1049.
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  45. Ismail, A., J. Hussain, K. Arif-ullah, A.L. Khan and L. Ali et al., 2012. Antibacterial, antifungal, cytotoxic, phytotoxic, insecticidal, and enzyme inhibitory activities of Geranium wallichianum. Evidence-Based Complementary Alter. Med., 10.1155/2012/305906.
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  46. Haq, R.U., I.U. Shah, Z. Ullah, R.A. Khan and A. Malik, 2012. Antitussive and toxicological evaluation of Vitex negundo. Natural Prod. Res., 26: 484-488.
    PubMed  |  
  47. Arif-ullah, K., U. Riaz, A. Khan, M.R. Mustafa, J. Hussain, D.D. Murugan and A.H.B. Hadi, 2012. Vasodilator effect of Phlomis bracteosa constituents is mediated through dual endothelium-dependent and-independent pathways. Clin. Exp. Hypertens., 34: 132-139.
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  48. Arif-ullah, K., M.R. Mustafa, A. Khan and D.D. Morgan, 2012. Hypotensive effect of Gentiana floribunda is mediated through Ca++ antagonism pathway. BMC Complementary Alter. Med., 10.1186/1472-6882-12-121.
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  49. Ahmad, I., A.U. Khan, B.A. Chaudhary, K.H. Janbaz and M. Uzair et al., 2012. Antifungal and antispasmodic activities of the extracts of Euphorbia granulata. J. Med. Plants Res., 6: 19-23.
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  50. Khan, H.U., I. Ali, A.U. Khan, R. Naz and A.H. Gilani, 2011. Antibacterial, antifungal, antispasmodic and Ca++ antagonist effects of Caesalpinia bonducella. Nat. Prod. Res., 25: 444-449.
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  51. Khan, A.U. and A.H. Gilani, 2011. Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium. Phytother. Res., 25: 577-583.
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  52. Khan, A., Q.J. Khan and A.H. Gilani, 2011. Pharmacological basis for the medicinal use of cardamom in asthma. Bangladesh J. Pharmacol., 6: 34-37.
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  53. Khan, A., A.H. Gilani, M. Khan and F. Subhan, 2011. Pharmacological explanation for medicinal use of St. John's Wort in the hypo-motility disorder of gut. Latin Am. J. Pharm., 30: 580-583.
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  54. Khan, A. and A.H. Gilani, 2011. Antidiarrheal and bronchodilatory activities of olive extract. Latin Am. J. Pharm., 30: 5-9.
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  55. Hussain, J., R. Ullah, A. Khan, F. Mabood, M.R. Shah, A.A. Harrasi and A.H. Gilani, 2011. Antispasmodic and Ca++ antagonist potential of marrubiin, a labdane type diterpene from Phlomis bracteosa. J. Pharm. Res., 4: 178-180.
  56. Arif-ullah, K., F. Ali, D. Faraz and A.H. Gilani, 2011. Gut modulatory effects of Daphne oleoides are mediated through cholinergic and Ca++ antagonist mechanisms. Pharm. Biol., 49: 821-825.
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  57. Arif-ullah, K., A.H. Gilani and N. Rehman, 2011. Pharmacological studies on Hypericum perforatum fractions and constituents. Pharm. Biol., 49: 46-56.
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  58. Arif-ullah, K and A.H. Gilani, 2011. Pharmacological basis for the use of Valeriana wallichii in constipation. Latin Am. J. Pharm., 30: 186-188.
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  59. Ali, F., I. Ali, H. Khan, K. Arif-ullah and A.H. Gilani, 2011. Studies on Buddleja asiatica antibacterial, antifungal, antispasmodic and Ca++ antagonist activities. Afr. J. Biotechnol., 10: 7679-7683.
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  60. Khan, H., I. Ali, K. Arif-ullah, M. Ahmed and Z. Shah et al., 2010. Purification and biochemical characterization of alkaline serine protease from Caesalpinia bonducella. Nat. Prod. Commun., 5: 931-934.
    PubMed  |  
  61. Khan, A., M. Khan, F. Subhan and A.H. Gilani, 2010. Antispasmodic, bronchodilator and blood pressure lowering properties of Hypericum oblongifolium - possible mechanism of action. Phytother. Res., 24: 1027-1032.
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  62. Khan, A. and A.H. Gilani, 2010. Airways and cardiovascular inhibitory effects of Olea europea and Terminalia bellerica aqueous fractions. Farmacia, 58: 758-763.
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  63. Hussain, S., M. Jamil, F. Ullah, A. Khan, F. Ullah and S. Ahmed, 2010. Antimicrobial and antioxidant activities of the plant Heliotropium strigosum. Afr. J. Biotechnol., 9: 7738-7743.
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  64. Hussain, J., F.U. Khan, S.A. Gilani, G. Abbas and S. Ahmed et al., 2010. Antiglycation, antiplatelets aggregation, cytotoxic and phytotoxic activities of Nepeta suavis. Latin Am. J. Pharmacy, 29: 573-578.
    Direct Link  |  
  65. Hussain, J., F. Khan, I. Khan, Riazullah and K. Arif-ullah, 2010. Antifungal and Immunomodulatory potential of Nepeta suavis. Am. Eurasian J. Agric. Environ. Sci., 7: 689-692.
    Direct Link  |  
  66. Gilani, S.N., A.U. Khan and A.H. Gilani, 2010. Pharmacological basis for the medicinal use of Zanthoxylum armatum in gut, airways and cardiovascular disorders. Phytother. Res., 24: 553-558.
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  67. Gilani, A.H., A. Khan, A. Khan, S. Bashir and N. Rehman et al., 2010. Pharmacological basis for the medicinal use of Holarrhena antidysenterica in gut motility disorders. Pharm. Biol., 48: 1240-1246.
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  68. Arif-ullah, K and A.H. Gilani, 2010. In vivo studies on bronchodilatory and analgesic activities of Hysocyamus niger and Aspalathus linearis. Latin Am. J. Pharm., 29: 777-782.
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  69. Arif-ullah, K and A.H. Gilani, 2010. Analgesic and antisecretory activities of Terminalia bellerica. Afr. J. Biotechnol., 9: 2717-2719.
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  70. Khan, A.U. and A.H. Gilani, 2009. Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx. J. Ethnopharmacol., 126: 480-486.
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  71. Khan, A. and A.H. Gilani, 2009. Antidiarrheal, antisecretory, and bronchodilatory activities of Hypericum perforatum. Pharm. Biol., 47: 962-967.
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  72. Gilani, A.H., M.H. Mehmood, K.H. Janbaz, A. Khan and S.A. Saeed, 2009. Gut modulatory and antiplatelet activities of Viscum cruciatum. Pharm. Biol., 47: 955-961.
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  73. Gilani, A.H., Q. Jabeen, A.U. Khan and A.J. Shah, 2008. Gut modulatory, blood pressure lowering, diuretic and sedative activities of cardamom. J. Ethnopharmacol., 115: 463-472.
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  74. Gilani, A.H., M.H. Mehmood, K.H. Janbaz, A.U. Khan and S.A. Saeed, 2008. Ethnopharmacological studies on antispasmodic and antiplatelet activities of Ficus carica. J. Ethnopharmacol., 119: 1-5.
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  75. Gilani, A.H., A.U. Khan, T. Ali and S. Ajmal, 2008. Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. J. Ethnopharmacol., 116: 528-538.
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  76. Gilani, A.H., A.U. Khan, M. Raoof, M.N. Ghayur, B.S. Siddiqui, W. Vohra and S. Begum, 2008. Gastrointestinal, selective airways and urinary bladder relaxant effects of Hyoscyamus niger are mediated through dual blockade of muscarinic receptors and Ca2+ channels. Fundam. Clin. Pharmacol., 22: 87-99.
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  77. Arif-ullah, K and A.H. Gilani, 2008. Cardiovascular inhibitory effects of Hyoscyamus niger. Meth. Findings Exp. Clin. Pharmacol., 30: 295-300.
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  78. Arif-ullah K and A.H. Gilani, 2008. Pharmacodynamic evaluation of Terminalia bellerica for its antihypertensive effect. J. Food Drug Anal., 16: 6-14.
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  79. Subhan, F., M. Khan, M. Ibrar, Nazar-ul- Islam, A. Khan and A.H. Gilani, 2007. Antagonism of antinociceptive effect of hydro-ethanolic extract of Hypericum perforatum Linn. By a non selective opioid receptor antagonist, Naloxone. Pak. J. Biol. Sci., 10: 792-796.
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  80. Gilani, A.H., S. Bashir and A.U. Khan, 2007. Pharmacological basis for the use of Borago officinalis in gastrointestinal, respiratory and cardiovascular disorders. J. Ethnopharmacol., 114: 393-399.
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  81. Yaeesh, S., Q. Jamal, A.U. Khan and A.H. Gilani, 2006. Studies on hepatoprotective, antispasmodic and calcium antagonist activities of the aqueous-methanol extract of Achillea millefolium. Phytother. Res., 20: 546-551.
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  82. Khan, A. and A.H. Gilani, 2006. Selective bronchodilatory effect of Rooibos tea (Aspalathus linearis) and its flavonoid, chrysoeriol. Eur. J. Nutr., 45: 463-469.
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  83. Gilani, A.H., K. Arif-ullah and M.N. Ghayur, 2006. Ca2+ antagonist and cholinergic activities explain the medicinal use of olive in gut disorders. Nutr. Res., 26: 277-283.
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  84. Gilani, A.H., A. Khan, M.N. Ghayur, S.F. Ali and J.W. Herzig, 2006. Antispasmodic Effects of Rooibos Tea (Aspalathus linearis) is Mediated Predominantly through K+-Channel Activation. Basic Clin. Pharmacol. Toxicol., 99: 365-373.
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  85. Gilani, A.H., K.H. Bashir, K.H. Janbaz and A. Khan, 2005. Pharmacological basis for the use of fumaria indica in constipation and disrrheoa. J. Ethnopharmacol., 96: 585-589.
  86. Gilani, A.H., I.A. Bukhari, R.A. Khan, A.U. Khan, F. Ullah and V.U. Ahmad, 2005. Cholinomimetic and calcium channel blocking activities of Carthamus oxycantha. Phytother. Res., 19: 679-683.
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  87. Gilani, A.H., A.U. Khan, Q. Jabeen, F. Subhan and R. Ghafar, 2005. Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation. J. Ethnopharmacol., 100: 347-352.
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  88. Gilani, A.H., A.U. Khan, A.J. Shah, J. Connor and Q. Jabeen, 2005. Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int. J. Food Sci. Nutr., 56: 613-620.
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  89. Gilani, A.H., A. Khan, F. Subhan and M. Khan, 2005. Antisposmodic and bronchodilator activities of St. Johns Wort are putatively mediated through dual inhibition of calcium influx and phosphodiaestrases fund. Clin. Pharmacol. J. Compilat., 19: 695-705.