Dr. Abdul Sadiq
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Dr. Abdul Sadiq

Assistant Professor
University of Malakand, Pakistan

Highest Degree
Ph.D. in Organic Synthesis from Jacobs University Bremen, Germany

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Area of Interest:

Pharmacology and Toxicology
100%
Organic Synthesis
62%
Alternative Medicine
90%
Natural Products
75%
Pharmacy
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
39
Abstracts
0

Selected Publications

  1. Sultana, N., M. Sarfraz, S. Tahir, M. SafwanAkram, A. Sadiq, U. Rashid and M.I. Tariq, 2017. Synthesis, crystal structure determination, biological screening and docking studies of N 1-substituted derivatives of 2, 3-dihydroquinazolin-4 (1H)-one as inhibitors of cholinesterases. Bioorg. Chem., 72: 256-267.
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  2. Sarfraz, M., N. Sultana, U. Rashid, M.S. Akram, A. Sadiq and M.I. Tariq, 2017. Synthesis, biological evaluation and docking studies of 2, 3-dihydroquinazolin-4 (1H)-one derivatives as inhibitors of cholinesterases. Bioorg. Chem., 70: 237-244.
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  3. Ayaz, M., S. Fazal, A. Sadiq,F. Ullah, J. Abdul and D.E.S. Robert, 2017. Cellular efflux transporters and the potential role of natural products in combating efflux mediated drug resistance. Front. Bio. Sci., 22: 732-756.
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  4. Ayaz, M., A. Sadiq, M. Junaid, F. Ullah, F. Subhan and J. Ahmad, 2017. Neuroprotective and anti-aging potentials of essential oils from aromatic and medicinal plants. Frontiers Aging Neurosci. (In Press). .
  5. Zeb, A., S. Ahmad, F. Ullah, M. Ayaz and A. Sadiq, 2016. Anti-nociceptive activity of ethnomedicinally important analgesic plant Isodon rugosus Wall. ex Benth: Mechanistic study and identifications of bioactive compounds. Front. Pharmacol., Vol. 7. 10.3389/fphar.2016.00200.
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  6. Zeb, A., A. Sajjad, U. Farhat, A. Muhammad, U. Farman, A. Nawab and S. Abdul, 2016. Evaluation of crude saponins, methanolic extract and subsequent fractions from Isodon rugosus: potentials of anti-angiogenesis in egg and anti-tumorigenesis in potato. Pak. J. Pharm. Sci., .
  7. Ullah, F., M. Ayaz, A. Sadiq, A. Hussain, S. Ahmad, M. Imran and A. Zeb, 2016. Phenolic, flavonoid contents, anticholinestrase and antioxidant evaluation of Iris germanica var; florentina. Nat. Prod. Res., 30: 1440-1444.
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  8. Ullah, F., I. Naveed, A. Muhammad, S. Abdul, U. Ihsan, A. Sajjad and I. Muhammad, 2016. DPPH, ABTS free radical scavenging, antibacterial and phytochemical evaluation of crude methanolic extract and subsequent fractions of Chenopodium botrys aerial parts. Pak. J. Pharm. Sci., .
  9. Sadiq, A., A. Sadiq, A. Rahmat, A. Fawad and A. Sajjad et al., 2016. Antibacterial and antifungal potentials of the solvent extracts from Eryngium caeruleum, Notholirion thomsonianum and Allium consanguineum. BMC Complementary Altern. Med., 10.1186/s12906-016-1465-6.
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  10. Rahim, H., S. Abdul, K. Shahzeb, A.C. Kamran, A. Fazli, A.K. Mir and A. Sudhair, 2016. Isolation and preliminary evaluation of Mulva neglecta mucilage: A novel tablet binder. Braz. J. Pharm. Sci., 52: 201-210.
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  11. Imran, M., R.S. Muhammad, U. Farhat, U. Shafi and M.A.E. Abdelbary et al., 2016. Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of Levofloxacin. Drug Delivery, 10.1080/10717544.2016.1214991.
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  12. Imran, M., M.R. Shah, F. Ullah, S. Ullah and A.M.A. Elhissi et al., 2016. Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime. Int. J. Pharma., 505: 122-132.
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  13. Imran, M., M.R. Shah, F. Ullah, S. Ullah and A. Sadiq et al., 2016. Double-tailed Acyl glycoside niosomal nanocarrier for enhanced oral bioavailability of Cefixime. Artif. Cells Nanomed. Biotechnol., 10.1080/21691401.2016.1246451.
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  14. Ayaz, M., M. Junaid, F. Ullah, A. Sadiq and F. Subhan et al., 2016. Molecularly characterized solvent extracts and saponins from Polygonum hydropiper L show high anti-angiogenic, anti-tumor, brine shrimp and fibroblast NIH/3T3 cell line cytotoxicity. Front. Pharmacol., 10.3389/fphar.2016.00074.
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  15. Ayaz, M., J. Muhammad, U. Farhat, S. Abdul, O. Muhammad, A. Waqar, A. Sajjad and Z. Anwar, 2016. Chemical profiling of bioactive compounds, antimicrobial and insecticidal evaluations of Polygonum hydropiper L. BMC Complementary Altern. Med., .
  16. Ali, N., U. Nimat, Q. Muhammad, R. Hazir, N.K. Shahid, S. Abdul and A. Muhammad, 2016. Molecular characterization and growth optimization of halo-tolerant protease producing Bacillus subtilis strain BLK-1.5 Isolated from salt mines of Karak, Pakistan. Extremophiles, 20: 395-402.
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  17. Ahmad, S., U. Farhat, Z. Anwar, A. Muhammad, U. Farman and S. Abdul, 2016. Evaluation of Rumex hastatus D. Don for cytotoxic potential against HeLa and NIH/3T3 cell lines: Chemical characterization of chloroform fraction and identification of bioactive compounds. BMC Complementary Altern. Med., 10.1186/s12906-016-1302-y.
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  18. Ahmad, S., F. Ullah, M. Ayaz, A. Zeb, F. Ullah and A. Sadiq, 2016. Antitumor and anti-angiogenic potentials of isolated crude saponins and various fractions of Rumex hastatus D. Don. Biol. Res., 10.1186/s40659-016-0079-2.
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  19. Ahmad, S., F. Ullah, A. Sadiq, M. Ayaz and M. Imran et al., 2016. Chemical composition, antioxidant and anticholinesterase potentials of essential oil of Rumex hastatus D. Don collected from the North West of Pakistan. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-0998-z.
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  20. Ahmad, S., F. Iftikhar, F. Ullah, A. Sadiq and U. Rashid, 2016. Rational design and synthesis of dihydropyrimidine based dual binding site acetylcholinesterase inhibitors. Bioorg. Chem., 69: 91-101.
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  21. Shah, S.M.H., S.M.M. Shah, Z. Ahmad, M. Yaseen and M.R. Shah et al., 2015. Phytochemicals, in vitro antioxidant, total phenolic contents and phytotoxic activity of Cornus macrophylla wall bark collected from the north-west of Pakistan. Pak. J. Pharmaceut. Sci., 28: 23-28.
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  22. Sadiq, A., F. Mahmood, F. Ullah, M. Ayaz and S. Ahmad et al., 2015. Synthesis, Anticholinesterase and antioxidant potentials of ketoesters derivatives of succinimides: a possible role in the management of Alzheimer`s. Chem. Cent. J., 10.1186/s13065-015-0107-2.
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  23. Rahim, H., A.K. Mir, S. Abdul, K. Shahzeb, A.C. Kamran and U.R. Inayat, 2015. Comparative studies of binding potential of Prunus armeniaca and Prunus domestica gums in tablets formulations. Pak. J. Pharm. Sci., 28: 909-914.
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  24. Nisar, M., M.M.S. Syed, K. Imran, Sheema, S. Abdul, K. Shahzeb and M.H.S. Syed, 2015. Larvicidal, insecticidal, brine shrimp cytotoxicity and anti-oxidant activities of Diospyros kaki (L.) reported from Pakistan. Pak. J. Pharm. Sci., 28: 1239-1243.
  25. Kamal, Z., U. Farhat, A. Sajjad, A. Muhammad and S. Abdul et al., 2015. Saponins and solvent extracts from Atriplex laciniata (L.) show high anthelmintic and insecticidal activity. J. Traditional Chin. Med., .
  26. Kamal, Z., Midrarullah, A. Sajjad, U. Farhat, S. Abdul, A. Muhammad, Z. Anwar and I. Muhammad, 2015. Ex-Vivo antibacterial, phytotoxic and cytotoxic potential in the crude natural phytoconstituents of Rumex hastatus D. Don. Pak. J. Bot., 47: 293-299.
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  27. Kamal, Z., F. Ullah, M. Ayaz, A. Sadiq and S. Ahmad et al., 2015. Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of Atriplex laciniata L.: potential effectiveness in Alzheimer's and other neurological disorders. Biol. Res., 10.1186/s40659-015-0011-1.
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  28. Ayaz, M., M. Junaid, F. Ullah, A. Sadiq and M.A. Khan et al., 2015. Comparative chemical profiling, cholinesterase inhibitions and anti-radicals properties of essential oils from Polygonum hydropiper L: A Preliminary anti- Alzheimer`s study. Lipids Health Dis., 14: 141-141.
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  29. Ayaz, M., F. Subhan, J. Ahmed, A. Khan and F. Ullah et al., 2015. Citalopram and Venlafaxine differentially augments antimicrobial properties of antibiotics. Acta Poloniae Pharmaceutica. Drug Res., 72: 1269-1278.
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  30. Ahmad, S., F. Ullah, M. Ayaz, A. Sadiq and M. Imran, 2015. Antioxidant and anticholinesterase investigations of Rumex hastatus D. Don: potential effectiveness in oxidative stress and neurological disorders. Biol. Res., 10.1186/s40659-015-0010-2.
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  31. Zeb, A., A. Sadiq, F. Ullah, S. Ahmad and M. Ayaz, 2014. Phytochemical and toxicological investigations of crude methanolic extracts, subsequent fractions and crude saponins of Isodon rugosus. Biol. Res., 10.1186/0717-6287-47-57.
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  32. Zeb, A., A. Sadiq, F. Ullah, S. Ahmad and M. Ayaz, 2014. Investigations of anticholinestrase and antioxidant potentials of methanolic extract, subsequent fractions, crude saponins and flavonoids isolated from Isodon rugosus. Biol. Res., 10.1186/0717-6287-47-76.
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  33. Shah, S.M.M., A. Sadiq, S.M. Shah and F. Ullah, 2014. Antioxidant, total phenolic contents and antinociceptive potential of Teucrium stocksianum methanolic extract in different animal models. BMC Complementary Altern. Med., 14: 181-181.
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  34. Ayaz, M., M. Junaid, J. Ahmed, F. Ullah, A. Sadiq, S. Ahmad and M. Imran, 2014. Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L. BMC Complementary Altern. Med., 14: 145-145.
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  35. Ayaz, M., M. Junaid, F. Subhan, F. Ullah and A. Sadiq et al., 2014. Heavy metals analysis, phytochemical, phytotoxic and anthelmintic investigations of crude methanolic extract, subsequent fractions and crude saponins from Polygonum hydropiper L. BMC Complementary Altern. Med., 10.1186/1472-6882-14-465.
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  36. Shah, S.M.M., F. Ullah, S.M.H. Shah, M. Zahoor and A. Sadiq, 2012. Analysis of chemical constituents and antinociceptive potential of essential oil of Teucrium Stocksianum bioss collected from the North West of Pakistan. BMC Complementary Altern. Med., 12: 244-244.
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  37. Nugent, T.C., S. Abdul, B. Ahtaram, H. Thomas, L.Z. Lei, V. Nina and S.B. Bassem, 2012. Noncovalent bifunctional organocatalysts: Powerful tools for contiguous quaternary-tertiary stereogenic carbon formation, scope, and origin of enantioselectivity. Chem. A Eur. J., 18: 4088-4098.
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  38. Nugent, T.C., B. Ahtaram, S. Abdul, S. Mohammad, M.N. Umar and N.T. Foad, 2012. Chiral picolylamines for michael and aldol reactions: Probing substrate boundaries. Org. Biomol. Chem., 10: 9287-9294.
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  39. Nugent, T.C., E.N. Daniela, M. El-Shazly, H. Dan, S. Abdul, B. Ahtaram and N.U. Muhammad, 2011. Sequential reductive amination-hydrogenolysis: a one-pot synthesis of challenging chiral primary amines. Adv. Synth. Catal., 353: 2085-2092.
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