Mr. Rajeev Kumar  Singla
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Mr. Rajeev Kumar Singla

Post-Doctor
Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Sichuan, China


Highest Degree
Ph.D. in Applied Science from University of Delhi, Delhi, India

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Biography

Rajeev Kumar Singla was born in 1986 at Meham, Rohtak (Haryana), India. He obtained his B.Pharm in 2007 from Maharshi Dayanand University, Rohtak and M.Pharm in Pharmaceutical Chemistry in 2009 from Manipal University, Karnataka. He has submitted his PhD thesis on May, 2018 and received his PhD (Doctorate) degree from Faculty of Technology, University of Delhi, India in year 2019.

He is at present associated with Institutes for Systems Genetics, West China Hospital, Sichuan University, Chengdu, Sichuan (China) as Post Doctor with a broad experience in secondary metabolites isolation, computational chemistry (docking, QSAR, ADME and Toxicological Predictions) and synthetic chemistry. Singla is also Founder and Chief Editor of Indo Global Journal of Pharmaceutical Sciences and Guest Associate Editor of Frontiers in Chemistry, and member of the Sigma-Aldrich Global Advisory Board, The Science Advisory Board, the Asian Council of Science Editors, and the Non-profit research community Ebola Research Initiative, along with a Honorary Faculty Membership at the Novel Global Community Educational Foundation (NGCEF), Australia.

He has bagged more than 100 publications in journals of high repute.

Institutions
Post Doctor - Institutes for System Genetics, West China Hospital of Sichuan University from 2020 until present
Assistant Professor - School of Medical and Allied Sciences, K.R. Mangalam University from 2018 until 2019
Senior Scientific Assistant and Nodal Officer-Store & Purchase (BSE) - Division of Biological Sciences and Engineering, Netaji Subhas Inst of Technology from 2015 until 2018
SERB-Young Scientist - Biological Sciences and Engineering, Netaji Subhas University of Technology from 2012 until 2014

Area of Interest:

Pharmacology and Toxicology
100%
Molecular Modeling
62%
Computational Chemistry
90%
Phytochemistry
75%
Medicinal Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Singla, R.K., A. Sultana, M.S. Alam and B. Shen, 2020. Regulation of pain genes-capsaicin vs resiniferatoxin: reassessment of transcriptomic data. Front. Pharmacol., 10.3389/fphar.2020.551786.
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  2. Singla, R.K., 2020. Secondary metabolites as treatment of choice for metabolic disorders and infectious diseases and their metabolic profiling: part 1. Curr. Drug Metab., 21: 480-481.
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  3. Singla, R.K. and B. Shen, 2020. In silico ADME-T evaluation of natural DPP-IV inhibitors for rational drug design against diabetes. Curr. Drug Metab., Vol. 21. 10.2174/1389200221999200901202945.
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  4. Shen, L., K. Shen, J. Bai, J. Wang, R.K. Singla and B. Shen, 2020. Data-driven microbiota biomarker discovery for personalized drug therapy of cardiovascular disease. Pharmacol. Res., 10.1016/j.phrs.2020.105225.
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  5. Shen, B., R.K. Singla, T. Agarwal and H. Xuefei, 2020. Herbal resources to combat a progressive & degenerative nervous system disorder - parkinson’s disease. Curr. Drug Targets, 10.2174/1389450121999201013155202.
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  6. Singla, R.K., R. Kumar, S. Khan, Mohit, K. Kumari and A. Garg, 2019. Natural products: potential source of DPP-IV inhibitors. Curr. Protein Pept. Sci., 20: 1218-1225.
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  7. Singla, R.K., A.K. Dubey, A. Garg, R.K. Sharma and M. Fiorino et al., 2019. Natural polyphenols: chemical classification, definition of classes, subcategories, and structures. J. Aoac. Int., 102: 1397-1400.
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  8. Singla, R.K. and A.K. Dubey, 2019. Molecules and metabolites from natural products as inhibitors of biofilm in Candida spp. pathogens. Curr. Topics Med. Chem., 19: 2567-2578.
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  9. Sharma, R.K., M. Micali, A. Pellerito, A. Santangelo, S. Natalello, R. Tulumello and R.K. Singla, 2019. Studies on the determination of antioxidant activity and phenolic content of plant products in India (2000–2017). J. Aoac. Int., 102: 1407-1413.
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  10. Laganà, P., G. Anastasi, F. Marano, S. Piccione and R.K. Singla et al., 2019. Phenolic substances in foods: health effects as anti-inflammatory and antimicrobial agents. J. Aoac. Int., 102: 1378-1387.
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  11. Dubey, A.K. and R.K. Singla, 2019. Perspectives on anti-candida drug development. Curr. Topics Med. Chem., 19: 2375-2376.
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  12. Dubey, A.K. and R.K. Singla, 2019. Current trends in anti-candida drug development. Curr. Topics Med. Chem., 19: 2525-2526.
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  13. Srivastava, V., R.K. Singla and A.K. Dubey, 2018. Inhibition of biofilm and virulence factors of Candida albicans by partially purified secondary metabolites of Streptomyces chrestomyceticus strain ADP4. Curr. Topics Med. Chem., 18: 925-945.
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  14. Srivastava, V., R.K. Singla and A.K. Dubey, 2018. Emerging virulence, drug resistance and future anti-fungal drugs for candida pathogens. Curr. Topics Med. Chem., 18: 759-778.
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  15. Singla, R.K., M. Ali, M.A. Kamal and A.K. Dubey, 2018. Isolation and characterization of nuciferoic acid, a Novel Keto fatty acid with hyaluronidase inhibitory activity from Cocos nucifera Linn. Endocarp. Curr. Top. Med. Chem., 18: 2367-2378.
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  16. Singla, R.K. and A.K. Dubey, 2018. Phytochemical profiling, GC-MS analysis and a-amylase inhibitory potential of ethanolic extract of Cocos nucifera Linn. endocarp. Endocr., Metab. Immune Disord. - Drug Targets, 19: 419-442.
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  17. Singla, R.K., L. Scotti and A.K. Dubey, 2017. In silico studies revealed multiple neurological targets for the antidepressant molecule ursolic acid. Curr. Neuropharmacol., 15: 1100-1106.
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  18. Scotti, L., J.F. Mendonca, H. Ishiki, F.F. Ribeiro and K.S. Rajeev et al., 2017. Docking studies for multi-target drugs. Curr. Drug Targets, 18: 592-604.
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  19. Sahu, D., S. Sharma, R.K. Singla and A.K. Panda, 2017. Antioxidant activity and protective effect of suramin against oxidative stress in collagen induced arthritis. Eur. J. Pharmaceut. Sci., 101: 125-139.
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  20. Putta, S., I. Peluso, N.S. Yarla, E.K. Kilari, A. Bishayee, D.Y. Lu and R.K. Singla, 2017. Diabetes mellitus and male aging: Pharmacotherapeutics and clinical implications. Curr. Pharm. Des., 23: 4475-4483.
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  21. Singla, R.K., R. Singh and Kumar A. Dubey, 2016. Important aspects of post-prandial antidiabetic drug, acarbose. Curr. Topics Med. Chem., 16: 2625-2633.
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  22. Scotti, L., R.K. Singla, H.M. Ishiki, F.J.B. Medonca, Jr., M.S. da Silva, J.M.B. Filho and M.T. Scotti, 2016. Recent advances in natural hyaluronidase inhibitors. Curr. Top. Med. Chem., 16: 2525-2531.
  23. Scotti, L., R.K. Singla and M.T. Scotti, 2016. Natural leads in drug discovery against metabolic disorders and their related infectious diseases. Curr. Top. Med. Chem., 16: 2523-2524.
  24. Mikhailov, S.N., L. Scotti, R.K. Singla, M.T. Scotti, 2016. Perspectives in medicinal chemistry. Curr. Top. Med. Chem., 16: 2725-2726.
  25. De, B., K. Bhandari, R.K. Singla, P. Katakam and T. Samanta et al., 2016. Chemometrics optimized extraction procedures, phyto syner gistic blending and In vitro screening of natural enzyme inhibi tors amongst leaves of tulsi, banyan and Jamun. Pharmacognosy Magaz., Vol. 12. .
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  26. Singla, R.K., 2015. Homology modeling of MDR1 gene MDR1_Enthi of E. histolytica & its molecular docking with anti-entamoeba histolytica agents. Curr. Top. Med. Chem., 15: 980-989.
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  27. Singla, R.K., 2015. Editorial (Thematic Issue: In Silico drug design and medicinal chemistry). Curr. Top. Med. Chem., 15: 971-972.
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  28. Gundamaraju, R., R.K. Singla, R.C. Vemuri and S.D. Sekaran, 2015. Functional correlation of medicinal chemistry and entamoeba histolytica treatment: An emphasis on the past, present and future chemotherapy. Mini Rev. Med. Chem., 15: 211-219.
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  29. Gundamaraju, R., R.C. Vemuri, L.S. Kuen, R. Manikam, R.K. Singla, S.D. Sekaran and R. Chakrapani, 2015. The science of rabies in tropical regions: From epidemiological pandemonium to prevention. Frontiers Life Sci., 8: 210-214.
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  30. Aggarwal, B., R.K. Singla, M. Ali, V. Singh, J.O. Igoli, R. Gundamaraju and K.H. Kim, 2015. Triterpenic and monoterpenic esters from stems of Ichnocarpus frutescens and their drug likeness potential. Med. Chem. Res., 24: 1427-1437.
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  31. Vemuri, R.C., R. Gundamaraju and R.K. Singla, 2014. Volumetric Analysis in Oncology. LAP Lambert Academic Publishing. Germany, ISBN -13 (978-3-659-57280-7) Pages:64.
  32. Singla, R.K., G.V. Bhat and H. Gonzalez-Diaz, 2014. Editorial from phytochemistry to medicinal chemistry: Isolation, semisynthesis, evaluation and computational studies. Curr. Top. Med. Chem., 14: 979-980.
  33. Singla, R.K., 2014. Mechanistic evidence to support the anti-hepatitis B viral activity of multifunctional scaffold & conformationally restricted magnolol. Nat. Acad. Sci. Lett., 37: 45-50.
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  34. Pokuri, S., R.K. Singla, V.G. Bhat and G.G. Shenoy, 2014. Insights on the antioxidant potential of 1, 2, 4-triazoles: Synthesis, screening & QSAR studies. Curr. Drug Metab., 15: 389-397.
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  35. Igoli, N.P., C.J. Clements, R.K. Singla, J.O. Igoli, N. Uche and A.I. Gray, 2014. Antitrypanosomal activity & docking studies of components of Crateva adansonii DC leaves: Novel multifunctional scaffolds. Curr. Top. Med. Chem., 14: 981-990.
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  36. Igoli, J.O., A.I. Gray, C.J. Clements, P. Kantheti and R.K. Singla, 2014. Antitrypanosomal activity & docking studies of isolated constituents from the lichen Cetraria islandica: Possibly multifunctional scaffolds. Curr. Top. Med. Chem., 14: 1014-1021.
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  37. Gundamaraju, R., R.C. Vemuri, R.K. Singla, R. Manikam, A.R. Rao and S.D. Sekaran, 2014. Strophanthus hispidus attenuates the Ischemia-Reperfusion induced myocardial Infarction and reduces mean arterial pressure in renal artery occlusion. Pharmacognosy Magazine, 10: 557-562.
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  38. Singla, R.K., A. Kumar, S. Khan, F.A. Qurainy and R. Shrivastava et al., 2011. Evaluation of antimicrobial activity of 3-(4-1H- indol-3-yl)-2,3- dihydro-1H-benzo[b][1,5]diazepin-2-yl)-2H-chromen-2-one. Indo-Global J. Pharm. Sci., 1: 127-133.
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  39. Sharma, O., A. Kotnala, B. Shrivastava and R.K. Singla, 2011. High-throughput screening: Effective tool in drug discovery. Pharmacol. Newsletter, 2: 134-150.
  40. Saini, R. and R.K. Singla, 2011. Renin inhibitor: An overview. Pharmacol. Newsletter, 2: 1085-1104.
  41. Rajendra, K.S., B. Shrivastava, D.M. Gupta and R.K. Singla, 2011. Global issue and regulatory control of pharmacolvigilance system: A standard operating procedure for a new develop organization. Indo-Global J. Pharm. Sci., 1: 142-151.
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  42. Rajeev, K.S., V. Sharma, R. Bhatia and B. Shrivastava, 2011. A review on bioisosterism: A rationale approach for drug design and molecular modification. Pharmacology, 1: 272-299.
  43. Rajeev, K.S., G.R. Bankar, P.G. Nayak, P. Bansal and P. Paul et al., 2011. Vasorelaxant and antihypertensive effect of cocos nucifera linn. Endocarp on isolated rat thoracic aorta and DOCA salt induced hypertensive rats. J. Ethnopharmacol., 134: 50-54.
    PubMed  |  
  44. Rajeev, K.S., B. Jhanwar, V. Sharma and B. Shrivastava, 2011. QSAR-Hansch analysis and related approaches in drug design. Pharmacology, 1: 306-344.
  45. Rajeev, K.S. and S. Khan, 2011. Assessment of genetic diversity in phyllanthus amarus using HPTLC. Indo-Global J. Pharm. Sci., 1: 1-12.
  46. Phogat, D. and R.K. Singla, 2011. Curcumin-A phytoconstituent of choice. Pharmacology, Newsletter, 2: 1055-1071.
  47. Jayalakshmi, S., A. Mishra, A. Mishra, R.K. Singla and A.K. Ghosh et al., 2011. In vitro Evaluation of antioxidant activity of five drugs in Trinpanchmool. Pharmacology, 2: 1153-1159.
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  48. Hooda, V., G.N. Sharma and R.K. Singla, 2011. Smilax zeylanica Linn: A natural therapeutic Hub. Pharmacol. Newsletter, 2: 151-154.
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  49. Ankit, K.R.J., R.K. Singla and B. Shrivastava, 2011. Thiazole: A remarkable antimicrobial and antioxidant agents. Pharmacol. Newsletter, 2: 1072-1084.
  50. Rajeev, K.S., V.K. Verma and B.G. Varadaraj, 2010. Meditation: A potential stress buster. Pharmacol. Newsletter, 2010: 435-438.
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  51. Rajeev, K.S., P. Jain and P. Aggarwal, 2010. Self medication: A subject to review. Pharmacology, 3: 190-192.
  52. Rajeev, K.S., P. Aggarwal, P. Jain and S. Mittal, 2010. Medication errors: Seeks attention. Pharmacology, 3: 173-176.
  53. Rajeev, K.S., B. Aggarwal, M. Ali and V. Singh, 2010. Isolation and characterization of phytoconstituents from the stem of Ichnocarpus frutescens. Chinese J. Nat. Med., 8: 401-404.
    CrossRef  |  
  54. Rajeev, K.S., A. Joseph, A. Pai, K.K. Srinivasan and T. Kedar et al., 2010. Synthesis of novel 3- (substituted 1,3,4-thiadiazol-2-yl)- quinazolin-4(3H)-ones as anticancer agents. Orbital- Electron. J. Chem. Campo Grande, 2: 158-167.
  55. Rajeev, K.S. and B.G. Varadaraj, 2010. QSAR model for predicting the fungicidal action of 1,2,4-triazole derivatives against Candida albicans. J. Enzyme Inhib. Med. Chem., 25: 696-701.
    PubMed  |  
  56. Rajeev, K.S. and B.G. Varadaraj, 2010. Honey bee sting and venom offering active as well as passive immunization could reduce Swine flu pandemic A(H1N1). Med. Hypotheses, 74: 617-618.
    PubMed  |  
  57. Rajeev, S. and V.G. Bhat, 2009. Tuberculosis: A global threat. Pharmacology, 2: 129-167.
  58. Rajeev, K.S., V.B. Reddy, B.G. Varadaraj and G.G. Shenoy, 2009. Synthesis and antimicrobial studies of some novel benzimidazole derivatives. Asian J. Res. Chem., 2: 162-167.
  59. Rajeev, K.S., N.K. Jaiswal and S.N. Singh, 2009. Isolation of escherichia coli and enterobacter aerogens from paneer samples in relation to public health sold under market conditions at Allahabad. Int. J. Food Sci. Technol. Nutr., 3: 53-58.
  60. Rajeev, K.S., M.M. Mudgal, B.G. Varadaraj and S.G. Gautham, 2009. A facile synthesis and antimicrobial activity of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives. Pharmacology, 2: 188-193.
  61. Rajeev, K.S., A. Pai, A. Joseph, T. Kedar and A.T. Thomas et al., 2009. Synthesis, in-vitro and in vivo anticancer activity of substituted imidazolones. Pharmacology, 2: 933-942.
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  62. Rajeev, K.S. and B.G. Varadaraj, 2008. Synthesis and antimicrobial activity of benzimidazole derivatives. Indian J. Pharmacol., 40: 148-149.