Dr. Bhaswat Chakraborty
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Dr. Bhaswat Chakraborty

President/CEO/Company Owner
Cadila Pharmaceuticals Limited, India

Highest Degree
Ph.D. in Clinical Pharmacology from University of Saskatchewan, Canada

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Area of Interest:

Pharmacology and Toxicology
100%
Clinical Pharmacology
62%
Bianalytical Method Development
90%
Biequivalence Trials
75%
Pharmacy
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
19
Abstracts
0

Selected Publications

  1. Raja, C., N, Sagar, and C. Bhaswat, 2014. Recent insights into the association of chronic inflammatory andneurodegenerative processes in clinical depression. J. Funda. Pharma. Res, 2: 57-61.
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  2. Chakraborty B.S., 2014. Pharmacovigilance: curriculum and career. J. Adv. Pharm. Technol. Res, 5: 2-3.
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  3. Sakore, S., and B. Chakraborty, 2013. Formulation and evaluation of enalapril maleate sustained release matrix tablets. Int. J. Pharm. Biomed. Res, 4: 21-26.
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  4. Chakraborty, B.S., 2013. Critical issues in the conduct of antihypertensive clinical trials. J. Pharma. Sci. Tech, 2: 47-55.
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  5. Chakraborty, B.S., 2013. Clinical research in india: the current scenario and prospects. J. Adv. Pharm. Technol. Res, 4: 126-127.
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  6. Sakore, S., and B. Chakraborthy, 2012. IN-VITRO and in-vivo correlation of immediate release acyclovir tablet using wagner nelson method. Int. J. Phaema, 2: 598-604.
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  7. Ghosh, C., and B. Chakraborty, 2012. LC-MS Methods for Regulated Bioequivalence Studies: Do We Need to Worry about Matrix Effects? Omics Online Scientific Reports. Omics. Online. Sci. Rep, 1: 424-429.
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  8. Ghosh, C., V. Jha, C. Patra, R. Ahir and B. Chakraborty, 2012. SIMULTANEOUS determination of docosahexaenoic acid and eicosapentaenoic acid by lc-esi-ms/ms from human plasma. J. Liq. Chromatogr. Related Technol, 35: 1812-1825.
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  9. Ghosh, C., I. Jain, C.P. Shinde and B.S. Chakraborty, 2012. Rapid and sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of enalapril and its major metabolite enalaprilat, in human plasma: Application to a bioequivalence study. Drug Test. Anal., 4: 94-103.
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  10. Ghosh, C., C.P. Shinde, and B. Chakraborty, 2012. Influence of ionization source design on matrix effects during lc-esi-ms/ms analysis. J. Chromatogr. B, 893: 193-200.
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  11. Kumar, A., R. Kachhadiya amd B.S. Chakraborty, 2011. Clinical outcome of patients of acute coronary syndrome at 7 and 30 days undergoing percutaneous coronary interventions and treated with bivalirudin and heparin. Int. J. Contemp. Res. Rev., 2: 31-35.
  12. Ghosh, C., and S. Gaur, C.P. Shinde, and B. Chakraborty, 2011. A systematic approach to overcome the matrix effect during lc-esi-ms/ms analysis by different sample extraction techniques. J. Bioequivalence Bioavailability, 3: 122-127.
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  13. Ghosh, C., V. Jha, C.P. Shinde and B.S. Chakraborty, 2011. A LC-MS analysis of acamprosate from human plasma: pharmacokinetic application. Drug Test. Anal., 3: 735-742.
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  14. Ghosh, C., S. Gaur, A. Singh, C.P. Shinde and B.S. Chakraborty, 2011. Estimation of nevirapine from human plasma by ESI-LC-MS/MS: A pharmacokinetic application. J. Bioequivalence Bioavailability, 3: 20-25.
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  15. Ghosh, C., I. Jain, S. Gaur, N. Patel, A. Upadhyay and B.S. Chakraborty, 2011. Simultaneous estimation of atorvastatin and its two metabolites from human plasma by ESI-LC-MS/MS. Drug Test. Anal., 3: 352-362.
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  16. Ghosh, C., A. Upadhayay, A. Singh, S. Bahadur, and B. S. Chakraborty,et al, 2011. SIMULTANEOUS determination of aspirin and its metabolite from human plasma by uplc-uv detection: application to pharmacokinetic study. J. Liq. Chromatogr. Related Technol, 34: 2326-2338.
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  17. Chakraborty, B.S., 2011. Clinical trials of antihypertensives: Nature of control and design. Indian J. Pharmacol., 43: 13-17.
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  18. Sharma, G.N., B.S. Chakraborty, J. Sanadya, U.S. Baghel, C. Ghosh and M. Singhal, 2010. Bio-analytical estimation of losartan and losartan carboxylic acid concentrations in human plasma by using LC-MS/MS. Int. J. Pharm. Qual. Assur., 2: 13-18.
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  19. Sakore, S., S. Kute, A. Tekade and B.S. Chakraborty, 2010. Long acting in situ gelling vehicle for ophthalmic delivery: A research. Int. J. Drug Formulation Res., 1: 324-348.
  20. Sakore, S., S. Chaudhary and B.S. Chakraborty, 2010. Biowaiver monograph for immediate release solid oral dosage forms: Ofloxacin. Int. J. Pharm. Pharm. Sci., 2: 156-161.
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  21. Patel, C.D., V.D. Modi, B.S. Chakraborty, N. Mathuria, P. Dadhaniya, P.A. Borade and P. Morankar, 2010. Effect of a novel antiinflammatory polyherbal preparation (Sudarshanam oil) on hematological parameters in Wistar rats. Acta Poloinae Pharm. Drug Res., 67: 277-281.
    PubMed  |  
  22. Patel, A., T. Shah, G. Shah, V. Jha and C. Ghosh et al., 2010. Preservation of bioavailability of ingredients and lack of drug-drug interactions in a novel five-ingredient polypill (Polycap ™). Am. J. Cardiovasc. Drugs, 10: 95-103.
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  23. Kute, S.D., S. Sakore and B.S. Chakraborty, 2010. Formulation approaches in ocular drug delivery system. Int. J. Pharm. Sci. Technol., 2: 118-145.
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  24. Kumar, A., R.K. Kachhadiya, V. Vaishnavi and B.S. Chakraborty, 2010. Comparison of tumor response rate and toxicities with polychemotherapy versus monochemotherapy in patients of metastatic breast cancer: A meta-analysis. Int. J. Curr. Res. Rev., 1: 1-9.
  25. Ghosh, C., V. Jha, R. Ahir, S. Shah, C.P. Shinde and B.S. Chakraborty, 2010. A rapid and most sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of alverine and its major metabolite, para hydroxy alverine, in human plasma: Application to a pharmacokinetic and bioequivalence study. Drug Test. Anal., 2: 284-291.
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  26. Ghosh, C., C.P. Shinde and B.S. Chakraborty, 2010. Ionization polarity as a cause of matrix effects, its removal and estimation in ESI-LC-MS/MS bio-analysis. J. Anal. Bioanal. Tech., 1: 106-106.
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  27. Jain, S., V.V. Vaishnavi and B.S. Chakraborty, 2009. The effect of dyslipidemic drugs on mortality: A meta-analysis. Indian J. Pharmacol., 41: 4-8.
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  28. Ghosh, C., R.P. Singh, S. Inamdar, M. Mote and B.S. Chakraborty, 2009. Sensitive, selective, precise and accurate LC-MS method for determination of clonidine in human plasma. Chromatographia, 69: 1227-1232.
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  29. Gavali, D., K.S. Kulkarni, A. Kumar and B.S. Chakraborty, 2009. Therapeutic class specific signal detection of bradycardia associated with propranolol hydrochloride. Ind. J. Pharmacol., 41: 162-166.
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  30. Verma, R.J., B.S. Chakraborty, C. Patel and N. Mathuria, 2008. Curcumin ameliorates aflatoxin-induced changes in SDH and ATPase activities in liver and kidney of mice. Acta Poloinae Pharm. Drug Res., 65: 415-419.
    PubMed  |  
  31. Dadhaniya, P., C. Patel, M. Makwana, K. Vachhani, B.K. Gunale, A. Maseeh and B. Chakraborty, 2008. Safety assessment of tenatoprazole. Acute and subacute toxicity studies. Indian J. Clin. Pract., 19: 23-27.
  32. Pant, M.C., B.S. Chakraborty, N. Patel, S.S. Bisht and V.P. Verma et al., 2007. Role of Cadi-05 as an adjuvant therapy in advanced non small cell lung cancer: P3-022. J. Thoracic Oncol., 2: S616-S616.
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  33. Chakraborty, B.S., 2007. Cancer drug development-key regulatory considerations. Health Admin., 20: 29-36.
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  34. Gallicano, K.D., I.J. McGilveray, S. Qureshi, W. Nitchuk, and B. Chakraborty,et al, 1991. Comparative bioavailability of oral contraceptive products. Clin. Biochem, 24: 107-111.
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  35. Midha, K. K., B. S. Chakraborty, R. Schwede, E. M. Hawes, and G. McKay,et al, 1990. Comparative bioavailability of two tablet formulations of fluphenazine dihydrochloride in drug-free psychiatric patients. J. Pharm. Sci, 79: 3-8.
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  36. Midha KK1, G. McKay, B.S. Chakraborty, M.Young, and E.M.Hawes,et al, 1990. Bioequivalence of two thorazine tablet formulations using radioimmunoassay and gas chromatographic-mass spectrometric methods. J. Pharm. Sci, 79: 196-201.
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  37. Midha, K.K., B.S. Chakraborty, D.A. Ganes, M.M. Hawes, and J.W. Hubbard,et al, 1989. Intersubject variation in the pharmacokinetics of haloperidol and reduced haloperidol. J. Clin. Psychopharmacol, 9: 98-104.
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  38. Midha, K. K., B. S. Chakraborty, E. M. Hawes, J. W. Hubbard, and G. McKay,et al,, 1989. Comparative bioavailability of a new commercial tablet formulation and two lots of a reference formulation of haloperidol. J.Pharm.Sci, 78: 443-447.
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  39. Chakraborty, B.S., J. W. Hubbard, E. M. Hawes, G. McKay, and J. K. Cooper,et al, 1989. Interconversion between haloperidol and reduced haloperidol in healthy volunteers. Eur. J. Clin. Pharmacol, 37: 45-48.
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  40. Chakraborty, B. S., K. K. Midha, G. McKay, E. M. Hawes, and J. W. Hubbard,et al, 1989. Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: A dose proportionality study. J. Pharm. Sci, 78: 769-801.
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  41. Chakraborty, B.S., E.M. Hawes, G. McKay, J.W. Hubbard, and E.D. Korchinski,et al, 1988. S-OXIDATION of thioridazine to psychoactive metabolites: an oral dose-proportionality study in healthy volunteers. Drug. Metabol. Drug. Interact, 6: 425-438.
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  42. Chakraborty B.S., E.M. Hawes and K.K. Midha, 1988. Development of a radioimmunoassay procedure for sulforidazine and its comparison with a high-performance liquid chromatographic method. Ther. Drug. Monit, 10: 205-214.
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  43. Chakraborty, B.S., M. S. Sardessai, T. J. Jaworski, K. K. Midha and E. M. Hawes,et al., 1987. Synthesis and properties of haptens for the development of radioimmunoassays for thioridazine, mesoridazine, and sulforidazine. Pharma. Res, 4: 207-213.
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  44. Chakraborty, B.S., E.M. Hawes and K.K. Midha, 1987. Development of a radioimmunoassay procedure for mesoridazine and its comparison with a high-performance liquid chromatographic method. Ther. Drug. Monit, 9: 464-471.
    PubMed  |