Dr. Pushplata   Prasad
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Dr. Pushplata Prasad

Research Scientist
Teri-Deakin Nanobiotechnology Centre, India


Highest Degree
Ph.D. in Genetics from University of Delhi, Delhi, India

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Biography

Dr. Pushplata Singh obtained her Master’s and PhD degrees in Genetics from the Dept. of Genetics, University of Delhi South Campus, New Delhi in the year 2001 and 2006 respectively. The title of her Ph.D. thesis is “Molecular genetics correlates of Diabetic Chronic renal insufficiency” and using extensive wet lab biotechnology tools along with bio-informatics and bio-statistics expertise established the genes conferring risk to the disease in Indian population. She has 10 years of research experience in the field of Computational Genomics and Molecular Genetics. After completing her PhD she wrote an independent project titled “ Genetic determinants of Alcohol dependence” and was awarded an independent ICMR-Research Associate fellowship for two years at All India Institute of Medical Sciences, New Delhi. In 2009 she was selected as a Research Scientist in a DBT-Centre of Excellence project entitled “Genome wide association study (GWAS) in Rheumatoid Arthritis and Ulcerative Colitis”. The Centre of Excellence project on GWAS was first of its kind in India involved partners from different fields such as Bioinformatics, Biostatistics, Physics, Medicine and Biotechnology. Her principle responsibility was to execute the project by under taking Whole Genome based genetic analysis using Bio-informatics and bio-statistics tools. Besides, she was also assigned the key task of successful co-ordination of project by bridging up the gaps between multiple disciplines.
In her tenure in TERI, Dr. Pushplata has successfully established a Bioinformatics unit and is continuously involved in training students on various computational tools for Genomics and Proteomics. Two of her PhD students are working on the Whole Genome Sequence data analysis of Bio-control and AMF fungi and the group has published 2 research articles from their Computational Genomics work in high impact factor journals (BMC-Genomics and BMC-Evolutionary Biology).

Area of Interest:

Biomedical Sciences
100%
Molecular Tools
62%
Computational Genomics
90%
Genetic Determinants
75%
Genome Annotation
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Varshney, D., A. Jaiswar, A. Adholeya and P. Prasad, 2016. Phylogenetic analyses reveal molecular signatures associated with functional divergence among Subtilisin like serine proteases are linked to lifestyle transitions in hypocreales. BMC Evol. Biol., Vol. 16. 10.1186/s12862-016-0793-y.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Prasad, P., D. Varshney and A. Adholeya, 2015. Whole genome annotation and comparative genomic analyses of bio-control fungus Purpureocillium lilacinum. BMC Genomics, Vol. 16. 10.1186/s12864-015-2229-2.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Juyal, G., S. Negi, A. Sood, A. Gupta and P. Prasad et al., 2015. Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis. Gut, 64: 571-579.
  4. Prasad, P., A. Ambekar and M. Vaswani, 2013. Case-control association analysis of dopamine receptor polymorphisms in alcohol dependence: A pilot study in Indian males. BMC Res. Notes, Vol. 6. 10.1186/1756-0500-6-418.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Negi, S., G. Juyal, S. Senapati, P. Prasad and A. Gupta et al., 2013. A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for rheumatoid arthritis in north Indians. Arthritis Rheumatism, 65: 3026-3035.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Prasad, P., A. Kumar, R. Gupta, R.C. Juyal and B.K. Thelma, 2012. Caucasian and Asian specific rheumatoid arthritis risk loci reveal limited replication and apparent allelic heterogeneity in north Indians. Plos One, Vol. 7. 10.1371/journal.pone.0031584.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Juyal, G., P. Prasad, S. Senapati, V. Midha and A. Sood et al., 2011. An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians. Plos One, Vol. 6. 10.1371/journal.pone.0016565.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Prasad, P., A.K. Tiwari, K.P. Kumar, A.C. Ammini, A. Gupta, R. Gupta and B.K. Thelma, 2010. Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes. BMC Med. Genet., Vol. 11. 10.1186/1471-2350-11-52.
    CrossRef  |  PubMed  |  Direct Link  |  
  9. Prasad, P., A. Ambekar and M. Vaswani, 2010. Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: A preliminary study. BMC Med. Genet., Vol. 11. 10.1186/1471-2350-11-24.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Vaswani, M., P. Prasad and S. Kapur, 2009. Association of ADHIB and ALDH2 gene polymorphisms with alcohol dependence: A pilot study from India. Human Genomics, Vol. 3. 10.1186/1479-7364-3-3-213.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Tiwari, A.K., P. Prasad, B.K. Thelma, K.P. Kumar, A.C. Ammini, A. Gupta and R. Gupta, 2009. Oxidative stress pathway genes and chronic renal insufficiency in Asian Indians with type 2 diabetes. J. Diabetes Complications, 23: 102-111.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Prasad, P., K.P. Kumar, A.C. Ammini, A. Gupta, R. Gupta and B.K. Thelma, 2008. Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes. BMC Genet., Vol. 9. 10.1186/1471-2156-9-26.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Prasad, P., A.K. Tiwari, K.P. Kumar, A.C. Ammini, A. Gupta, R. Gupta and B.K. Thelma, 2007. Association of TGFβ1, TNFα, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians. BMC Med. Genet., Vol. 8. 10.1186/1471-2350-8-20.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Prasad, P. and B.K. Thelma, 2007. Normative genetic profiles of RAAS pathway gene polymorphisms in north Indian and south Indian populations. Hum. Biol., 79: 241-254.
    Direct Link  |  
  15. Prasad, P., A.K. Tiwari, K.M.P. Kumar, A.C. Ammini and G. Arvind et al., 2006. Chronic renal insufficiency among Asian Indians with type 2 diabetes: I. Role of RAAS gene polymorphisms. Biol. Med. Genet., 7: 42-42.