Dr. Mymoona  Akhter
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Dr. Mymoona Akhter

Associate Professor
Hamdard University, India


Highest Degree
Ph.D. in Pharmaceutical Chemistry from Hamdard University, New Delhi, India

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Biography

Dr. Mymoona Akhter is currently working as Assistant Professor at Jamia Hamdard New Delhi, India. She obtained her PhD in Pharmaceutical Chemistry in 2005. She is member of following scientific societies, Indian Pharmaceutical Association, All India Pharmaceutical Teachers Association, Chemical Research Society of India, Indian Society for Analytical Scientist, Indian National Congress, and Society of Pharmaceutical Education & Research. She also supervised 7 doctoral thesis, 10 M. Pharm students, and 8 M. tech students. She has published 37 articles in journals contributed as author/co-author. She also organized more than 9 activities.

Area of Interest:

Chemistry
100%
Pharmaceutical Sciences
62%
Medicinal Chemistry
90%
Drug Design
75%
Biochemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Singh, A.P., J. Singh, R. Sharma, M. Akhter and P.K. Mishra et al., 2018. Biochemical characterization of unusual cysteine protease of P. falciparum, metacaspase-2 (MCA-2). Mol. Biochem. Parasitol., 220: 28-41.
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  2. Sharma, K., A. Shrivastava, R.N. Mehra, G.S. Deora, M.M. Alam, M.S. Zaman and M. Akhter, 2018. Synthesis of novel benzimidazole acrylonitriles for inhibition of Plasmodium falciparum growth by dual target inhibition. Arch. Pharm., Vol. 351, No. 1. 10.1002/ardp.201700251.
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  3. Kumar, G., O. Tanwar, J. Kumar, M. Akhter and S. Sharma et al., 2018. Pyrazole-pyrazoline as promising novel antimalarial agents: A mechanistic study. Eur. J. Med. Chem., 149: 139-147.
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  4. Akhter, M., M. Tasleem, M.M. Alam and S. Ali, 2017. In silico approach for bioremediation of arsenic by structure prediction and docking studies of arsenite oxidase from Pseudomonas stutzeri TS44. Int. Biodeterior. Biodegrad., 122: 82-91.
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  5. Verma, G., M.F. Khan, W. Akhtar, M.M. Alam and M. Akhter et al., 2016. Pharmacophore modeling, 3D-QSAR, docking and ADME prediction of quinazoline based EGFR inhibitors. Arabian J. Chem., (In Press). 10.1016/j.arabjc.2016.09.019.
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  6. Shrivastava, A., J. Kumar, M. Akhter and M. Shaqiquzamman, 2016. In-silico assessment of various PDB entries of PFLDH enzyme for their use in SBDD. Chem. Inform., Vol. 2, No. 1. 10.21767/2470-6973.100016.
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  7. Sharma, S., S. Paliwal, S. Singh and M. Akhter, 2016. Molecular modeling of viral nucleocapsid protein Zn fingers modulators. Indian J. Biochem. Biophys., 53: 24-38.
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  8. Pandey, A.K., S. Sharma, M. Pandey, M.M. Alam, M. Shaquiquzzaman and M. Akhter, 2016. 4, 5-Dihydrooxazole-pyrazoline hybrids: Synthesis and their evaluation as potential antimalarial agents. Eur. J. Med. Chem., 123: 476-486.
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  9. Khan, M.F., G. Verma, W. Akhtar, M. Shaquiquzzaman, M. Akhter, M.A. Rizvi and M.M. Alam, 2016. Pharmacophore modeling, 3D-QSAR, docking study and ADME prediction of acyl 1,3,4-thiadiazole amides and sulfonamides as antitubulin agents. Arabian J. Chem., (In Press). 10.1016/j.arabjc.2016.11.004.
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  10. Saha, R., O. Tanwar, M.M. Alam, M.S. Zaman, S.A. Khan and M. Akhter, 2015. Pharmacophore based virtual screening, synthesis and SAR of novel inhibitors of Mycobacterium sulfotransferase. Bioorganic Med. Chem. Lett., 25: 701-707.
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  11. Saha, R., M.M. Alam and M. Akhter, 2015. Novel hybrid-pyrrole derivatives: Their synthesis, antitubercular evaluation and docking studies. RSC Adv., 5: 12807-12820.
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  12. Marella, A., M. Akhter, M.S. Zaman, O. Tanwar, G. Verma and M.M. Alam, 2015. Synthesis, 3D QSAR and docking studies of pyrimidine nitrile pyrazolone: A novel class of hybrid antimalarial agents. Med. Chem. Res., 24: 1018-1037.
  13. Akhter, M., R. Saha, O. Tanwar, M.M. Alam and M.S. Zaman, 2015. Synthesis and antimalarial activity of quinoline-substituted furanone derivatives and their identification as selective falcipain-2 inhibitors. Med. Chem. Res., 24: 879-890.
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  14. Tanwar, O., L. Tanwar, M. Shaquiquzzaman, M.M. Alam and M. Akhter, 2014. Structure based virtual screening of MDPI database: Discovery of structurally diverse and novel DPP-IV inhibitors. Bioorganic Med. Chem. Lett., 24: 3447-3451.
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  15. Tanwar, O., G.S. Deora, L. Tanwar, G. Kumar and S. Janardhan et al., 2014. Novel hydrazine derivatives as selective DPP-IV inhibitors: Findings from virtual screening and validation through molecular dynamics simulations. J. Mol. Modeling. 10.1007/s00894-014-2118-7.
    CrossRef  |  
  16. Marella, A., M. Shaquiquzzaman, M. Akhter, G. Verma and M.M. Alam, 2014. Novel pyrazole-pyrazoline hybrids endowed with thioamide as antimalarial agents: Their synthesis and 3D-QSAR studies. J. Enzyme Inhibition Med. Chem., 30: 597-606.
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  17. Marella, A., M. Akhtar and M. Shaquiquzzaman, 2014. Synthesis and in-vitro antimalarial evaluation of pyrazoline: A new antimalarial scaffold. J. Pharm. Res., 8: 77-80.
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  18. Husain, A., P. Ahuja, M. Shaharyar, A. Ahmad and I.A.I. Mkhalid et al., 2014. Synthesis, biological activities and pharmacokinetics studies of a mutual prodrug of aceclofenac and paracetamol. Med. Chem. Res., 23: 1077-1083.
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  19. Akhter, M., K. Sharma, M.M. Alam, M.S. Zaman, A. Husain, S. Ali and S.A. Khan, 2014. Structure assessment analysis of core domain of seven protein data bank entries of HIV-1 protease using different in-silico techniques. Curr. Enzyme Inhibition, 10: 98-104.
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  20. Tanwar, O., A. Marella, S. Srivastav, M.M. Alam and M. Akhter, 2013. Pharmacophore model generation and 3D-QSAR analysis of N-acyl and N-aroylpyrazolines for enzymatic and cellular B-Raf kinase inhibition. Med. Chem. Res., 22: 2174-2187.
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  21. Saha, R., O. Tanwar, A. Marella, M.M. Alam and M. Akhter, 2013. Recent updates on biological activities of oxadiazoles. Mini Rev. Med. Chem., 13: 1027-1046.
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  22. Marella, A., O.P. Tanwar, R. Saha, M.R. Ali and S. Srivastava et al., 2013. Quinoline: A versatile heterocyclic. Saudi Pharm. J., 21: 1-12.
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  23. Marella, A., O. Tanwar, R. Saha, M.M. Alam, M.S. Zaman and M. Akhter, 2013. 3D quantitative structure-activity relationship for quinoline, benzimidazole and benzofuran-based analogs as phosphodiesterases IV (PDE-IV) inhibitors. Med. Chem. Res., 22: 5153-5166.
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  24. Kumar, J., G. Chawla, M. Akhtar, K. Sahu, V. Rathore and S. Sahu, 2013. Design, synthesis and pharmacological evaluation of some novel derivatives of 1-{[3-(furan-2-yl)-5-phenyl-4, 5-dihydro-1, 2-oxazol-4-yl] methyl}-4-methyl piperazine. Arabian J. Chem. 10.1016/j.arabjc.2013.04.027.
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  25. Kumar, J., G. Chawla, H. Gupta, M. Akhtar, O. Prakash Tanwar and M. Bhowmik, 2013. Synthesis and neuropharmacological evaluation of some new isoxazoline derivatives as antidepressant and anti-anxiety agents. Afr. J. Pharm. Pharmacol., 7: 1523-1530.
  26. Alam, M.M., A. Marella, M. Akhtar, A. Husain and M.S. Yar et al., 2013. Microwave assisted one pot synthesis of some pyrazole derivatives as safer anti-inflammatory and analgesic agents. Acta Poloniae Pharm. Drug Res., 70: 435-441.
  27. Akther, N., A.S. Shawl, S. Sultana, B.K. Chandan and M. Akhter, 2013. Hepatoprotective activity of Marrubium vulgare against paracetamol induced toxicity. J. Pharm. Res., 7: 565-570.
    CrossRef  |  
  28. Tanwar, O., R Saha, M.M. Alam and M. Akhtar, 2012. 3D-QSAR of amino-substituted pyrido [3,2B] pyrazinones as PDE-5 inhibitors. Med. Chem. Res., 21: 202-211.
    CrossRef  |  
  29. Rathish, I.G., K. Javed, S. Ahmad, S. Bano and M.S. Alam et al., 2012. Synthesis and evaluation of anticancer activity of some novel 6-aryl-2-(p-sulfamylphenyl)-pyridazin-3(2H)-ones. Eur. J. Med. Chem., 49: 304-309 Eur. J. Med. Chem., 49: 304-309.
    CrossRef  |  
  30. Ali, M.R., A. Marella, M.T. Alam, R. Naz and M. Akhter et al., 2012. Review of biological activities of hydrazones. Indo J. Pharm., 23: 193-202.
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  31. Alam, M.M., M. Akhter, A. Husain, A. Marella and O.P. Tanwar, 2012. Anti-inflammatory and antimicrobial activity of 4,5-dihydropyrimidine-5- carbonitrile derivatives: Their synthesis and spectral elucidation. Acta Pol. Pharm. Drug Res., 6: 1077-1085.
  32. Akhter, M. and P.V. Bharatam, 2012. 3D-QSAR and molecular docking studies on3-Anilino-4-arylmaleimide derivatives as glycogen synthase kinase-3β inhibitors. Chem. Biol. Drug Des., 79: 560-571.
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  33. Kataria, A.K., S.A. Khan, M.M. Alam, A. Husain and M. Akhtar et al., 2011. Synthesis of some new 2-(substituted-phenyl)-5-(N,N-diphenylaminomethyl)-1,3,4-oxadiazoles: A safer anti-inflammatory and analgesic agents. Acta Pol. Pharm. Drug Res., 68: 381-386.
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  34. Hasan, H., M. Akhter, W. Akhter, I. Ali and M. Zaheen, 2011. Design and synthesis of novel N-substituted-3-chloro-2-azetidinone derivatives as potential anticonvulsant agents. Med. Chem. Res., 20: 1357-1363.
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  35. Alam, M.M., D.P. Sarkar, O. Alam, A. Husain and A. Marella et al., 2011. Search for new pharmacophore as antimalarial agent: Synthesis and antimalarial activity of some 2(3h)-furanones bearing quinoline moiety. Acta. Pol. Pharm., 68: 231-236.
    Direct Link  |  
  36. Alam, M.M., D.P. Sarkar, A. Husain, A. Marella and M.S. Zaman et al., 2011. Synthesis of quinoline-attached furan-2(3H)-ones having anti-inflammatory and antibacterial properties with reduced gastro-intestinal toxicity and lipid peroxidation. J. Serb. Chem. Soc., 76: 1617-1626.
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  37. Akhter, M., S. Habibullah, S.M. Hasan, M.M. Alam, N. Akhter and M. Shaquiquzzaman, 2011. Synthesis of some new 3,4-dihydro-2H-1,3-benzoxazines under microwave irradiation in solvent-free conditions and their biological activity. Med. Chem. Res., 20: 1147-1153.
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  38. Akhter, M., N. Akhter, M.M. Alam, M.S. Zaman, R. Saha and A. Kumar, 2011. Synthesis and biological evaluation of 2,5-disubstituted 1,3,4-oxadiazole derivatives with both COX and LOX inhibitory activity. J. Enz. In. Med. Chem., 26: 767-776.
  39. Akhter, M., A. Husain, N. Akhter and M.S.Y. Khan, 2011. Synthesis, anti-inflammatory and antimicrobial activity of some new 1-(3-Phenyl-3,4-Dihydro 2H-1,3-Benzoxazin-6-yl)-ethanone derivatives. Ind. J. Pharm. Sci., 73: 101-104.
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  40. Husain, A., A. Ahmad, M. Mujeeb and M. Akhter, 2010. New amides of sulphonamides: Synthesis and biological evaluation. J. Chilean Chem. Soc., 55: 74-77.
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  41. Hasan, S.M., M.M. Alam, A. Husain, S. Khanna, M. Akhtar and M.S. Zaman, 2009. Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: Anti-inflammatory-analgesic and antimicrobial. Eur. J. Med. Chem., 44: 4896-4903.
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  42. Akhter, M., A. Husain, B. Azad and M. Ajmal, 2009. Aroylpropionic acid based 2,5-disubstituted-1,3,4-oxadiazoles: Synthesis and their anti-inflammatory and analgesic activities. Eur. J. Med. Chem., 44: 2372-2378.
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  43. Khan, M.S.Y., M. Akhtar and A. Husain, 2006. Synthesis, biological evaluation and kinetic studies of glyceride prodrugs of biphenyl acetic acid. Ind. J. Chem., 45: 1014-1019.
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  44. Khan, M.S.Y. and M. Akhter, 2005. Synthesis, pharmacological activity and hydrolytic behavior of glyceride prodrugs of ibuprofen. Eur. J. Med. Chem., 40: 371-376.
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  45. Khan, M.S.Y. and M. Akhter, 2005. Glyceride derivatives as potential prodrugs: Synthesis, biological activity and kinetic studies of glyceride derivatives of mefenamic acid. Die Pharmazie-Int. J. Pharm. Sci., 60: 110-114.
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  46. Khan, M.S.Y. and M. Akhtar, 2004. Synthesis, biological evaluation and kinetic studies of glyceride prodrugs of diclofenac. Ind. J. Exp. Biol., 42: 1066-1072.
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  47. Khan, M.S.Y. and M. Akhtar, 2003. Synthesis of some new 2,5-disubstituted 1,3,4-oxadiazole derivatives and their biological activity. Indian J. Chem., 42: 900-904.
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  48. Khan, M.S.Y., A. Husain, S.M. Hasan and M. Akhter, 2002. Synthesis of some new prodrugs of sulphonamides and studies on their antimicrobial and anti-inflammatory action. Scientia Pharmaceutica, 70: 277-286.
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