Dr. Esra Kupeli Akkol
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Dr. Esra Kupeli Akkol

Professor
Gazi University, Turkiye

Highest Degree
Ph.D. in Pharmacognosy from Gazi University, Ankara, Turkiye

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Area of Interest:

Pharmacology and Toxicology
100%
Analytical Pharmacognosy
62%
Anti Inflammatory
90%
Phytochemistry
75%
Medicinal Plant
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Tumen, I., E.K. Akkol, H. Tastan, I. Suntar and M. Kurtca, 2018. Research on the antioxidant, wound healing and anti-inflammatory activities and the phytochemical composition of maritime pine (Pinus pinaster Ait). J. Ethnopharmacol., 211: 235-246.
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  2. Ozbilgin, S., E.K. Akkol, B.E. Oz, M. Ilhan and G. Saltan et al., 2018. In vivo activity assessment of some Tanacetum species used as traditional wound healer along with identification of the phytochemical profile by a new validated HPLC method. Iran. J. Basic Med. Sci., 21: 145-152.
  3. Oz, B.E., G.S. Iscan, E.K. Akkol, I. Suntar and O.B. Acikara, 2018. Isoflavonoids as wound healing agents from Ononidis radix. J. Ethnopharmacol., 211: 384-393.
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  4. Tumen, I., F.T. Guragac, H. Keles, M. Reunanen and E.K. Akkol, 2017. Characterization and wound repair potential of essential oil Eucalyptus globules Labill. Fresenius Environ. Bull., 26: 6390-6399.
  5. Tumen, I., E.K. Akkol, I. Suntar, G. Erbey and M. Kurtca et al., 2017. Evaluation of the wound healing and anti-inflammatory activities and phytochemical analysis of Myrtus communis L. Fresenius Environ. Bull., 26: 4420-4428.
  6. Suntar, I., E.K. Akkol and M. Ilhan, 2017. Myrtus communis. In: Association of Pharmacognosy and Phytotherapy Monographs, Demirezer, O., T. Ersoz, I. Saraco lu, B. Sener, A. Koro lu and F.N. Yalcn (Eds.). Vol. 3, Akademisyen Publishing House, Ankara, Turkey, pp: 793-802.
  7. Oz, B.E., G.S. Iscan, E.K. Akkol, I. Suntar, H. Keles and O.B. Acikara, 2017. Wound healing and anti-inflammatory activity of some Ononis taxons. Biomed. Pharmacother., 91: 1096-1105.
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  8. Iscan, G.S., A. Koroglu, E. Akkol, O.B. Acikara and A. Gokbulut et al., 2017. Turkish pharmacopoeia new monographs-1: Gilaburu fruit (Viburni fructus). J. Turk. Pharm., 2: 135-145.
  9. Ilhan, M. and E.K. Akkol, 2017. Acorus calamus. In: Association of Pharmacognosy and Phytotherapy Monographs, Demirezer, O., T. Ersoz, I. Saraco lu, B. Sener, A. Koro lu and F.N. Yalcn (Eds.). Vol. 3, Akademisyen Publishing House, Ankara, Turkey, pp: 1-12.
  10. Guragac, F.T., M. Ilhan, I. Tumen and E.K. Akkol, 2017. Insights into research on the anti-inflammatory and antinociceptive activities of Scandix iberica Bieb. Fresenius Environ. Bull., 26: 5125-5135.
  11. Ceylantekin, Y., E.K. Akkol and V. Ozdemir, 2017. The effects of different extracts of Glycine max (L.) Merr. on primordial, primary and secondary follicles. Eurasian J. Vet. Sci., 33: 1-7.
  12. Akkol, E.K., I. Suntar and M. Ilhan, 2017. Hibiscus esculentus. In: Association of Pharmacognosy and Phytotherapy Monographs, Demirezer, O., T. Ersoz, I. Saraco lu, B. Sener, A. Koro lu and F.N. Yalcn (Eds.). Vol. 3, Akademisyen Publishing House, Ankara, Turkey, pp: 567-572.
  13. Tosun, A., I. Suntar, H. Keles, H.O. Kiremit, Y. Asakawa and E.K. Akkol, 2016. Wound healing potential of selected liverworts growing in Turkey. Turk. J. Pharm. Sci., 13: 285-291.
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  14. Suntar, I., O. Oyardi, E.K. Akkol and B. Ozcelik, 2016. Antimicrobial effect of extracs from Hypericum perforatum L. against oral bacteria and biofilm formation. Pharm. Biol., 54: 1065-1070.
  15. Suntar, I., M.A. Demirel and E.K. Akkol, 2016. Complementary Therapy with Traditional Herbal Medicines in Obstetric and Gynecologic Disorders-II: Menstrual Cycle and its Disorders, Reproductive Performance and Menopause. In: Traditional and Folk Herbal Medicine: Recent Researches, Gupta, V.K. (Ed.). Daya Publishing House, New Delhi, pp: 37-96.
  16. Saltan, G., I. Suntar, S. Ozbilgin, M. Ilhan and M.A. Demirel et al., 2016. Viburnum opulus L.: A remedy for the treatment of endometriosis demonstrated by rat model of surgically-induced endometriosis. J. Ethnopharmacol., 193: 450-455.
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  17. Orhan, I.E., F. Gulyurdu, E.K. Akkol, F.S. Senol, S.A. Anul and I.I. Tatli, 2016. Anticholinesterase, antioxidant, analgesic and anti-inflammatory activity assessment of Xeranthemum annuum L. and isolation of two cyanogenic compounds. Pharm. Biol., 54: 2643-2651.
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  18. Kuranel, E., E.K. Akkol, I. Suntar, S. Gursoy, H. Keles and G. Aktay, 2016. Investigating biological activity potential of Plantago lanceolata L. in healing of skin wounds by a preclinical research. Turk. J. Pharm. Sci., 13: 135-144.
  19. Kucukkurt, I., E.K. Akkol, F. Karabag, S. Ince, I. Suntar, A. Eryavuz and N.B. Sozbilir, 2016. Determination of the regulatory properties of Yucca schidigera extracts on the biochemical parameters and plasma hormone levels associated with obesity. Rev. Brasil. Farmacog., 26: 246-250.
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  20. Kucukboyaci, N., E.K. Akkol, I. Suntar and I. Calis, 2016. In vivo anti-inflammatory and antinociceptive activities of the extracts and chemical constituents of an endemic Turkish plant, Salsola grandis. Records Nat. Prod., 10: 369-379.
  21. Kozan, E., E.K. Akkol and I. Suntar, 2016. Potential anthelmintic activity of Pelargonium endlicherianum Fenzl. J. Ethnopharmacol., 187: 183-186.
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  22. Ilhan, M., I. Suntar, M.A. Demirel, E. Yesilada, H. Keles and E.K. Akkol, 2016. A mixture of St. John's wort and sea buckthorn oils regresses endometriotic implants and affects the levels of inflammatory mediators in peritoneal fluid of the rat: A surgically induced endometriosis model. Taiwanese J. Obstet. Gynecol., 55: 786-790.
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  23. Ilhan, M., G. Zengin, E.K. Akkol, A. Aktumsek and I. Suntar, 2016. The importance of Asphodeline species on enzyme inhibition: Anti-elastase, anti-hyaluronidase and anti-collagenase potential. Turk. J. Pharm. Sci., 13: 323-327.
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  24. Ergene, O.Z.B., M. Ilhan, S. Ozbilgin, E.K. Akkol and O.B. Acikara et al., 2016. Effects of Alchemilla mollis and Alchemilla persica on the wound healing process. Bangladesh J. Pharmacol., 11: 577-584.
  25. Erfidan, M.A., E. Akkol, A. Sevimli and T. Civelek, 2016. Effects of pomegranate (Punica granatum L.) on paracetamol induced acute hepatic damage in mice. Kocatepe Vet. J., 9: 273-280.
  26. Demirel, M.A., M. Ilhan, I. Suntar, H. Keles and E.K. Akkol, 2016. Activity of Corylus avellana seed oil in letrozole-induced polycystic ovary syndrome model in rats. Revista Brasileira de Farmacognosia, 26: 83-88.
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  27. Demirel, M.A., I. Suntar and E.K. Akkol, 2016. Complementary Therapy with Traditional Herbal Medicines in Obstetric and Gynecologic Disorders-I: Abortion, Pseudopregnancy, Lactation and Mastitis. In: Traditional and Folk Herbal Medicine: Recent Researches, Gupta, V.K. (Ed.). Daya Publishing House, New Delhi, pp: 1-36.
  28. Berk, B., C. Bender, E.K. Akkol and E. Yesilada, 2016. Design and synthesis of stable N-[2-(aryl/heteroaryl substituted) ethyl]propanamide derivatives of (S)-ketoprofen and (S)-ibuprofen as non-ulcerogenic anti-inflammatory and analgesic agents. ACTA Pharm. Sci., 54: 65-80.
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  29. Altınyay, C., I. Suntar, L. Altun, H. Keles and E.K. Akkol, 2016. Phytochemical and biological studies on Alnus glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens leaves. J. Ethnopharmacol., 192: 148-160.
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  30. Akkol, E.K., I. Suntar and M.A. Demirel, 2016. Complementary Therapy with Traditional Herbal Medicines in Obstetric and Gynecologic Disorders-III: Leucorrhea, Endometriosis, Uterine Fibroid, Ovarian Cyst and Gynecological Cancers. In: Traditional and Folk Herbal Medicine: Recent Researches, Gupta, V.K. (Ed.). Daya Publishing House, New Delhi, pp: 97-166.
  31. Suntar, I., E.K. Akkol, T.M. Gonenc, T.F. Erdogan and B. Kivcak, 2015. Scientific assessment of the anti-inflammatory potential of Campanula lyarata Lam. subsp. lyrata, a Turkish folk remedy. Turk. J. Pharm. Sci., 12: 157-168.
  32. Koklu, A.H.K., E.K. Akkol and D.A.U. Cankal, 2015. Biochemical and assessment of effect of l-carnitine on oral mucosal wounds. Clin. Oral Invest., 19: 1101-1106.
  33. Ilhan, M., I.E. Bolat, I. Suntar, H.K. Koklu, D.A.U. Cankal, H. Keles and E.K. Akkol, 2015. Topical application of olive oil macerate of Momordica charantia L. promotes healing of excisional and incisional wounds in rat buccal mucosa. Arch. Oral Biol., 60: 1708-1713.
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  34. Ilhan, M., I. Suntar and E.K. Akkol, 2015. An Update on Plant Originated Remedies for the Medication of Hyperlipidemia. In: Therapeutic Medicinal Plants: From Lab to the Market, Duarte, M.C.T. and M. Rai (Eds.). CRC Press, USA., ISBN: 9781482254037, pp: 353-374.
  35. Erdogan, T.F., E.K. Akkol, I. Suntar, T.M. Gonenc and B. Kivcak, 2015. Fatty acid compositions and anti-inflammatory activities of Tripleurospermum parviflorum (Willd.) Pobed. and Tripleurospermum tenuifolium (Kit.). Records Nat. Prod., 9: 394-403.
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  36. Akkol, E.k., I. Suntar, M. Ilhan and E. Aras, 2015. In vitro enzyme inhibitory effects of Rubus sanctus Schreber and its active metabolite as a function of wound healing activity. J. Herbal Med., 5: 207-210.
  37. Akkol, E.K., M.A. Demirel, O.B. Acikara, I. Suntar and B. Ergene et al., 2015. Phytochemical analyses and effects of Alchemilla mollis (Buser) Rothm. and Alchemilla persica Rothm. in rat endometriosis model. Arch. Gynecol. Obstet., 292: 619-628.
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  38. Akkol, E.K., M. Ilhan, M.A. Demirel, H. Keles, I. Tumen and I. Suntar, 2015. Thuja occidentalis L. and its active compound, α-thujone: Promising effects in the treatment of polycystic ovary syndrome without inducing osteoporosis. J. Ethnopharmacol., 168: 25-30.
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  39. Akkol, E.K., I. Suntar, H. Keles, E. Sezik and G. Gurler, 2015. Bioassay-guided isolation and characterization of wound healer compounds from Morus nigra L. (Moraceae). Records Nat. Prod., 9: 484-495.
  40. Suntar, I., H. Keles, A. Tosun and E.K. Akkol, 2014. Comparative pharmacological investigation on the wound healing effects of the frequently used essential oils. J. Essential Oil Res., 26: 41-49.
  41. Suntar, I., E.K. Akkol, H. Keles, E. Yesilada, S. Sarker and T. Baykal, 2014. Daphne oleoides Schreber ssp. oleoides exhibits potent wound healing effect: Isolation of the active components and elucidation of the activity mechanism. Records Nat. Prod., 8: 93-109.
    PubMed  |  
  42. Ilhan, M., B. Ergene, I. Suntar, S. Ozbilgin and G.S. Citoglu et al., 2014. Preclinical evaluation of anti-urolithiatic activity of Viburnum opulus on sodium oxalate-induced urolithiasis rat model. Evid. Based Complement. Altern. Med., Vol. 2014. 10.1155/2014/578103.
    CrossRef  |  
  43. Gonenc, T.M., E.K. Akkol, I. Suntar, T.F. Erdogan and B. Kivcak, 2014. Fatty acid composition and preclinical resarches on Anthemis wiedemanniana Fisch. & Mey.: Discovery of a new anti-inflammatory agent. Pharmacogn. Magaz., 10: 53-60.
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  44. Demirel, M.A., I. Suntar, M. Ilhan, H. Keles and E.K. Akkol, 2014. Experimental endometriosis remission in rats treated with Achillea biebersteinii Afan.: Histopathological evaluation and determination of cytokine levels. Eur. J. Obstet. Gynecol. Reprod. Biol., 175: 172-177.
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  45. Bahadir-Acikara, O., E. Kupeli-Akkol, I. Suntar, B. Ergene, G. Saltan-Citoglu and T. Coban, 2014. Assessment of anti-inflammatory and free radical scavenger activities of selected Scorzonera Species and determination of active components. Int. J. Pharmacogn. Phytochem. Res., 6: 59-65.
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  46. Tumen, I., I. Suntar, F.J. Eller, H. Keles and E.K. Akkol, 2013. Topical wound-healing effects and phytochemical composition of heartwood essential oils ofJuniperus virginiana L., Juniperus occidentalis Hook. and Juniperus ashei J. Buchholz. J. Med. Food, 16: 48-55.
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  47. Tosun, A., E.K. Akkol, I. Suntar, H.O. Kiremit and Y. Asakawa, 2013. Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models. Pharm. Biol., 51: 1008-1013.
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  48. Tiryaki, D., M. Sukuroglu, D.S. Dogruer, E. Akkol, S. Ozgen and M.F. Sahin, 2013. Synthesis of some new 2,6-disubstituted-3(2H)-pyridazinone derivatives and investigation of their analgesic, anti-inflammatory and antimicrobial activities. Med. Chem. Res., 22: 2553-2560.
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  49. Suntar, I., E.K. Akkol, H. Keles, E. Yesilada and S.D. Sarker, 2013. Exploration of the wound healing potential of Helichrysum graveolens (Bieb.) Sweet: Isolation of apigenin as an active component. J. Ethnopharmacol., 149: 103-110.
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  50. Suntar, I. and E.K. Akkol, 2013. Importance of Cichorium species: Insight into the Wide Range of Biological Activities and Phytochemical Ingredients. In: Bioactive Phytochemicals: Perspectives for Modern Medicine, Gupta, V.K. (Ed.). M/S. Daya Publication House, New Delhi, pp: 327-354.
  51. Suntar, I. and E.K. Akkol, 2013. Beneficial effects of plant sources on the treatment of osteoporosis. Curr. Drug Targets, 14: 1611-1618.
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  52. Sukuroglu, M., C. Yamali, D. Tiryaki, F.K. Onurdag, E. Akkol and D.S. Dogruer, 2013. Synthesis of some new 3(2H)-pyridazinone derivatives and evaluation of their analgesic-anti-inflammatory and antimicrobial activities. Lett. Drug Des. Discov., 10: 507-514.
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  53. Renda, G., F.N. Yalcin, E. Nemutlu, E.K. Akkol and I. Suntar et al., 2013. Comparative assessment of dermal wound healing potentials of various Trifolium L. extracts and determination of their isoflavone contents as potential active ingredients. J. Ethnopharmacol., 148: 423-432.
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  54. Bruno, M., B. Trucchi, B. Burlando, E. Ranzato and S. Martinotti et al., 2013. (+)-Usnic acid enamines with remarkable cicatrizing properties. Bioorg. Med. Chem., 21: 1834-1843.
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  55. Akkol, E.K., I. Suntar and E. Yesilada, 2013. Phytochemical and Biological Activity Studies on the Genus Berberis L.: A Potential Target for Novel Drug Discovery. In: Phytoconstituents and Biochemical Processes, Govil, J.N. and L. Tiwari (Eds.). Studium Press, USA., ISBN-13: 978-1933699257, pp: 223-251.
  56. Akkol, E.K. and I. Suntar, 2013. Potential Sources for the Discovery of Novel Wound Healing Remedies from Turkish Traditional Medicinal Plants: An Overview. In: Phytoconstituents and Biochemical Processes, Govil, J.N. and L. Tiwari (Eds.). Studium Press, USA., ISBN-13: 978-1933699257, pp: 33-72.
  57. Tumen, I., I. Suntar, H. Keles and E.K. Akkol, 2012. A therapeutic approach for wound healing by using essential oils of Cupressus and Juniperus species growing in Turkey. Evid. Based Complement. Altern. Med., Vol. 2012. 10.1155/2012/728281.
    CrossRef  |  
  58. Sutar, I., O.B. Acikara, G.S. Citoglu, H. Keles, B. Ergene and E.K. Akkol, 2012. In vivo and in vitro evaluation of the therapeutic potential of some Turkish Scorzonera species as wound healing agent. Curr. Pharm. Des., 18: 1421-1433.
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  59. Suntar, I., E.K. Akkol, L. Nahar and S.D. Sarker, 2012. Wound healing and antioxidant properties: Do they coexist in plants? Free Radicals Antioxid., 2: 1-7.
    CrossRef  |  
  60. Suntar, I., E.K. Akkol, H. Keles, E. Yesilada, S.D. Sarker, R. Arroo and T. Baykal, 2012. Efficacy of Daphne oleoides subsp. kurdica used for wound healing: Identification of active compounds through bioassay guided isolation technique. J. Ethnopharmacol., 141: 1058-1070.
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  61. Suntar, I., E.K. Akkol, H. Keles, E. Yesilada, S.D. Sarker and T. Baykal, 2012. Comparative evaluation of traditional prescriptions from Cichorium intybus L. for wound healing: Stepwise isolation of an active component by in vivo bioassay and its mode of activity. J. Ethnopharmacol., 143: 299-309.
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  62. Suntar, I., E.K. Akkol and T. Baykal, 2012. Chemical Constituents and Biological Activities of Daphne Genus: An Overview. In: Phytoconstituents and Physiological Processes, Govil, J.N., G. Kaushik and N. Rai (Eds.). Studium Press, USA., pp: 158-189.
  63. Sintar, I., I. Tumen, O. Ustun, H. Keles and E.K. Akkol, 2012. Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models. J. Ethnopharmacol., 139: 533-540.
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  64. Orhan, N., E. Akkol and F. Ergun, 2012. Evaluation of antiinflammatory and antinociceptive effects of some Juniperus species growing in Turkey. Turk. J. Biol., 36: 719-726.
    Direct Link  |  
  65. Keles, H., S. Ince, I. Kucukkurt, I.I. Tatli, E.K. Akkol, C. Kahraman and H.H. Demirel, 2012. The effects of Feijoa sellowiana fruits on the antioxidant defense system, lipid peroxidation and tissue morphology in rats. Pharm. Biol., 50: 318-325.
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  66. Guvenc, A., E.K. Akkol, M.M. Hurkul, I. Suntar and H. Keles, 2012. Wound healing and anti-inflammatory activities of the Michauxia L’Hérit (Campanulaceae) species native to Turkey. J. Ethnopharmacol., 139: 401-408.
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  67. Guvenc, A., E.K. Akkol, I. Suntar, H. Keles, S. Yildiz and I. Calis, 2012. Biological activities of Pseudevernia furfuracea (L.) Zopf extracts and isolation of the active compounds. J. Ethnopharmacol., 144: 726-734.
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  68. Akkol, E.K., O.B. Acıkara, I. Sintar, B. Ergene and G.S. Citoglu, 2012. Ethnopharmacological evaluation of some Scorzonera species: In vivo anti-inflammatory and antinociceptive effects. J. Ethnopharmacol., 140: 261-270.
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  69. Akkol, E.K., I.E. Orhan and E. Yesilada, 2012. Anticholinesterase and antioxidant effects of the ethanol extract, ethanol fractions and isolated flavonoids from Cistus laurifolius L. leaves. Food Chem., 131: 626-631.
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  70. Akkol, E.K., I. Suntar, T.F. Erdogan, H. Keles, T.M. Gonenc and B. Kivcak, 2012. Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: A comparative study. J. Ethnopharmacol., 139: 478-484.
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  71. Akkol, E.K., H. Kirmizibekmez, N. Kucukboyaci, A.C. Goren and E. Yesilada, 2012. Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures. J. Ethnopharmacol., 139: 527-532.
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  72. Tumen, I., E.K. Akkol, I. Suntar and H. Keles, 2011. Wound repair and anti-inflammatory potential of essential oils from cones of Pinaceae: Preclinical experimental research in animal models. J. Ethnopharmacol., 137: 1215-1220.
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  73. Suntar, I., U. Koca, H. Keles and E.K. Akkol, 2011. Wound healing activity of rubus sanctus schreber (Rosaceae): Preclinical study in animal models. Evid. Based Complemen. Altern. Med., Vol. 2011, 10.1093/ecam/nep137.
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  74. Suntar, I., E.K. Akkol, H. Keles, A. Oktem, K.H.C. Baser and E. Yesilada, 2011. A novel wound healing ointment: A formulation of Hypericum perforatum oil and sage and oregano essential oils based on traditional Turkish knowledge. J. Ethnopharmacol., 134: 89-96.
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  75. Suntar, I., E.K. Akkol, F.S. Senol, H. Keles and I.E. Orhan, 2011. Investigating wound healing, tyrosinase inhibitory and antioxidant activities of the ethanol extracts of Salvia cryptantha and Salvia cyanescens using in vivo and in vitro experimental models. J. Ethnopharmacol., 135: 71-77.
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  76. Suntar, I., A. Baldemir, M. Coskun, H. Keles and E.K. Akkol, 2011. Wound healing acceleration effect of endemic Ononis species growing in Turkey. J. Ethnopharmacol., 135: 63-70.
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  77. Orhan, I.E., I.P. Suntar and E.K. Akkol, 2011. In vitro neuroprotective effects of the leaf and fruit extracts of Juglans regia L.(walnut) through enzymes linked to Alzheimer's disease and antioxidant activity. Int. J. Food Sci. Nutr., 62: 781-786.
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  78. Orhan, I.E. and E.K. Akkol, 2011. Estimation of neuroprotective effects of Laurocerasus officinalis Roem.(cherry laurel) by in vitro methods. Food Res. Int., 44: 818-822.
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  79. Kozan, E., I.T. Cankaya, C. Kahraman, E.K. Akkol and Z. Akdemir, 2011. The in vivo anthelmintic efficacy of some Verbascum species growing in Turkey. Exp. Parasitol., 129: 211-214.
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  80. Koca, U., I. Suntar, E.K. Akkol, D. Yilmazer and M. Alper, 2011. Wound repair potential of Olea europaea L. leaf extracts revealed by in vivo experimental models and comparative evaluation of the extracts' antioxidant activity. J. Med. Food, 14: 140-146.
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  81. Koca, U., E.K. Akkol and N. Sekeroglu, 2011. Evaluation of in vivo and in vitro biological activities of different extracts from Cuscuta arvensis Beyr. (Convolvulaceae). Nat. Prod. Commun., 6: 1433-1436.
  82. Akkol, E.K., U. Koca, I. Pesin and D. Yilmazer, 2011. Evaluation of the wound healing potential of Achillea biebersteinii Afan. (Asteraceae) by in vivo excision and incision models. Evidence-Based Complement. Altern. Med. 10.1093/ecam/nep039.
    CrossRef  |  
  83. Akkol, E.K., O.B. Acikara, I. Suntar, G.S. Citoglu, H. Keles and B. Ergene, 2011. Enhancement of wound healing by topical application of Scorzonera species: Determination of the constituents by HPLC with new validated reverse phase method. J. Ethnopharmacol., 137: 1018-1027.
    CrossRef  |  Direct Link  |  
  84. Akkol, E.K., I. Suntar, I.E. Orhan, H. Keles, A. Kan and G. Coksari, 2011. Assessment of dermal wound healing and in vitro antioxidant properties of Avena sativa L. J. Cereal Sci., 53: 285-290.
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  85. Akkol, E.K., I. Suntar, H. Keles and E. Yesilada, 2011. The potential role of female flowers inflorescence of Typha domingensis Pers. in wound management. J. Ethnopharmacol., 133: 1027-1032.
    CrossRef  |  Direct Link  |  
  86. Akdemir, Z., C. Kahraman, I.I. Tatli, E.K. Akkol, I. Suntar and H. Keles, 2011. Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam. J. Ethnopharmacol., 136: 436-443.
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  87. Suntar, I.P., U. Koca, E.K. Akkol, D. Yilmazer and M. Alper, 2011. Assessment of wound healing activity of the aqueous extracts of Colutea cilicica Boiss. and Bal. fruits and leaves. Evid.-Based Complement. Altern. Med., Vol. 2011. 10.1093/ecam/nep190.
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  88. Suntar, I.P., E.K. Akkol, F.N. Yalcın, U. Koca, H. Keles and E. Yesilada, 2010. Wound healing potential of Sambucus ebulus L. leaves and isolation of an active component, quercetin 3-O-glucoside. J. Ethnopharmacol., 129: 106-114.
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  89. Suntar, I.P., E.K. Akkol, D. Yilmazer, T. Baykal, H. Kirmizibekmez, M. Alper and E. Yesilada, 2010. Investigations on the in vivo wound healing potential of Hypericum perforatum L. J. Ethnopharmacol., 127: 468-477.
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  90. Suntar, I.P., E.K. Akkol and T. Baykal, 2010. Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. J. Med. Food, 13: 352-356.
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  91. Suntar, I., I.I. Tatli, E.K. Akkol, H. Keles, C. Kahraman and Z. Akdemir, 2010. An ethnopharmacological study on Verbascum species: From conventional wound healing use to scientific verification. J. Ethnopharmacol., 132: 408-413.
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  92. Onkol, T., E. Banoglu, Y. Dundar, E. Kupeli and M.F. Sahin, 2010. Amide derivatives of [6-acyl-2-benzothiazolinon-3-yl] acetic acids as potential analgesic and anti-inflammatory compounds. Med. Chem. Res., 19: 11-24.
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  93. Küçükkurt, I., S. Ince, H. Keleş, E.K. Akkol, G. Avcı, E. Yeşilada and E. Bacak, 2010. Beneficial effects of Aesculus hippocastanum L. seed extract on the body's own antioxidant defense system on subacute administration. J. Ethnopharmacol., 129: 18-22.
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  94. Guvenc, A., Y. Okada, E.K. Akkol, H. Duman, T. Okuyama and I. Calıs, 2010. Investigations of anti-inflammatory, antinociceptive, antioxidant and aldose reductase inhibitory activities of phenolic compounds from Sideritis brevibracteata. Food Chem., 118: 686-692.
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  95. Gokce, M., Y. Dundar and E. Kupeli, 2010. Synthesis of (6-Substituted-3(2H)-pyridazinon-2-yl) acetic acid and (6-Substituted-3(2H)-pyridazinon-2-yl)acetamide derivatives and investigation of their analgesic and anti-inflammatory activities. FABAD J. Pharm. Sci., 35: 1-11.
  96. Avci, G., I. Kucukkurt, E.K. Akkol and E. Yesilada, 2010. Effects of escin mixture from the seeds of Aesculus hippocastanum on obesity in mice fed a high fat diet. Pharm. Biol., 48: 247-252.
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  97. Akkol, E.K., I. Orhan, M. Kartal and E. Yesilada, 2010. Bioactivity guided evaluation of anti-inflammatory and antinociceptive activities of Arceuthobium oxycedri (DC) M. Bieb. J. Ethnopharmacol., 128: 79-84.
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  98. Akkol, E.K., D.D. Orhan, I. Gurbuz and E. Yesilada, 2010. In vivo activity assessment of a honey-bee pollen mix formulation. Pharm. Biol., 48: 253-259.
    CrossRef  |  PubMed  |  Direct Link  |  
  99. Akkol, E.K. and E. Yesilada, 2010. An Anthology of the Studies on the Anti-inflammatory, Antinociceptive and Febrifuge Effects of Medicinal Plants in Turkey. In: Compherensive Bioactive Natural Products, Efficacy, Safety and Clinical Evaluation I, Gupta, V.K. (Ed.). Studium Press, USA., ISBN: 9781933699523, pp: 67-119.
  100. Tosun, A., E.K. Akkol and E. Yesilada, 2009. Anti-inflammatory and antinociceptive activity of coumarins from Seseli gummiferum subsp. corymbosum (Apiaceae). Zeitschrift fur Naturforschung C, 64: 56-62.
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  101. Tatli, I.I., S. Sahpaz, E.K. Akkol, F. Martin-Nizard, B. Gressier, N. Ezer and F. Bailleul, 2009. Antioxidant, anti-inflammatory and antinociceptive potentials of Turkish medicinal plants. Pharm. Biol., 47: 916-921.
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  102. Onkol, T., S. Unlu, E. Kupeli, E. Yesilada and M.F. Sahin, 2009. Synthesis and analgesic and antiinflammatory activity of (6-Acyl-2-(3h)-Benzothiazolinon-3-yl) acetamide/propanamide derivatives. Turk. J. Pharm. Sci., 6: 93-106.
  103. Koca, U., I.P. Suntar, H. Keles, E. Yesilada and E.K. Akkol, 2009. In vivo anti-inflammatory and wound healing activities of Centaurea iberica Trev. ex Spreng. J. Ethnopharmacol., 126: 551-556.
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  104. Koca, U., G. Toker and E.K. Akkol, 2009. Assessment of anti-inflammatory and antinociceptive activities of Centaurea tchihatcheffii (Asteraceae) by using various in vivo models. Trop. J. Pharm. Res., 8: 193-200.
  105. Gokce, M., S. Utku and E. Kupeli, 2009. Synthesis and analgesic and anti-inflammatory activities 6-substituted-3 (2H)-pyridazinone-2-acetyl-2-(p-substituted/nonsubstituted benzal) hydrazone derivatives. Eur. J. Med. Chem., 44: 3760-3764.
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  106. Goekce, M., M.S. Colak, E. Kiipeli and M.F. Sahin, 2009. Synthesis and analgesic and anti-inflammatory activity of 6-phenyl/(4-methylphenyl)-3 (2H)-pyridazinon-2-propionamide derivatives. Arzneimittelforschung, 59: 357-363.
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  107. Erdemoglu, N., N.N. Turan, E. Kupeli, B. Sener and N. Abacioglu, 2009. Estimation of anti-inflammatory, Antinociceptive and antioxidant activities of Arctium minus (Hill) Bernh. ssp. Minus. J. Ethnopharmacol., 121: 318-323.
    CrossRef  |  PubMed  |  Direct Link  |  
  108. Berk, B., D.D. Erol, E. Kupeli and E. Yesilada, 2009. Design and synthesis of some (S)-2-(6-methoxynaphthalen-2-yl)-N-substituted ethyl propanamide derivatives as potent non-ulcerogenic anti-inflammatory and analgesic agents. Arzneimittel-Forschung/Drug Res., 59: 195-201.
  109. Akkol, E.K., U. Koca, I. Pesin, D. Yilmazer, G. Toker and E. Yesilada, 2009. Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models. J. Ethnopharmacol., 124: 137-141.
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  110. Akkol, E.K., R. Arif, F. Ergun and E. Yesilada, 2009. Sesquiterpene lactones with antinociceptive and antipyretic activity from two Centaurea species. J. Ethnopharmacol., 122: 210-215.
    CrossRef  |  Direct Link  |  
  111. Akkol, E.K., G. Avci, I. Kucukkurt, H. Keles, U. Tamer, S. Ince and E. Yesilada, 2009. Cholesterol-reducer, antioxidant and liver protective effects of Thymbra spicata L. var. spicata. J. Ethnopharmacol., 126: 314-319.
    CrossRef  |  Direct Link  |  
  112. Akkol, E.K., A. Guvenc and E. Yesilada, 2009. A comparative study on the antinociceptive and anti-inflammatory activities of five Juniperus taxa. J. Ethnopharmacol., 125: 330-336.
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  113. Akkol, E.K. and D. Ercil, 2009. Antinociceptive and anti-inflammatory activities of some Linaria species from Turkey. Pharm. Biol., 47: 188-194.
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  114. Tosun, A., E.K. Akkol, O. Bahadir and E. Yesilada, 2008. Evaluation of anti-inflammatory and antinociceptive activities of some Onosma L. species growing in Turkey. J. Ethnopharmacol., 120: 378-381.
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  115. Tatli, I.I., Z.S. Akdemir, E. Yesilada and E. Kupeli, 2008. Anti-inflammatory and antinociceptive potential of the methanolic extract of Verbascum salviifolium Boiss. Z. Naturforsch. C, 3: 196-202.
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  116. Tatli, I.I., E.K. Akkol, E. Yesilada and Z.S. Akdemir, 2008. Antinociceptive and anti-inflammatory activities of seven endemic Verbascum species growing in Turkey. Pharm. Biol., 46: 781-788.
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  117. Erdemoglu, N., E.K. Akkol, E. Yesilada and I. Calis, 2008. Bioassay-guided isolation of anti-inflammatory and antinociceptive principles from a folk remedy, Rhododendron ponticum L. leaves. J. Ethnopharmacol., 119: 172-178.
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  118. Akkol, E.K., F.N. Yalcin, D. Kaya, I. Calis, E. Yesilada and T. Ersoz, 2008. In vivo anti-inflammatory and antinociceptive actions of some Lamium species. J. Ethnopharmacol., 118: 166-172.
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  119. Akkol, E.K., F. Goger, M. Kosar and K.H.C. Baser, 2008. Phenolic composition and biological activities of Salvia halophila and Salvia virgata from Turkey. Food Chem., 108: 942-949.
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  120. Akkol, E.K., E. Yesilada and A. Guvenc, 2008. Valuation of anti-inflammatory and antinociceptive activities of Erica species native to Turkey. J. Ethnopharmacol., 116: 251-257.
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  121. Yesilada, E. and E. Kupeli, 2007. Clematis vitalba L. aerial part exhibits potent anti-inflammatory, antinociceptive and antipyretic effects. J. Ethnopharmacol., 110: 504-515.
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  122. Tunalier, Z., M. Kosar, E. Kupeli, I. Calis and K.H.C. Baser, 2007. Antioxidant, anti-inflammatory, anti-nociceptive activities and composition of Lythrum salicaria L. extracts. J. Ethnopharmacol., 110: 539-547.
    CrossRef  |  Direct Link  |  
  123. Tozkoparan, B., E. Kupeli, E. Yesilada and M. Ertan, 2007. Preparation of 5-aryl-3-alkylthio-l, 2, 4-triazoles and corresponding sulfones with anti-inflammatory-analgesic activity. Bioorg. Med. Chem., 15: 1808-1814.
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  124. Orhan, I., E. Kupeli, S. Terzioglu and E. Yesilada, 2007. Bioassay-guided isolation of kaempferol-3-O-beta-D-galactoside with anti-inflammatory and antinociceptive activity from the aerial part of Calluna vulgaris L. J. Ethnopharmacol., 144: 32-37.
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  125. Orhan, I., E. Kupeli, B. Sener and E. Yesilada, 2007. Appraisal of anti-inflammatory potential of the clubmoss, Lycopodium clavatum L. J. Ethnopharmacol., 109: 146-150.
    CrossRef  |  PubMed  |  Direct Link  |  
  126. Orhan, D.D., A. Hartevioglu, E. Kupeli and E. Yesilada, 2007. In vivo anti-inflammatory and antinociceptive activity of the crude extract and fractions from Rosa canina L. fruits. J. Ethnopharmacol., 112: 394-400.
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  127. Kupeli, E., I.I. Tatli, Z.S. Akdemir and E. Yesilada, 2007. Estimation of antinociceptive and anti-inflammatory activity on Geranium pratense subsp. finitimum and its phenolic compounds. J. Ethnopharmacol., 114: 234-240.
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  128. Kupeli, E., I.I. Tatli, Z.S. Akdemir and E. Yesilada, 2007. Bioassay-guided isolation of anti-inflammatory and antinociceptive glycoterpenoids from the flowers of Verbascum lasianthum Boiss. ex Bentham. J. Ethnopharmacol., 110: 444-450.
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  129. Kupeli, E., I. Orhan, S. Kusmenoglu and E. Yesilada, 2007. Evaluation of anti-inflammatory and antinociceptive activity of five anatolian Achillea species. Turk. J. Pharm. Sci., 4: 89-100.
  130. Kupeli, E., I. Orhan and E. Yesilada, 2007. Evaluation of some plants used in Turkish folk medicine for their anti-inflammatory and antinociceptive activities. Pharm. Biol., 45: 547-555.
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  131. Kupeli, E., F.P. Sahin, I. Calıs, E. Yesilada and N. Ezer, 2007. Phenolic compounds of Sideritis ozturkii and their in vivo anti-inflammatory and antinociceptive activities. J. Ethnopharmacol., 112: 356-360.
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  132. Kupeli, E., E. Yesilada, I. Calis and N. Ezer, 2007. In vivo anti-inflammatory and antinociceptive activity evaluation of phenolic compounds from Sideritis stricta. Zeitschrift fur Naturforschung C, 62: 519-525.
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  133. Kupeli, E., A. Tosun and E. Yesilada, 2007. Assessment of anti-inflammatory and antinociceptive activities of Daphne pontica L.(Thymelaeaceae). J. Ethnopharmacol., 113: 332-337.
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  134. Kupeli, E. and E. Yesilada, 2007. Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures. J. Ethnopharmacol., 112: 524-530.
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  135. Kosar, M., E. Kupeli, H. Malyer, V. Uylaser, C. Turkben and K.H.C. Baser, 2007. Effect of brining on biological activity of leaves of Vitis vinifera L.(Cv. Sultani Cekirdeksiz) from Turkey. J. Agric. Food Chem., 55: 4596-4603.
    CrossRef  |  Direct Link  |  
  136. Koksal, M., N. Gokhan, E. Kupeli, E. Yesilada and H. Erdogan, 2007. Analgesic and antiinflammatory activities of some new mannich bases of 5-nitro-2-benzoxazolinones. Arch. Pharm. Res., 30: 419-424.
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  137. Gokhan-Kelekci, N., S. Yabanoglu, E. Kupeli, U. Salgın and O. Ozgen et al., 2007. A new therapeutic approach in Alzheimer disease: Some novel pyrazole derivatives as dual MAO-B inhibitors and antiinflammatory analgesics. Bioorganic Med. Chem., 15: 5775-5786.
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  138. Duendar, Y., M. Goekce, E. Kuepeli and M.F. Sahin, 2007. Synthesis and analgesic and anti-inflammatory activity of ethyl (6-substituted-3 (2H)-pyridazinone-2-yl) acetate derivatives. Arzneimittelforschung, 57: 777-781.
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  139. Duendar, Y., B. Cakir, E. Kuepeli, M.F. Sahin and N. Noyanalpan, 2007. Synthesis of some new 1-acylthiosemicarbazides and 1, 2, 4-triazol-5-thiones, and their analgesic and anti-inflammatory activities. Turk. J. Chem., 31: 301-313.
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  140. Dogruer, D.S., S. Unlu, E. Kupeli, E. Banoglu and M.F. Sahin, 2007. Synthesis of 2-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]acetamide and 3-[5,6-diphenyl-3(2H)-pyridazinone-2-yl] propanamide derivatives as analgesic and anti inflamematory agents. Turk. J. Pharm. Sci., 4: 57-70.
    Direct Link  |  
  141. Dogdas, E., B. Tozkoparan, F.B. Kaynak, L. Eriksson, E. Kupeli, E. Yesilada and M. Ertan, 2007. Design and synthesis of some new Thiazolo [3, 2-b]-l, 2, 4-triazole-5 (6H)-ones substituted with flurbiprofen as anti-inflammatory and analgesic agents. Arzneimittelforschung, 57: 196-202.
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  142. Akkol, E.K., I.I. Tatli and Z.S. Akdemir, 2007. Antinociceptive and anti-inflammatory effects of saponin and iridoid glycosides from Verbascum pterocalycinum var. mutense Hub.-Mor. Zeitschrift Fur Naturforschung C, 62: 813-820.
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  143. Sukuroglu, M., E. Kupeli, E. Banoglu, S. Unlu, E. Yesilada and M.F. Sahin, 2006. Synthesis and analgesic activity of some 4, 6-disubstituted-3 (2H)-pyridazinone derivatives. Arzneimittelforschung, 56: 337-345.
    CrossRef  |  Direct Link  |  
  144. Orhan, D.D., E. Kupeli, E. Yesilada and F. Ergun, 2006. Anti-inflammatory and antinociceptive activity of flavonoids isolated from Viscum album ssp. album. Zeitschrift fur Naturforschung C, 61: 26-30.
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  145. Kupeli, E., M. Kartal, S. Aslan and E. Yesilada, 2006. Comparative evaluation of the anti-inflammatory and antinociceptive activity of Turkish Eryngium species. J. Ethnopharmacol., 107: 32-37.
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  146. Kupeli, E., I. Orhan, G. Toker and E. Yesilada, 2006. Anti-inflammatory and antinociceptive potential of Maclura pomifera (Rafin.) Schneider fruit extracts and its major isoflavonoids, scandenone and auriculasin. J. Ethnopharmacol., 107: 169-174.
    CrossRef  |  Direct Link  |  
  147. Kupeli, E., D.D. Orhan and E. Yesilada, 2006. Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice. J. Ethnopharmacol., 103: 455-460.
    CrossRef  |  Direct Link  |  
  148. Kupeli, E., A. Tosun and O. Bahadir, 2006. Evaluation of anti-inflammatory and antinociceptive activities of Helichrysum Gaertner Species (Asteraceae). Turk. J. Pharm. Sci., 3: 141-149.
  149. Kupeli, E., A. Tosun and E. Yesilada, 2006. Anti-inflammatory and antinociceptive activities of Seseli L. species (Apiaceae) growing in Turkey. J. Ethnopharmacol., 104: 310-314.
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  150. Kozan, E., E. Kupeli and E. Yesilada, 2006. Evaluation of some plants used in Turkish folk medicine against parasitic infections for their in vivo anthelmintic activity. J. Ethnopharmacol., 108: 211-216.
    PubMed  |  
  151. Iscan, G., N. Kirimer, M. Kurkcuoglu, T. Arabaci, E. Kupeli and Can K.H. Baser, 2006. Biological activity and composition of the essential oils of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp. aleppica. J. Agric. Food Chem., 54: 170-173.
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  152. Dundar, Y., B. Cakir, E. Kupeli and M.F. Sahin, 2006. Synthesis of 2(3H)-benzothiazolinone derivatives as analgesic and anti-inflammatory agents. Turk. J. Pharm. Sci., 3: 51-60.
    Direct Link  |  
  153. Avcı, G., E. Kupeli, A. Eryavuz, E. Yesilada and I. Kucukkurt, 2006. Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish folk medicine. J. Ethnopharmacol., 107: 418-423.
    CrossRef  |  Direct Link  |  
  154. Tozkoparan, B., E. Kuepeli, E. Yesilada, S. Isik, M. Oezalp and M. Ertan, 2005. Synthesis and evaluation of analgesic/anti-inflammatory and antimicrobial activities of 3-substituted-1, 2, 4-triazole-5-thiones. Arzneimittelforschung, 55: 533-540.
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  155. Sukuroglu, M., B.C. Ergun, S. Unlu, M.F. Sahin, E. Kupeli, E. Yesilada and E. Banoglu, 2005. Synthesis, analgesic and anti-inflammatory activities of [6-(3,5-dimethyl-4-chloropyrazole-1-yl)-3(2h)-pyridazinon-2-yl]acetamides. Arch. Pharm. Res., 28: 509-517.
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  156. Orhan, I., E. Küpeli., M. Aslan., M. Kartal and E. Yesilada, 2005. Bioassay-guided evaluation of anti-inflammatory and anticiceptive activities of pistachio, Pistacia vera L. J. Ethnopharmacol., 105: 235-240.
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  157. Kupeli, E., U.S. Harput, M. Varel, E. yesilada and I. Saracoglu, 2005. Bioassay-guided isolation of iridoid glucosides with antinociceptive and anti-inflammatory activities from Veronica anagallis-aquatica L. Ethnopharm. J., 102: 170-176.
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  158. Koksal, M., N. Gokhan, E. Kupeli, E. Yesilada and H. Erdogan, 2005. Synthesis analgesic and antiinflammatory properties of certain 5-/6-Acyl 3-(4-substitued-1-piperazinyl-methyl)-2-benzoxazolinones derivatives. Arch. Der Pharm., 338: 117-125.
  159. Gokhan, N., M. Koksal, E. Kupeli, E. Yesilada and H. Erdogan, 2005. Some new Mannich bases of 5-methyl-2-benzoxazolinones with analgesis and anti-inflammatory activities. Turk. J. Chem., 29: 445-454.
    Direct Link  |  
  160. Gokce, M., G. Bakır, M.F. Sahin, E. Kuepeli and E. Yesilada, 2005. Synthesis of new mannich bases of arylpyridazinones as analgesic and anti-inflammatory agents. Arzneimittelforschung, 55: 318-325.
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  161. Banoglu, E., C. Akoglu, S. Unlu, B.C. Ergun, E. Kupeli, E. Yesilada and M.F. Sahin, 2005. Synthesis of amide derivatives of [6-(3, 5-dimethylpyrazol-1-yl)-3 (2H)-pyridazinone-2-yl] acetic acid and their analgesic and anti-inflammatory properties. Arzneimittel-Forschung, 55: 520-527.
  162. Yesilada, A., S. Koyunoglu, S. Saygili, E. Kupeli, E. Yesilada, E. Bedir and I. Khan, 2004. Synthesis, antiinflammatory and analgesic activity screening of some new 4(3H)-quinozolinone derivatives. Arch. Der Pharm., 337: 96-104.
  163. Tozkoparan, B., N. Goekhan, E. Kuepeli, E. Yesilada and M. Ertan, 2004. Synthesis, characterization and anti-inflammatory-analgesic properties of 6-(α-Amino-4-chlorobenzyl) thiazolo [3, 2-b]-1, 2, 4-triazol-5-ols. Arzneimittelforschung, 54: 35-41.
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  164. Toker, G., E. Kupeli, M. Memisoglu and E. Yesilada, 2004. Flavonoids with antinociceptive and anti-inflammatory activities from the leaves of Tilia argentea (silver linden). J. Ethnopharmacol., 95: 393-397.
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  165. Sahina, M.F., B. Badıcoglu, M. Gokce, E. Kupeli and E. Yesilada, 2004. Synthesis and analgesic and antiinflammatory activity of methyl 6‐substituted‐3 (2H)‐pyridazinone‐2‐ylacetate derivatives. Arch. der Pharmazie, 337: 445-452.
    CrossRef  |  Direct Link  |  
  166. Kupeli, E., M. Aslan, I. Gurbuz and E. Yesilada, 2004. Evaluation of in vivo biological activity profile of isoorientin. Zeitschrift fur Naturforschung C, 59: 787-790.
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  167. Gokce, M., M.F. Sahin, E. Kupeli and E. Yesilada, 2004. Synthesis and analgesic and anti-inflammatory activity of new 3(2H)-pyridazinone derivatives. Arzneimittel-Forschung-Drug Res., 7: 396-401.
  168. Dogruer, D.S., E. Kupeli, E. Yesilada and M.F. Sahin, 2004. Synthesis of new 2‐[1 (2H)‐phthalazinon‐2‐yl] acetamide and 3‐[1 (2H)‐phthalazinon‐2‐yl] propanamide derivatives as antinociceptive and anti‐inflammatory agents. Arch. der Pharm., 337: 303-310.
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  169. Banoglu, E., C. Akoglu, S. Uenlue, E. Kuepeli, E. Yesilada and M.F. Sahin, 2004. Amide Derivatives of [6‐(5‐Methyl‐3‐phenylpyrazole‐1‐yl)‐3 (2H)‐pyridazinone‐2‐yl] acetic acids as potential analgesic and anti‐inflammatory compounds. Arch. der Pharm., 337: 7-14.
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  170. Arif, R., E. Kupeli and F. Ergun, 2004. The biological activity of Centaurea L. Species. Gazi Univ. J. Sci., 17: 151-166.
  171. Unlu, S., T. Onkol, Y. Dundar, B. Okcelik and E. Kupeli et al., 2003. Synthesis analgesic and antiinflammatory activity of some new 6-acyl-2-benzothiazolinone derivatives with acetic acid and propanoic acis residues. Arch. Der Pharm., 336: 353-361.
  172. Unlu, S., S. Baytas, E. Kupeli and E. Yesilada, 2003. Studies on novel 7-acyl-5-chloro-2-benzoxazolinone derivatives as potent analgesic and anti-inflammatory agents. Arch. Der Pharm., 336: 310-332.
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