Dr. Huang  Guan Jhong
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Dr. Huang Guan Jhong

Associate Professor
China Medical University, China


Highest Degree
Ph.D. in Chemistry from National Taiwan University College of Medicine, Taiwan

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Area of Interest:

Pharmacology and Toxicology
100%
Immunopharmacology
62%
Antioxidants
90%
Respiratory Pharmacology
75%
Food Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Hsieh, Y.H., J.S. Deng, H.P. Pan, J.C. Liao, S.S. Huang and G.J. Huang, 2017. Sclareol ameliorate lipopolysaccharide-induced acute lung injury through inhibition of MAPK and induction of HO-1 signaling Int. Immunopharmacol., 44: 16-25.
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  2. Chen, J.J., C.C. Huang, H.Y. Chang, P.Y. Li and Y.C. Liang et al., 2017. Scutellaria baicalnsis ameliorate acute lung injury by suppressing inflammation in Vitro and in Vivo. Am. J. Chin. Med., .
  3. Yang, C.S., H.C. Huang, S.Y. Wang, P.J. Sung, G.J. Huang, J.J. Chen and Y.H. Kuo, 2016. New Diphenol and Isocoumarins from the aerial part of lawsonia inermis and their inhibitory activities against NO production. Mol., 21: 1299-1299.
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  4. Yang, C.H., H.Y. Chang, Y.C. Chen, C.C. Lu, S.S. Huang, G.J. Huang and H.C. Lai, 2016. Ethanol extract of Phellinus merrillii protects against diethylnitrosamine- and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats. Chin. J. Integr. Med., 10.1007/s11655-016-2513-2.
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  5. Wang, S.H., C.H. Liang, F.P. Liang, H.Y. Ding and G.J. Huang et al., 2016. The inhibitory mechanisms study of 5,6,4’-Trihydroxy-7,3’-Dimethoxyflavone against the LPS-induced macrophage inflammatory responses through the antioxidant ability. Mol., 21: 136-149.
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  6. Shia, P.H., S.Y. Wang, H.L. Lay and G.J. Huang, 2016. 4, 7-dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells. Int. Immunopharmol., 31: 186-194.
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  7. Li, K.C., Y.L. Ho, C.Y. Chen, W.T. Hsieh, Y. S. Chang and G.J. Huang, 2016. Lobeline improve acute lung injury via nuclear Factor-kB-signaling pathway and oxidative stress. Respir. Physiol. Neurobiol., 225: 19-30.
  8. Huang, S.S., S.Y. Su, J.S. Chang, H.J. Lin, W.T. Wu, J.S. Deng and G.J. Huang, 2016. Antioxidants, Anti-inflammatory, and antidiabetic effects of the aqueous extracts from glycine species and its bioactive compounds. Bot. Stud., .
  9. Chang, C.I., C.C. Chen, C.Y. Chao, S.Y. Wang and G.J. Huang et al., 2016. Sesquiterpenoids and diterpenoids from the wood of cunninghamia konishii and their inhibitory activities against NO production. Mol., 21: 490-490.
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  10. Shie, P.H., S.S. Huang, J.S. Deng and G.J. Huang, 2015. Spiranthes sinensis (Pers.) Ames. suppress production of pro-inflammatory mediators through the down-regulation of NF-κB signaling pathway and up-regulation of HO-1/Nrf2 antioxidant protein. Am. J. Chin. Med., 43: 969-987.
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  11. Li, Y.Y., S.S. Huang, M.M. Lee, J.S. Deng and G.J. Huang, 2015. Anti-inflammatory activities of cardamonin from alpinia katsumadai through heme oxygenase-1 induction and inhibition of nf-κb and mapk signaling pathway in the carrageenan-induced paw edema. Int. Immunopharmacol., 25: 332-339.
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  12. Li, K.C., Y.L. Ho, W.T. Hsieh, S.S. Huang, Y.S. Chang and G.J. Huang, 2015. Apigenin-7-Glycoside prevents lps-induced acute lung injury via downregulation of oxidative enzyme expression and protein activation through inhibition of MAPK phosphorylation. Int. J. Mol. Sci., 16: 1736-1754.
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  13. Li, K.C., Y.L. Ho, G.J. Huang and C. Yuan-Shiun, 2015. Anti-oxidative and Anti-inflammatory effects of Lobelia chinensis in vitro and in vivo. Am. J. Chin. Med., 43: 269-287.
    CrossRef  |  PubMed  |  
  14. Kuo, P.C., T.D. Thang, G.J. Huang, B.S. Huang, L.T.H. Mai , M.L. Yang and T.S. Wu, 2015. Flavonoids from the fruits of desmos cochinchinesis var. fulvecens and their inhibitory effects on no production. Chem. Nat. Comp., 51: 152-155.
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  15. Chien, T.M., P.C. Hsieh, S.S. Huang, J.S. Deng, Y.L. Ho, Y.S. Chang and G.J. Huang, 2015. Acanthopanax trifoliatus Inhibits lipopolysaccharide-induced inflammatory response in vitro and in vivo. Kaohsiung J. Med. Sci., 31: 499-509.
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  16. Chen, H.J., Y.H. Huang, G.J. Huang, S.S. Huang, T.J. Chow and Y.H. Lin, 2015. Sweet potato SPAP1 is a typical aspartic protease and participates in ethephon-mediated leaf senescence. J. Plant Physiol., 180: 1-17.
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  17. Chen, H.J., S.H. Liang, G.J. Huang and Y.H. Lin, 2015. Sweet potato cysteine proteases SPAE and SPCP2 participate in sporamine degradation during storage root sprouting. J. Plant Physiol., 186: 39-49.
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  18. Chang, F.P., C.C. Chen, H.C. Huang, S.Y. Wang and G.J. Huang et al., 2015. A new bithiophene from the root of Echinops grijsii. Nat. Prod. Commun., 10: 2147-2149.
    PubMed  |  
  19. Wang, R., Y.Q. Liu, W. Ha, Y.P. Shi and T.L. Hwang et al., 2014. In vitro anti-inflammatory effects of diterpenoids and sesquiterpenoids from traditional Chinese medicine Siegesbeckia pubescens. Bioorg. Med. Chem. Lett., 24: 3944-3947.
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  20. Wang, B.S., K.L. Leu, G.J. Huang, C.F. Yeh, H.M. Tai, W.Y. Ho and M.H. Huang, 2014. Protective effects of an aqueous Pericarpium granati extract against inflammatory damage in mice. J. Funct. Foods, 9: 183-191.
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  21. Huang, S.S., J.S. Deng, J.G. Lin, C.Y. Lee and G.J. Huang, 2014. Anti-inflammatory effects of trilinolein from panax notoginseng through the suppression of NF-κB and MAPK expressions and proinflammatory cytokines expressions. Am. J. Chin. Med., 42: 1485-1506.
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  22. Huang, S.S., J.S. Deng, H.J. Chen, Y.H. Lin and G.J. Huang, 2014. Antioxidant activities of two metallothionein-like proteins from sweet potato (Ipomoea batatas [L.] Lam. ‘Tainong 57’) storage roots and their synthesized peptides. Bot. Stud., 10.1186/s40529-014-0064-4.
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  23. Huang, G.J., J.S. Deng, C.C. Chen, C.J. Huang, P.J. Sung, S.S. Huang and Y.H. Kuo, 2014. Methanol extract of Antrodia camphorata protects against lipopolysaccharide-induced acute lung injury by suppressing NF-κB and MAPK pathways in mice. J. Agric. Food Chem., 62: 5321-5329.
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  24. Chan, Y.Y., S.H. Juang, G.J. Huang, Y.R. Liao, C.C. Wu, H.T. Chang and T.S. Wu, 2014. The Constituents of Michelia compressa var. formosana and their bioactivities. Int. J. Mol. Sci., 15: 10926-10935.
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  25. Yang, C.P., G.J. Huang, H.C. Huang, Y.C. Chen and C.I. Chang et al., 2013. The effect of the aerial part of lindera akoensis on lipopolysaccharides (LPS)-Induced nitric oxide production in RAW264.7 cells. Int. J. Mol. Sci., 14: 9168-9181.
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  26. Wang, B.S., G.J. Huang, Y.H. Lu and L.W. Chang, 2013. Anti-inflammatory effects of an aqueous extract of Welsh onion green leaves in mice. Food Chem., 138: 751-756.
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  27. Thang, T.D., P.C. Kuo, G.J. Huang, N.H. Hung and B.S. Huang et al., 2013. Chemical constituents from the leaves of Annona reticulata and their inhibitory effects on NO production. Mol., 18: 4477-4486.
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  28. Shen, D.Y., S.H. Juang, P.C. Kuo, G.J. Huang and Y.Y. Chan et al., 2013. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int. J. Mol. Sci., 14: 496-514.
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  29. Liaw, C.C., Y.C. Chen, G.J. Huang, Y.C. Tsai and S.C. Chien et al., 2013. Anti-inflammatory lanostanoids and lactone derivatives from Antrodia camphorata. J. Nat. Prod., 76: 489-495.
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  30. Liao, J.C., S.S. Huang, J.S. Deng, C.Y. Lee, Y.C. Lin and G.J. Huang, 2013. Chemical characterization and in vivo anti-Inflammatory activities of Actinidia callosa var. ephippioides via suppression of proinflammatory cytokines. Am. J. Chin. Med., 41: 405-423.
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  31. Liao, J.C., J.S. Deng, C.S. Chiu, S.S. Huang, W.C. Hou, W.C. Lin and G.J. Huang, 2013. Chemical compositions, anti-inflammatory, antiproliferative and radical-scavenging activities of Actinidia callosa var. ephippioides. Am. J. Chin. Med., 40: 1047-1062.
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  32. Liao, C.R., Y.L. Ho, G.J. Huang, C.S. Yang, C.Y. Chao, Y.S. Chang and Y.H. Kuo, 2013. One lignanoid compound and four triterpenoid compounds with anti-inflammatory activity from the leaves of Elaeagnus oldhamii Maxim. Mol., 18: 13218-13227.
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  33. Huang, S.S., C.S. Chiu, T.H. Lin, M.M. Lee and G.J. Huang et al., 2013. Antioxidant and anti-inflammatory activities of aqueous extract of Centipeda minima. J. Ethnopharmacol., 147: 395-405.
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  34. Huang, H.C., G.J. Huang, C.C. Liaw, C.S. Yang and C.P. Yang et al., 2013. A new megastigmane from Kalanchoe tubiflora (Harvey) Hamet. Phytochem. Lett., 6: 379-382.
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  35. Huang, G.J., J.S. Deng, S.S. Huang, S.Y. Wang, Y.S. Chang and Y.H. Kuo, 2013. Bioassay guided isolation and identification of anti-inflammatory active compounds from the root of Ficus formosana. J. Agric. Food Chem., 61: 11008-11015.
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  36. Huang, G.J., J.S. Deng, S.S. Huang, C.Y. Lee and W.C. Hou et al., 2013. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Food Chem., 141: 3020-3027.
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  37. Huang, G.J., J.S. Deng, H.J. Chen, S.S. Huang, C.C. Shih, C.Y. Lee and Y.H, Lin, 2013. Dehydroascorbate reductase and monodehydroascorbate reductase activities of two metallothionein-like proteins from sweet potato (Ipomoea batatas [L.] Lam. ‘Tainong 57’) storage roots. Bot. Stud., 10.1186/1999-3110-54-7.
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  38. Deng, J.S., S.S. Huang, T.H. Lin, M.M. Lee and G.J. Huang et al., 2013. The analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice. J. Agric. Food Chem., 61: 5064-5071.
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  39. Chiu, C.S., J.S. Deng, H.Y. Chang, Y.C. Chen and G.J. Huang et al., 2013. Antioxidant and anti-inflammatory properties of Taiwanese Yam (Dioscorea japonica Thunb. var. pseudojaponica (Hayata) Yamam.) and its reference compounds. Food Chem., 141: 1087-1096.
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  40. Chen, Y.C., Y.C. Li, B.J. You, W.T. Chang and G.J. Huang et al., 2013. Diterpenoids with anti-inflammatory activity from the wood of Cunninghamia konishii. Mol., 18: 682-689.
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  41. Chen, Y.C., H.Y. Chang, J.S. Deng, J.J. Chen and G.J. Huang et al., 2013. Hispolon from Phellinus linteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukaemia cells. Am. J. Chin. Med., 41: 1439-1457.
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  42. Chen, Y.C., H.L. Chiu, C.Y. Chao, W.H. Lin, K.C. Louis, G.J. Huang and Y.H. Kuo, 2013. New Anti-Inflammatory aromatic components from antrodia camphorata. Int. J. Mol. Sci., 14: 4629-4639.
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  43. Chen, H.J., Y.J. Tsai, C.Y. Shen, T.N. Tsai, G.J. Huang and Y.H. Lin, 2013. NADPH oxidase inhibitor diphenyleneiodonium and reduced glutathione mitigate ethephon-mediated leaf senescence, H2O2 elevation and senescence-associated gene expression in sweet potato (Ipomoea batatas). J. Plant Physiol., 170: 1471-1483.
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  44. Chen, H.J., Y.J. Tsai, C.Y. Shen, T.N. Tsai, G.J. Huang and Y.H. Lin, 2013. Ectopic expression of sweet potato cysteine protease SPCP3 alters phenotypic traits and enhances drought stress sensitivity in transgenic arabidopsis plants. J. Plant Growth Regul., 32: 108-121.
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  45. Yang, C.P., G.J. Huang, H.C. Huang, Y.C. Chen AND C.I. Chang et al., 2012. A new butanolide compound from the aerial part of Lindera akoensis with Anti-inflammatory activity. Mol., 17: 6585-6592.
    CrossRef  |  Direct Link  |  
  46. Wang, B.S., G.J. Huang and M.H. Huang, 2012. Antioxidant and anti-inflammatory activities of aqueous extracts of Schizonepeta tenuifolia Briq. Food Chem. Toxicol., 50: 526-531.
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  47. Sheu, M.J., J.S. Deng, M.H. Huang, C.H. Wu, S.S. Huang and G.J. Huang, 2012. Antioxidant and anti-inflammatory properties of Dichondra repens Forst. and its reference compounds. Food Chem., 132: 1010-1018.
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  48. Shen, D.Y., C.H. Chao, H.H. Chan, G.J. Huang and T.L. Hwang et al., 2012. Bioactive constituents of Clausena lansium and a method for discrimination of aldose enantiomers. Phytochemistry, 82: 110-117.
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  49. Liu, S.L., J.S. Deng, C.S. Chiu, W.C. Hou and G.J. Huang et al., 2012. Involvement of heme oxygenase-1 participates in anti-inflammatory and analgesic effects of aqueous extract of Hibiscus taiwanensis. Evidence Based Compl. Altern. Med., 10.1155/2012/132859.
    CrossRef  |  Direct Link  |  
  50. Liu, C.Y., Y.C. Lin, T.H. Huang, W.H. Peng and G.J. Huang, 2012. Antioxidant, Anti-inflammatory, and Antiproliferative Activities of Taxillus sutchuenensis. Am. J. Chin. Med., 40: 335-348.
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  51. Liao, J.C., J.S. Deng, Y.C. Lin, C.Y. Lee and G.J. Huang et al., 2012. Antioxidant, anti-nociceptive, and anti-inflammatory activities from actinidia callosa var. callosa in vitro and in vivo. Evidence Based Compl. Altern. Med., 10.1155/2012/129152.
    CrossRef  |  Direct Link  |  
  52. Liao, J.C., J.S. Deng, C.S. Chi, W.C.Hou, S.S. Huang, P.H. Shie and G.J. Huang, 2012. Anti-inflammatory activities of cinnamomum cassia constituents in vitro and in vivo. Evidence Based Compl. Altern. Med., 10.1155/2012/429320.
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  53. Liao, J.C., C.S. Chiu, H.J. Chen, S.S. Huang and G.J. Huang et al., 2012. Characterization of a novel cyclophilin-type peptidylprolyl isomerase protein from sweet potato storage roots. Bot. Stud., 53: 315-324.
    Direct Link  |  
  54. Huang, G.J., Y.C. Lin, J.S. Deng, H.J. Chen, J.C. Liao, S.S. Huang and Y.H. Lin, 2012. A novel trypsin inhibitor from sweet potato (Ipomoea batatas Lam.) leaves and its synthesized peptides with antioxidant activities in vitro. Bot. Stud., 53: 215-222.
    Direct Link  |  
  55. Huang, G.J., S.S. Huang and J.S. Deng, 2012. Anti-inflammatory activities of inotilone from Phellinus linteus through the inhibition of MMP-9, NF-kB, and MAPK activation in vitro and in vivo. Plos One, 10.1371/journal.pone.0035922.
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  56. Huang, G.J., M.V.B. Reddy, P.C. Kuo, C.H. Huang and H.C. Shih et al., 2012. A concise synthesis of viscolin, and its anti-inflammatory effects through the suppression of iNOS, COX-2, ERK phosphorylation and proinflammatory cytokines expressions. Eur. J. Med. Chem., 48: 371-378.
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  57. Huang, G.J., M.H. Huang, C.S. Chiu, S.S. Huang, P.H. Shie, M.T. Yen and B.S. Wang, 2012. Antioxidant, analgesic, and anti-inflammatory activities of aqueous extracts from Fructus Ligustri Lucidi. J. Food Drug Anal., 20: 617-627.
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  58. Huang, G.J., J.S. Deng, S.S. Huang, S.S. Lin and Y.Y. Shao et al., 2012. Protective effects of antrosterol against carbon tetrachloride-induced acute liver injury in mice. Food Chem., 132: 709-716.
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  59. Huang, G.J., J.S. Deng, J.C. Liao, W.C. Hou, S.Y. Wang, P.J. Sung and Y.H. Kuo, 2012. Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis. J. Agric. Food Chem., 60: 1673-1681.
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  60. Huang, G.J., J.S. Deng, H.J. Chen, S.S. Huang, J.C. Liao, W.C. Hou and Y.H. Lin, 2012. Defensin Protein from sweet potato (Ipomoea batatas [L.] Lam. ‘Tainong 57’) storage roots exhibits antioxidant activities in vitro and ex vivo. Food Chem., 135: 861-867.
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  61. Huang, G.J., J.S. Deng, H.J. Chen, S.S. Huang and C.H. Wu et al., 2012. Inhibition of reactive nitrogen species in Vitro and ex Vivo by thioredoxin h2 from sweet potato ‘Tainong 57’ storage roots. Food Chem., 131: 552-557.
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  62. Huang, G.J., C.S. Chiu, S.S. Huang, P.H.Shie, T.H. Lin and J.S. Deng, 2012. Anti-inflammatory activities of aqueous extract of mesona procumbens in experimental animals. J. Sci. Food Agric., 92: 1186-1193.
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  63. Huang, G.J., C.H. Pan, T.S. Wu and C.H. Wu, 2012. Anti-inflammatory effects of ethanolic extract of Antrodia salmonea in the lipopolysaccharide-stimulated RAW246.7 macrophages and the λ-carrageenan-induced paw edema model. Food Chem. Toxicol., 50: 1485-1493.
    CrossRef  |  Direct Link  |  
  64. Huang, G.J., C.H. Pan and C.H. Wu, 2012. Sclareol exhibits antiinflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema model. J. Nat. Prod., 75: 54-59.
    CrossRef  |  Direct Link  |  
  65. Huang, G.J., B.S. Wang, W.C. Lin, S.S. Huang, C.Y. Lee, M.T. Yen and M.H. Huang, 2012. Antioxidant and anti-inflammatory properties of longan (Dimocarpus longan Lour.) pericarp. Evidence Based Compl. Altern. Med., 10.1155/2012/709483.
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  66. Ho, Y.L., S.S. Huang, J.S. Deng, Y.H. Lin, Y.S. Chang and G.J. Huang, 2012. In vitro antioxidant properties and total phenolic contents of wetland medicinal plants in Taiwan. Bot. Stud., 53: 55-66.
    Direct Link  |  
  67. Ho, Y.L., K.C. Li, W. Chao, Y.S. Chang and G.J. Huang, 2012. Korean red ginseng suppresses metastasis of human hepatoma SK-Hep1 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen activator. Evidence Based Compl. Altern. Med., 10.1155/2012/965846.
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  68. Deng, J.S., Y.C. Chang, C.L. Wen, J.C. Liao and W.C. Hou et al., 2012. Hepatoprotective effect of the ethanol extract of Vitis thunbergii on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities. J. Ethnopharmacol., 142: 795-803.
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  69. Chien, Y.C., G.J. Huang, H.C. Cheng, C.H. Wu and M.J. Sheu, 2012. Hispolon attenuates balloon-injured neointimal formation and modulates vascular smooth muscle cell migration via AKT and ERK phosphorylation. J. Nat. Prod., 75: 1524-1533.
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  70. Chen, Y.Y., P.Y. Chou, F.C. Liu, Y.C. Chien and G.J. Huang et al., 2012. Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppresses CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38 and PI3K/Akt signaling pathways. Evidence Based Compl. Altern. Med., 10.1155/2012/378415.
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  71. Chen, H.J., Z.W. Lin, G.J. Huang and Y.H. Lin, 2012. Sweet potato calmodulin SPCAM is involved in salt stress-mediated leaf senescence, H2O2 elevation and senescence-associated gene expression. J. Plant Physiol., 169: 1892-1902.
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  72. Chen, H.J., S.D.Wu, Z.W. Lin, G.J. Huang and Y.H. Lin, 2012. Cloning and characterization of a sweet potato calmodulin SPCAM that participates in ethephon-mediated leaf enescence, H2O2 elevation and senescence-associated gene expression. J. Plant Physiol., 169: 529-541.
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  73. Chen, H.J., S.D. Wu, G.J. Huang, C.Y. Shen, M. Afiyanti, W.J. Li and Y.H. Lin, 2012. Expression of a cloned sweet potato catalase SPCAT1 alleviates ethephon-mediated leaf senescence and H2O2 elevation. J. Plant Physiol., 169: 86-97.
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  74. Chang, T.N., J.S. Deng, Y.C. Chang, C.Y. Lee and L. Jung-Chun et al., 2012. Ameliorative effects of scopoletin from Crossostephium chinensis against inflammation pain and its mechanisms in mice. Evidence-Based Complement. Altern. Med. 10.1155/2012/595603.
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  75. Wen, C.L., C.C. Chang, S.S. Huang, C.L. Kuo, S.L. Hsu, J.S. Deng and G.J. Huang, 2011. Anti-inflammatory effects of methanol extract of Antrodia cinnamomea mycelia both in vitro and in vivo. J. Ethnopharmacol., 137: 575-584.
    PubMed  |  
  76. Tsai, J.C., G.J. Huang, T.H. Chiu, S.S. Huang and S.C. Huang et al., 2011. Antioxidant activities and phenolic components from various plants of Desmodium species. Afri. J. Pharm. Pharmacol., 5: 468-476.
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  77. Lai, Z.R., Y.L. Ho, S.C. Huang, T.H. Huang and S.C. Lai et al., 2011. Antioxidant, Anti-inflammatory, and Antiproliferative Activities of Kalanchoe gracilis (L.) DC Stem. Am. J. Chin. Med., 39: 1275-1290.
    CrossRef  |  Direct Link  |  
  78. Huang, S.S., C.S. Chiu, H.J. Chen, W.C. Hou and M.J. Sheu et al., 2011. Antinociceptive activities and the mechanisms of anti-inflammation of asiatic acid in mice. Evidence-Based Complementary Altern. Med. 10.1155/2011/895857.
    CrossRef  |  PubMed  |  
  79. Huang, M.H., S.S. Huang, B.S. Wang, C.H. Wu and M.J. Sheu et al., 2011. Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo. J. Ethnopharmacol., 133: 743-750.
    CrossRef  |  PubMed  |  
  80. Huang, M.H., B.S. Wang, C.S. Chiu, S. Amagaya and W.T. Hsieh et al., 2011. Antioxidant, antinociceptive and anti-inflammatory activities of Xanthii Fructus extract. J. Ethnopharmacol., 135: 545-552.
    PubMed  |  
  81. Huang, G.J., W.T. Hsieh, H.Y. Chang, S.S. Huang, Y.C. Lin and Y.H. Kuo, 2011. Glucosidase and aldose reductase inhibitory activities from the fruiting body of Phellinus merrillii. J. Agric. Food Chem., 59: 5702-5706.
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  82. Huang, G.J., T.L. Lu, C.S. Chiu, H.J. Chen and C.H. Wu et al., 2011. Sweet potato storage root defensin and their peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activity in vitro. Bot. Stud., 52: 257-264.
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  83. Huang, G.J., S.S. Huang, S.S. Lin, I.C. HSieh, W.C. Hou and Y.H. Kuo, 2011. Anti-inflammatory activities of 6beta-acetoxy-7alpha-hydroxyroyleanone from Taiwania cryptomerioides Hayata ex vivo and in vivo. J. Agric. Food Chem. .
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  85. Huang, G.J., J.S. Deng, C.S. Chiu, J.C. Liao, W.T. Hsieh, M.J. Sheu and C.H. Wu, 2011. Hispolon protects against acute liver damage in the rat by inhibiting lipid peroxidation, proinflammatory cytokine, oxidative stress and down-regulating the expressions of iNOS, COX-2, and MMP-9. Evidence Based Complementary Alterna. Med. .
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  87. Hsieh, P.C., Y.L. Ho, G.J. Huang, M.H. Huang and Y.C. Chiang et al., 2011. Hepatoprotective effect of the aqueous extract of Flemingia macrophylla on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities. Am. J. Chin. Med., 39: 349-365.
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  88. Deng, J.S., C.S. Chiu, S.S. Huang, P.H. Shie, T.H. Lin and G.J. Huang, 2011. Antioxidant, Analgesic, and Anti-inflammatory activities of the ethanolic extracts of Taxillus liquidambaricola. J. Ethnopharmacol., 137: 1161-1171.
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  89. Chou, P.Y., G.J. Huang, C.H. Pan, Y.C. Chien and Y.Y. Chen et al., 2011. Trilinolein inhibits proliferation of human non-small cell lung carcinoma A549 through the modulation of PI3K/Akt pathway. Am. J. Chin. Med., 39: 803-815.
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  93. Chang, T.N., S.S. Huang, Y.S. Chang, C.I. Chang and H.L. Yang et al., 2011. Analgesic effects and the mechanisms of anti-inflammation of taraxeren-3-one from Diospyros maritima in Mice. J. Agric. Food Chem., 59: 9112-9119.
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  94. Chang, C.T., S.S. Huang, S.S. Lin, S. Amagaya and H.Y. Ho et al., 2011. Anti-inflammatory activities of tormentic acid from suspension cells of Eriobotrya Japonica ex vivo and in vivo. Food Chem., 127: 1131-1137.
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  96. Lu, T.L., G.J. Huang, H.J. Wang, J.L. Chen, H.P. Hsu, T.J. Lu, 2010. Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy. Biochem. Biophys. Res. Comm., 398: 26-31.
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  98. Huang, G.J., C.S. Chiu, C.H. Wu, S.S. Huang and W.C. Hou et al., 2010. Redox Status of Bowman-Birk Inhibitor from soybean influence its in vitro antioxidant activities. Bot. Stud., 51: 431-437.
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  99. Huang, G.J., C.M. Yang, Y.S. Chang, S. Amagaya and H.C. Wang et al., 2010. Hispolon suppresses SK-Hep1 human hepatoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen activator through the PI3K/Akt and ERK signaling pathways. J. Agric. Food Chem., 58: 9468-9475.
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  101. Chou, P.Y., G.J. Huang, C.H. Wu, Y.C. Chien and J.S.Chen et al., 2010. Analgesic and anti-inflammatory activies of an ethanol extract of Dunaliella salina Teod (CHLOROPHYCEAE). J. Food Biochem., 34: 1288-1302.
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  102. Chen, H.J., Y.J. Tsai, W.S. Chen, G.J. Huang, S.S. Huang and Y.H. Lin, 2010. Ethephon-mediated effects on leaf senescence are affected by reduced glutathione and EGTA in sweet potato detached leaves. Bot. Stud., 51: 171-181.
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  103. Chen, H.J., C.T. Su, C.H. Lin, G.J. Huang and Y.H. Lin, 2010. Expression of sweet potato cysteine protease SPCP2 altered developmental characteristics and stress responses in transgenic Arabidopsis plants. J. Plant Physiol., 167: 838-847.
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  104. Sheu, M.J., P.Y. Chou, H.C. Cheng, C.H. Wu and G.J. Huang et al., 2009. Analgesic and anti-inflammatory activities of a water extract of Trachelospermum jasminoides (Apocynaceae). J. Ethnopharmacol., 126: 332-338.
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  105. Ling, L.T., G.J. Huang, T.J. Lu, J.B. Wu and C.H. Wu et al., 2009. Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells. Food Chem. Toxicol., 47: 2013-2021.
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  106. Huang, S.S., H.J. Hung, C.S. Chiu, H.J. Chen and S.S. Lin et al., 2009. Sweet potato trypsin inhibitor with thioltransferase-like and glutathione S-transferase-like activities. Bot. Stud., 50: 443-450.
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  107. Huang, G.J., S.S. Huang, H.J. Chen, Y.S. Chang and S.J. Chang et al., 2009. Cloning and expression of aspartic proteinase cDNA from sweet potato storage roots. Bot. Stud., 50: 149-158.
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  108. Chen, H.J., G.J. Huang, W.S. Chen, C.T. Su, W.C. Hou and Y.H. Lin, 2009. Molecular cloning and expression of a sweet potato cysteine protease SPCP1 from senescent leaves. Bot. Stud., 50: 159-170.
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  109. Chang, T.N., G.J. Huang, Y.L. Ho, S.S. Huang, H.Y. Chang and Y.S. Chang, 2009. Antioxidant and antiproliferative activities of Crossostephium chinensis (L.) makino. Am. J. Chin. Med., 37: 797-814.
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  110. Chang, H.Y., M.J. Sheu, C.H. Yang, Z.C. Leu and Y.S. Chang et al., 2009. Analgesic effects and the mechanisms of anti-inflammation of hispolon in mice. Evidence Based Complementary Altern. Med. 10.1093/ecam/nep027.
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  112. Lin, K.h., J.C. Liao, W.H. Peng, M.T. Hsieh, J.B. Wu and G.J. Huang, 2008. Antioxidant activity and total polyphenol content of five species of actinidia. Mid-Taiwan J. Med., 13: 19-25.
  113. Huang, S.S., G.J. Huang, Y.L. Ho, Y.H. Lin and H.J. Hung et al., 2008. Antioxidant and antiproliferative activities of the four Hydrocotyle species from Taiwan. Bot. Stud., 49: 311-322.
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  114. Huang, S.S., G.J. Huang, W.H. Peng, Y.L. Ho and M.J. Chang et al., 2008. Analgesic and anti-inflammatory activities of the aqueous extract of Hydrocotyle batrachium hance in mice. Mid. Taiwan. J. Med., 13: 179-185.
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  116. Huang, G.J., M.J. Sheu, Y.S. Chang, T.L. Lu, H.Y. Chang, S.S. Huang and Y.H. Lin, 2008. Isolation and characterization of invertase inhibitor from sweet potato storage roots. J. Sci. Food Agric., 88: 2615-2621.
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  117. Huang, G.J., H.Y. Chang, H.J. Chen, T.L. Lu, Y.S. Chang, M.J. Sheu and Y.H. Lin, 2008. Effects of Trypsin inhibitor on plasma antioxidant activity and lipid levels in mice from sweet potato roots. J. Sci. Food Agric., 88: 2556-2562.
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  118. Huang, G.J., H.J. Chen, Y.S. Chang, T.L. Lu and Y.H. Lin, 2008. Sweet potato storage root thioredoxin h2 with both dehydroascorbate reductase and monodehydroascorbate reductase activities. Bot. Stud., 49: 1-7.
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  119. Huang, G.J., H.C. Lai, Y.S. Chang, T.L. Lu, M.J. Sheu, H.Y. Chang and Y.H. Lin, 2008. Antimicrobial, dehydroascorbate reductase and monodehydroascorbate reductase activities of defensin from sweet potato (Ipomoea batatas (L.) Lam 'Tainong 57') storage roots. J. Agric. Food Chem., 56: 2989-2995.
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  120. Chen, H.J., I.C. Wen, G.J. Huang, W.C. Hou and Y.H. Lin, 2008. Expression of sweet potato asparaginyl endopeptidase caused altered phenotypic characteristics in transgenic Arabidopsis. Bot. Stud., 49: 109-117.
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  121. Chang, M.J., G.J. Huang, I.H. Lin, Y. L. Ho and S.S. Huang et al., 2008. Study on the antioxidant activities of the crude extracts from the roots of Arnebia euchroma and Lithospermum erythrorhizon. Mid-Taiwan J. Med., 13: 113-121.
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  122. Huang, G.J., M.J. Sheu, H.J. Chen, Y.S. Chang and Y.H. Lin, 2007. Inhibition of reactive nitrogen species in vivo and ex vivo by trypsin inhibitor from sweet potato 'Tainong 57' storage roots. J. Agric. Food Chem., 55: 6000-6006.
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  123. Huang, G.J., M.J. Sheu, H.J. Chen, Y.S. Chang and Y.H. Lin, 2007. Growth inhibition and induction of apoptosis in nb4 promyelocytic leukemia cells by trypsin inhibitor from sweet potato storage roots. J. Agric. Food Chem., 55: 2548-2553.
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  124. Huang, G.J., H.J. Chen, Y.S Chang, M.J Sheu and Y.H. Lin, 2007. Recombinant sporamin and its synthesized peptides with antioxidant activities in vitro. Bot. Stud., 48: 133-140.
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  125. Chang, H.Y., Y.L. Ho, M.J. Sheu, W.H. Pen, S.H. Wu, G.J. Huang and Y.S. Chang, 2007. Antioxidants and free radical scavenging activity of Phellinus merrillii extracts. Bot. Stud., 48: 407-417.
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  126. Chang, H.Y., W.H. Peng, M.J. Sheu, G.J. Huang and Z.C. Leu et al., 2007. Hepatoprotective and antioxidant effects of ethanol extract from Phellinus merrillii on carbon tetrachloride-induced liver damage. Am. J. Chin. Med., 35: 793-804.
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  127. Chang, H.Y., W.H. Peng, M.J. Sheu, G.J. Huang and Z.C. Leu et al., 2007. Analgesic and anti-inflammatory activities of Phellinus merrillii. Mid-Taiwan J. Med., 18: 76-82.
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  128. Chang, H.C., G.J. Huang, D.C. Agrawal, C.L. Kuo, C.R. Wu and H.S. Tsay, 2007. Antioxidant activities and polyphenol contents of six folk medicinal ferns used as Gusuibu. Botanical Stud., 48: 397-406.
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  129. Huang, G.J., W.C. Hou, H.J. Chen and Y.H. Lin, 2006. Sweet potato (Ipomoea batatas (L.)Lam. Tainong 57) storage root mucilage exibited angiotensin converting enzyme inhibitory activity in vitro. Bot. Bull. Acad. Sin., 47: 397-402.
  130. Huang, G.J., H.J. Chen, W.C. Hou and Y.H. Lin, 2006. Sweet potato (Ipomoea batatas [L.] Lam `Tainong 57`) storage roots mucilage with antioxidant activities in vitro. Food Chem., 98: 774-781.
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  131. Chen, H.J., G.J. Huang, W.C. Hou and Y.H. Lin, 2006. Molecular cloning and characterization of a granulin-containing cysteine protease SPCP3 from sweet potato (Ipomoea batatas) senescent leave. J. Plant Physiol., 163: 863-876.
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  132. Huang, G.J., H.J. Chen, W.C. Hou and Y.H. Lin, 2005. Expression and localization of protein disulfide isomerase cDNA from sweet potato (Ipomoea batatas [L.] Lam `Tainong 57`) storage roots. Plant Sci., 169: 776-784.
  133. Huang, G.J., H.J. Chen, C. Hou, T.E. Chen and Y.H. Lin, 2005. Isolation and characterization of cysteine proteinase cDNA from sweet potato (Ipomoea batatas [L.] Lam `Tainong 57`) storage roots. Plant Sci., 169: 423-431.
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  134. Huang, D.J., H.J. Chen, C.D. Lin and Y.H. Lin, 2005. Antioxidant and antiproliferative activities of water spinach (Ipomoea aquatica Forsk) constituents. Botanical Bull. Acad. Sinica, 46: 99-106.
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  135. Huang, G.J., H.J. Chen, W.C. Hou, C.D. Lin and Y.H. Lin, 2004. Active recombinant Thioredoxin h protein with antioxidant activities from sweet potato (Ipomoea batatas [L.] Lam Tainong 57) storage roots. J. Agric. Food Chem., 52: 4720-4724.
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  136. Huang, G.J., H.J. Chen, W.C. Hou and Y.H. Lin, 2004. Isolation and characterization of thioredoxin h cDNA from sweet potato (Ipomoea batatas [L.] Lam Tainong 57) storage roots. Plant Sci., 166: 515-523.
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  137. Huang, G.J., H.J. Chen, W.C. Hou and Y.H. Lin, 2004. In vitro reduction of trypsin inhibitor by purified NADPH/ Thioredoxin system from sprouts of sweet potato (Ipomoea batatas (L) Lam.) storage roots. Plant Sci., 166: 435-441.
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  138. Chen, T.E., G.J. Huang and Y.H. Lin, 2004. Isolation and characterization of a serine protease from the storage roots of sweet potato (Ipomoea batatas [L.] Lam). Plant Sci., 166: 1019-1026.
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  139. Chen, H.J., W.C. Hou, J.S. Liu, C.Y. Yang, G.J. Huang and Y.H. Lin, 2004. Molecular cloning and characterization of a cDNA encoding asparaginyl endopeptidase from sweet potato (Ipomoea batatas (L.) Lam.) senescent leaves. J. Exp. Bot., 55: 825-835.
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  140. Chen, H.J., W.C. Hou, C.Y. Yang, G.J. Huang, J.S. Liu and Y.H. Lin, 2003. Molecular cloning of two metallothionein-like protein genes with differential expression patterns from sweet potato (Ipomoea batatas) leaves. J. Plant Physiol., 5: 547-555.
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  141. Hou, W.C., G.J. Huang and Y.H. Lin, 2002. An aspartic type protease degrades trypsin inhibitors, the major root storage proteins of sweet potato (Ipomoea batatas (L.) Lam cv. Tainong 57). Bot. Bull. Acad. Sin., 4: 271-276.
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  142. Chen, W.L., G.J. Huang, P.H. Liu, H.L. Wang, J.C. Su and P.D. Lee, 2001. Purification and characterization of sucrose phosphate synthase from sweet potato tuberous roots. Bot. Bull. Acad. Sin., 42: 123-129.
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