Dr. Huan-Tsun Chang
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Dr. Huan-Tsun Chang

Professor
National Taiwan University, Taiwan

Highest Degree
PostDoc Fellow in Analytical Chemistry from University of Kentucky, USA

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Biography

Professor Huan-Tsung Chang graduated from Iowa State University, USA in 1994 and is a professor in the Department of Chemistry, National Taiwan University, Taiwan . His research focuses on preparation of functional gold nanoparticles for control of enzyme activity and for the detection of metal ions, proteins, and DNA. A number of fluorescent gold, silver and copper nanomaterials have been synthesized and used for sensitive and selective for cell imaging and for the detection of various analytes, including anions, metal ions, proteins, and DNA. Carbon nanodots and fluorescent polymeric spheres have been synthesized and applied for cell imaging in his group. Interestingly, he has demonstrated that carbon dots prepared from various precursors possess different optical properties and inhibit the growth of different cancer cells. In addition, he has developed nanoparticle based mass spectrometry techniques for the detection of polysaccharides, proteins, small analytes, and DNA. His research interests also include (1) nanomaterials based surface enhanced Raman scattering, nanomaterials based fuel cells, removal of contaminants using nanomaterials, quantum dots solar cells, and capillary electrophoresis.
Professor Chang is the author and coauthor of more than 270 scientific papers. He is a Fellow of the Royal Society of Chemistry.

Area of Interest:

Chemistry
100%
Mass Spectrometry
62%
Fuel Cells
90%
Green Chemistry
75%
Separation
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Weng, C.I., H.T. Chang, C.H. Lin, Y.W. Shen, B. Unnikrishnan, Y.J. Li and C.C. Huang, 2015. One-step synthesis of biofunctional carbon quantum dots for bacterial labeling. Bios. Bioelectron., 68: 1-6.
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  2. Roy, P., L.C. Ho, A.P. Periasamy, S.Y. Lin, M.F. Huang and H.T. Chang, 2015. Graphene-ZnO-Au nanocomposites based photocatalytic oxidation of benzoic acid. J. Spectrosc. Dyn., .
  3. Li, C.L., C.C. Huang, A.P. Periasamy, P. Roy, W.C. Wu, C.L. Hsu and H.T. Chang, 2015. Synthesis of photoluminescent carbon dots for the detection of cobalt ions. RSC Adv., 5: 2285-2291.
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  4. Ho, L.C., C.H. Hsu, C.M. Ou, C.W. Wang and T.P. Liu, et al., 2015. Unibody core-shell smart polymer as a theranostic nanoparticle for drug delivery and MR imaging. Biomater., 37: 436-446.
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  5. Chen. L.Y., C.W. Wang, Z. Yuan and H.T. Chang, 2015. Fluorescent gold nanoclusters: recent advances in sensing and imaging. Anal. Chem., 87: 216-219.
  6. Yuan, Z., Y.C. Chen, H.W. Li, and H.T. Chang, 2014. Fluorescent silver nanoclusters stabilized by DNA scaffolds. Chem. Commun., 50: 9800-9815.
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  7. Wang, C.W., W.T. Chen and H.T. Chang, 2014. Quantification of saccharides in honey samples through surface-assisted laser desorption/ionization mass spectrometry using HgTe nanostructures. J. Am. Soc. Mass Spectrom., 25: 1247-1252.
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  8. Wang, C.W. and H.T. Chang, 2014. Sensitive detection of platelet-derived growth factor through surface-enhanced raman scattering. Anal. Chem., 86: 7606-7611.
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  9. Wang, C.I., W.C. Wu, A.P. Periasamy and H.T. Chang, 2014. Sensitive and selective DNA probe based on “turn-on” photoluminescence of C-dots@ RGO. Anal. Bioanal. Chem., 406: 6917-6923.
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  10. Wang, C.I., W.C. Wu, A.P. Periasamy and H.T. Chang, 2014. Electrochemical synthesis of photoluminescent carbon nanodots from glycine for highly sensitive detection of hemoglobin. Green Chem., 16: 2509-2514.
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  11. Vedamalai, M., A.P. Periasamy, C.W. Wang, Y.T. Tseng, L.C. Ho, C.C. Shih and H.T. Chang, 2014. Carbon nanodots prepared from o-phenylenediamine for sensing of Cu 2+ ions in cells. Nanoscale, 6: 13119-13125.
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  12. Tseng, Y.T., Z. Yuan, Y.Y. Yang, C.C. Huang and H.T. Chang, 2014. Photoluminescent gold nanodots: role of the accessing ligands. RSC Adv., 4: 33629-33635.
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  13. So, Y.H., H.T. Chang, W.J. Chiu and C.C. Huang, 2014. Graphene oxide modified with aptamer-conjugated gold nanoparticles and heparin: a potent targeted anticoagulant. Biomater. Sci., 2: 1332-1337.
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  14. Shih, C.C., P.C. Chen, G.L. Lin, C.W. Wang and H.T. Chang, 2014. Optical and electrochemical applications of silicon-carbon dots/silicon dioxide nanocomposites. ACS nano, 9: 312-319.
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  15. Roy, P., A.P. Periasamy, C. Chuang, Y.R. Liou and Y.F. Chen, et al., 2014. Plant leaf-derived graphene quantum dots and applications for white LEDs. New J. Chem., 38: 4946-4951.
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  16. Ravindranath, R., P. Roy, A.P. Periasamy and H.T. Chang, 2014. Effects of deposited ions on the photocatalytic activity of TiO2-Au nanospheres. RSC Adv., 4: 57290-57296.
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  17. Periasamy, A.P., W.P. Wu, G.L. Lin, Z.Y. Shih, Z. Yang and H.T. Chang, 2014. Synthesis of Cu 9 S 8/carbon nanotube nanocomposites with high electrocatalytic activity for the oxygen reduction reaction. J. Mater. Chem. A, 2: 11899-11904.
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  18. Ma, J.Y., P.C. Chen and H.T. Chang, 2014. Detection of hydrogen sulfide through photoluminescence quenching of penicillamine-copper nanocluster aggregates. Nanotechnol., 25: 195502-195502.
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  19. Lina, T.E., C.L. Lia, Y.C. Shianga, C.L. Hsua, C.C. Huangb and H.T. Changa, 2014. Colorimetric detection of immunoglobulin G in plasma using functional iron oxide and gold nanoparticles. J. Spectrosc. Dyn., .
  20. Lin, G.L., A.P. Periasamy, Z.Y. Shih and H.T. Chang, 2014. Active and stable platinum/ionic liquid/carbon nanotube electrocatalysts for oxidation of methanol. Sci. Open Res., .
  21. Lien, C.W., Y.T. Tseng, C.C. Huang and H.T. Chang, 2014. Logic control of enzyme-like gold nanoparticles for selective detection of lead and mercury ions. Anal. chem., 86: 2065-2072.
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  22. Li, C.L., C.M. Ou, C.C. Huang, W.C. Wu and Y.P. Chen, et al., 2014. Carbon dots prepared from ginger exhibiting efficient inhibition of human hepatocellular carcinoma cells. J. Mater. Chem. B, 2: 4564-4571.
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  23. Lee, J.D., J. Cang, Y.C. Chen, W.Y. Chen, C.M. Ou and H.T. Chang, 2014. Detection of adenosine 5`-triphosphate by fluorescence variation of oligonucleotide-templated silver nanoclusters. Biosens. Bioelectron., 58: 266-271.
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  24. Hsu, K.I., C.W. Lien, C.H. Lin, H.T. Chang and C.C. Huang, 2014. Immobilization of iron hydroxide/oxide on reduced graphene oxide: peroxidase-like activity and selective detection of sulfide ions. RSC Adv., 4: 37705-37713.
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  25. Ho, L.C., C.W. Wang, P. Roy and H.T. Chang, 2014. Sensitive and selective gold nanomaterials based optical probes. J. Chin. Chem. Soc., 61: 163-174.
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  26. Chen, Y.N., P.C. Chen, C.W. Wang, Y.S. Lin, C.M. Ou, L.C. Ho and H.T. Chang, 2014. One-pot synthesis of fluorescent BSA-Ce/Au nanoclusters as ratiometric pH probes. Chem. Commun., 50: 8571-8574.
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  27. Chen, W.Y., C.C. Huang, L.Y. Chen and H.T. Chang, 2014. Self-assembly of hybridized ligands on gold nanodots: tunable photoluminescence and sensing of nitrite. Nanoscale, 6: 11078-11083.
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  28. Chen, P.C., P. Roy, L.Y. Chen, R. Ravindranath and H.T. Chang, 2014. Gold and silver nanomaterial-based optical sensing systems. Part. Part. Syst. Characteriz., 31: 917-942.
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  29. Chen, P.C., J.Y. Ma, L.Y. Chen, G.L. Lin, C.C. Shih, T.Y. Lin and H.T. Chang, 2014. Photoluminescent AuCu bimetallic nanoclusters as pH sensors and catalysts. Nanoscale, 6: 3503-3507.
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  30. Chen, L.Y., W.C. Wu and H.T. Chang, 2014. Functional microgels assisted tryptic digestion and quantification of cytochrome c through internal standard mass spectrometry. J. Am. Soc. Mass Spectrom., 25: 1944-1952.
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  31. Chen, G.H., W.Y. Chen, Y.C. Yen, C.W. Wang, H.T. Chang and C.F. Chen, 2014. Detection of mercury (II) ions using colorimetric gold nanoparticles on paper-based analytical devices. Anal. Chem., 86: 6843-6849.
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  32. Chang, H.Y., J. Cang, P. Roy, H.T. Chang, Y.C. Huang and C.C. Huang, 2014. Synthesis and antimicrobial activity of gold/silver-tellurium nanostructures. ACS Appl. Mater. Interfaces, 6: 8305-8312.
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  33. Yuan, Z., M. Peng, L. Shi, Y. Du and N. Cai, et al., 2013. Disassembly mediated fluorescence recovery of gold nanodots for selective sulfide sensing. Nanoscale, 5: 4683-4686.
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  34. Yeh, T.Y., C.I. Wang and H.T. Chang, 2013. Photoluminescent C-dots@ RGO for sensitive detection of hydrogen peroxide and glucose. Talanta, 115: 718-723.
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  35. Wang, C.W., Z.H. Lin, P. Roy and H.T. Chang, 2013. Detection of mercury ions using silver telluride nanoparticles as a substrate and recognition element through surface-enhanced Raman scattering. Front. Chem., .
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  36. Wang, C.I., Z. Yang, A.P. Periasamy and H.T. Chang, 2013. High-efficiency photochemical water splitting of CdZnS/CdZnSe nanostructures. J. Mater., .
  37. Wang, C.I., A.P. Periasamy and H.T. Chang, 2013. Photoluminescent C-dots@ RGO probe for sensitive and selective detection of acetylcholine. Anal. Chem., 85: 3263-3270.
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  38. Tsai, H.Y., Z.Y. Shih, Z.H. Lin and H.T. Chang, 2013. Te/Pt nanonetwork modified carbon fiber microelectrodes for methanol oxidation. Nanotechnol., 24: 195402-195402.
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  39. Tomalova, I., C.H. Lee, W.T. Chen, C.K. Chiang, H.T. Chang and J. Preisler, 2013. Analysis of the formation process of gold nanoparticles by surface-assisted laser desorption/ionization mass spectrometry. J. Am. Soc. Mass Spectrom., 24: 305-308.
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  40. Shih, Z.Y., Z.H. Lin and H.T. Chang, 2013. Se/Ru-Au nanocomposites provide enhanced-electroactivity in direct methanol fuel cells. Sci. Adv. Mater., 5: 1701-1708.
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  41. Shih, Z.Y., C.W. Wang, G. Xu and H.T. Chang, 2013. Porous palladium copper nanoparticles for the electrocatalytic oxidation of methanol in direct methanol fuel cells. J. Mater. Chem. A, 1: 4773-4778.
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  42. Shih, Z.Y., A.P. Periasamy, P.C. Hsu and H.T. Chang, 2013. Synthesis and catalysis of copper sulfide/carbon nanodots for oxygen reduction in direct methanol fuel cells. Appl. Catal. B Environ., 132: 363-369.
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  43. Shiang, Y.C., C.M. Ou, S.J. Chen, T.Y. Ou, H.J. Lin, C.C. Huang and H.T. Chang, 2013. Highly efficient inhibition of human immunodeficiency virus type 1 reverse transcriptase by aptamers functionalized gold nanoparticles. Nanoscale, 5: 2756-2764.
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  44. Roy, P., A.P. Periasamy, C.T. Liang and H.T. Chang, 2013. Synthesis of graphene-ZnO-Au nanocomposites for efficient photocatalytic reduction of nitrobenzene. Environ. Sci. technol., 47: 6688-6695.
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  45. Periasamy, A.P., J. Liu, H.M. Lin and H.T. Chang, 2013. Synthesis of copper nanowire decorated reduced graphene oxide for electro-oxidation of methanol. J. Mater. Chem. A, 1: 5973-5981.
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  46. Lin, Z.H., P. Roy, Z.Y. Shih, C.M. Ou and H.T. Chang, 2013. Synthesis of anatase Se/Te-TiO2 nanorods with dominant {100} facets: photocatalytic and antibacterial activity induced by visible light. Chem. Plus Chem., 78: 302-309.
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  47. Lien, C.W., Y.C. Chen, H.T. Chang and C.C. Huang, 2013. Logical regulation of the enzyme-like activity of gold nanoparticles by using heavy metal ions. Nanoscale, 5: 8227-8234.
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  48. Liao, Y.J., Y.C. Shiang, L.Y. Chen, C.L. Hsu, C.C. Huang and H.T. Chang, 2013. Detection of adenosine triphosphate through polymerization-induced aggregation of actin-conjugated gold/silver nanorods. Nanotechnol., 24: 444003-444003.
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  49. Jian, J.W., W.C. Chiu, H.T. Chang, P.H. Hsu and C.C. Huang, 2013. Fibrinolysis and thrombosis of fibrinogen-modified gold nanoparticles for detection of fibrinolytic-related proteins. Anal. Chim. Acta, 774: 67-72.
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  50. Huang, M.F. and H.T. Chang, 2013. Conformational dynamics of DNA bulge loops investigated by CE-LIF. Anal. Methods, 5: 2773-2777.
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  51. Hsu, P.C., P.C. Chen, C.M. Ou, H.Y. Chang and H.T. Chang, 2013. Extremely high inhibition activity of photoluminescent carbon nanodots toward cancer cells. J. Mater. Chem. B, 1: 1774-1781.
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  52. Ho, L.C., C.M. Ou, C.L. Li, S.Y. Chen, H.W. Li and H.T. Chang, 2013. Sensitive pH probes of retro-self-quenching fluorescent nanoparticles. J. Mater. Chem. B, 1: 2425-2432.
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  53. Chen, W.Y., l.y. Chen, C.M. Ou, C.C. Huang, S.C. Wei and H.T. Chang, 2013. Synthesis of fluorescent gold nanodot-liposome hybrids for detection of phospholipase C and its inhibitor. Anal. Chem., 85: 8834-8840.
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  54. Chen, W.T., M.F. Huang and H.T. Chang, 2013. Using surface-assisted laser desorption/ionization mass spectrometry to detect ss-and ds-oligodeoxynucleotides. J. Am. Soc. Mass Spectrom., 24: 877-883.
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  55. Chen, W.T. and H.T. Chang, 2013. Tea identification through surface-assisted laser desorption/ionization mass spectrometry. Int. J. Anal. Mass Spectrom. Chromatogr., 1: 11-21.
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  56. Chen, P.C., Y.N. Chen, P.C. Hsu, C.C. Shih and H.T. Chang, 2013. Photoluminescent organosilane-functionalized carbon dots as temperature probes. Chem. Commun., 49: 1639-1641.
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  57. Chen, P.C., T.Y. Yeh, C.M. Ou, C.C. Shih and H.T. Chang, 2013. Synthesis of aluminum oxide supported fluorescent gold nanodots for the detection of silver ions. Nanoscale, 5: 4691-4695.
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  58. Chen, P.C., C.K. Chiang and H.T. Chang, 2013. Synthesis of fluorescent BSA-Au NCs for the detection of Hg2+ ions. J. Nanopart. Res., 15: 1-10.
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  59. Chen, L.Y., C.M. Ou, W.Y. Chen, C.C. Huang and H.T. Chang, 2013. Synthesis of photoluminescent Au ND-PNIPAM hybrid microgel for the detection of Hg2+. ACS Appl. Mater. Interfaces, 5: 4383-4388.
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  60. Chen, L.Y., C.C. Huang, W.Y. Chen, H.J. Lin and H.T. Chang, 2013. Using photoluminescent gold nanodots to detect hemoglobin in diluted blood samples. Biosens. Bioelectron., 43: 38-44.
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  61. Chang, H.Y., H.T. Chang, Y.L. Hung, T.M. Hsiung, Y.W. Lin and C.C. Huang, 2013. Ligand effect on the luminescence of gold nanodots and its application for detection of total mercury ions in biological samples. RSC Adv., 3: 4588-4597.
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  62. Wang, C.I., W.T. Chen and H.T. Chang, 2012. Enzyme mimics of Au/Ag nanoparticles for fluorescent detection of acetylcholine. Anal. chem., 84: 9706-9712.
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  63. Wang, C.I., C.C. Huang, Y.W. Lin, W.T. Chen and H.T. Chang, 2012. Catalytic gold nanoparticles for fluorescent detection of mercury (II) and lead (II) ions. Anal. chim. acta, 745: 124-130.
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  64. Tsai, H.Y., Z.H. Lin and H.T. Chang, 2012. Tellurium-nanowire-coated glassy carbon electrodes for selective and sensitive detection of dopamine. Biosens. Bioelectron., 35: 479-483.
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  65. Shiang, Y.C., C.C. Huang, W.Y. Chen, P.C. Chen and H.T. Chang, 2012. Fluorescent gold and silver nanoclusters for the analysis of biopolymers and cell imaging. J. Mater. Chem., 22: 12972-12982.
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  66. Roy, P., Z.H. Lin, C.T. Liang and H.T. Chang, 2012. Synthesis of enzyme mimics of iron telluride nanorods for the detection of glucose. Chem. Commun., 48: 4079-4081.
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  67. Roy, P., Z.H. Lin, C.T. Liang and H.T. Chang, 2012. Iron telluride nanorods-based system for the detection of total mercury in blood. J. Hazard. Mater., 243: 286-291.
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  68. Liu, Y.C., H.T. Chang, C.K. Chiang and C.C. Huang, 2012. Pulsed-laser desorption/ionization of clusters from biofunctional gold nanoparticles: implications for protein detections. ACS Appl. Mater. Interfaces, 4: 5241-5248.
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  69. Lin, Z.H., Z.Y. Shih, P. Roy and H.T. Chang, 2012. Preparation of photocatalytic Au-Ag2Te nanomaterials. Chem. A Eur. J., 18: 12330-12336.
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  70. Lien, C.W., C.C. Huang and H.T. Chang, 2012. Peroxidase-mimic bismuth-gold nanoparticles for determining the activity of thrombin and drug screening. Chem. Commun., 48: 7952-7954.
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  71. Li, C.L., C.C. Huang, W.H. Chen, C.K. Chiang and H.T. Chang, 2012. Peroxidase mimicking DNA-gold nanoparticles for fluorescence detection of the lead ions in blood. Anal., 137: 5222-5228.
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  72. Huang, M.F. and H.T. Chang, 2012. Detection of carbohydrates using surface-assisted laser desorption/ionization mass spectrometry with HgTe nanostructures. Chem. Sci., 3: 2147-2152.
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  73. Hsu, P.C., Z.Y. Shih, C.H. Lee and H.T. Chang, 2012. Synthesis and analytical applications of photoluminescent carbon nanodots. Green Chem., 14: 917-920.
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  74. Hsu, C.L., S.C. Wei, J.W. Jian, H.T. Chang, W.H. Chen and C.C. Huang, 2012. Highly flexible and stable aptamer-caged nanoparticles for control of thrombin activity. RSC Adv., 2: 1577-1584.
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  75. Hsieh, Y.T., W.T. Chen, I. Tomalova, J. Preisler and H.T. Chang, 2012. Detection of melamine in infant formula and grain powder by surface-assisted laser desorption/ionization mass spectrometry. Rapid Commun. Mass Spectrom., 26: 1393-1398.
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  76. Chen, C.Y., Z.Y. Shih, Z. Yang and H.T. Chang, 2012. Carbon nanotubes/cobalt sulfide composites as potential high-rate and high-efficiency supercapacitors. J. Power Sour., 215: 43-47.
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  77. Yang, Z., C.Y. Chen, C.W. Liu and H.T. Chang, 2010. Electrocatalytic sulfur electrodes for CdS/CdSe quantum dot-sensitized solar cells. Chem. Commun., 46: 5485-5487.
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  78. Yang, Z and H.T. Chang, 2010. CdHgTe and CdTe quantum dot solar cells displaying an energy conversion efficiency exceeding 2%. Sol. Energy Mater. Sol. Cells, 94: 2046-2051.
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  79. Lin, Y.W., W.T. Chen and H.T. Chang, 2010. Exploring the interactions between gold nanoparticles and analytes through surface-assisted laser desorption/ionization mass spectrometry. Rapid Commun. Mass Spectrom., 24: 933-938.
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  80. Lee, K.H., M.F. Huang, C.W. Liu and H.T. Chang, 2010. Analysis of DNA complexes with small solutes by CE with LIF detection. Electrophoresis, 31: 1101-1107.
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  81. Lan, G.Y., Y.W. Lin, Z.H. Lin and H.T. Chang, 2010. Synthesis and characterization of Znx Hg1- x Se y S1- y quantum dots. J. Nanopart. Res., 12: 1377-1388.
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  82. Lan, G.Y., C.C. Huang and H.T. Chang, 2010. Silver nanoclusters as fluorescent probes for selective and sensitive detection of copper ions. Chem. Commun., 46: 1257-1259.
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  83. Kao, Y.Y., K.T. Liu, M.F. Huang, T.C. Chiu and H.T. Chang, 2010. Analysis of amino acids and biogenic amines in breast cancer cells by capillary electrophoresis using polymer solutions containing sodium dodecyl sulfate. J. Chromatogr., 1217: 582-587.
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  84. Huang, C.C., Y.L. Hung, Y.C. Shiang, T.Y. Lin, Y.S. Lin, C.T. Chen and H.T. Chang, 2010. Photoassisted synthesis of luminescent mannose-au nanodots for the detection of thyroglobulin in serum. Chem. Asian J., 5: 334-341.
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  85. Chiang, C.K., Z. Yang, Y.W. Lin, W.T. Chen, H.J. Lin and H.T. Chang, 2010. Detection of proteins and protein- ligand complexes using HgTe nanostructure matrixes in surface-assisted laser desorption/ionization mass spectrometry. Anal. Chem., 82: 4543-4550.
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  86. Chiang, C.K., Y.W. Lin, W.T. Chen and H.T. Chang, 2010. Accurate quantitation of glutathione in cell lysates through surface-assisted laser desorption/ionization mass spectrometry using gold nanoparticles. Nanomed. Nanotechnol. Biol. Med., 6: 530-537.
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  87. Chiang, C.K., N.C. Chiang, Z.H. Lin, G.Y. Lan, Y.W. Lin and H.T. Chang, 2010. Nanomaterial-based surface-assisted laser desorption/ionization mass spectrometry of peptides and proteins. J. Am. Soc. Mass Spectrom., 21: 1204-1207.
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  88. Chen, W.T., C.K. Chiang, Y.W. Lin and H.T. Chang, 2010. Quantification of captopril in urine through surface-assisted laser desorption/ionization mass spectrometry using 4-mercaptobenzoic acid-capped gold nanoparticles as an internal standard. J. Am. Soc. Mass Spectrom., 21: 864-867.
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  89. Chen, S.J., C.C. Huang and H.T. Chang, 2010. Enrichment and fluorescence enhancement of adenosine using aptamer-gold nanoparticles, PDGF aptamer, and Oligreen. Talanta, 81: 493-498.
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  90. Chen, C.K., C.C. Huang and H.T. Chang, 2010. Label-free colorimetric detection of picomolar thrombin in blood plasma using a gold nanoparticle-based assay. Biosens. Bioelectron., 25: 1922-1927.
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  91. Wu, S.F., T.C. Chiu, W.L. Ho and H.T. Chang, 2009. Combining capillary electrophoresis with laser-induced fluorescence detection for the analysis of Escherichia coli lysates. Electrophoresis, 30: 2397-2402.
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  92. Shiang, Y.C., C.C. Huang and H.T. Chang, 2009. Gold nanodot-based luminescent sensor for the detection of hydrogen peroxide and glucose. Chem. Commun., 2009: 3437-3439.
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  93. Liu, C.W., Y.W. Lin, C.C. Huang and H.T. Chang, 2009. Fluorescence detection of single-nucleotide polymorphisms using a thymidine-based molecular beacon. Biosens. Bioelectron., 24: 2541-2546.
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  94. Lin, Z.H., M.H. Lin and H.T. Chang, 2009. Facile synthesis of catalytically active platinum nanosponges, nanonetworks, and nanodendrites. Chem. Eur. J., 15: 4656-4662.
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  95. Lin, Y.W., C.W. Liu and H.T. Chang, 2009. DNA functionalized gold nanoparticles for bioanalysis. Anal. Methods, 1: 14-24.
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  96. Huang, C.C., T.Y. Lin, W.S. Yu, C.T. Chen and H.T. Chang, 2009. Time-resolved luminescence-based assay for thyroglobulin. J. Biomed. Nanotech., 5: 579-585.
    CrossRef  |  Direct Link  |  
  97. Chiang, N.C., C.K. Chiang, Z.H. Lin, T.C. Chiu and H.T. Chang, 2009. Detection of aminothiols through surface-assisted laser desorption/ionization mass spectrometry using mixed gold nanoparticles. Rapid Commun. Mass Spectrom., 23: 3063-3068.
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  98. Chiang, C.K., Y.W. Lin, C.C. Hu and H.T. Chang, 2009. Using electrospray ionization mass spectrometry to explore the interactions among polythymine oligonucleotides, ethidium bromide, and mercury ions. J. Am. Soc. Mass Spectrom., 20: 1834-1840.
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  99. Chen, Y.Y., H.T. Chang, Y.C. Shiang, Y.L. Hung, C.K. Chiang and C.C. Huang, 2009. Colorimetric assay for lead ions based on the leaching of gold nanoparticles. Anal. Chem., 81: 9433-9439.
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  100. Chen, C.K., K.T. Liu, T.C. Chiu and H.T. Chang, 2009. Separation of amino acids and amines by capillary electrophoresis using poly (ethylene oxide) solution containing cetyltrimethylammonium bromide. J. Chromatogr., 1216: 7576-7581.
    CrossRef  |  Direct Link  |  
  101. Huang, Y.F., H.T. Chang and W. Tan, 2008. Cancer cell targeting using multiple aptamers conjugated on nanorods. Anal. Chem., 80: 567-572.
    CrossRef  |  Direct Link  |  
  102. Huang, C.C., C.K. Chiang, Z.H. Lin, K.H. Lee and H.T. Chang, 2008. Bioconjugated gold nanodots and nanoparticles for protein assays based on photoluminescence quenching. Anal. Chem., 80: 1497-1504.
    CrossRef  |  Direct Link  |  
  103. Huang, C.C and H.T. Chang, 2008. Aptamer-based fluorescence sensor for rapid detection of potassium ions in urine. Chem. Commun., 2008: 1461-1463.
    CrossRef  |  Direct Link  |  
  104. Chiang, C.K., C.C. Huang, C.W. Liu and H.T. Chang, 2008. Oligonucleotide-based fluorescence probe for sensitive and selective detection of mercury (II) in aqueous solution. Anal. Chem., 80: 3716-3721.
    CrossRef  |  Direct Link  |  
  105. Yang, Z., Z.H. Lin, C.Y. Tang and H.T. Chang, 2007. Preparation and characterization of flower-like gold nanomaterials and iron oxide/gold composite nanomaterials. Nanotechnol., 18: 255606-255606.
    CrossRef  |  Direct Link  |  
  106. Yang, Z., T.C. Chiu and H.T. Chang, 2007. Preparation and characterization of different shapes of silver nanostructures in aqueous solution. Open Nanosci. J., 1: 5-12.
    CrossRef  |  Direct Link  |  
  107. Reddy, P., Y. Lin and H. Chang, 2007. Synthesis of novel benzothiazole compounds with an extended conjugated system. Arkivoc, 2007: 113-122.
    CrossRef  |  Direct Link  |  
  108. Liu, C.W and H.T. Chang, 2007. Protein-conjugated quantum dots for detecting trypsin and trypsin inhibitor through fluorescence resonance energy transfer. Open Anal. Chem. J., 1: 1-6.
    CrossRef  |  Direct Link  |  
  109. Lee, K.H., S.J. Chen, J.Y. Jeng, Y.C. Cheng, J.T. Shiea and H.T. Chang, 2007. Fluorescence and interactions with thiol compounds of Nile Red-adsorbed gold nanoparticles. J. Colloid Interface Sci., 307: 340-348.
    CrossRef  |  Direct Link  |  
  110. Lee, K.H., K.M. Huang, W.L. Tseng, T.C. Chiu, Y.W. Lin and H.T. Chang, 2007. Manipulation of the growth of gold and silver nanomaterials on glass by seeding approach. Langmuir, 23: 1435-1442.
    CrossRef  |  Direct Link  |  
  111. Lee, K.H., C.K. Chiang, Z.H. Lin and H.T. Chang, 2007. Determining enediol compounds in tea using surface-assisted laser desorption/ionization mass spectrometry with titanium dioxide nanoparticle matrices. Rapid commun. mass Spectrom., 21: 2023-2030.
    CrossRef  |  Direct Link  |  
  112. Lan, G.Y., Y.W. Lin, Y.F. Huang and H.T. Chang, 2007. Photo-assisted synthesis of highly fluorescent ZnSe (S) quantum dots in aqueous solution. J. Mater. Chem., 17: 2661-2666.
    CrossRef  |  Direct Link  |  
  113. Huang, Y.F., Y.W. Lin and H.T. Chang, 2007. Control of the surface charges of Au-Ag nanorods: Selective detection of iron in the presence of poly (sodium 4-styrenesulfonate). Langmuir, 23: 12777-12781.
    CrossRef  |  Direct Link  |  
  114. Huang, Y.F., K.M. Huang and H.T. Chang, 2007. Photoinduced Self-Assembly of Au-Ag-Hg trimetallic nanoparticles during their synthesis from gold seeds in glycine solution. J. Nanosci. Nanotechnol., 7: 3172-3179.
    CrossRef  |  Direct Link  |  
  115. Huang, Y.F and H.T. Chang, 2007. Analysis of adenosine triphosphate and glutathione through gold nanoparticles assisted laser desorption/ionization mass spectrometry. Anal. Chem., 79: 4852-4859.
    CrossRef  |  Direct Link  |  
  116. Huang, C.C., Z. Yang, K.H. Lee and H.T. Chang, 2007. Synthesis of Highly Fluorescent Gold Nanoparticles for Sensing Mercury(II). Angew. Chem., 119: 6948-6952.
    CrossRef  |  
  117. Huang, C.C., S.H. Chiu, Y.F. Huang and H.T. Chang, 2007. Aptamer-functionalized gold nanoparticles for turn-on light switch detection of platelet-derived growth factor. Anal. Chem., 79: 4798-4804.
    CrossRef  |  Direct Link  |  
  118. Huang, C.C and H.T. Chang, 2007. Parameters for selective colorimetric sensing of mercury (II) in aqueous solutions using mercaptopropionic acid-modified gold nanoparticles. Chem. Commun., 2007: 1215-1217.
    CrossRef  |  Direct Link  |  
  119. Hu, C.C., J.C. Lin, W.L. Tseng, M.F. Huang, T.C. Chiu and H.T. Chang, 2007. Analysis of dynamic and thermodynamic adsorption of nanoparticles on solid surfaces by dark-field light scattering measurements. J. Chin. Chem. Soc., 54: 869-878.
    CrossRef  |  Direct Link  |  
  120. Chiu, T.C., L.S. Huang, P.C. Lin, Y.C. Chen, Y.J. Chen, C.C. Lin and H.T. Chang, 2007. Nanomaterial based affinity matrix-assisted laser desorption/ionization mass spectrometry for biomolecules and pathogenic bacteria. Recent Pat. Nanotechnol., 1: 99-111.
    CrossRef  |  Direct Link  |  
  121. Chiu, T.C and H.T. Chang, 2007. Stacking and separation of fluorescent derivatives of amino acids by micellar electrokinetic chromatography in the presence of poly (ethylene oxide). J. Chromatogr. A, 1146: 118-124.
    CrossRef  |  Direct Link  |  
  122. Chen, C.L., P.L. Chang, S.S. Lee, F.C. Peng, C.H. Kuo and H.T. Chang, 2007. Analysis of magnolol and honokiol in biological fluids by capillary zone electrophoresis. J. Chromatogr., 1142: 240-244.
    CrossRef  |  Direct Link  |  
  123. Chang, P.L., W.S. Hsieh, C.L. Chiang, M.J. Tuohy and G.S. Hall et al., 2007. The hsp65 gene patterns of less common Mycobacterium and Nocardia spp. by polymerase chain reaction-restriction fragment length polymorphism analysis with capillary electrophoresis. Diagn. Microbiol. Infect. Dis., 58: 315-323.
    CrossRef  |  Direct Link  |  
  124. Chang, P.L., K.H. Lee, C.C. Hu and H.T. Chang, 2007. CE with sequential light-emitting diode-induced fluorescence and electro-chemiluminescence detections for the determination of amino acids and alkaloids. Electrophoresis, 28: 1092-1099.
    CrossRef  |  Direct Link  |  
  125. Yang, Z. and H.T. Chang, 2006. Anisotropic syntheses of boat-shaped core-shell Au-Ag nanocrystals and nanowires. Nanotechnol., 17: 2304-2310.
    CrossRef  |  
  126. Lin, Y.W., W.L. Tseng and H.T. Chang, 2006. Using a layer-by-layer assembly technique to fabricate multicolored-light-emitting films of CdSe@ CdS and CdTe quantum dots. Adv. Mater., 18: 1381-1386.
    CrossRef  |  Direct Link  |  
  127. Lin, Y.W., C.W. Liu and H.T. Chang, 2006. Synthesis and Properties of Water-Soluble Core-Shell-Shell Silica-CdSe/CdS-Silica Nanoparticles. J. Nanosci. Nanotechnol., 6: 1092-1100.
    CrossRef  |  
  128. Lin, Y.W. and H.T. Chang, 2006. Analysis of double-stranded DNA by capillary electrophoresis using poly(ethylene oxide) in the presence of hexadecyltrimethylammonium bromide. J. Chromatogr. A, 1130: 206-211.
    CrossRef  |  
  129. Huang, Y.F., Y.W. Lin and H.T. Chang, 2006. Growth of various Au-Ag nanocomposites from gold seeds in amino acid solutions. Nanotechnol., 17: 4885-4894.
    CrossRef  |  
  130. Huang, Y.F., M.M. Hsieh, W.L. Tseng and H.T. Chang, 2006. On-line concentration of microheterogeneous proteins by capillary electrophoresis using SDS and PEO as additives. J. Proteome Res., 5: 429-436.
    CrossRef  |  Direct Link  |  
  131. Huang, Y.F., K.M. Huang and H.T. Chang, 2006. Synthesis and characterization of Au core-Au-Ag shell nanoparticles from gold seeds: Impacts of glycine concentration and pH. J. Colloid Interface Sci. , 301: 145-154.
    CrossRef  |  
  132. Huang, Y.F., C.C. Huang, C.C. Hu and H.T. Chang, 2006. Capillary electrophoresis-based separation techniques for the analysis of proteins. Electrophoresis, 27: 3503-3522.
    CrossRef  |  
  133. Huang, Y.F. and H.T. Chang, 2006. Nile Red-Adsorbed Gold Nanoparticle Matrixes for Determining Aminothiols through Surface-Assisted Laser Desorption/Ionization Mass Spectrometry. Anal. Chem., 78: 1485-1493.
    CrossRef  |  
  134. Huang, C.C. and H.T. Chang, 2006. Selective Gold-Nanoparticle-Based “Turn-On” Fluorescent Sensors for Detection of Mercury(II) in Aqueous Solution. Anal. Chem., 78: 8332-8338.
    CrossRef  |  
  135. Hsieh, S.C., M.F. Huang, B.S. Lin and H.T. Chang, 2006. Determination of aristolochic acid in Chinese herbal medicine by capillary electrophoresis with laser-induced fluorescence detection. J. Chromatogr. A, 1105: 127-134.
    CrossRef  |  
  136. Hsieh, M.M., T.C. Chiu, W.L. Tseng and H.T. Chang, 2006. Analysis of Nucleic Acids and Proteins in Capillary Electrophoresis and Microchip Capillary Electrophoresis Using Polymers as Additives of the Background Electrolytes. Curr. Anal. Chem., 2: 17-33.
    CrossRef  |  
  137. Hsieh, M.M. and H.T. Chang, 2006. Impact of halides on the simultaneous separation of aromatic amines and their acidic metabolites by capillary electrophoresis with laser-induced native fluorescence detection under acidic conditions. J. Chromatogr. A, 1102: 302-308.
    CrossRef  |  
  138. Chiu, T.C., Y.W. Lin, Y.F. Huang and H.T. Chang, 2006. Analysis of biologically active amines by CE. Electrophoresis, 27: 4792-4807.
    CrossRef  |  
  139. Chang, P.L., T.C. Chiu and H.T. Chang, 2006. Stacking, derivatization, and separation by capillary electrophoresis of amino acids from cerebrospinal fluids. Electrophoresis, 27: 1922-1931.
    CrossRef  |  
  140. Chang, L.C., H.T. Chang and S.W. Sun, 2006. Cyclodextrin-modified microemulsion electrokinetic chromatography for separation of α-, γ-, δ-tocopherol and α-tocopherol acetate. J. Chromatogr. A, 1110: 227-234.
    CrossRef  |  
  141. Yang, Z., Y.W. Lin, W.L. Tseng and H.T. Chang, 2005. Impacts that pH and metal ion concentration have on the synthesis of bimetallic and trimetallic nanorods from gold seeds. J. Mater. Chem., 15: 2450-2454.
    CrossRef  |  Direct Link  |  
  142. Tseng, W.L., M.F. Huang, Y.F. Huang and H.T. Chang, 2005. Nanoparticle-filled capillary electrophoresis for the separation of long DNA molecules in the presence of hydrodynamic and electrokinetic forces. Electrophoresis, 26: 3069-3075.
    CrossRef  |  Direct Link  |  
  143. Tseng, W.L., K.H. Lee and H.T. Chang, 2005. Using nile red-adsorbed gold nanoparticles to locate glutathione within erythrocytes. Langmuir, 21: 10676-10683.
    CrossRef  |  Direct Link  |  
  144. Sreedhar, M., Y.W. Lin, W.L. Tseng and H.T. Chang, 2005. Determination of tertiary amines based on pH junctions and field amplification in capillary electrophoresis with electrochemiluminescence detection. Electrophoresis, 26: 2984-2990.
    CrossRef  |  Direct Link  |  
  145. Lu, M.J., T.C. Chiu, P.L. Chang, H.T. Ho and H.T. Chang, 2005. Determination of glycine, glutamine, glutamate, and γ-aminobutyric acid in cerebrospinal fluids by capillary electrophoresis with light-emitting diode-induced fluorescence detection. Anal. Chim. Acta, 538: 143-150.
    CrossRef  |  
  146. Lin, Y.W., M.M. Hsieh, C.P. Liu and H.T. Chang, 2005. Photoassisted Synthesis of CdSe and Core−Shell CdSe/CdS Quantum Dots. Langmuir, 21: 728-734.
    CrossRef  |  
  147. Lin, Y.W., M.F. Huang and H.T. Chang, 2005. Nanomaterials and chip-based nanostructures for capillary electrophoretic separations of DNA. Electrophoresis, 26: 320-330.
    CrossRef  |  
  148. Lin, Y.W. and H.T. Chang, 2005. Modification of poly(methyl methacrylate) microchannels for highly efficient and reproducible electrophoretic separations of double-stranded DNA. J. Chromatogr. A, 1073: 191-199.
    CrossRef  |  
  149. Kuo, I., Y.F. Huang and H.T. Chang, 2005. Silica nanoparticles for separation of biologically active amines by capillary electrophoresis with laser-induced native fluorescence detection. Electrophoresis, 26: 2643-2651.
    CrossRef  |  
  150. Huang, C.C., Y.F. Huang, Z. Cao, W. Tan and H.T. Chang, 2005. Aptamer-Modified Gold Nanoparticles for Colorimetric Determination of Platelet-Derived Growth Factors and Their Receptors. Anal. Chem., 77: 5735-5741.
    CrossRef  |  
  151. Hsieh, M.M. and H.T. Chang, 2005. Discontinuous electrolyte systems for improved detection of biologically active amines and acids by capillary electrophoresis with laser-induced native fluorescence detection. Electrophoresis, 26: 187-195.
    CrossRef  |  
  152. Chiu, T.C., S.H. Chiou, M.M. Hsieh, Y.T. Chen and H.T. Chang, 2005. Photosynthesis of Gold Nanoparticles in Presence of Proteins. J. Nanosci. Nanotechnol., 5: 2128-2132.
    CrossRef  |  
  153. Chang, S.Y., W.L. Tseng, S. Mallipattu and H.T. Chang, 2005. Determination of small phosphorus-containing compounds by capillary electrophoresis. Talanta, 66: 411-421.
    CrossRef  |  Direct Link  |  
  154. Chang, H.T., T.C. Chiu and C.C. Huang, 2005. Laser-Induced Fluorescence Detection for Capillary Electrophoresis. In: Encyclopedia of Chromatography, Cazes J. (Ed.). Marcel Dekker Inc., US, ISBN-13: 978-0824727871, pp 914-920.
  155. Huang, M.F., Y.C. Kuo, C.C. Huang and H.T. Chang, 2004. Separation of Long Double-Stranded DNA by Nanoparticle-Filled Capillary Electrophoresis. Anal. Chem., 76: 192-196.
    CrossRef  |  
  156. Huang, C.C., Z. Yang and H.T. Chang, 2004. Synthesis of Dumbbell-Shaped Au-Ag Core-Shell Nanorods by Seed-Mediated Growth under Alkaline Conditions. Langmuir, 20: 6089-6092.
    CrossRef  |  
  157. Huang, C.C., Z. Cao, H.T. Chang and W. Tan, 2004. Protein-Protein Interaction Studies Based on Molecular Aptamers by Affinity Capillary Electrophoresis. Anal. Chem., 76: 6973-6981.
    CrossRef  |  
  158. Huang, C.C., Y.F. Huang and H.T. Chang, 2004. Plasmon Absorption of Gold Nanoparticles in Linear Polymer Solutions. J. Nanosci. Nanotechnol., 4: 622-627.
    CrossRef  |  
  159. Ho, H.T., P.L. Chang, C.C. Hung and H.T. Chang, 2004. Capillary Electrophoretic Restriction Fragment Length Polymorphism Patterns for the Mycobacterial hsp65 Gene. J. Clin. Microbiol., 42: 3525-3531.
    CrossRef  |  Direct Link  |  
  160. Chiou, S.H., M.F. Huang and H.T. Chang, 2004. Separation of double-stranded DNA fragments by capillary electrophoresis: Impacts of poly(ethylene oxide), gold nanoparticles, ethidium bromide, and pH. Electrophoresis, 25: 2186-2192.
    CrossRef  |  
  161. Chen, S.J. and H.T. Chang, 2004. Nile Red-Adsorbed Gold Nanoparticles for Selective Determination of Thiols Based on Energy Transfer and Aggregation. Anal. Chem., 76: 3727-3734.
    CrossRef  |  
  162. Changa, H.T., Y.F. Huanga, S.H. Chiou, T.C. Chiu and M.M. Hsieh, 2004. Advanced Capillary and Microchip Electrophoretic Techniques for Proteomics. Curr. Proteomics, 1: 325-347.
    CrossRef  |  
  163. Chang, P.L., I.T. Kuo, T.C. Chiu and H.T. Chang, 2004. Fast and sensitive diagnosis of thalassemia by capillary electrophoresis. Anal. Bioanal. Chem., 379: 404-404.
    CrossRef  |  
  164. Lin, Y.W., T.C. Chiu and H.T. Chang, 2003. Laser-induced fluorescence technique for DNA and proteins separated by capillary electrophoresis. J. Chromatogr. B, 793: 37-48.
    CrossRef  |  
  165. Lin, Y.W., M.J. Huang and H.T. Chang, 2003. Analysis of double-stranded DNA by microchip capillary electrophoresis using polymer solutions containing gold nanoparticles. J. Chromatogr. A, 1014: 47-55.
    CrossRef  |  
  166. Lin, Y.W., C.C. Huang and H.T. Chang, 2003. Capillary electrophoretic separation of dsDNA under nonuniform electric fields. Anal. Bioanal. Chem., 376: 379-383.
    CrossRef  |  
  167. Kuo, I., T.C. Chiu and H.T. Chang, 2003. On-column concentration and separation of double-stranded DNA by gradient capillary electrophoresis. Electrophoresis, 24: 3339-3347.
    CrossRef  |  
  168. Huang, Y.F., C.C. Huang and H.T. Chang, 2003. Exploring the Activity and Specificity of Gold Nanoparticle-Bound Trypsin by Capillary Electrophoresis with Laser-Induced Fluorescence Detection. Langmuir, 19 : 7498-7502.
    CrossRef  |  
  169. Huang, M.F., C.C. Huang and H.T. Chang, 2003. Improved separation of double-stranded DNA fragments by capillary electrophoresis using poly(ethylene oxide) solution containing colloids. Electrophoresis, 24: 2896-2902.
    CrossRef  |  
  170. Huang, M.F. and H.T. Chang, 2003. Indirect Fluorescence of Amines in Capillary Electrophoresis, Using Cresyl Violet. J. Liq. Chromatogr. Related Technol., 26: 3387-3400.
    CrossRef  |  
  171. Chiu, T.C., Y.W. Lin, C.C. Huang, A. Chrambach and H.T. Chang, 2003. A simple, rapid, and sensitive method for analysis of SYPRO Red labeled sodium dodecyl sulfate-protein complexes by capillary electrophoresis with laser-induced fluorescence. Electrophoresis, 24: 1730-1736.
    CrossRef  |  
  172. Chen, S.J., M.J. Chen and H.T. Chang, 2003. Light-emitting diode-based indirect fluorescence detection for simultaneous determination of anions and cations in capillary electrophoresis J. Chromatogr. A, 1017: 215-224.
    CrossRef  |  
  173. Chang, H.T. and T.C. Chiu, 2003. On-column concentration techniques in capillary electrophoresis using polymer solutions. GIT Lab. J. Eur., 7: 64-65.
  174. Wang, S.J., W.L. Tseng, Y.W. Lin and H.T. Chang, 2002. On-line concentration of trace proteins by pH junctions in capillary electrophoresis with UV absorption detection. J. Chromatogr. A, 979: 261-270.
    CrossRef  |  Direct Link  |  
  175. Tseng, W.L., Y.W. Lin, K.C. Chen and H.T. Chang, 2002. DNA analysis on microfabricated electrophoretic devices with bubble cells. Electrophoresis, 23: 2477-2484.
    CrossRef  |  
  176. Tseng, W.L., Y.W. Lin and H.T. Chang, 2002. Improved separation of microheterogeneities and isoforms of proteins by capillary electrophoresis using segmental filling with SDS and PEO in the background electrolyte. Anal. Chem., 74: 4828-4834.
    CrossRef  |  Direct Link  |  
  177. Tseng, W.L. and H.T. Chang, 2002. Amplification of small analytes in polymer solution by capillary electrophoresis. Electrophoresis, 23: 1633-1641.
  178. Radko, S.P., H.T. Chen, S.F. Zakharov, L. Bezrukov, A.L. Yergey, N.E. Vieira and A. Chrambach, 2002. Electroelution without gel sectioning of proteins from sodium dodecyl sulfate-polyacrylamide gel electrophoresis: Fluorescent detection, recovery, isoelectric focusing and matrix assisted laser desorption/ionization-time of flight of the electroeluate. Electrophoresis, 23: 985-992.
    CrossRef  |  
  179. Huang, C.C., T.C. Chiu and H.T. Chang, 2002. Effects of metal ions on concentration of DNA in high-conductivity media by capillary electrophoresis. J. Chromatogr. A, 966: 195-203.
    CrossRef  |  
  180. Hsieh, M.M., P.L. Chang and H.T. Chang, 2002. The impact of a plug of salts on the analysis of large volumes of dsDNA by capillary electrophoresis. Electrophoresis, 23: 2388-2393.
    CrossRef  |  
  181. Chiu, T.C., M.F. Huang, C.C. Huang, M.M. Hsieh and H.T. Chang, 2002. Indirect fluorescence of aliphatic carboxylic acids in nonaqueous capillary electrophoresis using merocyanine 540. Electrophoresis, 23: 449-455.
    CrossRef  |  
  182. Chiu, T.C. and H.T. Chang, 2002. Comparison of the separation of large DNA fragments in the presence and absence of electroosmotic flow at high pH. J. Chromatogr. A, 979: 299-306.
    CrossRef  |  
  183. Tseng, W.L., H.T. Chang, S.M. Hsu, R.J. Chen and S. Lin, 2002. Immunoaffinity capillary electrophoresis: Determination of affinity and stoichiometry for antibody-antigen interaction kinetics. Electrophoresis, 23: 836-846.
  184. Tseng, W.L., T.C. Chiu, J.M. Weng and H.T. Chang, 2001. Analysis of albumins, using albumin blue 580, by capillary electrophoresis and laser-induced fluorescence. J. Liquid Chromatogr. Related Technol., 24: 2971-2982.
    CrossRef  |  Direct Link  |  
  185. Tseng, W.L., M.M. Hsieh, S.J. Wang, C.C. Huang, Y.C., Lin, P.L. Chang and H.T. Chang, 2001. Analysis of large-volume DNA markers and polymerase chain reaction products by capillary electrophoresis in the presence of electroosmotic flow. J. Chromatogr. A, 927: 179-190.
    CrossRef  |  Direct Link  |  
  186. Tseng, W.L. and H.T. Chang, 2001. Regulation of electroosmotic flow and electrophoretic mobility of proteins for concentration without desalting. J. Chromatogr. A, 924: 93-101.
    CrossRef  |  Direct Link  |  
  187. Tseng, W.L. and H.T. Chang, 2001. A new strategy for optimizing sensitivity, speed and resolution in capillary electrophoretic separation of DNA. Electrophoresis, 22: 763-770.
    CrossRef  |  Direct Link  |  
  188. Huang, M.F., C.E. Hsu, W.L. Tseng, Y.C. Lin and H.T. Chang, 2001. Separation of dsDNA in the presence of electroosmotic flow under discontinuous conditions. Electrophoresis, 22: 2281-2290.
  189. Hsieh, M.M., Y.C. Kuo, P.L. Tsai and H.T. Chang, 2001. Optimizing separation conditions for polycyclic aromatic hydrocarbons in micellar electrokinetic chromatography. J. Chromatogr. A, 924: 397-405.
    CrossRef  |  
  190. Chiu, T.C., Y.C. Lin and H.T. Chang, 2001. Maximization of injection volumes for DNA analysis in capillary electrophoresis. Electrophoresis, 22: 4328-4332.
    CrossRef  |  
  191. Chang, H.T., A.L. Yergey and A. Chrambach, 2001. Electroelution of proteins from bands in gel electrophoresis without gel sectioning for the purpose of protein transfer into mass spectrometry: Elements of a new procedure. Electrophoresis, 22: 394-398.
    CrossRef  |  
  192. Buzas, Z., H.T. Chang, N.E. A.L. Yergey, M. Stastna and A. Chrambach, 2001. Direct vertical electroelution of protein from a PhastSystem band for mass spectrometric identification at the level of a few picomoles. Proteomics, 1: 691-698.
    CrossRef  |  
  193. Tseng, W.L., M.M. Hsieh, S.J. Wang and H.T. Chang, 2000. Effect of ionic strength, pH and polymer concentration on the separation of DNA fragments in the presence of electroosmotic flow. J. Chromatogr. A, 894: 219-230.
    CrossRef  |  Direct Link  |  
  194. Tseng, W.L. and H.T. Chang, 2000. On-line concentration and separation of proteins by capillary electrophoresis using polymer solutions. Anal. Chem., 72: 4805-4811.
    CrossRef  |  Direct Link  |  
  195. Huang, M.F. and H.T. Chang, 2000. Capillary Electrophoretic Separation of DNA Fragments Under Stepwise Changes of Polymer Solutions. Instrum. Sci. Technol., 28: 387-401.
    CrossRef  |  
  196. Hsieh, M.M., Y.C. Kuo, M.J. Lyu and H.T. Chang, 2000. Dynamic modification of the capillary wall for electrophoretic separations of small ions. J. Chromatogr. A, 898: 133-139.
    CrossRef  |  
  197. Hsieh, M.M., W.L. Tseng and H.T. Chang, 2000. On-column preconcentration and separation of DNA fragments using polymer solutions in the presence of electroosmotic flow. Electrophoresis, 21: 2904-2910.
    CrossRef  |  Direct Link  |  
  198. Chang, H.T., H.S. Chen, M.M. Hsieh and W.L. Tseng, 2000. Electrophoretic separation of DNA in the presence of electroosmotic flow. Rev. Anal. Chem., 19: 45-74.
  199. Chen, M.J., H.S. Chen, C.Y. Lin and H.T. Chang, 1999. Indirect detection of organic acids in non-aqueous capillary electrophoresis J. Chromatogr. A, 853: 171-180.
    CrossRef  |  
  200. Chen, H.S. and H.T. Chang, 1999. Stepwise capillary electrophoretic separation of DNA fragments using poly(ethylene oxide) solutions in the presence of electroosmotic flow. J. Chromatogr. A, 853: 337-347.
    CrossRef  |  
  201. Chen, H.S. and H.T. Chang, 1999. Electrophoretic Separation of Small DNA Fragments in the Presence of Electroosmotic Flow Using Poly(ethylene oxide) Solutions. Anal. Chem., 71: 2033-2036.
    CrossRef  |  
  202. Zakharov, S.F., S.H. Kwok, H. Sokoloff, H.T. Chang, S.P. Radko and A. Chrambach, 1998. The band areas of proteins determined by fluorescent scanning in the commercial automated gel electrophoresis apparatus. Electrophoresis, 19: 1625-1630.
    CrossRef  |  
  203. Hsieh, M.M. and H.T. Chang, 1998. Dynamic control for ultra-fast separations of organic acids in capillary zone electrophoresis: A new direction to improve resolution. J. Chromatogr. A, 817: 129-137.
    CrossRef  |  
  204. Hsieh, M.M. and H.T. Chang, 1998. Dynamic control for the separation of organic acids in capillary electrophoresis. J. Chromatogr. A, 793: 145-152.
    CrossRef  |  
  205. Chen, H.S. and H.T. Chang, 1998. Capillary electrophoretic separation of 1 to 10 kbp sized dsDNA using poly(ethylene oxide) solutions in the presence of electroosmotic counterflow. Electrophoresis, 19: 3149-3153.
    CrossRef  |  
  206. Chang, H.T., H.S. Chen and R. Lee, 1998. Dynamic control and indirect absorption detection for high-speed capillary electrophoretic separation of organic acids. J. Chromatogr. A, 800: 339-344.
    CrossRef  |  
  207. Chang, H.T., N. Chen, J.V. Sullivan and A. Chrambach, 1997. Preparative electrophoresis in a concentrated polymer solution: Automated procedure for microsome isolation. Anal. Biochem., 247: 111-114.
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  208. Zakharov, S.F., H.T. Chang and A. Chrambach, 1996. Reproducibility of mobility in gel electrophoresis. Electrophoresis, 17: 84-90.
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  209. Chang, H.T., S.F. Zakharov and A. Chrambach, 1996. Separation and isolation of subcellular-size particles by electrophoresis in polymer solution using the commercial scanning apparatus. Electrophoresis, 17: 776-780.
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  210. Chang, H.T. and A. Chrambach, 1996. Application of gels of 0.5 mm thickness to electrophoresis in the automated HPGE-1000 apparatus: Improved resolution. Electrophoresis, 17: 80-83.
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  211. Chang, H.T. and E.S. Yeung, 1995. Poly(ethyleneoxide) for high resolution and high-speed separation of DNA by capillary electrophoresis. J. Chromatogr. B: Biomed. Sci. Appl., 669: 113-123.
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  212. Chang, H.T. and E.S. Yeung, 1995. Dynamic control to improve the separation performance in capillary electrophoresis. Electrophoresis, 16: 2069-2073.
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  213. Chang, H.T. and E.S. Yeung, 1995. Determination of catecholamines in single adrenal medullary cells by capillary electrophoresis and laser-induced native fluorescence. Anal. Chem., 67: 1079-1083.
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  214. Chang, H.T. and A. Chrambach, 1995. Horizontal gel electrophoresis with sample volumes up to 1.5 mL, using a discontinuous buffer system and automated apparatus. Electrophoresis, 16: 952-957.
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  215. Chang, H.T. and A. Chrambach, 1995. Dispersion coefficients of a protein and DNA fragment in polyacrylamide gel electrophoresis as a function of parameters defining the effective gel pore size and particle size. Electrophoresis, 16: 895-898.
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  216. Aldroubi, A., H.T. Chang, S.F. Zakharov and A. Chrambach, 1995. Determination of Optimally Resolving Gel Concentration and Migration Time (Path) in Gel Electrophoresis. Anal. Biochem., 231: 432-436.
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  217. Chang, H.T. and A. Chrambach, 1994. Feasibility of electrophoresis of a subcellular-sized particle in polymer solutions, using automated horizontal gel apparatus. Appl. Theor. Electrophoresis, 5: 73-77.
  218. Huan-Tsung, C. and E.S. Yeung, 1993. Voltage programming in capillary zone electrophoresis. J. Chromatogr. A, 632: 149-155.
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  219. Chang, H.T. and E.S. Yeung, 1993. Self-regulating dynamic control of electroosmotic flow in capillary electrophoresis. Anal. Chem., 65: 650-652.
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  220. Chang, H.T. and E.S. Yeung, 1993. Oncolumn digestion of protein for peptide mapping by capillary zone electrophoresis with laser-induced native fluorescence detection. Anal. Chem., 65: 2947-2951.
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  221. Chang, H.T. and E.S. Yeung, 1992. Optimization of selectivity in capillary zone electrophoresis via dynamic pH gradient and dynamic flow gradient. J. Chromatogr. A, 608: 65-72.
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  222. Chuen-Ying, L., C. Huan-Tsung and H. Cho-Chun, 1990. Complexation reactions in a heterogeneous system. Inorg. Chim. Acta, 172: 151-158.
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  223. Liu, C.Y., H.T. Chang and L.J. Uang, 1987. Determination of microamounts of iron by hydroxamate resin colorimetry. Original Pap. Inorg. Anal., 328: 61-63.
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