Dr. Xin Chen
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Dr. Xin Chen

Professor
Changzhou University, China

Highest Degree
Ph.D. in Synthetic Organic Chemistry from Lanzhou Univeristy, China

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Area of Interest:

Chemistry
100%
Crystal Engineering
62%
Organic Chemistry
90%
Medicinal Chemistry
75%
Synthesis
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zhang, C., X. Wu, Y. Li, C. Liang and Y. Che et al., 2013. Synthesis and bioactivity of novel inhibitors for type III secretion system of Pseudomonas aeruginosa PAO1. Chin. J. Org. Chem., 33: 1309-1318.
  2. Yue, F., X. Yu, Y. Luo, J. Yang, X. Chen and H. Zhang, 2013. A rare 4-connected neb topological framework based on Zn(II). J. Coord. Chem., 66: 2843-2851.
    CrossRef  |  
  3. Wang, J., S. Ahn, A.W. Kahsai, R. Liu and J. Ren et al., 2013. Synthesis of β2-AR agonist BI-167107. Chin. J. Org. Chem., 33: 634-639.
  4. Ren, J., J. Zhao, Y.S. Zhou, X.H. Liu, X. Chen and K. Hu, 2013. Synthesis and antitumor activity of novel 4-aminoquinoline derivatives. Med. Chem. Res., 22: 2855-2861.
    CrossRef  |  
  5. Luo, Y.H., F.X. Yue, X.Y. Yu, X. Chen and H. Zhang, 2013. Coordination polymers of lanthanide complexes with benzene dicarboxylato ligands. Cryst. Eng. Comm., 15: 6340-6348.
    CrossRef  |  
  6. Luo, Y.H., F.X. Yue, X.Y. Yu, L.L. Gu, H. Zhang and X. Chen, 2013. A series of entangled ZnII/CdII coordination polymers constructed from 1,3,5-benzenetricarboxylate acid and flexible triazole ligands. Cryst. Eng. Comm., 15: 8116-8124.
    CrossRef  |  
  7. Li, Z.Y., H.Z. Ma, C. Han, H.T. Xi, Q. Meng, X. Chen and X.Q. Sun, 2013. Synthesis of isothiocyanates by reaction of amines with phenyl chlorothionoformate via one-pot or two-step process. Synthesis, 45: 1667-1674.
    CrossRef  |  
  8. Khokhani, D., C. Zhang, Y. Li, Q. Wang and Q. Zeng et al., 2013. Discovery of plant phenolic compounds that act as type III secretion system inhibitors or inducers of the fire blight pathogen, Erwinia amylovora. Applied Environ. Microb., 79: 5424-5436.
    CrossRef  |  
  9. Hu, K., Y.J. Qi, J. Zhao, H.F. Jiang, X. Chen and J. Ren, 2013. Synthesis and biological evaluation of sulforaphane derivatives as potential antitumor agents. Eur. J. Med. Chem., 64: 529-539.
  10. Guo, S.Q., D. Tian, Y.H. Luo, X. Chen and H. Zhang, 2013. Two unusual 12-connected metalorganic coordination polymers with fcu net. J. Solid State Chem., 205: 110-115.
    CrossRef  |  
  11. Zheng, X., S.Q. Guo, X.Y. Yu, J.K. Hu, Y.H. Luo, H. Zhang and X. Chen, 2012. Two zinc(II) coordination polymers based on a benzenedicarboxylic acid derivative: Synthesis, crystal structures and luminescent properties. Inorg. Chem. Commun., 18: 29-33.
    CrossRef  |  
  12. Yamazaki, A., J. Li, Q. Zeng, D. Khokhani and W.C. Hutchins et al., 2012. Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. Antimicrob. Agents Chemother., 56: 36-43.
    Direct Link  |  
  13. Ren, J., H.J. Xu, H. Cheng, W.Q. Xin, X. Chen and K. Hu, 2012. Synthesis and antitumor activity of formononetin nitrogen mustard derivatives. Eur. J. Med. Chem., 54: 175-187.
    CrossRef  |  
  14. Ren, J., H. Cheng, W.Q. Xin, X. Chen and K. Hu, 2012. Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells. Oncol. Rep., 28: 1719-1726.
    CrossRef  |  
  15. Hu, K., L. Wu, W.Q. Xin, X. Chen and J. Ren, 2012. Synthesis and biological evaluation of novel 4β-(1,3,4-oxadiazole-2-amino)-podophyllotoxin derivatives. Bioorg. Med. Chem. Lett., 22: 4778-4782.
    CrossRef  |  
  16. Chen, X., X. Zhang, Y. Lu, J.Y. Shim, S. Sang, Z. Sun and X. Chen, 2012. Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol. Nutr. Cancer, 64: 1211-1218.
    CrossRef  |  
  17. Chen, T.L., X.Y. Yu, X. Zhao, Y.H. Luo, J.J. Yang, H. Zhang and X. Chen, 2012. Syntheses, structures and luminescence properties of two series of 3D lanthanide coordination polymers based on benzimidazole-5,6-dicarboxylic acid and oxalate. Inorg. Chem. Commun., 18: 74-77.
    CrossRef  |  
  18. Tovmasyan, A., Z. Rajic, I. Spasojevic, J.S. Reboucas and X. Chen et al., 2011. Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins. J. Chem. Soc. Dalton Trans., 40: 4111-4121.
    CrossRef  |  
  19. Nguyen, B.D., D.F. Cunningham, X. Liang, X. Chen and E.J. Toone et al., 2011. Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis. Proc. Natl. Acad. Sci. USA, 108: 10284-10289.
    CrossRef  |  
  20. Liang, X., C.J. Lee, X. Chen, H.S. Chung and D. Zeng et al., 2011. Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold. Bioorg. Med. Chem., 19: 852-860.
    CrossRef  |  
  21. Lee, C., X. Liang, X. Chen, D. Zeng and S.H. Joo et al., 2011. Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chem. Biol., 18: 38-47.
    CrossRef  |  
  22. Chen, X., Z. Li, X. Sun, H. Ma, X. Chen, J. Ren and K. Hu, 2011. New method for synthesis of sulforaphane and the related isothiocyanates. Synthesis, 2011: 3991-3996.
    CrossRef  |  
  23. Warren, W.S., E. Jenista, R.T. Branca and X. Chen, 2009. Increasing hyperpolarized spin lifetimes through true singlet eigenstates. Science, 323: 1711-1714.
    CrossRef  |  
  24. Li, Y., Q. Peng, D. Selimi, Q. Wang, A. Charkowski, X. Chen and C.H. Yang, 2009. The plant phenolic compound p-coumaric acid represses gene expression in the Dickeya dadantii type III secretion system. Applied Environ. Microb., 75: 1223-1228.
  25. Arnold, J.J., Y. Choksi, X. Chen, A. Shimazaki and J. Hatten et al., 2009. Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits. J. Ocul. Pharmacol. Ther., 25: 179-186.
    CrossRef  |  
  26. Aldrich, J.R., A.K. Hrimian, X. Chen and M.J. Camp, 2009. Semiochemically based monitoring of the invasion of the brown marmorated stink bug and unexpected attraction of the native green stink bug (Heteroptera: Pentatomidae) in Maryland. Florida Entomologist, 92: 483-491.
    Direct Link  |  
  27. Ward, W.C., E.C. Lamb, D. Gooden, X. Chen, D.J. Burinsky and J.D. Simon, 2008. Quantification of naturally occurring pyrrole acids in melanosomes. Photochem. Photobiol., 84: 700-705.
    CrossRef  |  
  28. McBrien, H.L., J.G. Millar, L. Gottlieb, X. Chen and R.E. Rice, 2001. Male-produced sex attractant pheromone of the green stink bug, Acrosternum hilare (Say). J. Chem. Ecol., 27: 1821-1839.
    CrossRef  |  
  29. McElfresh, J.S., X. Chen, D.W. Ross and J.G. Millar, 2000. Sex pheromone blend of the pandora moth Coloradia Pandora, an outbreak pest in pine forests in the western United States. Can. Entomol., 132: 775-787.
  30. Chen, X., L. Gottlieb and J.G. Millar, 2000. Highly stereoselective syntheses of the sex pheromone components of the southern green stink bug Nezara viridula (L.) and the green stink bug Acrosternum hilare (Say). Synthesis, 2000: 269-272.
    CrossRef  |  
  31. Chen, X. and J.G. Millar, 2000. Preparative scale syntheses of isomerically pure (10E,12E,14Z)- and ((10E,12E,14E)-hexadeca-10,12,14-trienals, sex pheromone components of Manduca sexta. Synthesis, 2000: 113-118.
    CrossRef  |