Dr. Ying Peng
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Dr. Ying Peng

Professor
Sun Yat-Sen University, China

Highest Degree
Ph.D. in Neurology from Sun Yat-Sen University of Medical Sciences, China

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Area of Interest:

Biomedical Sciences
100%
Neurological Pain
62%
Toxic Encephalopathy
90%
Gene Therapy
75%
Oncology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yue, P.J., L. He, Y. Li, Q.Y. Shen and M. Li et al., 2013. Preclinical safety evaluation of rAd5-hTERTC27 by intravenous injection. Regul. Toxicol. Pharmacol., 67: 53-62.
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  2. Qiu, S., S. Lin, D. Hu, Y. Feng, Y. Tan and Y. Peng, 2013. Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients. J. Trans. Med., Vol. 11. 10.1186/1479-5876-11-10.
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  3. Qiu, S., D. Huang, F. Li, D. Yin, H.F. Kung and Y. Peng, 2013. Suppression of tumorigenicity by MicroRNA-138 through inhibition of EZH2-CDK4/6-pRb-E2F1 signal loop in glioblastoma multiforme. Biochim. Biophys. Acta (BBA)-Mol. Basis Dis., 1832: 1697-1707.
    CrossRef  |  
  4. Liu, X., J. Lu, M.L. He, Z. Li and B. Zhang et al., 2013. Antitumor effects of interferon-alpha on cell growth and metastasis in human nasopharyngeal carcinoma. Curr. Cancer Drug Targets, 12: 561-570.
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  5. Li, Y., X. Shi, X. Rong, Y. Peng and Y. Tang, 2013. Neurosurgery and prognosis in patients with radiation-induced brain injury after nasopharyngeal carcinoma radiotherapy: A follow-up study. Radiat. Oncol., Vol. 8. 10.1186/1748-717X-8-88.
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  6. Li, H., R. Pan, H. Wang, X. Rong and Z. Yin et al., 2013. Clipping versus coiling for ruptured intracranial aneurysms: A systematic review and meta-analysis. Stroke, 44: 29-37.
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  7. Li, D., X.P. Li, H.X. Wang, Q.Y. Shen and X.P. Li et al., 2013. VEGF induces angiogenesis in a zebrafish embryo glioma model established by transplantation of human glioma cells. Oncol. Rep., 28: 937-942.
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  8. Li, C., X. Li, Q. Shen, Y. Li and L. He et al., 2013. Critical role of matrix metalloproteinase-9 in acute cold exposure-induced stroke in renovascular hypertensive rats. J. Stroke Cerebrovasc. Dis., 22: 477-485.
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  9. He, L., M. Li, X.H. Long, X.P. Li and Y. Peng, 2013. A case of Hashimoto's encephalopathy misdiagnosed as viral encephalitis. Am. J. Case Rep., 14: 366-369.
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  10. He, L., H.X. Gong, X.P. Li, Y.D. Wang and Y. Li et al., 2013. Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice. Oncol. Lett., 6: 748-752.
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  11. Zhao, J., L. Li, Z. Pei, C. Li and H. Wei et al., 2012. Peroxisome proliferator activated receptor (PPAR)-γ co-activator 1-α and hypoxia induced factor-1α mediate neuro- and vascular protection by hypoxic preconditioning in vitro. Brain Res., 1447: 1-8.
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  12. Tang, Y., D. Luo, X. Rong, X. Shi and Y. Peng, 2012. Psychological disorders, cognitive dysfunction and quality of life in nasopharyngeal carcinoma patients with radiation-induced brain injury. PLoS One, Vol. 7. 10.1371/journal.pone.0036529.
    CrossRef  |  
  13. Rong, X., Y. Tang, M. Chen, K. Lu and Y. Peng, 2012. Radiation-induced cranial neuropathy in patients with nasopharyngeal carcinoma. Strahlenther. Onkol., 188: 282-286.
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  14. Gong, H.X., L. He, X.P. Li, Y.D. Wang and Y. Li et al., 2012. Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirus. Oncol. Rep., 27: 1163-1169.
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  15. Tang, Y., Y. Li, D. Luo, X. Rong, J. Ye and Y. Peng, 2011. Epilepsy related to radiotherapy in patients with nasopharyngeal carcinoma. Epilepsy Res., 96: 24-28.
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  16. Tang, Y., X. Li, Y. Li, Q. Shen, X. Rong, R. Huang and Y. Peng, 2011. Renovascular hypertension causes cerebral vascular remodeling. Neural Regeneration Res., 6: 1977-1981.
  17. Tang, Y., Q. Shen, Y. Wang, K. Lu, Y. Wang and Y. Peng, 2011. A randomized prospective study of rehabilitation therapy in the treatment of radiation-induced dysphagia and trismus. Strahlenther. Onkol., 187: 39-44.
    CrossRef  |  
  18. Lu, J., M.L. He, L. Wang, Y. Chen and X. Liu et al., 2011. MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res., 71: 225-233.
    CrossRef  |  Direct Link  |  
  19. Wang, Y.D., X.P. Li, M. Li, S. Liu, X.P. Lu, Y. Peng and R.X. Huang, 2010. Relationship between cerebral hypoxic tissue volume and prognosis after stroke. Eur. Neurol., 63: 52-59.
    CrossRef  |  
  20. Tang, Y., D. Luo, W. Peng, F. Huang and Y. Peng, 2010. Ocular ischemic syndrome secondary to carotid artery occlusion as a late complication of radiotherapy of nasopharyngeal carcinoma. J. Neuro-Ophthalmol., 30: 315-320.
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  21. Peng, K., Y. Li, L. Long, D. Li and Q. Jia et al., 2010. Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish. Neurosci. Lett., 484: 98-103.
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  22. Pan, J.R., Y. Li, Z. Pei, X.P. Li, Y. Peng and Y.D. Wang, 2010. Hypoxic tissues are associated with microvessel density following brain ischemia-reperfusion. Neurol. Sci., 31: 765-771.
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  23. Lum, C.T., X. Liu, R.W. Sun, X.P. Li and Y. Peng et al., 2010. Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro. Cancer Lett., 294: 159-166.
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  24. Long, L., Y. Li, Y.D. Wang, Q.Y. He and M. Li et al., 2010. The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model. Alcoholism: Clin. Exp. Res., 34: 1929-1936.
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  25. Li, Y., H. Li, Y. Zhang, X. Sun and G. Hanley et al., 2010. Toll-like receptor 2 is required for opioids-induced neuronal apoptosis. Biochem. Biophys. Res. Commun., 391: 426-430.
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  26. Li, M., L. Wang, Y. Peng, J.C. Wang and L.H. Zhou, 2010. Knockdown of the neuronal nitric oxide synthase gene retard the development of the cerebellar granule neurons in vitro. Dev. Dyn., 239: 474-481.
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  27. Li, G., Z. Wu, Y. Peng, X. Liu and J. Lu et al., 2010. MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells. Cancer Lett., 299: 29-36.
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  28. Li, D., K. Peng, Y. Li and Y. Peng, 2010. Advancements on the zebrafish glioma model. Chinese J. Cancer, 29: 621-625.
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  29. Zhang, B., Y.X. Bai, H.H. Ma, F. Feng and R. Jin et al., 2009. Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells. Cancer Res., 69: 75-83.
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  30. Yang, L., R. Lu, L. Jiang, Z. Liu and Y. Peng, 2009. Expression and genetic analysis of tumor necrosis factor-alpha (TNF-α) G-308A polymorphism in sporadic Alzheimer's disease in a Southern China population. Brain Res., 1247: 178-181.
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  31. Xia, S., C. Duan, Q. Shen, Y. Xing, Y. Peng, E. Tao and J. Liu, 2009. Neuron-specific enolase expression in a rat model of radiation-induced brain injury following vascular endothelial growth factor-modified neural stem cell transplantation. Neural Regen. Res., 4: 739-743.
    CrossRef  |  
  32. Wang, Y., J. Pan, Y. Qiu, X. Li, M. Li and Y. Peng, 2009. Long-term existence of cerebral hypoxic tissue in a rat model of cereral ischemia/reperfusion injury. Neural Regen. Res., 4: 371-376.
  33. Liang, B., M.L. He, C.Y. Chan, Y.C. Chen and X.P. Li et al., 2009. The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat. Biomaterials, 30: 4014-4020.
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  34. Li, Z., M.L. He, H. Yao, Q.M. Dong and Y.C. Chen et al., 2009. Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules. BMB Rep., 42: 59-64.
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  35. Li, Y., X. Sun, Y. Zhang, J. Huang and G. Hanley et al., 2009. Morphine promotes apoptosis via TLR2 and this is negatively regulated by beta-arrestin 2. Biochem. Biophys. Res. Commun., 378: 857-861.
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  36. Yang, P.H., W.K. Cheung, Y. Peng, M.L. He and G.Q. Wu et al., 2008. Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal. J. Biol. Chem., 283: 8486-8495.
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  37. Tang, Y., Y. Zhang, L. Guo, Y. Peng, Q. Luo and Y. Xing, 2008. Relationship between individual radiosensitivity and radiation encephalopathy of nasopharyngeal carcinoma after radiotherapy. Strahlenther. Onkol., 184: 510-514.
    CrossRef  |  
  38. Lu, R., Q. Shen, L. Yang, M. Li, Y. Wang and Y. Peng, 2008. Effects of Kallikrein gene transfer on penumbral microvascular proliferation and regional cerebral blood flow following cerebral ischemia/reperfusion injury. Neural Regen. Res., 3: 1045-1050.
  39. Lu, R., L. Yang, Q. Shen, M. Li, X. Li and Y. Peng, 2008. Stereotaxic microinjection of adenovirus-mediated human tissue Kallikrein gene reduces apoptosis in a rat model of middle cerebral artery occlusion. Neural Regen. Res., 3: 847-852.
  40. Liang, B., M.L. He, Z.P. Xiao, Y. Li and C.Y. Chan et al., 2008. Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery. Biochem. Biophys. Res. Commun., 367: 874-880.
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  41. Li, Z., H. Yao, Y. Ma, Q. Dong and Y. Chen et al., 2008. Inhibition of HBV gene expression and replication by stably expressed interferon-α 1 via adeno-associated viral vectors. J. Gene Med., 10: 619-627.
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  42. Wang, J., Y. Yang, H.H. Xia, Q. Gu and M.C. Lin et al., 2007. Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology, 132: 1066-1076.
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  43. Ng, S.S., Y.T. Cheung, X.M. An, Y.C. Chen and M. Li et al., 2007. Cell cycle-related kinase: A novel candidate oncogene in human glioblastoma. J. Natl. Cancer Inst., 99: 936-948.
    Direct Link  |  
  44. Wang, J., Y. Peng, Y.W. Sun, H. He and S. Zhu et al., 2006. All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer. Gastroenterology, 130: 747-758.
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  45. Peng, Y., P.H. Yang, J.A. Tanner, J.D. Huang and M. Li et al., 2006. Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis. Biochem. Biophys. Res. Commun., 344: 416-426.
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  46. Luo, C., Y. Peng, R. Santti, M.L. He and M.C. Lin, 2006. COX-1 and -2 expressions in vas deferens and prostate of neonatally estrogen treated aging rats and Hydroxymatairesinol for COX-2 inhibition assay. Endocrine, 29: 161-168.
  47. Li, X.P., C.Y. Li, X. Li, Y. Ding, L.L. Chan and P.H. Yang et al., 2006. Inhibition of human nasopharyngeal carcinoma growth and metastasis in mice by adenovirus-associated virus-mediated expression of human endostatin. Mol. Cancer Ther., 5: 1290-1298.
    Direct Link  |  
  48. Li, X., X. Liu, C.Y. Li, Y. Ding and D. Chau et al., 2006. Recombinant adeno-associated virus mediated RNA interference inhibits metastasis of nasopharyngeal cancer cells in vivo and in vitro by suppression of Epstein-Barr virus encoded LMP-1. Int. J. Oncol., 29: 595-603.
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  49. Li, M., S.S. Ng, J. Wang, L. Lai and S.Y. Leung et al., 2006. EFA6A enhances glioma cell invasion through ADP ribosylation factor 6/extracellular signal-regulated kinase signaling. Cancer Res., 66: 1583-1590.
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  50. He, M.L., B.J. Zheng, Y. Chen, K.L. Wong and J.D. Huang et al., 2006. Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus. FEBS Lett., 580: 2414-2420.
    CrossRef  |  
  51. Qian, W.P., Y.Q. Tan, Y. Chen, Y. Peng and Z. Li et al., 2005. Rapid quantification of semen hepatitis B virus DNA by real-time polymerase chain reaction. World J. Gastroenterol., 11: 5385-5389.
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  52. Peng, Y., K.H. Kwok, P.H. Yang, S.S. Ng and J. Liu et al., 2005. Ascorbic acid inhibits ROS production, NF-ΚB activation and prevents ethanol-induced growth retardation and microencephaly. Neuropharmacology, 48: 426-434.
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  53. Zheng, B., M.L. He, K.L. Wong, C.T. Lum and L.L. Poon et al., 2004. Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-α/β) but not by type II interferon (IFN-γ). J. Interferon Cytokine Res., 24: 388-390.
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  54. Peng, Y., P.H. Yang, Y. Guo, S.S. Ng and J. Liu et al., 2004. Catalase and peroxiredoxin 5 protect xenopus embryos against alcohol-induced ocular anomalies. Invest. Ophthalmol. Visual Sci., 45: 23-29.
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  55. Peng, Y., P.H. Yang, S.S. Ng, O.G. Wong and J. Liu et al., 2004. A critical role of Pax6 in alcohol-induced fetal microcephaly. Neurobiol. Dis., 16: 370-376.
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  56. Peng, Y., P.H. Yang, S.S. Ng, C.T. Lum and H.F. Kung et al., 2004. Protection of Xenopus laevis embryos against alcohol-induced delayed gut maturation and growth retardation by peroxiredoxin 5 and catalase. J. Mol. Biol., 340: 819-827.
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  57. Peng, Y., B.H. Jiang, P.H. Yang, Z. Cao and X. Shi et al., 2004. Phosphatidylinositol 3-kinase signaling is involved in neurogenesis during Xenopus embryonic development. J. Biol. Chem., 279: 28509-28514.
    Direct Link  |  
  58. Li, X.P., G. Li, Y. Peng, H.F. Kung and M.C. Lin, 2004. Suppression of Epstein-Barr virus-encoded latent membrane protein-1 by RNA interference inhibits the metastatic potential of nasopharyngeal carcinoma cells. Biochem. Biophys. Res. Commun., 315: 212-218.
    CrossRef  |  
  59. He, M.L., B. Zheng, Y. Peng, J.S. Peiris and L.L. Poon et al., 2003. Inhibition of SARS-associated coronavirus infection and replication by RNA interference. JAMA, 26: 2665-2666.
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  60. Deng, Y., L. Yao, L. Chau, S.S. Ng and Y. Peng et al., 2003. N-myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int. J. Cancer, 106: 342-347.
    CrossRef  |  Direct Link  |  
  61. Wong, K., Y. Peng, H.F. Kung and M.L. He, 2002. Retina dorsal/ventral patterning by Xenopus TBx3. Biochem. Biophys. Res. Commun., 290: 737-742.
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  62. Peng, Y., R.H. Xu, J.M. Mei, X.P. Li, D. Yan, H.F. Kung and J.M. Phang, 2002. Neural inhibition by c-Jun as a synergizing factor in bone morphogenetic protein 4 signaling. Neuroscience, 109: 657-664.
    CrossRef  |  
  63. He, M.L., Y. Chen, Y. Peng, D. Jin and D. Du et al., 2002. Induction of apoptosis and inhibition of cell growth by developmental regulator hTBX5. Biochem. Biophys. Res. Commun., 297: 185-192.
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  64. Xu, R.H., Y. Peng, J. Fan, D. Yan and S. Yamagoe et al., 2000. Histone acetylation is a checkpoint in FGF-stimulated mesoderm induction. Dev. Dyn., 218: 628-635.
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  65. Peng, Y., K.H. Kok, R.H. Xu, K.H. Kwok and D. Tay et al., 2000. Maternal cold inducible RNA binding protein is required for embryonic kidney formation in Xenopus laevis. FEBS Lett., 482: 37-43.
    CrossRef  |  
  66. Liu, W., C. Ren, J. Shi, X. Feng and Z. He et al., 2000. Characterization of the functionally related sites in the neural inducing gene noggin. Biochem. Biophys. Res. Commun., 270: 293-297.
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  67. Xu, R.H., K.T. Ault, J. Kim, M.J. Park and Y.S. Hwang et al., 1999. Opposite effects of FGF and BMP-4 on embryonic blood formation: Roles of PV.1 and GATA-2. Dev. Biol., 208: 352-361.
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