Dr. Jun-Ling Shi
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Dr. Jun-Ling Shi

Professor
Northwestern Polytechnical University, China

Highest Degree
Ph.D. in Biotechnology from Northwest A&F University, China

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Area of Interest:

Biomedical Sciences
100%
Microbial Biotechnology
62%
Fermentation
90%
Enzyme Engineering
75%
Biotechnology
55%

Research Publications in Numbers

Books
0
Chapters
2
Articles
149
Abstracts
0

Selected Publications

  1. Zhao, X., Y. Zhang, J. Shi, Y. Liu, Y. Lu and Z. Lian, 2019. Biosynthesis of antibacterial compound against multidrug resistant foodborne pathogens by Phomopsis sp. XP-8. Food Control, 95: 223-231.
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  2. Zhao, X., L. Yan, X. Xu, H. Zhao and Y. Lu et al., 2019. Synthesis of silver nanoparticles and its contribution to the capability of Bacillus subtilis to deal with polluted waters. Applied Microbiol. Biotechnol., 103: 6319-6332.
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  3. Zhao, X., H. Zhao, L. Yan, N. Li, J. Shi and C. Jiang, 2019. Recent developments in detection using noble metal nanoparticles. Crit. Rev. Anal. Chem., (In Press). 10.1080/10408347.2019.1576496.
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  4. Zhao, H., X. Zhao, S. Lei, Y. Zhang and D. Shao et al., 2019. Effect of cell culture models on the evaluation of anticancer activity and mechanism analysis of the potential bioactive compound, iturin A, produced by Bacillus subtilis. Food Funct., 10: 1478-1489.
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  5. Zhao, H., X. Xu, S. Lei, D. Shao and C. Jiang et al., 2019. Iturin A-like lipopeptides from Bacillus subtilis trigger apoptosis, paraptosis and autophagy in Caco-2 cells. J. Cell. Physiol., 234: 6414-6427.
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  6. Yan, L., J. Zhu, X. Zhao, J. Shi, C. Jiang and D. Shao, 2019. Beneficial effects of endophytic fungi colonization on plants. Applied Microbiol. Biotechnol., 103: 3327-3340.
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  7. Xu, X., Y. Yang, X. Zhao, H. Zhao and Y. Lu et al., 2019. Recovery of gold from electronic wastewater by Phomopsis sp. XP-8 and its potential application in the degradation of toxic dyes. Bioresour. Technol., Vol. 288. 10.1016/j.biortech.2019.121610.
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  8. Rajoka, M.S.R., H. Zhao, H.M. Mehwish, N. Li and Y. Lu et al., 2019. Anti-tumor potential of cell free culture supernatant of Lactobacillus rhamnosus strains isolated from human breast milk. Food Res. Int., 123: 286-297.
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  9. Qu, R., C. Jiang, W. Wu, B. Pang and S. Lei et al., 2019. Conversion of DON to 3-epi-DON in vitro and toxicity reduction of DON in vivo by Lactobacillus rhamnosus. Food Funct., 10: 2785-2796.
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  10. Pang, B., X. Xu, Y. Lu, H. Jin and R. Yang et al., 2019. Prediction of new targets and mechanisms for quercetin in the treatment of pancreatic cancer, colon cancer and rectal cancer. Food Funct., 10: 5339-5349.
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  11. Lu, Y., C. Ye, J. Che, X. Xu and D. Shao et al., 2019. Genomic sequencing, genome-scale metabolic network reconstruction and in silico flux analysis of the grape endophytic fungus Alternaria sp. MG1. Microb. Cell Fact., Vol. 18. 10.1186/s12934-019-1063-7.
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  12. Li, J., H. Zhao, X. Hu, J. Shi, D. Shao and M. Jin, 2019. Antidiabetic effects of different polysaccharide fractions from Artemisia sphaerocephala Krasch seeds in db/db mice. Food Hydrocolloids, 91: 1-9.
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  13. Lei, S., H. Zhao, B. Pang, R. Qu and Z. Lian et al., 2019. Capability of iturin from Bacillus subtilis to inhibit Candida albicans in vitro and in vivo. Applied Microbiol. Biotechnol., 103: 4377-4392.
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  14. Jin, M., H. Zhang, J. Wang, D. Shao and H. Yang et al., 2019. Response of intestinal metabolome to polysaccharides from mycelia of Ganoderma lucidum. Int. J. Biol. Macromol., 122: 723-731.
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  15. Jiang, C., D. Guo, Z. Li, S. Lei, J. Shi and D. Shao, 2019. Clinostat rotation affects metabolite transportation and increases organic acid production by Aspergillus carbonarius, as revealed by differential metabolomic analysis. Applied Environ. Microbiol., Vol. 85, No. 18. 10.1128/AEM.01023-19.
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  16. Zhu, J., L. Yan, X. Xu, Y. Zhang, J. Shi, C. Jiang and D. Shao, 2018. Strategies to enhance the production of pinoresinol and its glucosides by endophytic fungus (Phomopsis sp. XP-8) isolated from Tu-chung bark. AMB Express, Vol. 8. 10.1186/s13568-018-0584-5.
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  17. Zhao, X., L. Zhou, M.S.R. Rajoka, L. Yan and C. Jiang et al., 2018. Fungal silver nanoparticles: Synthesis, application and challenges. Crit. Rev. Biotechnol., 38: 817-835.
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  18. Zhao, H., L. Yan, X. Xu, C. Jiang and J. Shi et al., 2018. Potential of Bacillus subtilis lipopeptides in anti-cancer I: Induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells. AMB Express, Vol. 8. 10.1186/s13568-018-0606-3.
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  19. Zhao, H., J. Li, Y. Zhang, S. Lei and X. Zhao et al., 2018. Potential of iturins as functional agents: Safe, probiotic and cytotoxic to cancer cells. Food Funct., 9: 5580-5587.
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  20. Zhang, Y., H. Zhao, Y. Di, Q. Li, D. Shao, J. Shi and Q. Huang, 2018. Antitumor activity of Pinoresinol in vitro: Inducing apoptosis and inhibiting HepG2 invasion. J. Funct. Foods, 45: 206-214.
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  21. Yan, L., H. Zhao, X. Zhao, X. Xu and Y. Di et al., 2018. Production of bioproducts by endophytic fungi: Chemical ecology, biotechnological applications, bottlenecks and solutions. Applied Microbiol. Biotechnol., 102: 6279-6298.
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  22. Shao, D., Z. Lian, Y. Di, L. Zhang and M.S.R. Rajoka et al., 2018. Dietary compounds have potential in controlling atherosclerosis by modulating macrophage cholesterol metabolism and inflammation via miRNA. NPJ Sci. Food, Vol. 2. 10.1038/s41538-018-0022-8.
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  23. Rajoka, M.S.R., M. Jin, Z. Haobin, Q. Li, D. Shao, Q. Huang and J. Shi, 2018. Impact of dietary compounds on cancer-related gut microbiota and microRNA. Applied Microbiol. Biotechnol., 102: 4291-4303.
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  24. Rajoka, M.S.R., M. Jin, Z. Haobin, Q. Li and D. Shao et al., 2018. Functional characterization and biotechnological potential of exopolysaccharide produced by Lactobacillus rhamnosus strains isolated from human breast milk. LWT-Food Sci. Technol., 89: 638-647.
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  25. Rajoka, M.S.R., H. Zhao, Y. Lu, Z. Lian and N. Li et al., 2018. Anticancer potential against cervix cancer (HeLa) cell line of probiotic Lactobacillus casei and Lactobacillus paracasei strains isolated from human breast milk. Food Funct., 9: 2705-2715.
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  26. Rajoka, M.S.R., H. Zhao, N. Li, Y. Lu and Z. Lian et al., 2018. Origination, change, and modulation of geriatric disease-related gut microbiota during life. Applied Microbiol. Biotechnol., 102: 8275-8289.
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  27. Liu, J., L. Liu, Z. Tian, Y. Li and C. Shi et al., 2018. In silico discovery of a small molecule suppressing lung carcinoma A549 cells proliferation and inducing autophagy via mTOR pathway inhibition. Mol. Pharmaceut., 15: 5427-5436.
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  28. Li, Y., X. Xu, R. Qu, G. Zhang and M.S.R. Rajoka et al., 2018. Heterologous expression of Oenococcus oeni sHSP20 confers temperature stress tolerance in Escherichia coli. Cell Stress Chaperones, 23: 653-662.
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  29. Li, Q., Q. Huang, T. Huyan, Y. Wang, Q. Huang and J. Shi, 2018. Bifacial effects of engineering tumour cell-derived exosomes on human natural killer cells. Exp. Cell Res., 363: 141-150.
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  30. Jin, M., H. Zhang, K. Zhao, C. Xu and D. Shao et al., 2018. Responses of intestinal mucosal barrier functions of rats to simulated weightlessness. Front. Physiol., Vol. 9. 10.3389/fphys.2018.00729.
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  31. Jiang, C., X. Chen, S. Lei, D. Shao, J. Zhu, Y. Liu and J. Shi, 2018. Fungal spores promote the glycerol production of Saccharomyces cerevisiae by upregulating the oxidative balance pathway. J. Agric. Food Chem., 66: 3188-3198.
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  32. Gao, Z., Z. Zhang, X. Xu, J. Che, Y. Zhang, Y. Liu and J. Shi, 2018. Genomic analysis reveals the biosynthesis pathways of diverse secondary metabolites and pinoresinol and its glycoside derivatives in Phomopsis sp. XP-8. Acta Microbiol. Sin., 58: 939-954.
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  33. Zhu, J., K. Lu, X.G. Xu, X.L. Wang and J.L. Shi, 2017. Purification and characterization of a novel glutamate dehydrogenase from Geotrichum candidum with higher alcohol and amino acid activity. AMB Express, Vol. 7. 10.1186/s13568-016-0307-8.
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  34. Zhao, H., D. Shao, C. Jiang, J. Shi and Q. Li et al., 2017. Biological activity of lipopeptides from Bacillus. Applied Microbiol. Biotechnol., 101: 5951-5960.
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  35. Shao, D., L. Yao, J. Zhu, J. Shi, M. Jin, Q. Huang and H. Yang, 2017. Simulated microgravity affects some biological characteristics of Lactobacillus acidophilus. Applied Microbiol. Biotechnol., 101: 3439-3449.
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  36. Rajoka, M.S.R., J. Shi, J. Zhu, D. Shao, Q. Huang, H. Yang and M. Jin, 2017. Capacity of lactic acid bacteria in immunity enhancement and cancer prevention. Applied Microbiol. Biotechnol., 101: 35-45.
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  37. Rajoka, M.S.R., H.M. Mehwish, M. Siddiq, Z. Haobin and J. Zhu et al., 2017. Identification, characterization and probiotic potential of Lactobacillus rhamnosus isolated from human milk. LWT-Food Sci. Technol., 84: 271-280.
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  38. Lu, Y., J. Zhu, J. Shi, Y. Liu, D. Shao and C. Jiang, 2017. Immobilized enzymes from Geotrichum spp. improve wine quality. Applied Microbiol. Biotechnol., 101: 6637-6649.
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  39. Li, J., M.S.R. Rajoka, D. Shao, C. Jiang and M. Jin et al., 2017. Strategies to increase the efficacy of using gut microbiota for the modulation of obesity. Obesity Rev., 18: 1260-1271.
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  40. Jin, M., Y. Zhu, D. Shao, K. Zhao and C. Xu et al., 2017. Effects of polysaccharide from mycelia of Ganoderma lucidum on intestinal barrier functions of rats. Int. J. Biol. Macromol., 94: 1-9.
    CrossRef  |  Direct Link  |  
  41. Jiang, C., X. Chen, S. Lei, H. Zhao, Y. Liu and J. Shi, 2017. Lipopeptides from Bacillus subtilis have potential application in the winemaking process: Inhibiting fungal and ochratoxin A contamination and enhancing esters and acids biosynthesis. Aust. J. Grape Wine Res., 23: 350-358.
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  42. Zhu, J., J.L. Shi, Y. Lu, L.P. Liu and Y.L. Liu, 2016. Application of strains of geotrichum spp. To decrease higher alcohols and to increase ester. J. Inst. Brewing, 122: 147-155.
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  43. Zhang, Y., J.L. Shi, Z.H. Gao, J.X. Che, D.Y. Shao and Y.L. Liu, 2016. Comparison of pinoresinol diglucoside production by Phomopsis sp.XP-8 in different media and the characterisation and product profiles of the cultivation in mung bean. J. Sci. Food Agric., 96: 4015-4025.
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  44. Shao, D.Y., Y.L. Wang, Q.S. Huang, J.L. Shi and H. Yang et al., 2016. Cholesterol-lowering effects and mechanisms in view of bile acid pathway of resveratrol and resveratrol glucuronides. J. Food Sci., 81: 2841-2848.
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  45. Shao, D.Y., L.J. Zhang, S.K. Du, W. Yokoyama, J.L. Shi, N. Li and J.X. Wang, 2016. Polyphenolic content and color of seedless and seeded shade dried chinese raisins. Food Sci. Technol. Res., 22: 359-369.
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  46. Shao, D.Y., L.B. Yao, M.S.R. Rajoka, J. Zhu and J.L. Shi et al., 2016. Simulated microgravity affects some biological characteristics of Lactobacillus acidophilus. Appl. Microbiol. Biotechnol., 10.1007/s00253-016-8059-6.
    CrossRef  |  Direct Link  |  
  47. Rajoka, M.S.R., J.L. Shi, J. Zhu, D.Y. Shao, Q.S. Huang, H. Yang and M.L. Jin, 2016. Capacity of lactic acid bacteria in immunity enhancement and cancer prevention. Appl. Microbiol. Biotechnol., 10.1007/s00253-016-8005-7.
    CrossRef  |  Direct Link  |  
  48. Lu, Y., D. Shao, J. Shi, Q. Huang, H. Yang and M. Jin, 2016. Strategies for enhancing resveratrol production and the expression of pathway enzymes. Applied Microbiol. Biotechnol., 100: 7407-7421.
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  49. Chen, Z.N., J.L. Shi, X.J. Yang, Y. Liu, B. Nan and Z.F. Wang, 2016. Isolation of exopolysaccharide-producing bacteria and yeasts from Tibetan kefir and characterisation of the exopolysaccharides. Int. J. Dairy Technol., 69: 410-417.
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  50. Chen, D.F., J.L. Shi and X.Z. Hu, 2016. Enhancement of polyphenol content and antioxidant capacity of oat (Avena nuda L.) bran by cellulase treatment. Appl. Biol. Chem., 59: 397-403.
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  51. Che, J.X., J.L. Shi, Z.H. Gao and Y. Zhang, 2016. Transcriptome analysis reveals the genetic basis of the resveratrol biosynthesis pathway in an endophytic fungus (alternaria sp. MG1) isolated from vitis vinifera. Front. Microbiol., 10.3389/fmicb.2016.01257.
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  52. Che, J.X., J.L. Shi, Z.H. Gao and Y. Zhang, 2016. A new approach to produce resveratrol by enzymatic bioconversion. J. Microbiol. Biotechnol., 28: 1348-1357.
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  53. Che, J.X., J.L. Shi, Y. Lu and Y.L. Liu, 2016. Validation of reference genes for normalization of gene expression by qRT‑PCR in a resveratrol‑producing entophytic fungus (Alternaria sp. MG1). AMB Express, 10.1186/s13568-016-0283-z.
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  54. Zhu, C.Y., J.L. Shi, C.M. Jiang and Y.L. Liu, 2015. Inhibition of the growth and ochratoxin A production by Aspergillus carbonarius and Aspergillus ochraceus in vitro and in vivo through antagonistic yeasts. Food Control, 50: 125-132.
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  55. Zhang, Y., J. Shi, Z. Gao, R. Yangwu, H. Jiang, J. Che and Y. Liu, 2015. Production of pinoresinol diglucoside, pinoresinol monoglucoside and pinoresinol by Phomopsis sp. XP-8 using mung bean and its major components. Applied Microbiol. Biotechnol., 99: 4629-4643.
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  56. Zhang, Y., J. Shi, L. Liu, Z. Gao, J. Che, D. Shao and Y. Liu, 2015. Bioconversion of pinoresinol diglucoside and pinoresinol from substrates in the phenylpropanoid pathway by resting cells of Phomopsis sp.XP-8. PLoS One, 10.1371/journal.pone.0137066.
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  57. Shao, D.Y., J. Li, J. Li, R.H. Tang and L. Liu et al., 2015. Inhibition of Gallic Acid on the Growth and Biofilm Formation of Escherichia coli and Streptococcus mutans. J. Food Sci., 80: 1299-1305.
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  58. Shao, D.Y., C. Venkitasamy, X. Li, Z.L. Pan and J.L. Shi et al., 2015. Thermal and storage characteristics of tomato seed oil. LWT-Food Sci. Technol., 63: 191-197.
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  59. Jiang, C.M., J.L. Shi, X.Q. Chen and Y.L. Liu, 2015. Effect of sulfur dioxide and ethanol concentration on fungal profile and ochratoxin a production by Aspergillus carbonarius during wine making. Food Control, 47: 656-663.
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  60. Chen, Z.N., J.L. Shi, X.J. Yang, B. Nan, Y. Liu and Z.F. Wang, 2015. Chemical and physical characteristics and antioxidant activities of the exopolysaccharide produced by Tibetan kefir grains during milk fermentation. Int. Dairy J., 43: 15-21.
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  61. Chen, D.F., J.L. Shi, X.Z. Hu and S.K. Du, 2015. Alpha-amylase treatment increases extractable phenolics and antioxidant capacity of oat (Avena nuda L.) flour. J. Cereal Sci., 65: 60-66.
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  62. Zheng, Y.J., J.L. Shi, Z.L. Pan, Y.L. Cheng, Y. Zhang and N. Li, 2014. Effect of heat treatment, pH, sugar concentration, and metal ion addition on green color retention in homogenized puree of Thompson seedless grape. LWT-Food Sci. Technol., 55: 595-603.
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  63. Li, N., J.L. Shi and K. Wang, 2014. Profile and Antioxidant Activity of Phenolic Extracts from 10 Crabapples (Malus Wild Species). J. Agric. Food Chem., 62: 574-581.
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  64. Jiang, J.M., J.L. Shi, Y.L. Liu and Z.Y. Zhu, 2014. Inhibition of Aspergillus carbonarius and fungal contamination in table grapes using Bacillus subtilis. Food Control, 35: 41-48.
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  65. Jiang, C.M., J.L. Shi, Y.L. Cheng and Y.L. Liu, 2014. Effect of Aspergillus carbonarius amounts on winemaking and ochratoxin A contamination. Food Control. Food Control, 40: 85-92.
  66. Zhang, J.H., J.L. Shi, H.L. Lv and Y.L. Liu, 2013. Induction of hexanol dehydrogenase in Geotrichum spp. by the addition of hexanol. Appl. Microbiol. Biotechnol., 97: 1279-1287.
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  67. Zhang, J.H., J.L. Shi and Y.L. Liu, 2013. Bioconversion of resveratrol using resting cells of non-genetically modified Alternaria sp. Biotechnol. Appl. Biochem., 60: 236-243.
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  68. Jiang, C.M., J.L. Shi and C.Y. Zhu, 2013. Fruit spoilage and ochratoxin a production by Aspergillus carbonarius in the berries of different grape cultivars. Food Control, 30: 93-100.
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  69. Chunmei, J., S. Junling, H. Qian and L. Yanlin, 2013. Occurrence of toxin-producing fungi in intact and rotten table and wine grapes and related influencing factors. Food Control, 31: 5-13.
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  70. Zhu, J., J.L. Shi and Z.L. Pan, 2012. Purification and characterization of a hexanol-degrading enzyme extracted from apple. J. Agric. Food Chem., 60: 3246-3252.
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  71. Zheng, Y., J. Shi and Z. Pan, 2012. Biochemical characteristics and thermal inhibition kinetics of polyphenol oxidase extracted from Thompson seedless grape. Euro. Food Res. Technol., 234: 607-616.
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  72. Shi, J.L., Q. Zeng, Y.L. Liu and Z.L. Pan, 2012. Alternaria sp. MG1, a resveratrol-producing fungus: isolation, identification and optimal cultivation conditions for resveratrol production. Appl. Microbiol. Biotechnol., 95: 369-379.
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  73. Shi, J.L., C. Liu, L.P. Liu, H.S. Hao, B.W. Yang and Y.Z. Zhang, 2012. Structure identification and fermentation characteristics of pinoresinol diglucoside produced by Phomopsis sp. isolated from Eucommia ulmoides Oliv. Appl. Microbiol. Biotechnol., 93: 1475-1483.
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  74. Chen, W., X. Liu, J. Shi, Y. Zheng, S. Zhao and J. Liu, 2010. Mechanism of DNA damage induced by arecaidine: The role of Cu (II) and alkaline conditions. Food Chem., 119: 433-436.
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  75. Wang, P., J.L. Shi, Y. Zhu, B. Yang and S. Du, 2009. Optimal conditions for the growth and polysaccharide production by Hypsizigus marmoreus in submerged culture. J. Food Process. Preserv., 33: 454-472.
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  76. Shi, J., Z. Pan, T.H. McHugh and E. Hirschberg, 2009. Effect of infusion method and parameters on solid gain in blueberries. Food Bioprocess Technol., 2: 271-278.
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  77. Shi, J.L., Z.L. Pan, T.H. McHugh, D. Wood, Y. Zhu, R.J. Avena-Bustillos and E. Hirschberg, 2008. Effect of berry size and sodium hydroxide pretreatment on the drying characteristics of blueberries under infrared radiation heating. J. Food Sci., 73: 259-265.
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  78. Shi, J.L., Y. Li, Y. Zheng, Y. Zhu, X.P. Zhang, G. Du and J. Chen, 2008. Tryptophan supplementation and pH adjustment for optimizing the sporulation of Coniothyrium minitans. Biotechnol. Lett., 30: 259-262.
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  79. Shi, J., Z. Pan, T.H. McHugh, D. Wood, E. Hirschberg and D.A. Olson, 2008. Drying and quality characteristics of fresh and sugar-infused blueberries dried with infrared radiation heating. Lebensmittel Wissenschaft Technologie, 41: 1962-1972.
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  80. Shi, J.L., Y. Li, H.L. Qian, G.C. Du and J. Chen, 2004. Pre-germinated conidia of Coniothyrium minitans enhances the foliar biological control of Sclerotinia sclerotiorum. Biotechnol. Lett., 26: 1649-1652.
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