Dr. Wang  Xing
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Dr. Wang Xing

Assistant Professor
Rensselaer Polytechnic Institute, USA


Highest Degree
PostDoc Fellow in RNA Biology from Princeton University, USA

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Biography

I am a structural DNA nanotechnology expert and a nucleic acid
biochemist with years of experience in applying designer DNA
nanostructures to address challenges in biological and biomedical research fields.I have years of training as a
biochemist in the field of structural DNA nanotechnology,working
first on the molecular programming of DNA nanostructures & devices in vitro,and then on the self-assembly of these
structures in vivo.To further my vision in molecular programming from synthetic DNA to the genome level in vivo,I have conducted my postdoctoral research to gain quantifications and experience in RNA-mediated genome programming and engineering in ciliate Oxytricha trifallax.My interdisciplinary background in both
chemistry and biology allows me to appreciate the capability of
designer DNA nanostructures to address complex biological problems,
which further leads to the research interests in my own lab
at RPI.

Area of Interest:

Chemistry
100%
Nanotechnology
62%
Molecular Structure
90%
RNA Structure
75%
Genetics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Deng, Y., M. Kizer, M. Rada, J. Sage, X. Wang, D.J. Cheon and A.J. Chung., 2018. Intracellular delivery of nanomaterials via an inertial microfluidic cell hydroporator. Nano lett., 10.1021/acs.nanolett.8b00704.
    CrossRef  |  Direct Link  |  
  2. Anderson, N.T., P.H. Dinolfo and X. Wang, 2018. Synthesis and characterization of porphyrin-dna constructs for the self-assembly of modular energy transfer arrays. J. Mater. Chem. C., 6: 2452-2459.
    CrossRef  |  Direct Link  |  
  3. Halvorsen, K., M.E. Kizer, X. Wang, A.R. Chandrasekaran and M. Basanta-Sanchez, 2017. Shear dependent LC purification of an engineered DNA nanoswitch and implications for DNA origami. Anal. Chem., 89: 5673-5677.
    CrossRef  |  Direct Link  |  
  4. Chandrasekaran, A.R., N. Anderson, M. Kizer, K. Halvorsen and X. Wang, 2016. Beyond the fold: Emerging biological applications of DNA origami. Chem. Bio. Chem., 17: 1081-1089.
    Direct Link  |  
  5. Bracht, J.R., X. Wang, K. Shetty, X. Chen and G.J. Uttarotai et al., 2016. Chromosome fusions triggered by noncoding RNA. RNA Biol., 10.1080/15476286.2016.1195940.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Ohayon, Y.P., R. Sha, O. Flint, W. Liu and B. Chakraborty et al., 2015. Covalent linkage of one-dimensional DNA arrays bonded by paranemic cohesion. ACS Nano, 9: 10304-10312.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Ohayon, Y.P., R. Sha, O. Flint, A.R. Chandrasekaran and H.O. Abdallah et al., 2015. Topological linkage of DNA tiles bonded by paranemic cohesion. ACS Nano, 9: 10296-10303.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Khurana, J.S., X. Wang, X. Chen, D.H. Perlman and L.F. Landweber, 2014. Transcription-independent functions of an RNA polymerase II subunit, Rpb2, during genome rearrangement in the ciliate, Oxytricha trifallax. Genetics, 197: 839-849.
    CrossRef  |  PubMed  |  Direct Link  |  
  9. Fang, W., X. Wang, J.R. Bracht, M. Nowacki and L.F. Landweber, 2012. Piwi-interacting RNAs protect DNA against loss during Oxytricha genome rearrangement. Cell, 151: 1243-1255.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Wang, X., X. Zhang, C. Mao and N.C. Seeman, 2010. Double-stranded DNA homology produces a physical signature. Proc. Natl. Acad. Sci. U.S.A., 107: 12547-12552.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Liu, W., X. Wang, T. Wang, R. Sha and N.C. Seeman, 2008. PX DNA triangle oligomerized using a novel three-domain motif. Nano Lett., 8: 317-322.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Lin, C., S. Rinker, X. Wang, Y. Liu, N.C. Seeman and H. Yan, 2008. In vivo cloning of artificial DNA nanostructures. Proc. Natl. Acad. Sci. U.S.A., 105: 17626-17631.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Wang, X. and N.C. Seeman, 2007. Assembly and characterization of 8-arm and 12-arm DNA branched junctions. J. Am. Chem. Soc., 129: 8169-8176.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Lin, C., X. Wang, Y. Liu, N.C. Seeman and H. Yan, 2007. Rolling circle enzymatic replication of a complex multi-crossover DNA nanostructure. J. Am. Chem. Soc., 129: 14475-14481.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Constantinou, P.E., T. Wang, J. Kopatsch, L.B. Israel and X. Zhang et al., 2006. Double cohesion in structural DNA nanotechnology. Org. Biomol. Chem., 4: 3414-3419.
    CrossRef  |  PubMed  |  Direct Link  |