Dr. Chang Gu Hyun
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Dr. Chang Gu Hyun

Laboratory Director/Head
Jeju National University, South Korea

Highest Degree
Ph.D. in Pathway Engineering from Myongji University, Korea

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Area of Interest:

Molecular Sciences
100%
Molecular Biology
62%
Microbiology
90%
Biochemistry
75%
Plant Biotechnology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
32
Abstracts
0

Selected Publications

  1. Yoon, W.J., Y.M. Ham, K.N. Kim, S.Y. Park, N.H. Lee, C.G. Hyun and W.J. Lee, 2009. Anti-inflammatory activity of brown alga dictyota dichotoma in murine macrophage RAW 264.7 cells. J. Med. Plant Res., 3: 1-8.
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  2. Yoon, W.J., Y.M. Ham, B.S. Yoo, J.Y. Moon, J. Koh and C.G. Hyun, 2009. Oenothera laciniata inhibits lipopolysaccharide induced production of nitric oxide, prostaglandin E2 and proinflammatory cytokines in RAW264.7 macrophages. J. Biosci. Bioeng., 107: 429-438.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Yoon, W.J., S.S. Kim, T.H. Oh, N.H. Lee and C.G. Hyun, 2009. Torreya nucifera essential oil inhibits skin pathogen growth and lipopolysaccharide-induced inflammatory effects. Int. J. Pharmacol., 5: 37-43.
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  4. Yoon, W.J., S.S. Kim, T.H. Oh, N.H. Lee and C.G. Hyun, 2009. Cryptomeria japonica essential oil inhibits the growth of drug-resistant skin pathogens and LPS-induced nitric oxide and pro-inflammatory cytokine production. Pol. J. Microbiol., 58: 61-68.
    PubMed  |  Direct Link  |  
  5. Oh, T.H., S.S. Kim, W.J. Yoon, J.Y. Kim, E.J. Yang, N.H. Lee and C.G. Hyun, 2009. Chemical composition and biological activities of Jeju Thymus quinquecostatus essential oils against Propionibacterium species inducing acne. J. Gen. Applied Microbiol., 55: 63-68.
    PubMed  |  Direct Link  |  
  6. Kim, S.S., J.Y. Kim, N.H. Lee and C.G. Hyun, 2008. Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria. J. Gen. Applied. Microbiol., 54: 101-106.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Kim, S.S., J.S. Baik, T.H. Oh, W.J. Yoon, N.H. Lee and C.G. Hyun, 2008. Biological activities of Korean Citrus obovoides and Citrus natsudaidai essential oils against acne-inducing bacteria. Biosci. Biotechnol. Biochem., 72: 2507-2513.
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  8. Kim, S.S., J.A. Lee, J.Y. Kim, N.H. Lee and C.G. Hyun, 2008. Citrus peel wastes as functional materials for cosmeceuticals. J. Appl. Biol. Chem., 51: 7-12.
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  9. Kim, S.S., H.J. Oh, J.S. Baik, P.Y. Yun, C.S. Kim, N.H. Lee and C.G. Hyun, 2008. Chemical composition and biological activities of elsholtzia splendens essential oil. J. Appl. Biol. Chem., 51: 69-72.
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  10. Kim, J.Y., T.H. Oh, B.J. Kim, S.S. Kim, N.H. Lee and C.G. Hyun, 2008. Chemical composition and anti-inflammatory effects of essential oil from Farfugium japonicum flower. J. Oleo Sci., 57: 623-628.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Baik, J.S., S.S. Kim, J.A. Lee, T.H. Oh, J.Y. Kim, N.H. Lee and C.G. Hyun, 2008. Chemical composition and biological activities of essential oils extracted from Korean endemic citrus species. J. Microbiol. Biotechnol., 18: 74-79.
    PubMed  |  
  12. Lee, J., E. Jung, J. Lee, S. Huh, Y.C. Boo, C.G. Hyun, Y.S. Kim and D. Park, 2007. Mechanisms of melanogenesis inhibition by 2,5-dimethyl-4-hydroxy-3(2H)-furanone (DMHF). Bt. J. Dermatol., 157: 242-248.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Lee, D.W., C.G. Hyun and S.D. Lee, 2007. Nocardioides marinisabuli sp. nov., a novel actinobacterium isolated from beach sand. Int. J. Syst. Evol. Microbiol., 57: 2960-2963.
    PubMed  |  Direct Link  |  
  14. Kim, S.Y., J.S. Park, J. Shin, C.G. Hyun, J.Y. Lee and K.B. Oh, 2007. Genetic organization of the biosynthetic gene cluster for the indolocarbazole K-252a in nonomuraea longicatena JCM 11136. Applied Microbiol. Biotechnol., 75: 1119-1126.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Lee, J., E. Jung, C.G. Hyun, J. Lee and S. Hur et al., 2006. Herbal Extracts as a NF-kappaB Inhibitor. J. 32: 135-140.
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  16. Hyun, C.G., S.S. Kim and J.W. Suh, 2006. Identification of essential amino acid residues in valine dehydrogenase from Streptomyces albus. J. Microbiol., 44: 50-53.
    PubMed  |  
  17. Hyun, C.G., S.Y. Kim, J.H. Hur, M.J. Seo, J.W. Suh and S.O. Kim, 2005. Molecular detection of alpha-glucosidase inhibitor-producing actinomycetes. J. Microbiol., 43: 313-318.
    PubMed  |  
  18. Bililign, T., C.G. Hyun, J.S. Williams, A.M. Czisny and J.S. Thorson, 2004. The hedamycin locus implicates a novel aromatic PKS priming mechanism. Chem. Biol., 11: 959-969.
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  19. Jung, Y.G., S.H. Kang, C.G. Hyun, Y.Y. Yang, C.M. Kang and J.W. Suh, 2003. Isolation and characterization of bluensomycin biosynthetic genes from Streptomyces bluensis. FEMS. Microbiol. Lett., 219: 285-289.
    CrossRef  |  PubMed  |  Direct Link  |  
  20. Kim, J.M., Y. Jin, C.G. Hyun, J.H. Kim and H.S. Lee et al., 2002. Molecular cloning and analysis of the gene for P-450 hydroxylase from Pseudonocardia autotrophica IFO 12743. J. Microbiol., 40: 211-218.
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  21. Her, J.H., Y.H. Choeng, J.H. Kim, S.K. Sin and C.G. Hyun et al., 2002. Identification of a protein kinase using a FITC-labelled synthetic peptide in Streptomyces griseus IFO 13350. Kor. J. Microbiol. Biotechnol., 30: 235-240.
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  22. Kim, S.S., J.H. Bang, C.G. Hyun, J.W. Kim, J.J. Han and J.W. Suh, 2000. A new deoxyhexose biosynthetic gene cluster in Streptomyces griseus atcc10137: heterologous expression of dtdp-d-glucose 4,6-dehydratase gene. Agric. Chem. Biotechnol., 43: 136-140.
  23. Hyun, C.G., S.S. Kim, K.H. Park and J.W. Suh, 2000. Valine dehydrogenase from Streptomyces albus: Gene cloning, heterologous expression and identification of active site by site-directed mutagenesis. FEMS. Microbiol. Lett., 182: 29-34.
    CrossRef  |  PubMed  |  Direct Link  |  
  24. Hyun, C.G., S.S. Kim, J.K. Sohng, J.J. Hahn, J.W. Kim and J.W. Suh, 2000. An efficient approach for cloning the dNDP-glucose synthase gene from actinomycetes and its application in Streptomyces spectabilis, a spectinomycin producer. FEMS. Microbiol. Lett., 183: 183-189.
    CrossRef  |  PubMed  |  Direct Link  |  
  25. Hyun, C.G. and J.W. Suh, 1999. Development of PCR-Based screening methods for macrolide type polyketides in actinomycetes. Agric. Chem. Biotechnol., 42: 119-124.
  26. Kim, S.O., C.G. Hyun and J.W. Suh, 1998. Efficient cloning of the genes for RNA polymerase sigma-like factors from Actinomycetes. J. Microbiol. Biotechnol., 8: 280-283.
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  27. Kim, J.M., S.Y. Kim, C.G. Hyun, J.W. Suh and S.K. Hong, 1998. Cloning strategies of the genes for P-450 type vitamine D3 hydroxylase from actinomycetes. J. Nat. Sci. (Myong Ji Univ.), 17: 137-145.
  28. Hyun, C.G., J.W. Kim, J.J. Han, Y.N. Choi and J.W. Suh, 1998. Cloning and sequence analysis of the Aminoglycoside resistance gene from a nebramycin complex producer, Streptoalloteichus hindustanus. J. Microbiol. Biotechnol., 8: 146-151.
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  29. Hyun, C.G., J.M. Kim, S.K. Hing and J.W. Suh, 1998. An efficient approach for cloning P450 hydroxylase genes from Actinomycetes. J. Microbiol. Biotechnol., 8: 295-299.
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  30. Hyun, C.G., K.H. Park, J.W. Suh and C.R. Hutchinson, 1997. Nucleotide sequence analysis of a second set of the polyketide synthase beta-ketoacyl synthase and chain length factor genes from the salinomycin-producing streptomyces albus. J. Microbiol., 35: 40-46.
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  31. Kim, S.S., C.G. Hyun, J.W. Suh, Y.M. Kim and J.H. Lee et al., 1995. Molecular cloning and sequence analysis of the gene for secy from Streptomyces coelicolor (Muller). Korean J. Applied Microbiol. Biotechnol., 23: 678-686.
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  32. Kim, J.W., J.J. Han, Y.N. Choi, J.H. Eom, S.J. Yoon, C.G. Hyun and J.W. Suh, 1995. Cloning and sequencing of resistance determinants to aminoglycoside antibiotics from Streptoalloteichus hindustanus ATCC 31219. Kor. J. Appl. Microbiol. Biotechnol., 23: 384-389.
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