Dr. Heni Rachmawati
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Dr. Heni Rachmawati

Associate Professor
Pharmaceutics School of Pharmacy, Bandung Institute of Technology, Bandung, West Java, Indonesia


Highest Degree
Ph.D. in Pharmacy from National University of Singapore, Singapore

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Area of Interest:

Pharmacology and Toxicology
100%
Drug Delivery System
62%
Nanotechnology-Based Formulation
90%
Solid Formulation
75%
Solid Processing
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
79
Abstracts
2

Selected Publications

  1. Saraswaty, V., I.K. Adnyana, S. Pudjiraharti, T. Mozef, M. Insanu, N.F. Kurniati and H. Rachmawati, 2017. Fractionation using adsorptive macroporous resin HPD-600 enhances antioxidant activity of Gnetum gnemon L. seed hard shell extract. J. Food Sci. Technol., 54: 3349-3357.
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  2. Rachmawati, H., M.A. Novel, S. Ayu, G. Berlian, O.M. Tandrasasmita, R.R. Tjandrawinata and K. Anggadiredja, 2017. The in vitro-in vivo safety confirmation of PEG-40 hydrogenated castor oil as a surfactant for oral nanoemulsion formulation. Sci. Pharm., 85: 18-27.
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  3. Rachmawati, H., M.A. Novel, R.M. Nisa, G. Berlian and O.M. Tandrasasmita et al., 2017. Co-delivery of curcumin-loaded nanoemulsion and Phaleria macrocarpa extract to NIH 3T3 cell for antifibrosis. J. Drug Deliv. Sci. Technol., 39: 123-130.
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  4. Rachmawati, H., A.T. Pradana, D. Safitri and I.K. Adnyana, 2017. Multiple functions of D-α-Tocopherol Polyethylene Glycol 1000 Succinate (TPGS) as curcumin nanoparticle stabilizer: In vivo kinetic profile and anti-ulcerative colitis analysis in animal model. Pharmaceutics, Vol. 9. 10.3390/pharmaceutics9030024.
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  5. Ismaya, W.T., O.M. Tandrasasmita, S. Sundari, X. Lai and D.S. Retnoningrum et al., 2017. The light subunit of mushroom Agaricus bisporus tyrosinase: Its biological characteristics and implications. Int. J. Biol. Macromol., 102: 308-314.
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  6. Ismaya, W.T., A. Efthyani, R.R. Tjandrawinata and H. Rachmawati, 2017. Biological responses in Balb/c mice after long-term parenteral administration of the light subunit of mushroom tyrosinase. J. Biochem. Mol. Toxicol., Vol. 31. 10.1002/jbt.21958.
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  7. Ismaya, W.T., A. Efthyani, D.S. Retnoningrum, X. Lai, B.W. Dijkstra, R.R. Tjandrawinata and H. Rachmawati, 2017. Study of response of Swiss Webster mice to light subunit of mushroom tyrosinase. Biotech. Histochem., 92: 411-416.
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  8. Rahma, A., M.M. Munir, A. Prasetyo, V. Suendo and H. Rachmawati, 2016. Intermolecular interactions and the release pattern of electrospun curcumin-polyvinyl (pyrrolidone) fiber. Biol. Pharm. Bull., 39: 163-173.
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  9. Rachmawati, H., Y.L. Yanda, A. Rahma and N. Mase, 2016. Curcumin-loaded PLA nanoparticles: Formulation and physical evaluation. Sci. Pharm., 84: 191-202.
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  10. Rachmawati, H., I.S. Soraya, N.F. Kurniati and A. Rahma, 2016. In vitro study on antihypertensive and antihypercholesterolemic effects of a curcumin nanoemulsion. Sci. Pharm., 84: 131-140.
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  11. Rachmawati, H., E. Sulastri, M.I. Iwo, D. Safitri and A. Rahma, 2016. Bromelain encapsulated in self assembly nanoemulsion exhibits better debridement effect in animal model of burned skin. J. Nano Res., 40: 158-166.
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  12. Rachmawati, H., D. Safitri, A.T. Pradana and I.K. Adnyana, 2016. TPGS-stabilized curcumin nanoparticles exhibit superior effect on carrageenan-induced inflammation in wistar rat. Pharmaceutics, Vol. 8. 10.3390/pharmaceutics8030024.
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  13. Rachmawati, H., A. Rahma, L. Al Shaal, R.H. Muller and C.M. Keck, 2016. Destabilization mechanism of ionic surfactant on curcumin nanocrystal against electrolytes. Sci. Pharm., 84: 685-693.
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  14. Rachmawati, H., A. Jessica, Y.C. Sumirtaputra, D.S. Retnoningrum, A. Adlia and R.A. Ningrum, 2016. Removing a cystein group on interferon alpha 2b at position 2 and 99 does not diminish antitumor activity of the protein, even better. Sci. Pharm., 84: 113-130.
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  15. Ismaya, W.T., S. Damayanti, C. Wijaya, R.R. Tjandrawinata, D.S. Retnoningrum and H. Rachmawati, 2016. In silico study to develop a lectin-like protein from mushroom Agaricus bisporus for pharmaceutical application. Sci. Pharm., 84: 203-217.
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  16. Ismaya, W.T., A. Efthyani, X. Lai, D.S. Retnoningrum, H. Rachmawati, B.W. Dijkstra and R.R. Tjandrawinata, 2016. A novel immune-tolerable and permeable lectin-like protein from mushroom Agaricus bisporus. Biochem. Biophys. Res. Commun., 473: 1090-1093.
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  17. Risdian, C., M. Nasir, A. Rahma and H. Rachmawati, 2015. The influence of formula and process on physical properties and the release profile of PVA/BSA nanofibers formed by electrospinning technique. J. Nano Res., 31: 103-116.
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  18. Rahma, A., M.M. Munir and H. Rachmawati, 2015. The influence of non-ionic surfactant on the physical characteristics of curcumin-loaded nanofiber manufactured by electrospinning method. Adv. Mater. Res., 1112: 429-432.
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  19. Rachmawati, H., D.K. Budiputra and R. Mauludin, 2015. Curcumin nanoemulsion for transdermal application: Formulation and evaluation. Drug Dev. Ind. Pharm., 41: 560-566.
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  20. Rachmawati, H., B.M. Haryadi, K. Anggadiredja and V. Suendo, 2015. Intraoral film containing insulin-phospholipid microemulsion: Formulation and in vivo hypoglycemic activity study. AAPS PharmSciTech., 16: 692-703.
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  21. Maryana, W., A. Rahma, D. Mudhakir and H. Rachmawati, 2015. Phytosome containing silymarin for oral administration: Formulation and physical evaluation. J. Biomimetics Biomater. Biomed. Eng., 25: 54-65.
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  22. Christy, G., R.R. Tjandrawinata and H. Rachmawati, 2015. Tabletting process of pellets containing bioactive fraction DLBS1033F isolated from Lumbricus rubellus: Challenge and strategy. Biol. Pharm. Bull., 38: 1843-1849.
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  23. Tjandrawinata, R.R., J. Trisina, P. Rahayu, L.A. Prasetya, A. Hanafiah and H. Rachmawati, 2014. Bioactive protein fraction DLBS1033 containing lumbrokinase isolated from Lumbricus rubellus: Ex vivo, in vivo and pharmaceutic studies. Drug Des. Dev. Ther., 8: 1585-1593.
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  24. Rachmawati, H., L. Meylina, A. Rahma and Y.C. Sumirtapura, 2014. Size-dependent of oil droplet of curcumin nanoemulsion on the in vivo release kinetic of curcumin after oral and intravenous administrations in animal model. Adv. Sci. Eng. Med., 6: 959-964.
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  25. Rachmawati, H., I.K. Adnyana and K. Anggadiredja, 2014. The dual positive actions of colonic release of ibuprofen in TNBS-induced colitis wistar rats. J. Biomed. Sci. Eng., 7: 573-583.
  26. Rachmawati, H., F. Damanhuri, I.A. Darfiansyah and D. Retnoningrum, 2014. Pegylation of recombinant mutein strep to kinase from overproduction in Eschericia coli BL21 and study on the fibrinolytic activity in vitro. Int. J. Pharm. Pharm. Sci., 6: 137-141.
  27. Rachmawati, H., C.W. Yee and A. Rahma, 2014. Formulation of tablet containing curcumin nanoemulsion. Int. J. Pharm. Pharm. Sci., 6: 115-120.
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  28. Rachmawati, H. and B.M. Haryadi, 2014. The influence of polymer structure on the physical characteristic of intraoral film containing BSA-loaded nanoemulsion. J. Nanomed. Nanotechnol., 5: 1-6.
  29. Mudhakir, D., C. Wibisono and H. Rachmawati, 2014. Encapsulation of risperidone into chitosan-based nanocarrier via ionic binding interaction. Proc. Chem., 13: 92-100.
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  30. Chrysti, G. and H. Rachmawati, 2014. Development of a buoyancy-based multiple-unit gastro retentive system containing metformin hydrochloride to improve antidiabetic activity. Int. J. Innov. Drug Discov., 4: 107-114.
  31. Rachmawati, H., L. Al Shaal, R.H. Muller and C.M. Keck, 2013. Development of curcumin nanocrystal: Physical aspects. J. Pharm. Sci., 102: 204-214.
  32. Rachmawati, H., K. Apparavoo, Anatasia and K. Anggadiredja, 2013. Study the potency of colonic pellet containing ibuprofen on the suppression of gastroduodenal ulceration in male Wistar rats. Int. J. Res. Pharm. Sci., 4: 523-527.
  33. Rachmawati, H., C.A. Edityaningrum and R. Mauludin, 2013. Molecular inclusion complex of curcumin-β-cyclodextrin nanoparticle to enhance curcumin skin permeability from hydrophilic matrix gel. AAPS PharmSciTech, 14: 1303-1312.
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  34. Rachmawati, H., A. Merika, R.A. Ningrum, K. Anggadiredja and D.S. Retnoningrum, 2013. Evaluation of adverse effects of mutein forms of recombinant human interferon alpha-2b in female Swiss webster mice. BioMed Res. Int., Vol. 2013. 10.1155/2013/943687.
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  35. Rachmawati, H., 2013. Curcumin nanoforms promise better therapeutic values. Int. J. Res. Pharm. Sci., 4: 211-220.
  36. Anggakusuma, C.C. Colpitts, L.M. Schang, H. Rachmawati and A. Frentzen et al., 2013. Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut, 63: 1035-1037.
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  37. Susilo, R.A., Y.C. Sumirtapura, H. Rachmawati, S.T. Darijanto, D.S. Retnoningrum and L.B.S. Kardono, 2012. Over production of human recombinant interferon α-2b: Scaling up process. J. Applied Sci., 12: 1613-1617.
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  38. Rachmawati, H., P.L. Febrina, R.A. Ningrum and D. Sofieretnoningrum, 2012. The Influence of polyethylene glycol structure on the conjugation of recombinant human interferon α2b overproduced using synthetic gene in Eschericia coli. Int. J. Res. Pharm. Sci., 3: 228-233.
  39. Ningrum, R.A., D.E. Rahmatika, D.S. Retnoningrum, Y.C. Sumirtapura, A.H. Wangsaatmadja and H. Rachmawati, 2012. Development of novel interferon alpha2b muteins and study the pharmacokinetic and biodistribution profiles in animal model. J. Biomed. Sci. Eng., 5: 104-112.
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  40. Rachmawati, H., L. Beljaars, C. Reker-Smit, H.I. Bakker, A.M. Van Loenen-Weemaes, M.N. Lub-De Hooge and K. Poelstra, 2011. Intravenous administration of recombinant human IL-10 suppresses the development of anti-thy 1-induced glomerulosclerosis in rats. PDA J. Pharm. Sci. Technol., 65: 116-130.
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  41. Mozef, T., A.A.Soemardji, E.Y. Sukandar and H. Rachmawati, 2011. Potency of flavonoid from sukun (Artocarpus altilis) in inhibition of platelet aggregation in hyperaggregative subjects. Med. Plants-Int. J. Phytomed. Related Ind., 3: 307-310.
  42. Retnoningrum, D.S., R.A. Ningrum, Y.N. Kurniawan, A. Indrayati and H. Rachmawati, 2010. Construction of synthetic open reading frame encoding human interferon alpha 2b for high expression in E. coli and characterization of its gene product. J. Biotechnol., 145: 193-198.
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  43. Rachmawati, H., L. Beljaars, C.R. Smit, H.I. Bakker, D.F. Meijer and K. Poelstra, 2009. A study of the effects of interleukin-10 in anti-Thy 1-induced glomerulonephritis in rats. Int. J. Pharmacol., 5: 346-353.
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  44. Rachmawati, H., L. Beljaars, C.R. Smit, H.I. Bakker, D.F. Meijer and K. Poelstra, 2007. IL-10 modified with mannose 6-phosphate yields a liver-selective cytokine. Drug Metab. Dispos., 35: 814-821.
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  45. Asyarie, S. and H. Rachmawati, 2007. In vitro and in vivo evaluation of solid dispersion system of gliclazide: PEG 6000. PDA J. Pharmaceutical Sci. Technol., 61: 400-410.
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  46. Rachmawati, H., L. Beljaars, C.R. Smit, W.I. Hagens, D.F. Meijer and K. Poelstra, 2004. Pharmacokinetic and Biodistribution profile of recombinant human interleukin-10 in rats with extensive liver fibrosis. Pharmaceutical res., 21: 2072-2078.
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  47. Rachmawati, H., D. Mudhakir and J. Kusuma, 2001. Combination of inulin-shellac as a unique coating formulation for design of colonic delivery dosage form of ibuprofen. Int. J. Res. Pharm. Sci., 2: 1-7.