Dr. Jutti Levita
My Social Links

Dr. Jutti Levita

Lecturer
Department of Pharmacology and Clinical Pharmacy, Universitas Padjadjaran, Indonesia

Highest Degree
Ph.D. in Pharmacochemistry from Bandung Institute of Technology, Indonesia

Share this Profile

Biography

Prof. Jutti Levita is working as a senior lecturer at the Department of Pharmacology and Clinical Pharmacy, Universitas Padjadjaran, Indonesia. She obtained her Ph.D. in Pharmacochemistry from Bandung Institute of Technology, Indonesia. Her main area of interest related to Molecular Pharmacology, Structure-based Drug Design, Plant-based Drug Discovery. She is the author and co-author of 25 articles in Scopus-indexed journals.

Area of Interest:

Pharmacology and Toxicology
100%
Pharmacology
62%
Medicinal Plant Research
90%
Drug Discovery and Molecular Design
75%
Anti-Inflammatory Activities
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
49
Abstracts
0

Selected Publications

  1. Ramadhani, J., M. Mutakin, D.A. Perwitasari and J. Levita, 2020. Quality of life of patients receiving a single or combination of calcium channel blocker-angiotensin receptor blocker: A cross-sectional study in West Java, Indonesia J. App. Pharm. Sci., 10: 88-92.
    CrossRef  |  Direct Link  |  
  2. Levita, J., A.M. Rosdianto, I.M. Puspitasar and R. Lesmana, 2020. Determination of quercetin and flavonol synthase in boesenbergia rotunda rhizome. Pak. J. Biol. Sci., 23: 264-270.
    CrossRef  |  Direct Link  |  
  3. Aulifa, D.L., I.K. Adnyana, Sukrasno and J. Levita, 2020. Updates on 4-hydroxyderricin and xanthoangelol of angelica plants: extraction and pharmacological activities. Rasayan J. Chem., 13: 11-17.
    CrossRef  |  Direct Link  |  
  4. Sumiwi, S.A., A. Zuhrotun, R. Hendriani, M. Rizal, J. Levita and S. Megantara, 2019. Subchronic toxicity of ethanol extract of Syzygium polyanthum (Wight) Walp. Leaves on Wistar rat. Indones. Biomed. J., 11: 3-5.
    CrossRef  |  Direct Link  |  
  5. Aulifa, D.L., I.K. Adnyana, J. Levita and S. Sukrasno, 2019. 4-hydroxyderricin isolated from the sap of angelica keiskei koidzumi: Evaluation of its inhibitory activity towards dipeptidyl peptidase-IV. Sci. Pharm., 10.3390/scipharm87040030.
    CrossRef  |  Direct Link  |  
  6. Megantara, S., H. Halimah, A. Putrianty, D.H. Tjahjono, R.E. Kartasasmita, M.I. Iwo, J. Levita and S. Ibrahim, 2018. Microwave-assisted synthesis of hydroxybenzylidene-andrographolides and Its inhibitory activity against HIV-1 protease. J. Appl. Pharm. Sci., 10.7324/JAPS.2018.8302.
    CrossRef  |  Direct Link  |  
  7. Liem, S., T. Rostinawati, R. Lesmana, S.A. Sumiwi and T. Milanda et al., 2018. Modulation of caspase-3 expression by Arcangelisia flava post acetaminophen-induced hepatotoxicity in rat’s liver. Indones. Biomed. J., 10: 148-155.
    CrossRef  |  Direct Link  |  
  8. Levita, J., R. Patala, J. Kolina, T. Milanda and M. Mutakin et al., 2018. Pharmacophore modeling and molecular docking of phytoconstituents in Morus sp. and Arcangelisia flava against nitric oxide synthase for antiinflammatory discovery. J. Appl. Pharm. Sci., 8: 53-59.
    CrossRef  |  Direct Link  |  
  9. Levita, J., D. Syafitri, R. Supu, M. Mutakin, S. Megantara, M. Febrianti and A. Diantini, 2018. Pharmacokinetics of 10‑gingerol and 6‑shogaol in the plasma of healthy subjects treated with red ginger (Zingiber officinale var. Rubrum) suspension. Biom. Rep., 10.3892/br.2018.1163.
    CrossRef  |  Direct Link  |  
  10. Juwita, T., I.M. Puspitasari and J. Levita, 2018. Torch ginger (Etlingera elatior): A review on its botanical aspects, phytoconstituents and pharmacological activities. Pak. J. Biol. Sci., 21: 151-165.
    CrossRef  |  Direct Link  |  
  11. Saputri, F.A., M. Mutakin, K. Lestari and J. Levita, 2017. Development and validation of RP-HPLC method to determine DDIE, myristicin and safrole in ethanol extract of nutmeg (Myristica fragrans). Res. J. Pharm. Biol. Chem. Sci., 8: 75-79.
  12. Megantara, S., D.H. Tjahjono, R.E. Kartasasmita, M.I. Iwo, J. Levita and S. Ibrahim, 2017. In silico study of andrographolide and its derivates as HIV-1 protease inhibitors. Res. J. Pharm. Biol. Chem. Sci., 8: 222-228.
  13. Levita, J., T. Juwita, S. Ramadhani, N.M. Saptarini and M. Mutakin, 2017. Chromatogram profiles of andrographolide in A23187-induced New Zealand rabbit's urine and faeces. J. Applied Pharm. Sci., 7: 156-159.
    Direct Link  |  
  14. Levita, J., M.R. Rositama, N. Alias, N. Khalida, M. Saptarini and S. Megantara, 2017. Selectivity of plants' flavonoids and diterpenoids in inhibiting COX-2 enzyme for anti-inflammatory discovery. J. Applied Pharm. Sci., 7: 103-110.
  15. Baroroh, U., M. Yusuf, S.D. Rachman, S. Ishmayana, M.R.A.A. Syamsunarno, J. Levita and T. Subroto, 2017. The importance of surface-binding site towards starch-adsorptivity level in α-amylase: A review on structural point of view. Enzyme Res., 2017: 1-11.
    CrossRef  |  Direct Link  |  
  16. Megantara, S., M.I. Iwo, J. Levita and S. Ibrahim, 2016. Determination of ligand position in aspartic proteases by correlating Tanimoto coefficient and binding affinity with root mean square deviation. J. Applied Pharm. Sci., 6: 125-129.
    Direct Link  |  
  17. Mardhatillah, A., M. Mutakin and J. Levita, 2016. FeCl3-catalyzed synthesis of dehydrodiisoeugenol. Int. J. Chem., Vol. 8. 10.5539/ijc.v8n1p1.
    CrossRef  |  
  18. Levita, J., S.A. Sumiwi, T.I. Pratiwi, E. Ilham, S.P. Sidiq and M. Moektiwardoyo, 2016. Pharmacological Activities of Plectranthus scutellarioides (L.) R.Br. leaves extract on cyclooxygenase and xanthine oxidase enzymes. J. Med. Plant Res., 10: 261-269.
  19. Sumiwi, S.A., O.S. Sihombing, A. Subarnas, M. Abdassah and J. Levita, 2015. A study to predict anti-inflammatory activity of eugenol, myristicin and limonene of cinnamomum sintoc. Int. J. Pharm. Pharm. Sci., 7: 51-54.
  20. Siswandi, S., Mutakin and J. Levita, 2015. Virtual screening of co-formers for ketoprofen co- crystallization and the molecular properties of the co-crystal. J. Applied Pharm. Sci., 5: 78-82.
  21. Rahmania, H., A. Mutalib, M. Ramli and J. Levita, 2015. Synthesis and stability test of radiogadolinium (III)-DOTA-PAMAM G3.0-trastuzumab as SPECT-MRI molecular imaging agent for diagnosis of HER-2 positive breast cancer. J. Radiat. Res. Applied Sci., 8: 91-99.
    CrossRef  |  Direct Link  |  
  22. Levita, J., L.K. Wijaya, S. Celcilia and Dan Mutakin, 2015. Inhibitory activity of Kaempferia galanga and Hibiscus sabdariffa on the rate of PGH2 formation. J. Applied Sci., 15: 1032-1036.
  23. Kang, D., M. Mutakin and J. Levita, 2015. Computational study of triterpenoids of Ganoderma lucidum with aspartic protease enzymes for discovering HIV-1 and plasmepsin inhibitors. Int. J. Chem., 7: 62-68.
    CrossRef  |  Direct Link  |  
  24. Sumiwi, S.A., Y. Susilawati, A. Muhtadi, M. Abdassah, J. Levita and A. Subarnas, 2014. Anti-inflammatory and analgesic activity of Mimosa pudica herb extract. Int. J. Pharmacy Pharma. Res., 1: 6-12.
    Direct Link  |  
  25. Saputri, F.A., M. Mutakin, K. Lestari and J. Levita, 2014. Determination of safrole in ethanol extract of nutmeg (Myristica fragrans Houtt) using reversed-phase high performance liquid chromatography. Int. J. Chem., 6: 14-20.
    CrossRef  |  Direct Link  |  
  26. Saptarini, N.M., F.A. Saputri and J. Levita, 2014. Molecular modeling study of PPARγ agonists: Dehydro-Di-isoeugenol, macelignan, pioglitazone, netoglitazone and rosiglitazone as antidiabetic drugs. Int. J. Chem., 6: 48-55.
    CrossRef  |  Direct Link  |  
  27. Levita, J., K.H. Chao and Mutakin, 2014. Interactions of ganoderiol-F with aspartic proteases of HIV and plasmepsin for anti-HIV and antimalaria discovery. Int. J. Pharm. Pharmaceut. Sci., 6: 561-566.
    Direct Link  |  
  28. Levita, J., H. Himawati, R.V. Lukman, M. Afdila and H. Abdul Holik et al., 2014. Bioavailability study of sambiloto (Andrographis paniculata) herbs infusion in rabbit. Indonesian J. Pharm., 25: 138-144.
    CrossRef  |  Direct Link  |  
  29. Saptarini, N.M., E.Y. Sitorus and J. Levita, 2013. Structure-based in silico study of 6-gingerol, 6-ghogaol and 6-paradol, active compounds of ginger (Zingiber officinale) as COX-2 inhibitors. Int. J. Chem., 5: 12-18.
    CrossRef  |  Direct Link  |  
  30. Muchtaridi, M., J. levita , D. Rahayu and H. Rahmi, 2012. Influence of using coconut, palm, and corn oils as frying medium on concentration of acrylamide in fried tempe. Food Public Health, 2: 16-20.
    CrossRef  |  Direct Link  |  
  31. Levita, J., S. Megantara and Mutakin, 2012. Photometric titration method to determine bromination of red and yellow dyes in crackers. Int. J. Chem., 4: 80-85.
    CrossRef  |  Direct Link  |  
  32. Levita, J., N.M. Saptarini and A. Ardiansyah, 2012. Generating a 3D structure model of histamine-4 receptor for antiinflammatory drug design. E3 J. Biotechnol. Pharm. Res., 3: 22-27.
    Direct Link  |  
  33. Diantini, A., A. Subarnas, Supriyatna, J. Levita and R. Abdulah et al., 2012. Cytotoxicity of fevicordin-A from Phaleria macrocarpa (Scheff.) Boerl on P 388, HeLa, CasKi, TE-2, TE-8 and prepuce's fibroblast cells. E3 J. Med. Res., 1: 1-5.
    Direct Link  |  
  34. Mustarichie, R., J. Levita, I. Musfiroh and M. Moektiwardoyo, 2011. Determination of genistein in the fermented by-product of soybean curd, an Indonesian food and its in vivo assay on carrageenan-induced mice. J. Food Sci. Eng., 1: 80-84.
    Direct Link  |  
  35. Muchtaridi, A. Mutalib, J. Levita, A. Diantini and I. Musfiroh, 2011. [Prediction of antibreast cancer activity of fevicordin from Phaleria macrocarpa (Scheff) Boerl. seeds against Estrogen Receptor-α (ERα) by using quantitative structure activity relationship method]. Jurnal Bionatura, 13: 40-46, (In Indonesian).
    Direct Link  |  
  36. Moektiwardoyo, M., J. Levita, S.P. Sidiq, K. Ahmad, R. Mustarichie, A. Subarnas and S. Supriyatna, 2011. The determination of quercetin in Plectranthus scutellarioides (L.) R. Br. leaves extract and its in silico study on histamine H4 receptor. Indonesian J. Pharm., 22: 191-196.
    Direct Link  |  
  37. Levita, J., N.M. Widiastuti, I. Nugrahani, A. Musadad and A. Nawawi et al., 2011. Indirect iodination on the vinyl double bond of andrographolide. Int. J. Chem., 3: 47-56.
    CrossRef  |  Direct Link  |  
  38. Levita, J., D. Rahayu, N.M. Saptarini, A. Nawawi, A. Mutalib and S. Ibrahim, 2011. The inhibition of andrographolide (Andrographis paniculata) on the expression of carbonic anhydrase in LPS-induced human leucocyte cells. Asian J. Plant Sci., 10: 162-165.
    CrossRef  |  Direct Link  |  
  39. Hasanah, A.N., J. Levita, E.D. Natapoera and A. Subarnas, 2011. Analyzing the interaction of shellegueain A: A bioactive compound of pakis tangkur (Selliguea feei or Polypodium feei) to cyclooxygenase enzyme by molecular docking. Asian J. Chem., 23: 3093-3096.
    Direct Link  |  
  40. Levita, J., I. Musfiroh, W. Indriyati and R. Mustarichie, 2010. The effect of soaking, washing and frying on the concentration of formaldehyde in Sange Belah salty fish. Jurnal Bionatura, 12: 97-104.
  41. Levita, J., A. Nawawi, A. Mutholib and S. Ibrahim, 2010. Andrographolide inhibits COX-2 expression in human fibroblast cells due to its interaction with arginine and histidine in cyclooxygenase site. J. Applied Sci., 10: 1481-1484.
    CrossRef  |  Direct Link  |  
  42. Levita, J., A. Nawawi, A. Mutalib and S. Ibrahim, 2010. Andrographolide: A review of its anti-inflammatory activity via inhibition of NF-kappaB activation from computational chemistry aspects. Int. J. Pharmacol., 6: 569-576.
    CrossRef  |  Direct Link  |  
  43. Levita, J., E.P. Istyastono, A. Nawawi, A. Mutholib, I.J.P. de Esch and S. Ibrahim, 2009. Analyzing the interaction of andrographolide and neoandrographolide, diterpenoid compounds from Andrographis paniculata (Burm.F) nees, to cyclooxygenase-2 enzyme by docking simulation. ITB J. Sci., 41: 110-119.
    CrossRef  |  Direct Link  |