Dr. Emad Abd El-Aziz El-Sayed Rakha
My Social Links

Dr. Emad Abd El-Aziz El-Sayed Rakha

Professor and Consultant Pathologist
University of Nottingham, UK

Highest Degree
Ph.D. in Breast Pathology from University of Nottingham, UK

Share this Profile

Area of Interest:

Biomedical Sciences
100%
Oncology
62%
Breast Pathology
90%
Histopathology
75%
Cancer Research
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Roxanis, I., R. Colling, C. Kartsonaki, A.R. Green and E.A. Rakha, 2018. The significance of tumour microarchitectural features in breast cancer prognosis: A digital image analysis. Breast Cancer Res., Vol. 20. 10.1186/s13058-018-0934-x.
    CrossRef  |  Direct Link  |  
  2. Rakha, E.A., I. Miligy, K.L. Gorringe, M.S. Toss and A.R. Green et al., 2018. Invasion in breast lesions: The role of the epithelial-stroma barrier. Histopathology, 72: 1075-1083.
    CrossRef  |  Direct Link  |  
  3. Rakha, E.A. and I.O. Ellis, 2018. Diagnostic challenges in papillary lesions of the breast. Pathology, 50: 100-110.
    CrossRef  |  Direct Link  |  
  4. Pu, X., S.J. Storr, N.S. Ahmad, E.A. Rakha, A.R. Green, I.O. Ellis and S.G. Martin, 2018. High nuclear MSK1 is associated with longer survival in breast cancer patients. J. Cancer Res. Clin. Oncol., 144: 509-517.
    CrossRef  |  Direct Link  |  
  5. Naidoo, K., P.T. Wai, S.L. Maguire, F. Daley and S. Haider et al., 2018. Evaluation of CDK12 protein expression as a potential novel biomarker for DNA damage response-targeted therapies in breast cancer. Mol. Cancer Therapeut., 17: 306-315.
    CrossRef  |  Direct Link  |  
  6. El Ansari, R., M.L. Craze, M. Diez-Rodriguez, C.C. Nolan, I.O. Ellis, E.A. Rakha and A.R. Green, 2018. The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes. Br. J. Cancer, 118: 1115-1122.
    CrossRef  |  Direct Link  |  
  7. El Ansari, R., M.L. Craze, I. Miligy, M. Diez-Rodriguez and C.C. Nolan et al., 2018. The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours. Breast Cancer Res., Vol. 20. 10.1186/s13058-018-0946-6.
    CrossRef  |  Direct Link  |  
  8. El Ansari, R., A. McIntyre, M.L. Craze, I.O. Ellis, E.A. Rakha and A.R. Green, 2018. Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations. Histopathology, 72: 183-190.
    CrossRef  |  Direct Link  |  
  9. Ebili, H.O., V.O. Iyawe, K.R. Adeleke, B.A. Salami and A.A. Banjo et al., 2018. Checkpoint kinase 1 expression predicts poor prognosis in Nigerian breast cancer patients. Mol. Diagn. Therapy, 22: 79-90.
    CrossRef  |  Direct Link  |  
  10. Craze, M.L., H. Cheung, N. Jewa, N.D. Coimbra and D. Soria et al., 2018. MYC regulation of glutamine-proline regulatory axis is key in luminal B breast cancer. Br. J. Cancer, 118: 258-265.
    CrossRef  |  Direct Link  |  
  11. Aleskandarany, M.A., M.E. Vandenberghe, C. Marchio, I.O. Ellis, A. Sapino and E.A. Rakha, 2018. Tumour heterogeneity of breast cancer: From morphology to personalised medicine. Pathobiology, 85: 23-34.
    CrossRef  |  Direct Link  |  
  12. Al-Subhi, N., R. Ali, T. Abdel-Fatah, P.M. Moseley and S.Y. Chan et al., 2018. Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy. Breast Cancer Res. Treat., 169: 277-286.
    CrossRef  |  Direct Link  |  
  13. Ahmad, N., A. Ammar, S.J. Storr, A.R. Green, E. Rakha, I.O. Ellis and S.G. Martin, 2018. IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients. Cancer Immunol. Immunother., 67: 537-549.
    CrossRef  |  Direct Link  |  
  14. Toss, M.S., S.E. Pinder, A.R. Green, J. Thomas and D.A. Morgan et al., 2017. Breast conservation in ductal carcinoma in situ (DCIS): What defines optimal margins? Histopathology, 70: 681-692.
    CrossRef  |  Direct Link  |  
  15. Toss, M., I. Miligy, A.M. Thompson, H. Khout, A.R. Green, I.O. Ellis and E.A. Rakha, 2017. Current trials to reduce surgical intervention in ductal carcinoma in situ of the breast: Critical review. Breast, 35: 151-156.
    CrossRef  |  Direct Link  |  
  16. Sonbul, S.N., K.L. Gorringe, M.A. Aleskandarany, A. Mukherjee, A.R. Green, I.O. Ellis and E.A. Rakha, 2017. Chemokine (C-C motif) Receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma. J. Pathol.: Clin. Res., 3: 105-114.
    CrossRef  |  Direct Link  |  
  17. Rakha, E.A., R.L. Bennett, D. Coleman, S.E. Pinder and I.O. Ellis, 2017. Review of the national External Quality Assessment (EQA) scheme for breast pathology in the UK. J. Clin. Pathol., 70: 51-57.
    CrossRef  |  Direct Link  |  
  18. Rakha, E.A., N.D. Coimbra, Z. Hodi, E. Juneinah, I.O. Ellis and A.H. Lee, 2017. Immunoprofile of metaplastic carcinomas of the breast. Histopathology, 70: 975-985.
    CrossRef  |  Direct Link  |  
  19. Rakha, E.A., M.A. Ahmed, M.A. Aleskandarany, Z. Hodi, A.H. Lee, S.E. Pinder and I.O. Ellis, 2017. Diagnostic concordance of breast pathologists: Lessons from the National Health Service breast Screening Programme pathology external quality assurance scheme. Histopathology, 70: 632-642.
    CrossRef  |  Direct Link  |  
  20. Rakha, E.A., D. Agarwal, A.R. Green, I. Ashankyty, I.O. Ellis, G. Ball and M.A. Alaskandarany, 2017. Prognostic stratification of oestrogen receptor-positive HER2-negative lymph node-negative class of breast cancer. Histopathology, 70: 622-631.
    CrossRef  |  Direct Link  |  
  21. Pu, X., S.J. Storr, Y. Zhang, E.A. Rakha, A.R. Green, I.O. Ellis and S.G. Martin, 2017. Caspase-3 and caspase-8 expression in breast cancer: Caspase-3 is associated with survival. Apoptosis, 22: 357-368.
    CrossRef  |  Direct Link  |  
  22. Muftah, A.A., M.A. Aleskandarany, M.M. Al-Kaabi, S.N. Sonbul and M. Diez-Rodriguez et al., 2017. Ki67 expression in invasive breast cancer: The use of tissue microarrays compared with whole tissue sections. Breast Cancer Res. Treat., 164: 341-348.
    CrossRef  |  Direct Link  |  
  23. Muftah, A.A., M. Aleskandarany, S.N. Sonbul, C.C. Nolan and M.D. Rodriguez et al., 2017. Further evidence to support bimodality of oestrogen receptor expression in breast cancer. Histopathology, 70: 456-465.
    CrossRef  |  Direct Link  |  
  24. Mittal, K., D.H. Choi, A. Ogden, S. Donthamsetty and B.D. Melton et al., 2017. Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells. Scient. Rep., Vol. 7. 10.1038/srep43984.
    CrossRef  |  Direct Link  |  
  25. Miligy, I., P. Mohan, A. Gaber, M.A. Aleskandarany and C.C. Nolan et al., 2017. Prognostic significance of tumour infiltrating B lymphocytes in breast ductal carcinoma in situ. Histopathology, 71: 258-268.
    CrossRef  |  Direct Link  |  
  26. Metzler, V.M., S. de Brot, R.S. Robinson, J.N. Jeyapalan and E. Rakha et al., 2017. Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development. Placenta, 56: 79-85.
    CrossRef  |  Direct Link  |  
  27. Klimov, S., P.C. Rida, M.A. Aleskandarany, A.R. Green and I.O. Ellis et al., 2017. Novel immunohistochemistry-based signatures to predict metastatic site of triple-negative breast cancers. Br. J. Cancer, 117: 826-834.
    CrossRef  |  Direct Link  |  
  28. Green, A.R., M.A. Aleskandarany, R. Ali, E.G. Hodgson and S. Atabani et al., 2017. Clinical impact of tumor DNA repair expression and T-cell infiltration in breast cancers. Cancer Immunol. Res., 5: 292-299.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Geyer, F.C., S.H. Berman, C. Marchio, K.A. Burke and E. Guerini-Rocco et al., 2017. Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family. Mod. Pathol., 30: 69-84.
    CrossRef  |  Direct Link  |  
  30. Geyer, F.C., F. Pareja, B. Weigelt, E. Rakha, I.O. Ellis, S.J. Schnitt and J.S. Reis-Filho, 2017. The spectrum of triple-negative breast disease: High- and low-grade lesions. Am. J. Pathol., 187: 2139-2151.
    CrossRef  |  Direct Link  |  
  31. Dos Reis, F.J.C., G.C. Wishart, E.M. Dicks, D. Greenberg and J. Rashbass et al., 2017. An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation. Breast Cancer Res., Vol. 19. 10.1186/s13058-017-0852-3.
    CrossRef  |  Direct Link  |  
  32. Dahlstrom, J.E., E.A. Rakha, S.R. Lakhani and S.J. Schnitt, 2017. Current topics in breast pathology: Expert perspectives. Pathology, 49: 109-110.
    PubMed  |  
  33. Chrysanthou, E., K.L. Gorringe, C. Joseph, M. Craze and C.C. Nolan et al., 2017. Phenotypic characterisation of breast cancer: The role of CDC42. Breast Cancer Res. Treat., 164: 317-325.
    CrossRef  |  Direct Link  |  
  34. Arora, A., S. Parvathaneni, M.A. Aleskandarany, D. Agarwal and R. Ali et al., 2017. Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers. Mol. Cancer Therapeut., 16: 239-250.
    CrossRef  |  Direct Link  |  
  35. Ali, R., E.A. Rakha, S. Madhusudan and H.E. Bryant, 2017. DNA damage repair in breast cancer and its therapeutic implications. Pathology, 49: 156-165.
    CrossRef  |  Direct Link  |  
  36. Aleskandarany, M.A., S. Sonbul, R. Surridge, A. Mukherjee and C. Caldas et al., 2017. Rho-GTPase activating-protein 18: A biomarker associated with good prognosis in invasive breast cancer. Br. J. Cancer, 117: 1176-1178.
    CrossRef  |  Direct Link  |  
  37. Agboola, A.O., H.O. Ebili, V.O. Iyawe, A.A. Banjo and B.A. Salami et al., 2017. Clinicopathological and molecular characteristics of Ku 70/80 expression in Nigerian breast cancer and its potential therapeutic implications. Pathol.-Res. Pract., 213: 27-33.
    CrossRef  |  Direct Link  |  
  38. Tan, B.Y., G. Acs, S.K. Apple, S. Badve and I.J. Bleiweiss et al., 2016. Phyllodes tumours of the breast: A consensus review. Histopathology, 68: 5-21.
    CrossRef  |  Direct Link  |  
  39. Rakha, E.A., S. Badve, V. Eusebi, J.S. Reis‐Filho and S.B. Fox et al., 2016. Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management. Histopathology, 68: 45-56.
    CrossRef  |  Direct Link  |  
  40. Rakha, E.A., M.A. Aleskandarany, R.M. Samaka, Z. Hodi, A.H. Lee and I.O. Ellis, 2016. Pleomorphic adenoma‐like tumour of the breast. Histopathology, 68: 405-410.
    CrossRef  |  Direct Link  |  
  41. Rakha, E.A., M.A. Aleskandarany, A.H. Lee and I.O. Ellis, 2016. An approach to the diagnosis of spindle cell lesions of the breast. Histopathology, 68: 33-44.
    CrossRef  |  Direct Link  |  
  42. Rakha, E.A., M.A. Ahmed and I.O. Ellis, 2016. Papillary carcinoma of the breast: Diagnostic agreement and management implications. Histopathology, 69: 862-870.
    CrossRef  |  Direct Link  |  
  43. Rakha, E.A., M. Pigera, A. Shaaban, S.J. Shin, T. D'Alfonso, I.O. Ellis and A.H.S. Lee, 2016. HER2 testing in invasive breast cancer and discordance rate: A large multi-institutional study. Histopathology, 69: 20-24.
  44. Rakha, E.A., A. Abbas and R. Sheeran, 2016. Invasive lobular carcinoma mimicking papillary carcinoma: A report of three cases. Pathobiology, 83: 221-227.
    CrossRef  |  Direct Link  |  
  45. Rakha, E.A., 2016. Morphogenesis of the papillary lesions of the breast: Phenotypic observation. J. Clin. Pathol., 69: 64-69.
    CrossRef  |  Direct Link  |  
  46. Patel, H., R. Abduljabbar, C.F. Lai, M. Periyasamy and A. Harrod et al., 2016. Expression of CDK7, Cyclin H and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor-positive breast cancer. Clin. Cancer Res., 22: 5929-5938.
    CrossRef  |  Direct Link  |  
  47. Negm, O.H., A.A. Muftah, M.A. Aleskandarany, M.R. Hamed and D.A.J. Ahmad et al., 2016. Clinical utility of reverse phase protein array for molecular classification of breast cancer. Breast Cancer Res. Treat., 155: 25-35.
    CrossRef  |  Direct Link  |  
  48. Laurinavicius, A., B. Plancoulaine, A. Rasmusson, J. Besusparis and R. Augulis et al., 2016. Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinoma. Virchows Archiv, 468: 493-502.
    CrossRef  |  Direct Link  |  
  49. Langlands, F., E. Cornford, E. Rakha, B. Dall and E. Gutteridge et al., 2016. Imaging overview of metaplastic carcinomas of the breast: A large study of 71 cases. Br. J. Radiol., Vol. 89. 10.1259/bjr.20140644.
    CrossRef  |  Direct Link  |  
  50. Guerini-Rocco, E., S. Piscuoglio, C.K.Y. Ng, F.C. Geyer and M.R. de Filippo et al., 2016. Microglandular adenosis associated with triple-negative breast cancer is a neoplastic lesion of triple-negative phenotype harbouring TP53 somatic mutations. J. Pathol., 238: 677-688.
    CrossRef  |  Direct Link  |  
  51. Griffin, N.I., G. Sharma, X. Zhao, S. Mirza and S. Srivastava et al., 2016. ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC. Breast Cancer Res., Vol. 18. 10.1186/s13058-016-0770-9.
    CrossRef  |  Direct Link  |  
  52. Green, A.R., M.A. Aleskandarany, D. Agarwal, S. Elsheikh and C.C. Nolan et al., 2016. MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours. Br. J. Cancer, 114: 917-928.
    CrossRef  |  Direct Link  |  
  53. Green, A.R., D. Soria, J. Stephen, D.G. Powe and C.C. Nolan et al., 2016. Nottingham prognostic index plus: Validation of a clinical decision making tool in breast cancer in an independent series. J. Pathol.: Clin. Res., 2: 32-40.
    CrossRef  |  Direct Link  |  
  54. Green, A.R., D. Soria, D.G. Powe, C.C. Nolan and M. Aleskandarany et al., 2016. Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer. Breast Cancer Res. Treat., 157: 65-75.
    CrossRef  |  Direct Link  |  
  55. Francis, A., J. Bartlett, D. Rea, S.E. Pinder and R.C. Stein et al., 2016. Availability of oestrogen receptor and HER2 status for the breast multidisciplinary meeting discussion; time to get it right. Eur. J. Surg. Oncol., 42: 994-998.
    CrossRef  |  Direct Link  |  
  56. Eberle, C.A., S. Piscuoglio, E.A. Rakha, C.K. Ng and F.C. Geyer et al., 2016. Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile. Histopathology, 68: 1030-1039.
    CrossRef  |  Direct Link  |  
  57. Bellerby, R., C. Smith, S. Kyme, J. Gee and U. Gunthert et al., 2016. Overexpression of specific cD44 isoforms is associated with aggressive cell features in acquired endocrine resistance. Front. Oncol., Vol. 6. 10.3389/fonc.2016.00145.
    CrossRef  |  PubMed  |  Direct Link  |  
  58. Arora, A., T.M.A. Abdel-Fatah, D. Agarwal, R. Doherty and D.L. Croteau et al., 2016. Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers. Carcinogenesis, 37: 63-71.
    CrossRef  |  Direct Link  |  
  59. Arora, A., D. Agarwal, T.M.A. Abdel-Fatah, H. Lu and D.L. Croteau et al., 2016. RECQL4 helicase has oncogenic potential in sporadic breast cancers. J. Pathol., 238: 495-501.
    CrossRef  |  Direct Link  |  
  60. Alsubhi, N., F. Middleton, T. Abdel-Fatah, P. Stephens and R. Doherty et al., 2016. Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio‐resistance in breast cancer. Mol. Oncol., 10: 213-223.
    CrossRef  |  Direct Link  |  
  61. Alshareeda, A.T., O.H. Negm, M.A. Aleskandarany, A.R. Green and C. Nolan et al., 2016. Clinical and biological significance of RAD51 expression in breast cancer: A key DNA damage response protein. Breast Cancer Res. Treat., 159: 41-53.
    CrossRef  |  Direct Link  |  
  62. Aleskandarany, M.A., R. Abduljabbar, I. Ashankyty, A. Elmouna and D. Jerjees et al., 2016. Prognostic significance of androgen receptor expression in invasive breast cancer: Transcriptomic and protein expression analysis. Breast Cancer Res. Treat., 159: 215-227.
    CrossRef  |  Direct Link  |  
  63. Aleskandarany, M.A., D. Agarwal, O.H. Negm, G. Ball and A. Elmouna et al., 2016. The prognostic significance of STAT3 in invasive breast cancer: Analysis of protein and mRNA expressions in large cohorts. Breast Cancer Res. Treat., 156: 9-20.
    CrossRef  |  Direct Link  |  
  64. Aleskandarany, M.A., A.R. Green, I. Ashankyty, A. Elmouna and M. Diez-Rodriguez et al., 2016. Impact of intratumoural heterogeneity on the assessment of Ki67 expression in breast cancer. Breast Cancer Res. Treat., 158: 287-295.
    CrossRef  |  Direct Link  |  
  65. Albanghali, M., A. Green, E. Rakha, M. Aleskandarany, C. Nolan, I. Ellis and K.L. Cheung, 2016. Construction of tissue microarrays from core needle biopsies-a systematic literature review. Histopathology, 68: 323-332.
    CrossRef  |  Direct Link  |  
  66. Ahmad, D.A.J., O.H. Negm, M.L. Alabdullah, S. Mirza and M.R. Hamed et al., 2016. Clinicopathological and prognostic significance of Mitogen-Activated Protein Kinases (MAPK) in breast cancers. Breast Cancer Res. Treat., 159: 457-467.
    CrossRef  |  Direct Link  |  
  67. Agboola, A.O.J., H.O. Ebili, V.O. Iyawe, A.A.F. Banjo and B.S. Salami et al., 2016. Tumour cell membrane laminin expression is associated with basal-like phenotype and poor survival in Nigerian breast cancer. Malays. J. Pathol., 38: 83-92.
    PubMed  |  Direct Link  |  
  68. Agboola, A., H. Ebili, V. Iyawe, A. Banjo and B. Salami et al., 2016. Relevance of the MicroRNA (Mirna) processor DICER expression in the biological behaviour and pathological response of Nigerian breast cancer tissues. Ann. Health Res., 2: 44-51.
    Direct Link  |  
  69. Wolff, A.C., M.E. Hammond, D.G. Hicks, K.H. Allison and J.M. Bartlett et al., 2015. Reply to E.A. Rakha et al. J. Clin. Oncol., 33: 1302-1303.
    CrossRef  |  Direct Link  |  
  70. Rea, D., A. Francis, A.M. Hanby, V. Speirs and E. Rakha et al., 2015. Inflammatory breast cancer: Time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research. Br. J. Cancer, 112: 1613-1615.
    CrossRef  |  Direct Link  |  
  71. Rakha, E.A., Z. Varga, S. Elsheik and I.O. Ellis, 2015. High‐grade encapsulated papillary carcinoma of the breast: An under‐recognized entity. Histopathology, 66: 740-746.
    CrossRef  |  Direct Link  |  
  72. Rakha, E.A., S.E. Pinder, J.M. Bartlett, M. Ibrahim and J. Starczynski et al., 2015. Updated UK Recommendations for HER2 assessment in breast cancer. J. Clin. Pathol., 68: 93-99.
    CrossRef  |  Direct Link  |  
  73. Rakha, E.A., P.H. Tan, Z. Varga, G.M. Tse and A.M. Shaaban et al., 2015. Prognostic factors in metaplastic carcinoma of the breast: A multi-institutional study. Br. J. Cancer, 112: 283-289.
    CrossRef  |  Direct Link  |  
  74. Rakha, E.A., M. Pigera, A. Shaaban, S.J. Shin, T. D'Alfonso, I.O. Ellis and A.H. Lee, 2015. National guidelines and level of evidence: Comments on some of the new recommendations in the American society of clinical oncology and the college of American pathologists human epidermal growth factor receptor 2 guidelines for breast cancer. J. Clin. Oncol., 33: 1301-1302.
    CrossRef  |  Direct Link  |  
  75. Rakha, E.A., A.H. Lee, R. Sheeran, C. Abbosh and Z. Hodi et al., 2015. Breast neoplasms with dermal analogue differentiation (mammary cylindroma): Report of 3 cases and a proposal for a new terminology. Pathobiology, 82: 172-178.
    CrossRef  |  Direct Link  |  
  76. Rakha, E., M.J. Pajares, M. Ilie, R. Pio and J. Echeveste et al., 2015. Stratification of resectable lung adenocarcinoma by molecular and pathological risk estimators. Eur. J. Cancer, 51: 1897-1903.
    CrossRef  |  Direct Link  |  
  77. Piscuoglio, S., Z. Hodi, N. Katabi, E. Guerini-Rocco and G.S. Macedo et al., 2015. Are acinic cell carcinomas of the breast and salivary glands distinct diseases? Histopathology, 67: 529-537.
    CrossRef  |  Direct Link  |  
  78. Pinder, S.E., E.A. Rakha, C.A. Purdie, J. Bartlett and A. Francis et al., 2015. Macroscopic handling and reporting of breast cancer specimens pre‐and post‐neoadjuvant chemotherapy treatment: Review of pathological issues and suggested approaches. Histopathology, 67: 279-293.
    CrossRef  |  Direct Link  |  
  79. Ong, C.C., S. Gierke, C. Pitt, M. Sagolla and C.K. Cheng et al., 2015. Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents. Breast Cancer Res., Vol. 17. 10.1186/s13058-015-0564-5.
    CrossRef  |  Direct Link  |  
  80. Nelson, L., H.D. McKeen, A. Marshall, L. Mulrane and J. Starczynski et al., 2015. FKBPL: A marker of good prognosis in breast cancer. Oncotarget, 6: 12209-12223.
    CrossRef  |  Direct Link  |  
  81. Magnani, L., D.K. Patten, V.T. Nguyen, S.P. Hong and J.H. Steel et al., 2015. The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer. Oncotarget, 6: 21878-21891.
    CrossRef  |  Direct Link  |  
  82. Lee, A.H., E.A. Rakha and I.O. Ellis, 2015. Brief fixation and hormone receptor expression in breast cancer. Am. J. Surg. Pathol., 39: 425-425.
    CrossRef  |  Direct Link  |  
  83. Jerjees, D.A., O.H. Negm, M.L. Alabdullah, S. Mirza and M. Alkaabi et al., 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: The impact of oestrogen receptor and HER2 pathways. Breast Cancer Res. Treat., 150: 91-103.
    CrossRef  |  Direct Link  |  
  84. Guerini‐Rocco, E., Z. Hodi, S. Piscuoglio, C.K. Ng and E.A. Rakha et al., 2015. The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: An exploratory, hypothesis‐generating study. J. Pathol., 237: 166-178.
    CrossRef  |  Direct Link  |  
  85. Green, A.R., D. Caracappa, A.A. Benhasouna, A. Alshareeda and C.C. Nolan et al., 2015. Biological and clinical significance of PARP1 protein expression in breast cancer. Breast Cancer Res. Treat., 149: 353-362.
    CrossRef  |  Direct Link  |  
  86. Gale, K.L., E.A. Rakha, G. Ball, V.K. Tan, S.J. McCulley and R.D. Macmillan, 2015. A case-controlled study of the oncologic safety of fat grafting. Plastic Reconstructive Surg., 135: 1263-1275.
    CrossRef  |  Direct Link  |  
  87. Arora, A., T.M. Abdel-Fatah, D. Agarwal, R. Doherty and P.M. Moseley et al., 2015. Transcriptomic and protein expression analysis reveals clinicopathological significance of bloom syndrome helicase (BLM) in breast cancer. Mol. Cancer Ther., 14: 1057-1065.
    CrossRef  |  Direct Link  |  
  88. Alshareeda, A.T., O.H. Negm, A.R. Green, C.C. Nolan and P. Tighe et al., 2015. KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer. Br. J. Cancer, 112: 1929-1937.
    CrossRef  |  Direct Link  |  
  89. Aleskandarany, M.A., S.N. Sonbul, A. Mukherjee and E.A. Rakha, 2015. Molecular mechanisms underlying lymphovascular invasion in invasive breast cancer. Pathobiology, 82: 113-123.
    CrossRef  |  Direct Link  |  
  90. Aleskandarany, M.A., D. Soria, A.R. Green, C. Nolan, M. Diez-Rodriguez, I.O. Ellis and E.A. Rakha, 2015. Markers of progression in early-stage invasive breast cancer: A predictive immunohistochemical panel algorithm for distant recurrence risk stratification. Breast Cancer Res. Treat., 151: 325-333.
    CrossRef  |  Direct Link  |  
  91. Aleskandarany, M., D. Caracappa, C.C. Nolan, R.D. Macmillan, I.O. Ellis, E.A. Rakha and A.R. Green, 2015. DNA damage response markers are differentially expressed in BRCA-mutated breast cancers. Breast Cancer Res. Treat., 150: 81-90.
    CrossRef  |  Direct Link  |  
  92. Albarakati, N., T. Abdel-Fatah, R. Doherty, R. Russell and D. Agarwal et al., 2015. Targeting BRCA1‐BER deficient breast cancer by ATM or DNA‐PKcs blockade either alone or in combination with cisplatin for personalized therapy. Mol. Oncol., 9: 204-217.
    CrossRef  |  Direct Link  |  
  93. Al-Kaabi, M.M., A.T. Alshareeda, D.A. Jerjees, A.A. Muftah and A.R. Green et al., 2015. Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response. Br. J. Cancer, 112: 901-911.
    CrossRef  |  Direct Link  |  
  94. Abduljabbar, R., O.H. Negm, C.F. Lai, D.A. Jerjees and M. Al-Kaabi et al., 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer. Breast Cancer Res. Treat., 150: 335-346.
    CrossRef  |  Direct Link  |  
  95. Abduljabbar, R., M.M. Al-Kaabi, O.H. Negm, D. Jerjees and A.A. Muftah et al., 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer. Breast Cancer Res. Treat., 150: 511-522.
    CrossRef  |  Direct Link  |  
  96. Abdel-Fatah, T.M., A. Arora, P.M. Moseley, C. Perry and E.A. Rakha et al., 2015. DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers. Oncotarget, 6: 21964-21978.
    CrossRef  |  Direct Link  |  
  97. Abdel-Fatah, T., F.K. Middleton, A. Arora, D. Agarwal and T. Chen et al., 2015. Untangling the ATR‐CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer. Mol. Oncol., 9: 569-585.
    CrossRef  |  Direct Link  |  
  98. Zhang, Y., S.J. Storr, K. Johnson, A.R. Green and E.A. Rakha et al., 2014. Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy. Oncotarget, 5: 12936-12949.
    CrossRef  |  Direct Link  |  
  99. Wishart, G.C., E. Rakha, A. Green, I. Ellis and H.R. Ali et al., 2014. Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer. BMC Cancer, Vol. 14. 10.1186/1471-2407-14-908.
    CrossRef  |  Direct Link  |  
  100. Rakha, E.A., J. Starczynski, A.H. Lee and I.O. Ellis, 2014. The updated ASCO/CAP guideline recommendations for HER2 testing in the management of invasive breast cancer: A critical review of their implications for routine practice. Histopathology, 64: 609-615.
    CrossRef  |  Direct Link  |  
  101. Rakha, E.A., D. Soria, A.R. Green, C. Lemetre and D.G. Powe et al., 2014. Nottingham prognostic index plus (NPI+): A modern clinical decision making tool in breast cancer. Br. J. Cancer, 110: 1688-1697.
    CrossRef  |  Direct Link  |  
  102. Rakha, E.A. and I.O. Ellis, 2014. Breast cancer: Updated guideline recommendations for HER2 testing. Nat. Rev. Clin. Oncol., 11: 8-9.
    CrossRef  |  Direct Link  |  
  103. Kong, K., F. Zaabar, E. Rakha, I. Ellis, A. Koloydenko and I. Notingher, 2014. Towards intra-operative diagnosis of tumours during breast conserving surgery by selective-sampling Raman micro-spectroscopy. Phys. Med. Biol., 59: 6141-6152.
    CrossRef  |  Direct Link  |  
  104. Jerjees, D.A., M. Alabdullah, M. Alkaabi, R. Abduljabbar and A. Muftah et al., 2014. ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer. Breast Cancer Res. Treat., 147: 25-37.
    CrossRef  |  Direct Link  |  
  105. Jerjees, D.A., M. Alabdullah, A.R. Green, A. Alshareeda, R.D. Macmillan, I.O. Ellis and E.A. Rakha, 2014. Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer. Breast Cancer Res. Treat., 145: 317-330.
    CrossRef  |  Direct Link  |  
  106. Ho-Yen, C.M., A.R. Green, E.A. Rakha, A.R. Brentnall, I.O. Ellis, S. Kermorgant and J.L. Jones, 2014. C-Met in invasive breast cancer: Is there a relationship with the basal-like subtype? Cancer, 120: 163-171.
  107. Harrison, D., E. Rakha, A.R. Green, I.H. Kunkler and S. Wagner et al., 2014. Predicting chemotherapy response in invasive breast cancer. J. Clin. Oncol., 32: 1084-1084.
    CrossRef  |  Direct Link  |  
  108. Green, A.R., F.F. Barros, T.M. Abdel-Fatah, P. Moseley and C.C. Nolan et al., 2014. HER2/HER3 heterodimers and p21 expression are capable of predicting adjuvant trastuzumab response in HER2+ breast cancer. Breast Cancer Res. Treat., 145: 33-44.
    CrossRef  |  Direct Link  |  
  109. Davis, J., S.G. Martin, P.M. Patel, A.R. Green, E.A. Rakha, I.O. Ellis and S.J. Storr, 2014. Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer. BMC Cancer, Vol. 14. 10.1186/1471-2407-14-995.
    CrossRef  |  Direct Link  |  
  110. Barros, F.F., T.M. Abdel-Fatah, P. Moseley, C.C. Nolan and A.C. Durham et al., 2014. Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay. Breast Cancer Res. Treat., 144: 273-285.
    CrossRef  |  Direct Link  |  
  111. Alshareeda, A.T., O.H. Negm, A.R. Green, C. Nolan and P. Tighe et al., 2014. SUMOylation proteins in breast cancer. Breast Cancer Res. Treat., 144: 519-530.
    CrossRef  |  Direct Link  |  
  112. Ali, H.R., E. Provenzano, S.J. Dawson, F.M. Blows and B. Liu et al., 2014. Association between CD8+ T-cell infiltration and breast cancer survival in 12 439 patients. Ann. Oncol., 25: 1536-1543.
    CrossRef  |  Direct Link  |  
  113. Aleskandarany, M.A., O.H. Negm, A.R. Green, M.A. Ahmed and C.C. Nolan et al., 2014. Epithelial mesenchymal transition in early invasive breast cancer: An immunohistochemical and reverse phase protein array study. Breast Cancer Res. Treat., 145: 339-348.
    CrossRef  |  Direct Link  |  
  114. Agboola, A.O.J., A.A. Musa, B.A. Ayoade, A.A. Banjo and C.C. Anunobi et al., 2014. Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathol. Res. Pract., 210: 10-17.
    CrossRef  |  Direct Link  |  
  115. Agboola, A.O.J., A.A. Banjo, C.C. Anunobi, B.A. Ayoade and A.M. Deji-Agboola et al., 2014. Molecular profiling of breast cancer in Nigerian women identifies an altered p53 pathway as a major mechanism underlying its poor prognosis compared with British counterpart. Malaysian J. Pathol., 36: 3-17.
  116. Abdel-Fatah, T.M., A. Arora, N. Alsubhi, D. Agarwal and P.M. Moseley et al., 2014. Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: A comprehensive analysis in large cohorts. Neoplasia, 16: 982-991.
    CrossRef  |  Direct Link  |  
  117. Abdel-Fatah, T., A. Arora, D. Agarwal, P. Moseley and C. Perry et al., 2014. Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers. Breast Cancer Res. Treat., 146: 309-320.
    CrossRef  |  Direct Link  |  
  118. Sultana, R., T. Abdel-Fatah, R. Abbotts, C. Hawkes and N. Albarakati et al., 2013. Targeting XRCC1 deficiency in breast cancer for personalized therapy. Cancer Res., 73: 1621-1634.
    CrossRef  |  Direct Link  |  
  119. Rakha, E.A., T.K. Teoh, A.H. Lee, C.C. Nolan, I.O. Ellis and A.R. Green, 2013. Further evidence that E‐cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: An immunohistochemical study. Histopathology, 62: 695-701.
    CrossRef  |  Direct Link  |  
  120. Rakha, E.A., S.A. O'Toole, I.O. Ellis and P.H. Tan, 2013. Breast pathology today: Morphology and molecules. J. Clin. Pathol., 66: 457-457.
    CrossRef  |  Direct Link  |  
  121. Rakha, E.A., P.H. Tan, A. Shaaban, M.T. Gary and F.C. Esteller et al., 2013. Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours. Breast, 22: 13-18.
    CrossRef  |  Direct Link  |  
  122. Rakha, E.A., C.H. van Deurzen, E.C. Paish, R.D. Macmillan, I.O. Ellis and A.H. Lee, 2013. Pleomorphic lobular carcinoma of the breast: Is it a prognostically significant pathological subtype independent of histological grade? Modern Pathol., 26: 496-501.
    CrossRef  |  Direct Link  |  
  123. Rakha, E.A., A.M. Shaaban, S.A. Haider, J. Jenkins and S. Menon et al., 2013. Outcome of pure mucocele‐like lesions diagnosed on breast core biopsy. Histopathology, 62: 894-898.
    CrossRef  |  Direct Link  |  
  124. Rakha, E.A., 2013. Pitfalls in outcome prediction of breast cancer. J. Clin. Pathol., 66: 458-464.
    CrossRef  |  Direct Link  |  
  125. Rakha, E.A. and I.O. Ellis, 2013. Authors' reply: Combining two antibodies to define E‐cadherin loss of expression in non‐lobular breast carcinomas: When less is more. Histopathology, 63: 440-443.
    CrossRef  |  Direct Link  |  
  126. Mukherjee, A. and E.A. Rakha, 2013. Toward personalized breast cancer management: The role of lymphovascular invasion. J. Oncopathol., 1: 10-13.
  127. Mirza, S., E.A. Rakha, A. Alshareeda, S. Mohibi and X. Zhao et al., 2013. Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients. Breast Cancer Res. Treat., 137: 721-731.
    CrossRef  |  Direct Link  |  
  128. Khoshnaw, S.M., E.A. Rakha, T. Abdel-Fatah, C.C. Nolan and Z. Hodi et al., 2013. The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients. Breast Cancer Res. Treat., 137: 139-153.
    CrossRef  |  Direct Link  |  
  129. Habashy, H.O., E.A. Rakha, I.O. Ellis and D.G. Powe, 2013. The oestrogen receptor coactivator CARM1 has an oncogenic effect and is associated with poor prognosis in breast cancer. Breast Cancer Res. Treat., 140: 307-316.
    CrossRef  |  Direct Link  |  
  130. Green, A.R., D.G. Powe, E.A. Rakha, D. Soria and C. Lemetre et al., 2013. Identification of key clinical phenotypes of breast cancer using a reduced panel of protein biomarkers. Br. J. Cancer, 109: 1886-1894.
    CrossRef  |  Direct Link  |  
  131. Eccles, S.A., E.O. Aboagye, S. Ali, A.S. Anderson and J. Armes et al., 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res., Vol. 15. 10.1186/bcr3493.
    CrossRef  |  Direct Link  |  
  132. Dabbs, D.J., S.J. Schnitt, F.C. Geyer, B. Weigelt and F.L. Baehner et al., 2013. Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry. Am. J. Surg. Pathol., 37: e1-e11.
    CrossRef  |  Direct Link  |  
  133. Baker, B.G., G.R. Ball, E.A. Rakha, C.C. Nolan, C. Caldas, I.O. Ellis and A.R. Green, 2013. Lack of expression of the proteins GMPR2 and PPARα are associated with the basal phenotype and patient outcome in breast cancer. Breast Cancer Res. Treat., 137: 127-137.
    CrossRef  |  Direct Link  |  
  134. Alshareeda, A.T., O.H. Negm, N. Albarakati, A.R. Green and C. Nolan et al., 2013. Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer. Breast Cancer Res. Treat., 139: 301-310.
    CrossRef  |  Direct Link  |  
  135. Alshareeda, A.T., D. Soria, J.M. Garibaldi, E. Rakha, C. Nolan, I.O. Ellis and A.R. Green, 2013. Characteristics of basal cytokeratin expression in breast cancer. Breast Cancer Res. Treat., 139: 23-37.
    CrossRef  |  Direct Link  |  
  136. Agboola, A.O., A.A. Banjo, C.C. Anunobi, B. Salami and M.D. Agboola et al., 2013. Cell proliferation (KI-67) Expression is associated with poorer prognosis in Nigerian compared to British breast cancer women. ISRN Oncol., Vol. 2013. 10.1155/2013/675051.
    CrossRef  |  Direct Link  |  
  137. Agboola, A.J., A.A. Musa, N. Wanangwa, T. Abdel-Fatah and C.C. Nolan et al., 2013. Too many statistical errors for meaningful interpretation. Response to letter to the editor. Breast Cancer Res. Treat., 138: 645-650.
    PubMed  |  
  138. Agboola, A., A. Musa, A. Banjo, B. Ayoade and M. Deji-Agboola et al., 2013. PIASγ expression in relation to clinicopathological, tumour factors and survival in indigenous black breast cancer women. J. Clin. Pathol., 67: 301-306.
    CrossRef  |  Direct Link  |  
  139. Zhao, X., S. Mirza, A. Alshareeda, Y. Zhang and C.B. Gurumurthy et al., 2012. Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: A marker of poor prognosis in HER2/neu-overexpressing breast cancer patients. Breast Cancer Res. Treat., 134: 171-180.
    CrossRef  |  Direct Link  |  
  140. Yamaguchi, R., K. Maeshiro, I.O. Ellis, E.A. Rakha and J. Taguchi et al., 2012. Infiltrative epitheliosis of the breast. J. Clin. Pathol., 65: 766-768.
    CrossRef  |  Direct Link  |  
  141. Wishart, G.C., C.D. Bajdik, E. Dicks, E. Provenzano and M.K. Schmidt et al., 2012. PREDICT Plus: Development and validation of a prognostic model for early breast cancer that includes HER2. Br. J. Cancer, 107: 800-807.
    CrossRef  |  Direct Link  |  
  142. Rakha, E.A., S. Martin, A.H. Lee, D. Morgan and P.D. Pharoah et al., 2012. The prognostic significance of lymphovascular invasion in invasive breast carcinoma. Cancer, 118: 3670-3680.
    CrossRef  |  Direct Link  |  
  143. Rakha, E.A., M. Tun, E. Junainah, I.O. Ellis and A. Green, 2012. Encapsulated papillary carcinoma of the breast: A study of invasion associated markers. J. Clin. Pathol., 65: 710-714.
    CrossRef  |  Direct Link  |  
  144. Rakha, E.A., D. Morgan and D. Macmillan, 2012. The prognostic significance of early stage lymph node positivity in operable invasive breast carcinoma: Number or stage. J. Clin. Pathol., 65: 624-630.
    CrossRef  |  Direct Link  |  
  145. Rakha, E.A., D. Clark, B.S. Chohan, M. El-Sayed, S. Sen, L. Bakowski and S. O'Connor, 2012. Efficacy of an incident-reporting system in cellular pathology: A practical experience. J. Clin. Pathol., 65: 643-648.
    CrossRef  |  Direct Link  |  
  146. Rakha, E.A., A.H. Lee, J. Roberts, N.M.V. Salinas, Z. Hodi, I.O. Ellis and J.S. Reis-Filho, 2012. Low-estrogen receptor-positive breast cancer: The impact of tissue sampling, choice of antibody and molecular subtyping. J. Clin. Oncol., 30: 2929-2930.
  147. Rakha, E.A., 2012. The low nuclear grade neoplasia family. Diagn. Histopathol., 18: 124-132.
  148. Rakha, E., S.C. Wong, I. Soomro, Z. Chaudry and A. Sharma et al., 2012. Clinical outcome of atypical endometrial hyperplasia diagnosed on an endometrial biopsy: Institutional experience and review of literature. Am. J. Surg. Pathol., 36: 1683-1690.
    CrossRef  |  Direct Link  |  
  149. Mukherjee, A. and E.A. Rakha, 2012. Integrating breast cancer genetics into clinical practice. Women's Health, 8: 99-112.
    CrossRef  |  Direct Link  |  
  150. Lee, A.H., N.M.V. Salinas, Z. Hodi, E.A. Rakha and I.O. Ellis, 2012. The value of examination of multiple levels of mammary needle core biopsy specimens taken for investigation of lesions other than calcification. J. Clin. Pathol., 65: 1097-1099.
    CrossRef  |  Direct Link  |  
  151. Lee, A.H., E.A. Rakha, Z. Hodi and I.O. Ellis, 2012. Re‐audit of revised method for assessing the mitotic component of histological grade in needle core biopsies of invasive carcinoma of the breast. Histopathology, 60: 1166-1167.
    CrossRef  |  Direct Link  |  
  152. Khoshnaw, S.M., E.A. Rakha, T.M. Abdel-Fatah, C.C. Nolan and Z. Hodi et al., 2012. Loss of Dicer expression is associated with breast cancer progression and recurrence. Breast Cancer Res. Treat., 135: 403-413.
    CrossRef  |  Direct Link  |  
  153. Habashy, H.O., D.G. Powe, T.M. Abdel‐Fatah, J.M. Gee and R.I. Nicholson et al., 2012. A review of the biological and clinical characteristics of luminal‐like oestrogen receptor‐positive breast cancer. Histopathology, 60: 854-863.
    CrossRef  |  Direct Link  |  
  154. Curtis, C., S.P. Shah, S.F. Chin, G. Turashvili and O.M. Rueda et al., 2012. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature, 486: 346-352.
    CrossRef  |  Direct Link  |  
  155. Brouckaert, O., R. Paridaens, G. Floris, E. Rakha, K. Osborne and P. Neven, 2012. A critical review why assessment of steroid hormone receptors in breast cancer should be quantitative. Ann. Oncol., 24: 46-53.
    CrossRef  |  Direct Link  |  
  156. Alshareeda, A.T., E.A. Rakha, C.C. Nolan, I.O. Ellis and A.R. Green, 2012. Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer. Breast Cancer Res. Treat., 134: 519-529.
    CrossRef  |  Direct Link  |  
  157. Aleskandarany, M.A., O.H. Negm, E.A. Rakha, M.A. Ahmed and C.C. Nolan et al., 2012. TOMM34 expression in early invasive breast cancer: A biomarker associated with poor outcome. Breast Cancer Res. Treat., 136: 419-427.
    CrossRef  |  Direct Link  |  
  158. Aleskandarany, M.A., A.R. Green, A.A. Benhasouna, F.F. Barros and K. Neal et al., 2012. Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer. Breast Cancer Res., Vol. 14. 10.1186/bcr3084.
    CrossRef  |  Direct Link  |  
  159. Ahmed, M.A., M.A. Aleskandarany, E.A. Rakha, R.Z. Moustafa and A. Benhasouna et al., 2012. A CD44−/CD24+ phenotype is a poor prognostic marker in early invasive breast cancer. Breast Cancer Res. Treat., 133: 979-995.
    CrossRef  |  Direct Link  |  
  160. Agboola, A.J., E.C. Paish, E.A. Rakha, D.G. Powe, R.D. Macmillan, I.O. Ellis and A.R. Green, 2012. EpCAM expression is an indicator of recurrence in basal-like breast cancer. Breast Cancer Res. Treat., 133: 575-582.
    CrossRef  |  Direct Link  |  
  161. Agboola, A.J., A.A. Musa, N. Wanangwa, T. Abdel-Fatah and C.C. Nolan et al., 2012. Molecular characteristics and prognostic features of breast cancer in Nigerian compared with UK women. Breast Cancer Res. Treat., 135: 555-569.
    CrossRef  |  Direct Link  |  
  162. Van Deurzen, C.H., A.H. Lee, M.S. Gill, M.B. Menke-Pluijmers, A. Jager, I.O. Ellis and E.A. Rakha, 2011. Metaplastic breast carcinoma: tumour histogenesis or dedifferentiation? J. Pathol., 224: 434-437.
    CrossRef  |  Direct Link  |  
  163. Rakha, E.A., N. Gandhi, F. Climent, C.H. van Deurzen and S.A. Haider et al., 2011. Encapsulated papillary carcinoma of the breast: An invasive tumor with excellent prognosis. Am. J. Surg. Pathol., 35: 1093-1103.
    CrossRef  |  Direct Link  |  
  164. Rakha, E.A., B.C. Ho, V. Naik, S. Sen and L.J. Hamilton et al., 2011. Outcome of breast lesions diagnosed as lesion of uncertain malignant potential (B3) or suspicious of malignancy (B4) on needle core biopsy, including detailed review of epithelial atypia. Histopathology, 58: 626-632.
    CrossRef  |  Direct Link  |  
  165. Rakha, E.A., A.H. Lee, J.A. Jenkins, A.E. Murphy, L.J. Hamilton and I.O. Ellis, 2011. Characterization and outcome of breast needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening. Int. J. Cancer, 129: 1417-1424.
    CrossRef  |  Direct Link  |  
  166. Rakha, E.A. and S. Chan, 2011. Metastatic triple-negative breast cancer. Clin. Oncol., 23: 587-600.
  167. Rakha, E.A. and I.O. Ellis, 2011. Modern classification of breast cancer: Should we stick with morphology or convert to molecular profile characteristics. Adv. Anat. Pathol., 18: 255-267.
    CrossRef  |  Direct Link  |  
  168. O’Shea, A.M., E.A. Rakha, Z. Hodi, I.O. Ellis and A.H. Lee, 2011. Histological grade of invasive carcinoma of the breast assessed on needle core biopsy-modifications to mitotic count assessment to improve agreement with surgical specimens. Histopathology, 59: 543-548.
    CrossRef  |  Direct Link  |  
  169. Mohammed, R.A., I.O. Ellis, A.M. Mahmmod, E.C. Hawkes, A.R. Green, E.A. Rakha and S.G. Martin, 2011. Lymphatic and blood vessels in basal and triple-negative breast cancers: Characteristics and prognostic significance. Modern Pathol., 24: 774-785.
    CrossRef  |  Direct Link  |  
  170. Haider, A.S., E.A. Rakha, C. Dunkley and A.M. Zaitoun, 2011. The impact of using defined criteria for adequacy of fine needle aspiration cytology of the thyroid in routine practice. Diagn. Cytopathol., 39: 81-86.
    CrossRef  |  Direct Link  |  
  171. Habashy, H.O., E.A. Rakha, M. Aleskandarany, M.A. Ahmed, A.R. Green, I.O. Ellis and D.G. Powe, 2011. FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer. Breast Cancer Res. Treat., 129: 11-21.
    CrossRef  |  Direct Link  |  
  172. Habashy, H.O., D.G. Powe, E. Glaab, G. Ball and I. Spiteri et al., 2011. RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: A marker of ER-positive luminal-like subtype. Breast Cancer Res. Treat., 128: 315-326.
    CrossRef  |  Direct Link  |  
  173. Fernandez, B., E.C. Paish, A.R. Green, A.H. Lee, R.D. Macmillan, I.O. Ellis and E.A. Rakha, 2011. Lymph-node metastases in invasive lobular carcinoma are different from those in ductal carcinoma of the breast. J. Clin. Pathol., 64: 995-1000.
    CrossRef  |  Direct Link  |  
  174. Badve, S., D.J. Dabbs, S.J. Schnitt, F.L. Baehner and T. Decker et al., 2011. Basal-like and triple-negative breast cancers: A critical review with an emphasis on the implications for pathologists and oncologists. Modern Pathol., 24: 157-167.
    CrossRef  |  Direct Link  |  
  175. Aleskandarany, M.A., E.A. Rakha, R.D. Macmillan, D.G. Powe, I.O. Ellis and A.R. Green, 2011. MIB1/Ki-67 labelling index can classify grade 2 breast cancer into two clinically distinct subgroups. Breast Cancer Res. Treat., 127: 591-599.
    CrossRef  |  Direct Link  |  
  176. Aleskandarany, M.A., E.A. Rakha, M.A. Ahmed, D.G. Powe, I.O. Ellis and A.R. Green, 2011. Clinicopathologic and molecular significance of phospho-Akt expression in early invasive breast cancer. Breast Cancer Res. Treat., 127: 407-416.
    CrossRef  |  Direct Link  |  
  177. Zhang, H., E.A. Rakha, G.R. Ball, I. Spiteri and M. Aleskandarany et al., 2010. The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer. Breast Cancer Res. Treat., 121: 41-51.
    CrossRef  |  Direct Link  |  
  178. Soria, D., J.M. Garibaldi, F. Ambrogi, A.R. Green and D. Powe et al., 2010. A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients. Comput. Biol. Med., 40: 318-330.
    CrossRef  |  Direct Link  |  
  179. Rakha, E.A., V. Naik, Z. Chaudry, D. Baldwin and I.N. Soomro, 2010. Cytological assessment of conventional transbronchial fine needle aspiration of lymph nodes. Cytopathology, 21: 27-34.
    CrossRef  |  Direct Link  |  
  180. Rakha, E.A., S. Patil, K. Abdulla, M. Abdulkader, Z. Chaudry and I.N. Soomro, 2010. The sensitivity of cytologic evaluation of pleural fluid in the diagnosis of malignant mesothelioma. Diagn. Cytopathol., 38: 874-879.
  181. Rakha, E.A., L. Adamson, E. Bell, K. Neal, S.D. Ryder, P.V. Kaye and G.P. Aithal, 2010. Portal inflammation is associated with advanced histological changes in alcoholic and non-alcoholic fatty liver disease. J. Clin. Pathol., 63: 790-795.
    CrossRef  |  Direct Link  |  
  182. Rakha, E.A., J.S. Reis-Filho, F. Baehner, D.J. Dabbs and T. Decker et al., 2010. Breast cancer prognostic classification in the molecular era: The role of histological grade. Breast Cancer Res., Vol. 12. 10.1186/bcr2607.
    CrossRef  |  Direct Link  |  
  183. Rakha, E.A., J.S. Reis-Filho and I.O. Ellis, 2010. Combinatorial biomarker expression in breast cancer. Breast Cancer Res. Treatment, 120: 293-308.
    CrossRef  |  Direct Link  |  
  184. Rakha, E.A., A.H. Lee, J. Reed, A. Murphy and M. El-Sayed et al., 2010. Screen-detected malignant breast lesions diagnosed following benign (B2) or normal (B1) needle core biopsy diagnoses. Eur. J. Cancer, 46: 1835-1840.
    CrossRef  |  Direct Link  |  
  185. Rakha, E.A., A. Patel, D.G. Powe, A. Benhasouna and A.R. Green et al., 2010. Clinical and biological significance of E-cadherin protein expression in invasive lobular carcinoma of the breast. Am. J. Surg. Pathol., 34: 1472-1479.
    CrossRef  |  Direct Link  |  
  186. Rakha, E.A., A. Haider, S. Patil, H. Fourtan, Z. Chaudry and I.N. Soomro, 2010. Evaluation of touch preparation cytology during frozen-section diagnoses of pulmonary lesions. J. Clin. Pathol., 63: 675-677.
    CrossRef  |  Direct Link  |  
  187. Rakha, E.A. and I.O. Ellis, 2010. Lobular breast carcinoma and its variants. Semin. Diagn. Pathol., 27: 49-61.
    CrossRef  |  Direct Link  |  
  188. Mukherjee, A., M. Shehata, P. Moseley, E. Rakha, I. Ellis and S. Chan, 2010. Topo2α protein expression predicts response to anthracycline combination neo-adjuvant chemotherapy in locally advanced primary breast cancer. Br. J. Cancer, 103: 1794-1800.
    CrossRef  |  Direct Link  |  
  189. Marginean, F., E.A. Rakha, B.C. Ho, I.O. Ellis and A.H. Lee,. 2010. Histological features of medullary carcinoma and prognosis in triple-negative basal-like carcinomas of the breast. Modern Pathol., 23: 1357-1363.
    CrossRef  |  Direct Link  |  
  190. Lancashire, L.J., D.G. Powe, J.S. Reis-Filho, E. Rakha and C. Lemetre et al., 2010. A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks. Breast Cancer Res. Treat., 120: 83-93.
    CrossRef  |  Direct Link  |  
  191. Kwok, T.N.C., E.A. Rakha, A.H. Lee, M. Grainge, A.R. Green, I.O. Ellis and D.G. Powe, 2010. Histological grading of breast cancer on needle core biopsy: The role of immunohistochemical assessment of proliferation. Histopathology, 57: 212-219.
    CrossRef  |  Direct Link  |  
  192. Habashy, H.O., D.G. Powe, E.A. Rakha, G. Ball, R.D. Macmillan, A.R. Green and I.O. Ellis, 2010. The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype. Breast Cancer Res. Treat., 120: 603-612.
    CrossRef  |  Direct Link  |  
  193. Habashy, H.O., D.G. Powe, C.M. Staka, E.A. Rakha and G. Ball et al., 2010. Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast Cancer Res. Treat., 119: 283-293.
    CrossRef  |  Direct Link  |  
  194. Blows, F.M., K.E. Driver, M.K. Schmidt, A. Broeks and F.E. van Leeuwen et al., 2010. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: A collaborative analysis of data for 10,159 cases from 12 studies. PLoS Med., Vol. 7. 10.1371/journal.pmed.1000279.
    CrossRef  |  
  195. Aleskandarany, M.A., E.A. Rakha, M.A. Ahmed, D.G. Powe and E.C. Paish et al., 2010. PIK3CA expression in invasive breast cancer: A biomarker of poor prognosis. Breast Cancer Res. Treat., 122: 45-53.
    CrossRef  |  Direct Link  |  
  196. Aleskandarany, M.A., A.R. Green, E.A. Rakha, R.A. Mohammed and S.E. Elsheikh et al., 2010. Growth fraction as a predictor of response to chemotherapy in node‐negative breast cancer. Int. J. Cancer, 126: 1761-1769.
    CrossRef  |  Direct Link  |  
  197. Rakha, E.A., S.E. Elsheikh, M.A. Aleskandarany, H.O. Habashi and A.R. Green, 2009. Triple-negative breast cancer: Distinguishing between basal and nonbasal subtypes. Clin. Cancer Res., 15: 2302-2310.
    CrossRef  |  Direct Link  |  
  198. Rakha, E.A., M.S. Gill, M.E. El-Sayed, M.M. Khan and Z. Hodi et al., 2009. The biological and clinical characteristics of breast carcinoma with mixed ductal and lobular morphology. Breast Cancer Res. Treat., 114: 243-250.
    CrossRef  |  Direct Link  |  
  199. Rakha, E.A., M.E. El-Sayed, J. Reis-Filho and I.O. Ellis, 2009. Patho-biological aspects of basal-like breast cancer. Breast Cancer Res. Treat., 113: 411-422.
    CrossRef  |  Direct Link  |  
  200. Rakha, E.A., M.E. El-Sayed, J. Reed, A.H. Lee, A.J. Evans and I.O. Ellis, 2009. Screen-detected breast lesions with malignant needle core biopsy diagnoses and no malignancy identified in subsequent surgical excision specimens (potential false-positive diagnosis). Eur. J. Cancer, 45: 1162-1167.
    CrossRef  |  Direct Link  |  
  201. Rakha, E.A., M. Aleskandarany, M.E. El-Sayed, R.W. Blamey, C.W. Elston, I.O. Ellis and A.H.S. Lee, 2009. The prognostic significance of inflammation and medullary histological type in invasive carcinoma of the breast. Eur. J. Cancer, 45: 1780-1787.
    CrossRef  |  Direct Link  |  
  202. Rakha, E.A., A.H. Lee, A.J. Evans, S. Menon and N.Y. Assad et al., 2009. Tubular carcinoma of the breast: Further evidence to support its excellent prognosis. J. Clin. Oncol., 28: 99-104.
    CrossRef  |  Direct Link  |  
  203. Rakha, E.A. and I.O. Ellis, 2009. Triple-negative/basal-like breast cancer. Pathology, 41: 40-47.
    CrossRef  |  Direct Link  |  
  204. Rakha, E. and J.S. Reis-Filho, 2009. Basal-like breast carcinoma: From expression profiling to routine practice. Arch. Pathol. Lab. Med., 133: 860-868.
    Direct Link  |  
  205. Powe, D.G., G. Akhtar, H.O. Habashy, T. Abdel-Fatah, E.A. Rakha, A.R. Green and I.O. Ellis, 2009. Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification. Breast Cancer Res., Vol. 11. 10.1186/bcr2461.
    CrossRef  |  
  206. Paish, E.C., A.R. Green, E.A. Rakha, R.D. Macmillan, J.R. Maddison and I.O. Ellis, 2009. Three-dimensional reconstruction of sentinel lymph nodes with metastatic breast cancer indicates three distinct patterns of tumour growth. J. Clin. Pathol., 62: 617-623.
    CrossRef  |  Direct Link  |  
  207. Hamilton, L.J., A.J. Evans, E.J. Cornford, E.A. Rakha, I.O. Ellis and W.D. Foulkes, 2009. Will MRI screening deliver the expected survival advantage in BRCA 1 carriers? Clin. Radiol., 64: 1045-1047.
    CrossRef  |  Direct Link  |  
  208. Green, A.R., S. Krivinskas, P. Young, E.A. Rakha, E.C. Paish, D.G. Powe and I.O. Ellis, 2009. Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast. Breast Cancer Res. Treat., 113: 59-66.
    CrossRef  |  Direct Link  |  
  209. Green, A.R., P. Young, S. Krivinskas, E.A. Rakha, E.C. Paish, D.G. Powe and I.O. Ellis, 2009. The expression of ERα, ERβ and PR in lobular carcinoma in situ of the breast determined using laser microdissection and real‐time PCR. Histopathology, 54: 419-427.
    CrossRef  |  Direct Link  |  
  210. Foulkes, W.D., M.J. Grainge, E.A. Rakha, A.R. Green and I.O. Ellis, 2009. Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status. Breast Cancer Res. Treat., 117: 199-204.
    CrossRef  |  Direct Link  |  
  211. Elsheikh, S.E., A.R. Green, E.A. Rakha, D.G. Powe and R.A. Ahmed et al., 2009. Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors and patient outcome. Cancer Res., 69: 3802-3809.
    CrossRef  |  Direct Link  |  
  212. Doyle, S., A.J. Evans, E.A. Rakha, A.R. Green and I.O. Ellis, 2009. Influence of E-cadherin expression on the mammographic appearance of invasive nonlobular breast carcinoma detected at screening. Radiology, 253: 51-55.
    CrossRef  |  Direct Link  |  
  213. Au-Yong, I.T.H., A.J. Evans, S. Taneja, E.A. Rakha, A.R. Green, C. Paish and I.O. Ellis, 2009. Sonographic correlations with the new molecular classification of invasive breast cancer. Eur. Radiol., 19: 2342-2348.
    CrossRef  |  Direct Link  |  
  214. Tennant, S.L., A. Evans, L.J. Hamilton, J. James and A.H.S. Lee et al., 2008. Vacuum-assisted excision of breast lesions of uncertain malignant potential (B3)-an alternative to surgery in selected cases. Breast, 17: 546-549.
    CrossRef  |  Direct Link  |  
  215. Taneja, S., A.J. Evans, E.A. Rakha, A.R. Green, G. Ball and I.O. Ellis, 2008. The mammographic correlations of a new immunohistochemical classification of invasive breast cancer. Clin. Radiol., 63: 1228-1235.
    CrossRef  |  Direct Link  |  
  216. Rakha, E.A., V. Naik, J.S. Reis-Filho and I.O. Ellis, 2008. Outcome of basal-like breast cancer in routine practice. Am. J. Hematol. Oncol., 7: 432-436.
    Direct Link  |  
  217. Rakha, E.A., S.E. El-Sheikh, M.A. Kandil, M.E. El-Sayed, A.R. Green and I.O. Ellis, 2008. Expression of BRCA1 protein in breast cancer and its prognostic significance. Hum. Pathol., 39: 857-865.
    CrossRef  |  Direct Link  |  
  218. Rakha, E.A., M.E. El‐Sayed, J.S. Reis‐Filho and I.O. Ellis, 2008. Expression profiling technology: Its contribution to our understanding of breast cancer. Histopathology, 52: 67-81.
    CrossRef  |  Direct Link  |  
  219. Rakha, E.A., M.E. El-Sayed, S. Menon, A.R. Green, A.H. Lee and I.O. Ellis, 2008. Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast. Breast Cancer Res. Treat., 111: 121-127.
    CrossRef  |  Direct Link  |  
  220. Rakha, E.A., M.E. El-Sayed, D.G. Powe, A.R. Green and H. Habashy et al., 2008. Invasive lobular carcinoma of the breast: Response to hormonal therapy and outcomes. Eur. J. Cancer, 44: 73-83.
    CrossRef  |  Direct Link  |  
  221. Rakha, E.A., M.E. El-Sayed, A.H. Lee, C.W. Elston and M.J. Grainge et al., 2008. Prognostic significance of Nottingham histologic grade in invasive breast carcinoma. J. Clin. Oncol., 26: 3153-3158.
    CrossRef  |  Direct Link  |  
  222. Rakha, E.A., J.S. Reis-Filho and I.O. Ellis, 2008. Impact of basal-like breast carcinoma determination for a more specific therapy. Pathobiology, 75: 95-103.
    CrossRef  |  Direct Link  |  
  223. Rakha, E.A., J.S. Reis-Filho and I.O. Ellis, 2008. Basal-like breast cancer: A critical review. J. Clin. Oncol., 26: 2568-2581.
    Direct Link  |  
  224. Rakha, E.A., I.O. Ellis and J.S. Reis-Filho, 2008. Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). Mod. Pathol., 21: 1060-1061.
    CrossRef  |  Direct Link  |  
  225. Rakha, E., I. Ellis and J. Reis-Filho, 2008. Are triple-negative and basal-like breast cancer synonymous? Clin. Cancer Res., Vol. 14. 10.1158/1078-0432.CCR-07-1943.
    CrossRef  |  
  226. Luck, A.A., A.J. Evans, J.J. James, E.A. Rakha, E.C. Paish, A.R. Green and I.O. Ellis, 2008. Breast carcinoma with basal phenotype: Mammographic findings. Am. J. Roentgenol., 191: 346-351.
    CrossRef  |  Direct Link  |  
  227. Luck, A.A., A.J. Evans, A.R. Green, E.A. Rakha, C. Paish and I.O. Ellis, 2008. The influence of basal phenotype on the metastatic pattern of breast cancer. Clin. Oncol., 20: 40-45.
    CrossRef  |  Direct Link  |  
  228. Habashy, H.O., D.G. Powe, E.A. Rakha, G. Ball and C. Paish et al., 2008. Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance. Eur. J. Cancer, 44: 1541-1551.
    CrossRef  |  Direct Link  |  
  229. Green, A.R., C. Burney, C.J. Granger, E.C. Paish and S. El-Sheikh et al., 2008. The prognostic significance of steroid receptor co-regulators in breast cancer: Co-repressor NCOR2/SMRT is an independent indicator of poor outcome. Breast Cancer Res. Treat., 110: 427-437.
  230. El‐Sayed, M.E., E.A. Rakha, J. Reed, A.H.S. Lee, A.J. Evans and I.O. Ellis, 2008. Predictive value of needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening. Histopathology, 53: 650-657.
    CrossRef  |  Direct Link  |  
  231. Elsheikh, S.E., A.R. Green, E.A. Rakha, R.M. Samaka and A.A. Ammar et al., 2008. Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype. Br. J. Cancer, 99: 327-334.
    CrossRef  |  Direct Link  |  
  232. El-Sayed, M.E., E.A. Rakha, J. Reed, A.H. Lee, A.J. Evans and I.O. Ellis, 2008. Audit of performance of needle core biopsy diagnoses of screen detected breast lesions. Eur. J. Cancer, 44: 2580-2586.
    CrossRef  |  Direct Link  |  
  233. De Maeyer, L., E. van Limbergen, K. de Nys, P. Moerman and N. Pochet et al., 2008. Does estrogen receptor negative/progesterone receptor positive breast carcinoma exist? J. Clin. Oncol.: Official J. Am. Soc. Clin. Oncol., 26: 335-336.
    CrossRef  |  Direct Link  |  
  234. Rolland, P., I. Spendlove, Z. Madjid, E.A. Rakha, P. Patel, I.O. Ellis and L. Durrant, 2007. The p53 positive Bcl‐2 negative phenotype is an independent marker of prognosis in breast cancer. Int. J. Cancer, 120: 1311-1317.
    CrossRef  |  Direct Link  |  
  235. Rakha, E.A., M.E. El‐Sayed, A.R. Green, E.C. Paish, A.H.S. Lee and I.O. Ellis, 2007. Breast carcinoma with basal differentiation: A proposal for pathology definition based on basal cytokeratin expression. Histopathology, 50: 434-438.
    CrossRef  |  Direct Link  |  
  236. Rakha, E.A., M.E. El‐Sayed, A.R. Green, A.H. Lee, J.F. Robertson and I.O. Ellis, 2007. Prognostic markers in triple‐negative breast cancer. Cancer, 109: 25-32.
    CrossRef  |  Direct Link  |  
  237. Rakha, E.A., M.E. El-Sayed, A.R. Green, E.C. Paish and D.G. Powe et al., 2007. Biologic and clinical characteristics of breast cancer with single hormone receptor-positive phenotype. J. Clin. Oncol., 25: 4772-4778.
    CrossRef  |  Direct Link  |  
  238. Rakha, E.A., M.A. Kandil and M.G. El-Santawe, 2007. Gigantic recurrent abdominal desmoid tumour: A case report. Hernia, 11: 193-197.
    CrossRef  |  Direct Link  |  
  239. Rakha, E.A., D.S. Tan, W.D. Foulkes, I.O. Ellis, A. Tutt, T.O. Nielsen and J.S. Reis-Filho, 2007. Are triple-negative tumours and basal-like breast cancer synonymous? Breast Cancer Res., Vol. 9. 10.1186/bcr1827.
    CrossRef  |  
  240. Rakha, E.A. and I.O. Ellis, 2007. An overview of assessment of prognostic and predictive factors in breast cancer needle core biopsy specimens. J. Clin. Pathol., 60: 1300-1306.
    CrossRef  |  Direct Link  |  
  241. Evans, A.J., E.A. Rakha, S.E. Pinder, A.R. Green, C. Paish and I.O. Ellis, 2007. Basal phenotype: A powerful prognostic factor in small screen-detected invasive breast cancer with long-term follow-up. J. Med. Screening, 14: 210-214.
    CrossRef  |  Direct Link  |  
  242. Rakha, E.A., T.C. Putti, D.M. Abd El‐Rehim, C. Paish and A.R. Green et al., 2006. Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation. J. Pathol., 208: 495-506.
    CrossRef  |  Direct Link  |  
  243. Rakha, E.A., D.A. El-Rehim, C. Paish, A.R. Green and A.H. Lee et al., 2006. Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance. Eur. J. Cancer, 42: 3149-3156.
    CrossRef  |  Direct Link  |  
  244. Rakha, E.A., A.R. Green, D.G. Powe, R. Roylance and I.O. Ellis, 2006. Chromosome 16 tumor‐suppressor genes in breast cancer. Genes Chromosomes Cancer, 45: 527-535.
    CrossRef  |  Direct Link  |  
  245. Rakha, E., S. Ramaiah and A. McGregor, 2006. Accuracy of frozen section in the diagnosis of liver mass lesions. J. Clin. Pathol., 59: 352-354.
    CrossRef  |  Direct Link  |  
  246. Rakha, E., F. Puls, I. Saidul and P. Furness, 2006. Torsion of the testicular appendix: Importance of associated acute inflammation. J. Clin. Pathol., 59: 831-834.
    CrossRef  |  Direct Link  |  
  247. Abdulkader, M., K. Abdulla, E. Rakha and P. Kaye, 2006. Routine elastic staining assists detection of vascular invasion in colorectal cancer. Histopathology, 49: 487-492.
    CrossRef  |  Direct Link  |  
  248. Rakha, E.A., R.W. Boyce, D.A. El-Rehim, T. Kurien and A.R. Green et al., 2005. Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer. Mod. Pathol., 18: 1295-1304.
    CrossRef  |  Direct Link  |  
  249. Rakha, E.A., J.A. Armour, S.E. Pinder, C.E. Paish and I.O. Ellis, 2005. High‐resolution analysis of 16q22. 1 in breast carcinoma using DNA amplifiable probes (multiplex amplifiable probe hybridization technique) and immunohistochemistry. Int. J. Cancer, 114: 720-729.
    CrossRef  |  Direct Link  |  
  250. Rakha, E.A., D. Abd El Rehim, S.E. Pinder, S.A. Lewis and I.O. Ellis, 2005. E‐cadherin expression in invasive non‐lobular carcinoma of the breast and its prognostic significance. Histopathology, 46: 685-693.
    CrossRef  |  Direct Link  |  
  251. Rakha, E., C. Mayne and L. Brown, 2005. Mucinous metaplasia of the vulva in a case of lichen sclerosus. A case report. J. Clin. Pathol., 58: 1217-1218.
    CrossRef  |  Direct Link  |  
  252. Putti, T.C., D.M.A. El-Rehim, E.A. Rakha, C.E. Paish, A.H. Lee, S.E. Pinder and I.O. Ellis, 2005. Estrogen receptor-negative breast carcinomas: A review of morphology and immunophenotypical analysis. Mod. Pathol., 18: 26-35.
    CrossRef  |  Direct Link  |  
  253. Kurien, T., R.W.G. Boyce, E.C. Paish, J. Ronan and J. Maddison et al., 2005. Three dimensional reconstruction of a human breast carcinoma using routine laboratory equipment and immunohistochemistry. J. Clin. Pathol., 58: 968-972.
    CrossRef  |  Direct Link  |  
  254. Abd El‐Rehim, D.M., G. Ball, S.E. Pinder, E. Rakha and C. Paish et al., 2005. High‐throughput protein expression analysis using tissue microarray technology of a large well‐characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int. J. Cancer, 116: 340-350.
    CrossRef  |  Direct Link  |  
  255. Rakha, E.A., S.E. Pinder, E.C. Paish, J.F. Robertson and I.O. Ellis, 2004. Expression of E2F‐4 in invasive breast carcinomas is associated with poor prognosis. J. Pathol., 203: 754-761.
    CrossRef  |  Direct Link  |  
  256. Rakha, E.A., S.E. Pinder, C.E. Paish and I.O. Ellis, 2004. Expression of the transcription factor CTCF in invasive breast cancer: A candidate gene located at 16q22.1. Br. J. Cancer, 91: 1591-1596.
    CrossRef  |  Direct Link  |