Dr. Claire  Legay
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Dr. Claire Legay

Professor
Paris Descartes University, France


Highest Degree
Ph.D. in Molecular Medicine from University of the Mediterranean, France

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Area of Interest:

Biomedical Sciences
100%
Neuroscience
62%
Anatomy
90%
Embryology
75%
Medicine
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Legay, C., 2018. Congenital myasthenic syndromes with acetylcholinesterase deficiency, the pathophysiological mechanisms. Ann. N. Y. Acad. Sci., 1413: 104-110.
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  2. Messeant, J., J. Ezan, P. Delers, K. Glebov and C. Marchiol et al., 2017. Wnt proteins contribute to neuromuscular junction formation through distinct signaling pathways. Development, 144: 1712-1724.
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  3. Sigoillot, S.M., F. Bourgeois, J. Karmouch, J. Molgo and A. Dobbertin et al., 2016. Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency. FASEB J., 30: 2382-2399.
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  4. Messeant, J., A. Dobbertin, E. Girard, P. Delers and M. Manuel et al., 2015. MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance. J. Neurosci., 35: 4926-4941.
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  5. Bourgeois, F., J. Messeant, E. Kordeli, J.M. Petit and P. Delers et al., 2015. A critical and previously unsuspected role for doublecortin at the neuromuscular junction in mouse and human. Neuromuscular Disord., 25: 461-473.
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  6. Karmouch, J., A. Dobbertin, S. Sigoillot and C. Legay, 2013. Developmental consequences of the ColQ/MuSK interactions. Chemico-Biol. Interact., 203: 287-291.
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  7. Strochlic, L., J. Falk, E. Goillot, S. Sigoillot and F. Bourgeois et al., 2012. Wnt4 participates in the formation of vertebrate neuromuscular junction. PLoS ONE, Vol. 7. 10.1371/journal.pone.0029976.
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  8. Richard, A.F., J. Demignon, I. Sakakibara, J. Pujol and M. Favier et al., 2011. Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev. Biol., 359: 303-320.
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  9. Sigoillot, S.M., F. Bourgeois, M. Lambergeon, L. Strochlic and C. Legay, 2010. ColQ controls postsynaptic differentiation at the neuromuscular junction. J. Neurosci., 30: 13-23.
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  10. Sigoillot, S.M., F. Bourgeois and C. Legay, 2010. Cholinesterases regulation in the absence of ColQ. Chemico-Biol. Interact., 187: 84-89.
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  11. Guerra, M., A. Dobbertin and C. Legay, 2008. Identification of cis-acting elements involved in acetylcholinesterase RNA alternative splicing. Mol. Cell. Neurosci., 38: 1-14.
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