Dr. Afonne, Onyenmechi Johnson
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Dr. Afonne, Onyenmechi Johnson

Lecturer
Nnamdi Azikiwe University, Nigeria

Highest Degree
Ph.D. in Pharmacology from Nnamdi Azikiwe University, Awka, Nigeria

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Area of Interest:

Pharmacology and Toxicology
100%
Pharmacology
62%
Health Science
90%
Reproductive Toxicology
75%
Pharmaceutical Research
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Oluboyo, A.O., C.C. Onyenekwe, O.J. Afonne, B.O. Oluboyo, D.A. Orji and M. Nwankwo, 2010. Some biochemical parameters in pre and post menopausal women in Nnewi, Nigeria. Afr. J. Med. Sci., 3: 11-16.
  2. Afonne, O., O. Orisakwe and I. Onyiaorah, 2010. Reproductive effects of two crude oils in male guinea pig. Abstr. Toxicol. Lett., 196S: S185-S186.
    CrossRef  |  
  3. Oluboyo, A.O., O.J. Afonne, B.O. Oluboyo, A.C. Okeke, R.C. Chukwuanukwu and T.O. Chukwuanukwu, 2009. Pattern of lipid profiles in HIV seropositive subjects on antiretroviral therapy. J. Adv. Med. Pharmaceut. Sci., 3: 40-42.
  4. Orisakwe, O.E., E. Nwachukwu, H.B. Osadolor, O.J. Afonne and C.E. Okocha, 2007. Liver and kidney function tests amongst paint factory workers in Nkpor, Nigeria. Toxicol. Ind. Health, 23: 161-165.
    CrossRef  |  
  5. Chiroma, H.D., G.T. Ayinla, O.E. Orish, O.O. Emmanuel and A.A. Jigam et al., 2007. Seasonal nitrate content of stream water, soil and some Foodstuffs samples in Abuja municipal area of Federal Capital Territory,Nigeria. J. Health Sci., 53: 359-364.
    Direct Link  |  
  6. Orisakwe, O.E., I.O. Igwilo, J.O. Afonne, J.U. Maduabuchi and J.C. Nduka, 2006. Heavy metal hazards of sachet water in Nigeria. J. Arch. Environ. Occup. Health, 61: 209 -213.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Igwilo, I.O., J.O. Afonne, U.J. Maduabuchi and O.E. Orisakwe, 2006. Toxicological study of the Anam River in Otuocha, Anambra State, Nigeria. J. Arch. Environ. Occup. Health, 61: 205-208.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Orisakwe, O.E., D.D. Akumka, A.A. Njan, O.J. Afonne and O.O. Okechi, 2005. Hepatotoxic and haematologic effects of Nigerian bonny light crude oil in male albino rats. Toxicol. Environ. Chem., 87: 215-221.
    CrossRef  |  Direct Link  |  
  9. Asomugha, R., O.E. Orisakwe, O.J. Afonne, E. Obi, J.C. Nduka and C.E. Dioka, 2005. Impact of effluents from cable manufacturing plant on food, water and soil qualities in nnewi, Nigeria. Pak. J. Biol. Sci., 8: 744-747.
    CrossRef  |  Direct Link  |  
  10. Ugwoke, C.C., E.D. Nwobodo, P. Unekwe, S.T. Chukwuma, M.A.C. Odike and O.J. Afonne, 2004. Fuel vapour disrupts the histoarchitecture of reproductive organs in albino rats (Wistar). J. Sci. Indust. Stud., 2: 72-74.
  11. Orisakwe, O.E., R. Asomugha, O.J. Afonne, C.N. Anisi, E. Obi and C.E. Dioka, 2004. Impact of effluents from a car battery manufacturing plant in Nigeria on water, soil and food qualities. Arch Environ. Health, 59: 31-36.
    CrossRef  |  Direct Link  |  
  12. Orisakwe, O.E., D.D. Akumka, A.A. Njan and O.J. Afonne, 2004. Testicular toxicity of Nigerian bonny light crude oil in male albino rats. Reprod. Toxicol., 18: 439-442.
    PubMed  |  
  13. Orisakwe, O.E., D.C. Husaini and O.J. Afonne, 2004. Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats. Reprod. Toxicol., 18: 295-298.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Orisakwe, O.E., O.J. Afonne, M.A. Chude, E. Obi and C.E. Dioka, 2003. Sub-chronic toxicity studies of the aqueous extract of Boerhavia diffusa leaves. J. Health Sci., 49: 444-447.
    Direct Link  |  
  15. Ofoefule, S.I., C.E. Obodo, O.E. Orisakwe, O.J. Afonne and N.A. Ilondu et al., 2002. Salivary and urinary excretion and plasma-saliva concentration ratio of isoniazid (INH) in the presence of co-administered ciprofloxacin. Am. J. Ther., 9: 15-18.
    Direct Link  |  
  16. Dioka, C., O.E. Orisakwe, O.J. Afonne, P.U. Agbasi, D.D. Akumka, C.J. Okonkwo and N. Ilondu, 2002. Investigation into the haematologic and hepatic effects of rinbacin in rats. J. Health Sci., 48: 393-398.
    Direct Link  |  
  17. Afonne, O.J., O.E. Orisakwe, S.I. Ofoefule, S. Tsalha, E. Obi, N.A. Ilondu and O. Okorie, 2002. Saline cathartics and adsorptive capacity of activated charcoal for doxycycline. Acta Poloniae Pharmaceutica-Drug Res., 59: 177-179.
    PubMed  |  Direct Link  |  
  18. Afonne, O.J., O.E. Orisakwe, E. Obi, C.E. Dioka and G.I. Ndubuka, 2002. Nephrotoxic actions of low-dose mercury in mice: Protection by zinc. Arch. Environ. Health., 57: 98 -102.
    PubMed  |  
  19. Afonne, O.J., O.E. Orisakwe, C.E. Dioka, E. Obi, T. Ezejiofor, L. Asomugha and U. Ukoha, 2002. Effects of rinbacin on rat kidney. Biol. Pharm. Bull., 28: 1022-1025.
  20. Afonne, O.J., O.E. Orisakwa, O.A. Ekanem and D.D. Akumka, 2002. Zinc protects chromium-induced testicular injury in mice. Indian J. Pharmacol., 34: 26-31.
    Direct Link  |  
  21. Orisakwe, O.E., O.J. Afonne, E. Nwobodo, L. Asomugha and C.E. Dioka, 2001. Low-dose mercury induces testicular damage protected by zinc in mice. Eur. J. Obstet. Gynecol. Reprod. Biol., 95: 92-96.
    CrossRef  |  PubMed  |  
  22. Ofoefule, S.I., C.E. Obodo, O.E. Orisakwe, N.A. Ilondu and O.J. Afonne et al., 2001. Some plasma pharmacokinetic parameters of isoniazid (INH) in the presence of a fluoroquinolone antibacterial agent. Am. J. Ther., 8: 243-246.
    PubMed  |  
  23. Chude, M.A., O.E. Orisakwe, O.J. Afonne, K.S. Gamaniel, O.H. Vongtau and E. Obi, 2001. Hypoglycaemic effect of the aqueous extract of Boerhavia diffusa leaves. Indian J. Pharm., 33: 215-216.
    Direct Link  |  
  24. Agbasi, P.U., O.E. Orisakwe, E. Obi, S.I. Ofoefule, N.A. Ilondu and O.J. Afonne, 2001. Effect of sulphate cathartics on the adsorption of rifampicin to activated charcoal. Indian J. Pharmac. Sci., 63: 328-330.
    Direct Link  |  
  25. Orisakwe, O.E., N.A. Ilondu, O.J. Afonne, S.I. Ofoefule and C.N. Orish, 2000. Acceleration of body clearance of diethylcarbamazine by oral activated charcoal. Pharm. Res., 42: 167-170.
    PubMed  |  
  26. Orisakwe, O.E., K.C. Chilaka, O.J. Afonne, E. Obi and N. Ilondu, 2000. Evaluation of the developmental toxicity of amlodipine besylate in mice. J. Health Sci., 46: 42-45.
    Direct Link  |  
  27. Orisakwe, O.E., D.D. Akumka, O.J. Afonne and K.S. Gamaniel, 2000. Investigation into the pharmacological basis for some of the folkoric uses of bonny light crude oil in Nigeria. Indian J. Pharm., 32: 231-234.
    Direct Link  |  
  28. Obi, E., J.K. Emeh, O.E. Orisakwe, O.J. Afonne, N.A. Ilondu and P.U. Agbasi, 2000. Investigation of the biochemical evidence for the antiulcerogenic activities of Synclisia scabrida. Indian J. Phamcol., 32: 381-383.
    Direct Link  |  
  29. Ilondu, N., O.E. Orisakwe, S.I. Ofoefule, O.J. Afonne, E. Obi, K.C. Chilaka and C. Orish, 2000. Pharmacokinetics of diethylcarbamazine: Prediction by concentration in saliva. Biol. Pharm.. Bull., 23: 443-445.
    Direct Link  |  
  30. Afonne, O.J., O.E. Orisakwe, G.I. Ndubuka, D.D. Akumka and N. Ilondu, 2000. Zinc protection of mercury-induced hepatic toxicity in mice. Biol. Pharm. Bull., 23: 305-308.
    PubMed  |  
  31. Afonne, O.J., O.E. Orisakwe, E. Obi, C. Orish and D.D. Akumka, 2000. Some pharmacological properties of Synclisia scabrida III. Indian J. Pharmacol., 32: 239-241.
    Direct Link  |  
  32. Orisakwe, O.E., R. Asomugha, O.J. Afonne, E. Obi, K.C. Chilaka and C.E. Dioka, 1999. Effect of industrial effluents on water and soil qualities in Nnewi, Nigeria. J. Health Sci., 45: 177-183.
    Direct Link  |  
  33. Afonne, O.J. and O.E. Orisakwe, 1999. Cytokines in environmental toxicology Trop. J. Med. Res., 3: 1-8.
  34. Orisakwe, O.E., O.J. Afonne, C.F. Dioka and C.S. Ufearo, 1996. Investigation into the oestrogen-like activity of Synclisia scabrida. Fitoterapia, 67: 469-471.
    Direct Link  |  
  35. Orisakwe, O.E., O.J. Afonne, C.E. Dioka, C.S. Ufearo, A.N. Okpogba and S.I. Ofoefule, 1996. Some pharmacological properties of Synclisia scabrida II. Indian J. Med. Res., 103: 282-284.
    PubMed  |