Dr. Jonah Sydney Aprioku
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Dr. Jonah Sydney Aprioku

Associate Professor and HOD
University of Port Harcourt, Nigeria


Highest Degree
Ph.D. in Pharmacology from University of Port Harcourt, Nigeria

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Biography

Dr. Jonah S. Aprioku is presently working as Lecturer at Department of Experimental Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Port Harcourt, Nigeria. He has obtained his PhD in Pharmacology from same University. Previously he was served as Pharmacist-in-charge / Pharmacology Lecturer at National Youth Service Corpse (NYSC). He has 15 publications in journals contributed as author/co-author.

Area of Interest:

Pharmacology and Toxicology
100%
Reproductive Toxicology
62%
Environmental Toxicology
90%
Phytomedical Research
75%
Drug Interactions
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Udoh, I.E., J.S. Aprioku and I.M. Siminialayi, 2017. In-vivo anti-tumor evaluation of dihydroartemisinin-derived endodisulphide on MNU-induced liver cancer in sprague-dawley rats. Int. J. Trop. Dis. Health, Vol. 25. .
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  2. Onyagbodor, O.A. and J.S. Aprioku, 2017. Moringa oleifera leaf extract inhibits diabetogenic effect of alloxan in rats. IOSR J. Pharm., 7: 7-12.
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  3. Aprioku, J.S. and F.S. Amah-Tariah, 2017. Garlic (Allium sativum L) protects hepatic and renal toxicity of alloxan in rats. J. Pharmaceut. Res. Int., 17: 1-7.
  4. Aprioku, J.S. and A.C. Mankwe, 2017. Study on testicular response to prolong artemisinin‐based combination therapy treatments in guinea pigs. Andrologia. 10.1111/and.12852.
    CrossRef  |  Direct Link  |  
  5. Ugwu, T.C. and J.S. Aprioku, 2016. Nasal snuff (Nigeria local smokeless tobacco) administration raises hepatic enzyme plasma levels in Wistar rats. Eur. J. Med. Plants, 16: 1-7.
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  6. Udoh, I.E., J.S. Aprioku and I.M. Siminialayi, 2016. Acute and sub-acute toxicity evaluation of disulphide derivative of dihydroartemisinin. World J. Pharmaceut. Res., 6: 77-95.
  7. Mankwe, A.C., J.S. Aprioku and A.W. Obianime, 2016. Effects of artemisinin-based combination therapies on lipids and hepatorenal circulating indices in guinea pigs. Am. J. Pharmacol. Toxicol., 11: 26-31.
  8. Aprioku, J.S., O.S. Joseph and A.W. Obianime, 2016. Quantification of antinociceptive and antiinflammatory potentials of different Ocimum gratissimum Linn. Leaf extracts in male whistar albino rats. Eur. J. Med. Plants, 17: 1-8.
  9. Aprioku, J.S. and T.C. Ugwu, 2016. Tobacco smoke exposure induces irreversible alteration of testicular function in prepubertal rats. J. Basic Clin. Physiol. Pharmacol., 27: 577-584.
    CrossRef  |  
  10. Aprioku, J.S. and T.C. Ugwu, 2015. Comparative evaluation of the impact of subacute exposure of smokeless tobacco and tobacco smoke on rat testis. Int. J. Reprod. Med., Vol. 2015. 10.1155/2015/676245.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Nwidu, L.L., J.S. Aprioku and F.H. Guluye, 2014. Study on radical scavenging and gastroprotective effects of ethanolic stem-bark extract of carpolobia lutea in rodents. World J. Pharm. Res., 3: 73-88.
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  12. Aprioku, J.S., L.L. Nwidu and C.N. Amadi, 2014. Evaluation of toxicological profile of ibuprofen in Wistar albino rats. Am. J. Biomed. Sci., 6: 32-40.
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  13. Aprioku, J.S., C. Ibeachu and M.A. Ijeomah, 2014. Protective effect of ascorbic acid on cimetidine-induced reproductive toxicity in male wistar rats. J. Pharmacol. Toxicol., 9: 46-54.
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  14. Aprioku, J.S., C. Ibeachu and F.S. Amah-Tariah, 2014. Differential effects of H2 receptor antagonists on male reproductive function and hepatic enzymes in Wistar rats. Asian J. Biomed. Pharm. Sci., 4: 1-6.
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  15. Aprioku, J.S., B. Ebenezer and M.A. Ijomah, 2014. Toxicological effects of cadmium during pregnancy in Wistar albino rats. Toxicol. Environ. Health Sci., 6: 16-24.
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  16. Aprioku, J.S., 2014. Gestational outcome in rats: Aqueous Bryophyllum pinnatum leaf extracts vs. salbutamol administration. World J. Pharm. Res., 3: 29-37.
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  17. Aprioku, J.S. and A.W. Obianime, 2014. Evaluation of the effects of Citrus aurantifolia (lime) juice in lead-induced hematological and testicular toxicity in rats. Pharmacologia, 5: 36-41.
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  18. Obianime, A.W., N.J. Ahiwe and J.S. Aprioku, 2013. Effects of vitamins C and E pretreatments on cadmiuminduced serum levels of some biochemical and hormonal parameters in the female guinea pig. Afr. J. Biotechnol., 9: 6582-6587.
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  19. Aprioku, J.S., 2013. Testicular effects of artemisinins: Are they reversible? Res. J. Pharm. Biol. Chem. Sci., 4: 1152-1160.
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  20. Aprioku, J.S., 2013. Pharmacology of free radicals and the impact of reactive oxygen species on the testis. J. Reprod. Infertil., 14: 158-172.
    PubMed  |  Direct Link  |  
  21. Aprioku, J.S. and I.M. Siminialayi, 2013. Maternal lead exposure and pregnancy outcome in Wistar albino rats. J. Toxicol. Environ. Health Sci., 5: 185-193.
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  22. Aprioku, J.S. and F.I. Uche, 2013. Renal effects of non-steroidal anti-inflammatory drugs in albino rats. Br. J. Pharmaceut. Res., 3: 314-325.
  23. Aprioku, J.S., 2012. Current trends in malaria and tuberculosis chemotherapy. Adv. Environ. Biol., 6: 534-542.
  24. Aprioku, J.S. and A.W. Obianime, 2012. Evaluation of biochemical indices following administration of artemether, halofantrine and a combination of artemether and lumefantrine in guinea pigs. J. Applied Pharmaceut. Sci., 2: 54-59.
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  25. Obianime, A.W., J.S. Aprioku and N.J. Ahiwe, 2011. Biochemical and hormonal effects of cadmium in female guinea pigs. J. Toxicol. Environ. Health Sci., 3: 39-43.
  26. Obianime, A.W., J.S. Aprioku and C. Esomonu, 2011. The effects of aqueous Ocimum gratissimum leaf extract on some biochemical and hematological parameters in male mice. Asian J. Biol. Sci., 4: 44-52.
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  27. Obianime, A.W. and J.S. Aprioku, 2011. Mechanism of action of artemisinins on biochemical, hematological and reproductive parameters in male guinea pigs. Int. J. Pharmacol., 7: 84-95.
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  28. Aprioku, J.S. and A.W. Obianime, 2011. Structure-Activity-Relationship (SAR) of artemisinins on some biological systems in male guinea pigs. Insight Pharm. Sci., 1: 1-10.
    CrossRef  |  
  29. Uche, F.I., A.W. Obianime and J.S. Aprioku, 2010. The comparative effects of aqueous extract of Tetracarpidium conophorum seeds and proviron on the sperm parameters of male guinea pigs. Niger. J. Pharmaceut. Res., 8: 229-235.
  30. Obianime, A.W., J.S. Aprioku and C.T. Esomonu, 2010. Antifertility effects of aqueous crude extract of Ocimum gratissimum L. leaves in male mice. J. Med. Plants Res., 4: 809-816.
  31. Obianime, A.W. and J.S. Aprioku, 2010. The effects of dihydroartemisinin on biochemical, hormonal and reproductive parameters of male guinea-pigs. J. Pharm. Pharmacol. Res., 1: 1-8.
  32. Obianime, A.W. and J.S. Aprioku, 2009. Comparative testicular histopathological effects of artemisinin derivatives and some ACTS in the guinea-pig. J. Exp. Clin. Anatomy, 8: 31-40.
  33. Obianime, A.W. and J.S. Aprioku, 2009. Comparative study of artesunate, ACTs and their combinants on the spermatic parameters of the male guinea pig. Niger. J. Physiol. Sci., 24: 1-6.
    PubMed  |  Direct Link  |  
  34. Obianime, A.W. and J.S. Aprioku, 2009. Comparative study of artesunate, ACTs and their combinants on the hormonal parameters of the male guinea-pig. Niger. J. Physiol. Sci., 24: 95-100.
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  35. Aprioku, J.S., A.W. Obianime and B.C. Didia, 2009. Ocinum gratissimum Linn., cadmium and testicular structure of the male guinea-pig. J. Exp. Clin. Anat., 8: 8-12.
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  36. Aprioku, J.S., A.W. Obianime and B.C. Didia, 2009. Ocimum gratissimum Linn. reverses cadmium-induced toxicity of spermatic parameters of the male guinea-pig. J. Expt. Clin. Anal., 8: 1-7.
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  37. Aprioku, J.S. and A.W. Obianime, 2009. Effects of the aqueous leaf extract of Ocimum gratissimum Linn. (Lamiaceae) on some cadmium-induced biochemical changes in male guinea-pigs. West Afr. J. Pharmacol. Drug Res., 24: 41-47.
  38. Uche, F.I. and J.S. Aprioku, 2008. The phytochemical constituents, analgesic and anti-inflammatory effects of methanol extract of Jatropha curcas sp leaves in mice and Wister albino rats. J. Applied Sci. Environ. Manage., 12: 99-102.
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  39. Aprioku, J.S. and A.W. Obianime, 2008. Antioxidant activity of the aqueous crude extract of Ocimum gratissimum Linn. leaf on basal and cadmium-induced serum levels of phosphatases in male guinea-pigs. JASEM., 12: 33-39.
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  40. Aprioku, J. and A. Obianime, 2008. Comparative and interactive studies of aqueous leaf extracts of Ocimum gratissimum Linn.(lamiaeceae), vitamins C and E on the basal serum phosphatase levels of male Guinea pigs. West Afr. J. Pharmacol. Drug Res., 24: 48-55.
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