Dr. Mohammed Aziz
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Dr. Mohammed Aziz

Professor
Mohammed the First University, Morocco

Highest Degree
Ph.D. in Zoology Science from Free University Brussels, Belgium

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Area of Interest:

Animal and Veterinary Sciences
100%
Zoological Research
62%
Cell Biology
90%
Animal Biology
75%
Animal Physiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Hakkou, Z., A. Maciuk, V. Leblais, N.E. Bouanani and H. Mekhfi et al., 2017. Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive. Biomed. Pharmacother., 93: 62-69.
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  2. Dib, I., M. Tits, L. Angenot, J.N. Wauters and A. Assaidi et al., 2017. Antihypertensive and vasorelaxant effects of aqueous extract of Artemisia campestris L. from Eastern Morocco. J. Ethnopharmacol., 206: 224-235.
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  3. Dib, I., A. Mihamou, M. Berrabah, H. Mekhfi and M. Aziz et al., 2017. Identification of Artemisia campestris L. subsp. glutinosa (Besser) Batt. from oriental Morocco based on its morphological traits and essential oil profile. J. Mater. Environ. Sci., 8: 180-187.
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  4. Dib, I., Marie-Laure Fauconnier, M. Sindic, F. Belmekki and A. Assaidi et al., 2017. Chemical composition, vasorelaxant, antioxidant and antiplatelet effects of essential oil of Artemisia campestris L. from Oriental Morocco. BMC Comp. Altern. Med., Vol. 17. 10.1186/s12906-017-1598-2.
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  5. Bendaif, H., A. Melhaoui, M. El Azzouzi, B. Legssyer and T. Hamat et al., 2016. Eco-friendly Pancratium foetidum Pom extracts as corrosion inhibitors for mild steel in 1M HCl media. J. Mater. Environ. Sci., 7: 1276-1287.
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  6. Beyi, L., M. Aziz, H. Makrane, A. Karim, M. Bnouham and A. Ziyyat, 2015. Antidiarrheal activity of Thymus algeriensis Boiss and Reut aqueous extract on rats and mice. Int. J. Pharm. Pharmaceut. Sci., 7: 292-294.
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  7. Beyi, L., M. Aziz, H. Makrane, A. Karim and C. Alem et al., 2015. Anti-diarrheal effect of Cotula cinerea Del. aqueous extract on rats and mice. Res. J. Pharmaceut. Biol. Chem. Sci., 6: 219-224.
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  8. Berraaouan, A., Z. Abderrahim, M. Hassane, L. Abdelkhaleq, A. Mohammed and B. Mohamed, 2015. Evaluation of protective effect of cactus pear seed oil (Opuntia ficus-indica L. Mill.) against alloxan-induced diabetes in mice. Asian Pac. J. Trop. Med., 8: 532-537.
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  9. Aziz, M., K. Oubenchiker, A. Karim, H. Mekhfi and M. Bnouham, 2015. Evaluation of the antidiarrheal activity of the aqueous extract of Cistus salviifolius L. aerial parts. Mintage J. Pharmaceut. Med. Sci., 4: 11-13.
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  10. Ahmed, K., H. Zrouri, S. Amrani, M. Bnouham, A. Ziyyat, S. Amrani and M. Aziz, 2015. Antimotolity effect of organic extracts of Anthemis mauritiana Maire & Sennen flowers on the rodent isolated jejunum. Asian J. Pharmaceut. Clin. Res., 8: 154-158.
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  11. Afkir, S., M. Markaoui, M. Aziz, M. Bnouham, H. Mekhfi, A. Legssyer and A. Ziyyat, 2015. Effect of flavonoids from Arbutus unedo leaves on rat isolated thoracic aorta. Arabian J. Med. Arom. Plants, 1: 75-93.
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  12. Ziyyat, A., N. Ramdani, N.E.H. Bouanani, J. Vanderpas and B. Hassani et al., 2014. Epidemiology of hypertension and its relationship with type 2 diabetes and obesity in Eastern Morocco. SpringerPlus, Vol. 3. 10.1186/2193-1801-3-644.
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  13. Tits, M., L. Angenot, J.N. Wauters, M. Frederich and I. Dib et al., 2014. Phytochemical analysis of Tetraclinis articula in relation to its vasorelaxant property. J. Mater. Environ. Sci., 5: 1368-1375.
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  14. Oubenchiker, K., A. Karim, H. Mekhfi, A. Legssyer, A. Ziyyat, A. Melhaoui and M. Aziz, 2014. Inhibitory effects of Cistus salvifolius on contractile responses in the isolated rabbit and rat jejunum. Res. J. Pharmaceut. Biol. Chem. Sci., 5: 1450-1456.
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  15. Berraaouan, A., A. Ziyyat, H. Mekhfi, A. Legssyer, M. Sindic, M. Aziz and M. Bnouham, 2014. Evaluation of antidiabetic properties of cactus pear seed oil in rats. Pharmaceut. Biol., 52: 1286-1290.
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  16. Aziz, M., A. Karim, N. Tab, M. Berrabah, H. Mekhfi and A. Melhaoui, 2014. Antispasmodic effect of essential oil of Cistus ladaniferus on isolated rodent jejunums. Asian J. Phytomed. Clin. Res., 2: 196-203.
  17. Assaidi, A., A. Legssyer, A. Berrichi, M. Aziz, H. Mekhfi, M. Bnouham and A. Ziyyat, 2014. Hypotensive property of Chenopodium ambrosioides in anesthetized normotensive rats. J. Complement. Integr. Med., 11: 1-7.
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  18. Abid, S., A. Lekchiri, H. Mekhfi, A. Ziyyat, A. Legssyer, M. Aziz and M. Bnouham, 2014. Inhibition of α-glucosidase and glucose intestinal absorption by Thymelaea hirsuta fractions. J. Diabetes, 6: 351-359.
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  19. Harnafi, H., M. Ramchoun, M. Tits, J.N. Wauters and M. Frederich et al., 2013. Phenolic acid-rich extract of sweet basil restores cholesterol and triglycerides metabolism in high fat diet-fed mice: A comparison with fenofibrate. Biomed. Prev. Nutr., 3: 393-397.
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  20. Bellahcen, S., Z. Hakkou, A. Ziyyat, A. Legssyer, H. Mekhfi, M. Aziz and M. Bnouham, 2013. Antidiabetic and antihypertensive effect of virgin argan oil in model of neonatal streptozotocin-induced diabetic and L-Nitroarginine Methylester (L-NAME) hypertensive rats. J. Complement. Integr. Med., 10: 29-36.
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  21. Ramdani, N., J. Vanderpas, A. Boutayeb, A. Meziane and B. Hassani et al., 2012. Diabetes and obesity in the Eastern Morocco. Mediterr. J. Nutr. Metab., 5: 149-155.
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  22. Mekhfi, H., F. Belmekki, A. Ziyyat, A. Legssyer, M. Bnouham and M. Aziz, 2012. Antithrombotic activity of argan oil: An in vivo experimental study. Nutrition, 28: 937-941.
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  23. Himri, I., F. Souna, M. Aziz, A. Hakkou and E. Saalaoui, 2012. DNA damage induced by tartrazine in rat whole blood using comet assay (single cell gel electrophoresis). Adv. Environ. Biol., 6: 2875-2882.
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  24. Gadi, D., M. Bnouham, M. Aziz, A. Ziyyat and A. Legssyer et al., 2012. Flavonoids purified from parsley inhibit human blood platelet aggregation and adhesion to collagen under flow. J. Complement. Integr. Med., Vol. 9, No. 1. 10.1515/1553-3840.1579.
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  25. Bnouham, M., W. Benalla, S. Bellahcen, Z. Hakkou and A. Ziyyat et al., 2012. Antidiabetic and antihypertensive effect of a polyphenol-rich fraction of Thymelaea hirsuta L. in a model of neonatal streptozotocin-diabetic and NG-nitro-L-arginine methyl ester-hypertensive rats. J. Diabetes, 4: 307-313.
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  26. Bellahcen, S., H. Mekhfi, A. Ziyyat, A. Legssyer, A. Hakkou, M. Aziz and M. Bnouham, 2012. Prevention of chemically induced diabetes mellitus in experimental animals by virgin argan oil. Phytother. Res., 26: 180-185.
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  27. Aziz, M., A. Karim, H. Mekhfi, M. Bnouham, A. Ziyyat, A. Legssyer and A. Melhaoui, 2012. Antispasmodic effects of aqueous extract of Anthemis mauritiana Maire & Sennen flowers. J. Applied Pharmaceut. Sci., 2: 41-44.
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  28. Aziz, M., A. Karim, E.M. El Ouariachi, A. Bouyanzer and S. Amrani et al., 2012. Relaxant effect of essential oil of Artemisia herba-alba Asso. on rodent jejunum contractions. Sci. Pharmaceut., 80: 457-468.
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  29. Karim, A., J.P. Wathelet, H. Harnafi, S. Amrani, A. Melhaoui, M. El-Achouri and M. Aziz, 2011. Volatile components and antioxidant effect of essential oil of Anthemis mauritiana Maire & Sennen flowers. Oriental J. Chem., 27: 41-48.
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  30. Himri, I., S. Bellahcen, F. Souna, F. Belmakki and M. Aziz et al., 2011. A 90 day oral toxicity study of tartrazine, a synthetic food dye, in Wistar rats. Int. J. Pharm. Pharmaceut. Sci., 3: 159-169.
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  31. Aziz, M., A. Karim, N. Tab, H. Mekhfi and M. Bnouham et al., 2011. Antidiarrhoeal activity of Cistus ladaniferus aqueous extract. Spatula DD, 1: 175-179.
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  32. Skiker, M., H. Mekhfi, M. Aziz, B. Haloui and S. Lahlou et al., 2010. Artemisia herba-alba Asso relaxes the rat aorta through activation of NO/cGMP pathway and KATP channels. J. Smooth Muscle Res., 46: 165-174.
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  33. Karim, A., M. Berrabah, H. Mekhfi, A. Ziyyat and A. Legssyer et al., 2010. Effect of essential oil of Anthemis mauritiana Maire & Sennen flowers on intestinal smooth muscle contractility. J. Smooth Muscle Res., 46: 65-75.
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  34. Karim, A., H. Mekhfi, A. Ziyyat, A. Legssyer and M. Bnouham et al., 2010. Anti-diarrhoeal activity of crude aqueous extract of Rubia tinctorum L. roots in rodents. J. Smooth Muscle Res., 46: 119-123.
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  35. Bnouham, M., F.Z. Merhfour, A. Ziyyat, M. Aziz, A. Legssyer and H. Mekhfi, 2010. Antidiabetic effect of some medicinal plants of Oriental Morocco in neonatal non-insulin-dependent diabetes mellitus rats. Hum. Exp. Toxicol., 29: 865-871.
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  36. Harnafi, H., M. Aziz and S. Amrani, 2009. Sweet basil (Ocimum basilicum L.) improves lipid metabolism in hypercholesterolemic rats. Eur. e-J. Clin. Nutr. Metab., 4: e181-e186.
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  37. Gadi, D., M. Bnouham, M. Aziz, A. Ziyyat and A. Legssyer et al., 2009. Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats. J. Ethnopharmacol., 125: 170-174.
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  38. Benamar, M., A. Melhaoui, A. Zyad, I. Bouabdallah and M. Aziz, 2009. Anti-cancer effect of two alkaloids: 2R and 2S-bgugaine on mastocytoma P815 and carcinoma Hep. Nat. Prod. Res., 23: 659-664.
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  39. Belmokhtar, M., N.E. Bouanani, A. Ziyyat, H. Mekhfi and M. Bnouham et al., 2009. Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus. Biochem. Biophys. Res. Commun., 389: 145-149.
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  40. Atmani, F., C. Sadki, M. Aziz, M. Mimouni and B. Hacht, 2009. Cynodon dactylon extract as a preventive and curative agent in experimentally induced nephrolithiasis. Urol. Res., 37: 75-82.
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  41. Amrani, S., H. Harnafi, D. Gadi, H. Mekhfi and A. Legssyer et al., 2009. Vasorelaxant and anti-platelet aggregation effects of aqueous Ocimum basilicum extract. J. Ethnopharmacol., 125: 157-162.
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  42. Mekhfi, H., D. Gadi, M. Bnouham, A. Ziyyat, A. Legssyer and M. Aziz, 2008. Effect of argan oil on platelet aggregation and bleeding time: A beneficial nutritional property. J. Complement. Integr. Med., Vol. 5, No. 1. 10.2202/1553-3840.1164.
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  43. Harnafi, H., H.S. Caid, N.E.H. Bouanani, M. Aziz and S. Amrani, 2008. Hypolipemic activity of polyphenol-rich extracts from Ocimum basilicum in Triton WR-1339-induced hyperlipidemic mice. Food Chem., 108: 205-212.
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  44. Bravo, E., S. Amrani, M. Aziz, H. Harnafi and M. Napolitano, 2008. Ocimum basilicum ethanolic extract decreases cholesterol synthesis and lipid accumulation in human macrophages. Fitoterapia, 79: 515-523.
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  45. Afkir, S., T.B. Nguelefack, M. Aziz, J. Zoheir and G. Cuisinaud et al., 2008. Arbutus unedo prevents cardiovascular and morphological alterations in L-NAME-induced hypertensive rats: Part I: Cardiovascular and renal hemodynamic effects of Arbutus unedo in L-NAME-induced hypertensive rats. J. Ethnopharmacol., 116: 288-295.
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  46. Harnafi, H., N. El-Houda-Bouanani, M. Aziz, H.S. Caid, N. Ghalim and S. Amrani, 2007. The hypolipidaemic activity of aqueous Erica multiflora flowers extract in Triton WR-1339 induced hyperlipidaemic rats: A comparison with fenofibrate. J. Ethnopharmacol., 109: 156-160.
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  47. Mekhfi, H., M. ElHaouari, M. Bnouham, M. Aziz, A. Ziyyat and A. Legssyer, 2006. Effects of extracts and tannins from Arbutus unedo leaves on rat platelet aggregation. Phytother. Res., 20: 135-139.
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  48. El Haouari, M., M. Bnouham, M. Bendahou, M. Aziz, A. Ziyyat, A. Legssyer and H. Mekhfi, 2006. Inhibition of rat platelet aggregation by urtica dioica leaves extracts. Phytother. Res., 20: 568-572.
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  49. Aziz, M., N. Tab, A. Karim, H. Mekhfi and M. Bnouham et al., 2006. Relaxant effect of aqueous extract of Cistus ladaniferus on rodent intestinal contractions. Fitoterapia, 77: 425-428.
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  50. Amrani, S., H. Harnafi, N.H. Bouanani, M. Aziz and H.S. Caid et al., 2006. Hypolipidaemic activity of aqueous Ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property. Phytother. Res., 20: 1040-1045.
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  51. Lamkadem, M., I. Schwob, J. Mimouni, M. Aziz and A. Bouali et al., 2005. Cytotoxic effect and electrophysiological activity of S-irniine, a synthesised isomer of the natural R-irniine, on human MRC-5 fibroblasts. Nat. Prod. Res., 19: 573-580.
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  52. Mekhfi, H., M. El Haouari, A. Legssyer, M. Bnouham and M. Aziz et al., 2004. Platelet anti-aggregant property of some Moroccan medicinal plants. J. Ethnopharmacol., 94: 317-322.
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  53. Lamkadem, M., M. Aziz, I. Schwob, J. Rabier, J. Mimouni, R. Fontonge and A. Melhaoui, 2004. Cytotoxic effect and electrophysiological study on human MRC-5 fibroblasts of R-irniine, a natural alkylpyrrolidine alkaloid. Nat. Prod. Res., 18: 311-318.
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  54. Atmani, F., Y. Slimani, M. Mimouni, M. Aziz, B. Hacht and A. Ziyyat, 2004. Effect of aqueous extract from Herniaria hirsuta L. on experimentally nephrolithiasic rats. J. Ethnopharmacol., 95: 87-93.
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  55. Bnouham, M., F.Z. Merhfour, A. Ziyat, H. Mekhfi, M. Aziz and A. Legssyer, 2003. Antihyperglycemic activity of the aqueous extract of Urtica dioica. Fitoterpia, 74: 677-681.
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  56. Tahri, A., S. Yamani, A. Legssyer, M. Aziz, H. Mekhfi, M. Bnouham and A. Ziyyat, 2000. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J. Ethnopharmacol., 73: 95-100.
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  57. Aziz, M. and H. Alexandre, 1991. The origin of the nascent blastocoele in preimplantation mouse embryos ultrastructural cytochemistry and effect of chloroquine. Roux's Arch. Dev. Biol., 200: 77-85.
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  58. Treilhou-Lahille, F., A. Jullienne, M. Aziz, A. Beaumont and M.S. Moukhtar, 1984. Ultrastructural localization of immunoreactive calcitonin in the two cell types of the ultimobranchial gland of the common toad (Bufo bufo L.). Gen. Comp. Endocrinol., 53: 241-251.
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