Dr. H. P. Vasantha Rupasinghe
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Dr. H. P. Vasantha Rupasinghe

Associate Professor
Dalhousie University, Canada

Highest Degree
Ph.D. in Biotechnology from University of Guelph, Canada

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Area of Interest:

Plant and Soil Sciences
100%
Postharvest Biochemistry
62%
Physiology
90%
Molecular Biology
75%
Horticultural Sciences
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Jiang, Y., L. Zhang and H.V. Rupasinghe, 2017. Antiproliferative effects of extracts from Salvia officinalis L. and Saliva miltiorrhiza Bunge on hepatocellular carcinoma cells. Biomed. Pharmacother., 85: 57-67.
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  2. George, V.C., G. Dellaire and H.V. Rupasinghe, 2017. Plant flavonoids in cancer chemoprevention: Role in genome stability. J. Nutr. Biochem., 45: 1-14.
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  3. George, V.C. and H.P. Rupasinghe, 2017. Apple flavonoids suppress carcinogen-induced DNA damage in normal human bronchial epithelial cells. Oxidative Med. Cell. Longevity. 10.1155/2017/1767198.
    CrossRef  |  
  4. Ziaullah and H.P.V. Rupasinghe, 2016. Sonochemical enzyme-catalyzed regioselective acylation of flavonoid glycosides. Bioorg. Chem., 65: 17-25.
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  5. Warnakulasuriya, S.N., Ziaullah and H.P.V. Rupasinghe, 2016. Novel long chain fatty acid derivatives of quercetin-3-O-glucoside reduce cytotoxicity induced by cigarette smoke toxicants in human fetal lung fibroblasts. Eur. J. Pharmacol., 781: 128-138.
    CrossRef  |  Direct Link  |  
  6. Warnakulasuriya, S.N., Ziaullah and H.P.V. Rupasinghe, 2016. Long chain fatty acid esters of quercetin-3-O-glucoside attenuate H2O2-induced acute cytotoxicity in human lung fibroblasts and primary hepatocytes. Molecules, 21: 452-471.
    CrossRef  |  
  7. Rupasinghe, H.V., S. Sekhon-Loodu, T. Mantso and M.I. Panayiotidis, 2016. Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss. Pharmacol. Therapeut., 165: 153-163.
    CrossRef  |  
  8. Jiang, Y.Y., L. Zhang and H.P.V. Rupasinghe, 2016. The anticancer properties of phytochemical extracts from Salvia plants. Botanics: Targets Therapy, 1: 25-44.
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  9. George, V.C., V.V. Vijesh, D.I.M. Amarararathna and H.P.V. Rupasinghe, 2016. Mechanism of action of flavonoids in prevention of inflammation-associated skin cancer. Curr. Med. Chem., 23: 1-20.
  10. Fernando, W., M.R.P. Coombs, D.W. Hoskin and H.P.V. Rupasinghe, 2016. Docosahexaenoic acid-acylated phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells. Carcinogenesis, 37: 1004-1013.
    CrossRef  |  
  11. Bhullar, K.S. and H.P.V. Rupasinghe, 2016. Partridgeberry polyphenols protect primary cortical from oxygen-glucose deprivation-reperfusion induced injury via suppression of inflammatory adipokines and regulation of HIF-1α and PPARγ. Nutr. Neurosci., 19: 260-268.
  12. Amararathna, M., M.R. Johnston and H.P. Rupasinghe, 2016. Plant polyphenols as chemopreventive agents for lung cancer. Int. J. Molecular Sci., 17: 1352-1366.
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  13. Abachi, S., S. Lee and H.P.V. Rupasinghe, 2016. Molecular mechanisms of inhibition of Streptococcus species by phytochemicals. Molecules, 21: 215-246.
    CrossRef  |  
  14. Sudan, S. and H.P.V. Rupasinghe, 2015. Antiproliferative activity of long chain acylated esters of quercetin-3-O-glucoside in hepatocellular carcinoma HepG2 cells. Exp. Biol. Med., 240: 1452-1464.
    CrossRef  |  
  15. Sekhon-Loodu, S., Z. Ziaullah, H.V. Rupasinghe, Y. Wang, M. Kulka and F. Shahidi, 2015. Novel quercetin-3-O-glucoside eicosapentaenoic acid ester ameliorates inflammation and hyperlipidemia. Inflammopharmacology, 23: 173-185.
    CrossRef  |  
  16. Sekhon-Loodu, S. and H.P.V. Rupasinghe, 2015. Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages. Int. Immunopharmacol., 25: 199-206.
    CrossRef  |  
  17. Samadi, A.K., A. Bilsland, A.G. Georgakilas, A. Amedei and A. Amin et al., 2015. A multi-targeted approach to suppress tumor-promoting inflammation. Seminars Cancer Biol., 35: S151-S184.
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  18. Rupasinghe, H.P.V., M.A. Boehm, S. Sekhon-Loodu, I. Parmar, B. Bors and A.R. Jamieson, 2015. Anti-inflammatory activity of haskap (Lonicera caerulea L.) cultivars is dependent on their polyphenol content. Biomolecules, 5: 1079-1098.
  19. Potter, E., M. Jha, K.S. Bhullar, H.V. Rupasinghe, J. Balzarini and A. Jha, 2015. Investigation of fatty acid conjugates of 3, 5-bisarylmethylene-4-piperidone derivatives as antitumor agents and human topoisomerase-IIα inhibitors. Bioorg. Med. Chem., 23: 411-421.
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  20. Nileeka Balasuriya, H.P. Vasantha Rupasinghe, Marva Sweeney, Shelby McCarron, Katherine Gottschall-Pass 2015. Antihypertensive Effects of Apple Peel Extract on Spontaneously Hypertensive Rats Pharmacologia, 6: 371-376.
    CrossRef  |  
  21. Jha, A., K.M. Duffield, M.R. Ness, S. Ravoori and G. Andrews et al., 2015. Curcumin-inspired cytotoxic 3, 5-bis (arylmethylene)-1-(N-(ortho-substituted aryl) maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors. Bioorg. Med. Chem., 23: 6404-6417.
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  22. Gunathilake, K.D.P.P. and H.P.V. Rupasinghe, 2015. Recent perspectives on the medicinal potential and chemistry of ginger. Botanics: Targets Ther., 5: 55-63.
  23. Fernando, W., H.P.V. Rupasinghe and D.W. Hoskin, 2015. Regulation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling by plant flavonoids. Mini Rev. Med. Chem., 15: 479-489.
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  24. Casey, S.C., A. Amedei, K. Aquilano, A.S. Azmi and F. Benencia et al., 2015. Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars Cancer Biol., 35: S199-S223.
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  25. Block, K.I., C. Gyllenhaal, L. Lowe, A. Amedei and A.R. Amin et al., 2015. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars Cancer Biol., 35: S276-S304.
    CrossRef  |  Direct Link  |  
  26. Bhullar, K.S., A. Jha and H.V. Rupasinghe, 2015. Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. Chemico-Biol. Interact., 242: 107-122.
    CrossRef  |  Direct Link  |  
  27. Bhullar, K.S. and H.P.V. Rupasinghe, 2015. Partridgeberry polyphenols protect primary cortical and hippocampal neurons against β-amyloid toxicity. Food Res. Int., 74: 237-249.
    CrossRef  |  
  28. Bhullar, K.B. and H.P.V. Rupasinghe, 2015. Antioxidant and cytoprotective properties of partridgeberry polyphenols. Food Chem., 168: 595-605.
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  29. Arumuggam, N., N.A. Bhowmick and H.P. Rupasinghe, 2015. A review: Phytochemicals targeting JAK/STAT signaling and IDO expression in cancer. Phytother. Res., 29: 805-817.
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  30. Warford, J., Q.R. Jones, M. Nichols, V. Sullivan, H.V. Rupasinghe and G.S. Robertson, 2014. The flavonoid-enriched fraction AF4 suppresses neuroinflammation and promotes restorative gene expression in a mouse model of experimental autoimmune encephalomyelitis. J. Neuroimmunol., 268: 71-83.
    CrossRef  |  
  31. Sudan, S. and H.P.V. Rupasinghe, 2014. Quercetin-3-O-glucoside induces human DNA topoisomerase II inhibition, cell cycle arrest and apoptosis in hepatocellular carcinoma cells. Anti-Cancer Res., 34: 1691-1699.
    Direct Link  |  
  32. Sudan, S. and H.P.V. Rupasinghe, 2014. Flavonoid-enriched apple fraction AF4 induces cell cycle arrest, DNA topoisomerase II inhibition and apoptosis in human liver cancer HepG2 cells. Nutr. Cancer, 66: 1237-1246.
    CrossRef  |  
  33. Sekhon-Loodu, S., A. Catalli, M. Kulka, Y. Wang, F. Shahidi and H.P.V. Rupasinghe, 2014. Combination of apple flavonols and omega-3 fatty acid-rich fish oil improves the efficacy of lowering blood C-reactive protein in rats with hypercholesterolemia and acute inflammation. Nutr. Res., 34: 535-543.
  34. Nair, S.V.G., M. Hettihewa and H.P.V. Rupasinghe, 2014. Apoptotic and inhibitory effects on cell proliferation of hepatocellular carcinoma HepG2 cells by methanol leaf extract of Costus speciosus. BioMed Res. Int., Vol. 2014. 10.1155/2014/637098.
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  35. Nair, S.V. and H.P.V. Rupasinghe, 2014. Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression. PLoS One, Vol. 9. 10.1371/journal.pone.0107149.
    CrossRef  |  
  36. Gunathilake, K.D.P.P., L.J. Yu and H.P. Rupasinghe, 2014. Reverse osmosis as a potential technique to improve antioxidant properties of fruit juices used for functional beverages. Food Chem., 148: 335-341.
    CrossRef  |  
  37. Bhullar, K.B., G. Lassalle-Claux, M. Touaibia and H.P.V. Rupasinghe, 2014. Antihypertensive effect of caffeic acid and its analogs through dual renin-angiotensin-aldosterone system inhibition. Eur. J. Pharmacol., 730: 125-132.
  38. Bhullar, K.B. and H.P.V. Rupasinghe, 2014. In vitro regulation of enzymes of the renin-angiotensin-aldosterone system by isoquercitrin, phloridzin and their long chain fatty acid derivatives. Functional Foods Health Dis., 4: 208-221.
  39. Ziaullah, K.S. Bhullar, S.N. Warnakulasuriya and H.P.V. Rupasinghe, 2013. Biocatalytic synthesis, structural elucidation, antioxidant capacity and tyrosinase inhibition activity of long chain fatty acid acylated derivatives of phloridzin and isoquercitrin. Bioorg. Med. Chem., 21: 684-692.
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  40. Ziaullah and H.P.V. Rupasinghe, 2013. An efficient microwave-assisted enzyme-catalyzed regioselective synthesis of long chain acylated derivatives of flavonoid glycosides. Tetrahedron Lett., 54: 1933-1937.
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  41. Yu, L. and H.P.V. Rupasinghe, 2013. Improvement of cloud stability, yield and β-carotene content of carrot juice by process modification. Food Sci. Technol. Int., 19: 399-406.
    CrossRef  |  PubMed  |  
  42. Thilakarathna, S.H., H.P.V. Rupasinghe and P.W. Needs, 2013. Apple peel bioactive rich extracts effectively inhibit in vitro human LDL cholesterol oxidation. Food Chem., 138: 463-470.
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  43. Thilakarathna, S.H. and H.P.V. Rupasinghe, 2013. Flavonoid bioavailability and attempts for bioavailability enhancement. Nutrients, 5: 3367-3387.
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  44. Taylor, N., A.M. Hammermeister, H.P.V. Rupasinghe and K. Pruski, 2013. Characterization of Ribes nigrum in relation to fruit maturity and genotype. Acta Hortic., 1001: 199-205.
  45. Sekhon-Loodu, S., S.N. Warnakulasuriya, H.P.V. Rupasinghe and F. Shahidi, 2013. Antioxidant ability of fractionated apple peel phenolics to inhibit fish oil oxidation. Food Chem., 140: 189-196.
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  46. Rupasinghe, H.P.V., I. Parmar and L. Yu, 2013. Value-added fruit processing and human health: Global perspectives. Ethiopian J. Applied Sci. Technol., 3: 27-39.
  47. Parmar, I. and H.P.V. Rupasinghe, 2013. Bio-conversion of apple pomace into ethanol and acetic acid: Enzymatic hydrolysis and fermentation. Bioresour. Technol., 130: 613-620.
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  48. Nandasiri, R. and H.P.V. Rupasinghe, 2013. Inhibition of low density lipoprotein oxidation and angiotensin converting enzyme in vitro by functional fruit vinegar beverages. J. Food Process. Beverages, 1: 5-10.
  49. Gunathilake, K.D.P.P., Y. Wang and H.P.V. Rupasinghe, 2013. Hypocholesterolemic and hypotensive effects of a fruit-based functional beverage in spontaneously hypertensive rats fed with cholesterol-rich diet. J. Funct. Foods, 5: 1392-1401.
    CrossRef  |  Direct Link  |  
  50. Gunathilake, K.D.P.P., H.P.V. Rupasinghe and N.L. Pitts, 2013. Formulation and characterization of a bioactives-enriched fruit beverage designed for cardio-protection. Food Res. Int., 52: 535-541.
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  51. Gibson, L., H.P.V. Rupasinghe, C.F. Forney and L. Eaton, 2013. Characterization of changes in polyphenols, antioxidant capacity and physico-chemical parameters during lowbush blueberry fruit ripening. Antioxidants, 2: 216-229.
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  52. Gao, J., H.P.V. Vasantha and N.L. Pitts, 2013. Characterisation of malolactic conversion by Oenococcus oeni to reduce the acidity of apple juice. Int. J. Food Sci. Technol., 48: 1018-1027.
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  53. Forsido, S.F., H.P.V. Rupasinghe and T. Astatkie, 2013. Antioxidant capacity, total phenolics and nutritional content in selected ethiopian staple food ingredients. Int. J. Food Sci. Nutr., 64: 915-920.
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  54. Chen, Y., L.J. Yu and H.P.V. Rupasinghe, 2013. Effect of thermal and non‐thermal pasteurisation on the microbial inactivation and phenolic degradation in fruit juice: A mini‐review. J. Sci. Food Agric., 93: 981-986.
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  55. Bhullar, K.S., A. Jha, D. Youssef and H.P.V. Rupasinghe, 2013. Curcumin and its carbocyclic analogs: Structure-activity in relation to antioxidant and selected biological properties. Molecules, 18: 5389-5404.
  56. Yu, L.J. and H.V.P. Rupasinghe, 2012. Effect of acidification on quality and shelf-life of carrot juice. Can. J. Plant Sci., 92: 1113-1120.
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  57. Thilakarathna, S.H., Y. Wang, H.P.V. Rupasinghe and K. Ghanam, 2012. Apple peel flavonoid-and triterpene-enriched extracts differentially affect cholesterol homeostasis in hamsters. J. Funct. Foods, 4: 963-971.
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  58. Thilakarathna, S.H. and H.P.V. Rupasinghe, 2012. Anti-atherosclerotic effects of fruit bioactive compounds: A review of current scientific evidence. Can. J. Plant Sci., 92: 407-419.
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  59. Rupasinghe, H.P.V., L. Yu, K. Bhullar and B. Bors, 2012. Haskap (Lonicera caerulea): A new berry crop with high antioxidant capacity. Can. J. Plant Sci., 92: 1311-1317.
  60. Ratnasooriya, C.C., H.P.V. Rupasinghe and N.L. Pitts, 2012. Physicochemical and sensory evaluation of non-alcoholic wine-like beverages prepared from selected grape cultivars. J. Nutr. Food Sci., Vol. 2 .
    Direct Link  |  
  61. Ratnasooriya, C.C. and H.P.V. Rupasinghe, 2012. Extraction of phenolic compounds from grapes and their pomace using β-cyclodextrin. Food Chem., 134: 625-631.
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  62. Parmar, I. and H.P.V. Rupasinghe, 2012. Optimization of dilute acid-based pretreatment and application of laccase on apple pomace. Bioresour. Technol., 124: 433-439.
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  63. Keddy, P.G., K. Dunlop, J. Warford, M.L. Samson, Q.R.D. Jones, H.P.V. Rupasinghe and G.S. Robertson, 2012. Neuroprotective and anti-inflammatory effects of the flavonoid-enriched fraction AF4 in a mouse model of hypoxic-ischemic brain injury. PLoS One, Vol. 7 10.1371/journal.pone.0051324.
    CrossRef  |  PubMed  |  
  64. Jones, Q.R.D., J. Warford, H.P.V. Rupasinghe and G.S. Robertson, 2012. Target-based selection of flavonoids for neurodegenerative disorders. Trends Pharmacol. Sci., 33: 602-610.
    Direct Link  |  
  65. Glover, K.E., S. Budge, M. Rose, H.P.V. Rupasinghe, L. MacLaren, J. Green-Johnson and A.H. Fredeen, 2012. Effect of feeding fresh forage and marine algae on the fatty acid composition and oxidation of milk and butter. J. Dairy Sci., 95: 2797-2809.
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  66. Gao, J. and H.P.V. Rupasinghe, 2012. Characterization of 'Honeycrisp' and 'mcintosh' apple juice quality in relation to delayed cooling treatments. Open Food Sci. J., 6: 12-15.
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  67. Gao, G. and H.P.V. Rupasinghe, 2012. Nutritional, physicochemical and microbial quality of ultrasound-treated apple-carrot juice blends. Food Nutr. Sci., 3: 212-218.
  68. Erkan, N., Z. Tao, H.P.V. Rupasinghe, B. Uysal and B.S. Oksal, 2012. Antibacterial activities of essential oils extracted from leaves of Murraya koenigii by solvent-free microwave extraction and hydro-distillation. Nat. Prod. Commun., 7: 121-124.
    PubMed  |  
  69. Balasuriya, N. and H.P.V. Rupasinghe, 2012. Antihypertensive properties of flavonoid-rich apple peel extract. Food Chem., 135: 2320-2325.
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  70. Rupasinghe, H.P.V., P. Kathirvel and G.M. Huber, 2011. Ultrasonication-assisted solvent extraction of quercetin glycosides from 'Idared' apple peels. Molecules, 16: 9783-9791.
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  71. Proctor, J.T.A., J. A. Sullivan, H.P.V. Rupasinghe and C.J.C. Jackson, 2011. Morphological and ginsenoside differences among North American ginseng leaves. J. Ginseng Res., 35: 155-161.
  72. Muche, B.M. and H.P.V. Rupasinghe, 2011. Natural antimicrobial agents of cinnamon (Cinnamomum zeylanicum L. and C. cassia) and vanilla (Vanilla planifola, V. pompon and V. tahitensis) for extending the shelf-life of fresh-cut fruits. Ethiopian J. Applied Sci., Technol., 2: 1-13.
  73. Joshi, A.P.K., H.P.V. Rupasinghe, and S. Khanizadeh, 2011. Impact of drying processes on bioactive phenolics, vitamin C and antioxidant capacity of red-fleshed apple slices. J. Food Process. Preserv., 35: 453-457.
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  74. Joshi, A.P.K., H.P.V. Rupasinghe and N.L. Pitts, 2011. Comparison of nonfried apple snacks with commercially available fried snacks. Food Sci. Technol. Int., 17: 249-255.
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  75. Balasuriya, B.W.N. and H.P.V. Rupasinghe, 2011. Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension. Funct. Foods Health Dis., 5: 172-188.
    Direct Link  |  
  76. Rupasinghe, H.P.V., N. Erkan and A. Yasmin, 2010. Antioxidant protection of eicosapentaenoic acid and fish oil oxidation by polyphenolic-enriched apple skin extract. J. Agric. Food Chem., 58: 1233-1239.
    PubMed  |  
  77. Rupasinghe, H.P.V., G.M. Huber, C. Embree and P.L. Forsline, 2010. Red-fleshed apple as a source for functional beverages. Can. J. Plant Sci., 90: 95-100.
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  78. Rupasinghe, H.P.V., C.M. Ronalds, B. Rathgeber and R.A. Robinson, 2010. Absorption and tissue distribution of dietary quercetin and quercetin glycosides of apple skin in broiler chickens. J. Sci. Food Agric., 90: 1172-1178.
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  79. Rupasinghe, H.P.V and A. Yasmin, 2010. Inhibition of oxidation of aqueous emulsions of omega-3 fatty acids and fish oil by phloretin and phloridzin. Molecules, 15: 251-257.
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  80. Ratnasooriya, C.C., H.P.V. Rupasinghe and A.R. Jamieson, 2010. Juice quality and polyphenol concentration of fresh fruits and pomace of selected Nova Scotia-grown grape cultivars. Can. J. Plant Sci., 90: 193-205.
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  81. Joshi, A.P.K., H.P.V. Rupasinghe and N.L. Pitts, 2010. Sensory and nutritional quality of the apple snacks prepared by vacuum impregnation process. J. Food Qual., 33: 758-767.
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  82. Joshi, A.P.K. and H.P.V. Rupasinghe, 2010. Optimization of bioactive fortification in apple snacks through vacuum impregnation using response surface methodology. Food Nutr. Sci., 2: 45-52.
  83. Rupasinghe, H.P.V., L. Wang, N.L. Pitts and T. Astatkie, 2009. Baking and sensory characteristics of muffins incorporated with apple skin powder. J. Food Qual., 32: 685-694.
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  84. Khanizadeh, S., R. Tsao, D. Rekika, R. Yang, M.T. Charles and H.P.V. Rupasinghe, 2009. Advances in fruit breeding in eastern canada-Role of phytochemicals in designing specialty fruits. Acta Hortic., 814: 205-208.
  85. Khanizadeh, S., L. Ding, R. Tsao, D. Rekika, R. Yang, M.T. Charles and H.P.V. Rupasinghe, 2009. Phytochemical profiles of selected processing apple genotypes. Acta Hortic., 814: 545-550.
  86. Huber, G.M., H.P.V. Rupasinghe and F. Shahidi, 2009. Inhibition of oxidation of omega-3 polyunsaturated fatty acids and fish oil by quercetin glycosides. Food Chem., 117: 290-295.
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  87. Huber, G.M. and H.P. Rupasinghe, 2009. Phenolic profiles and antioxidant properties of apple skin extracts. J. Food Sci., 74: C693-C700.
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  88. Hossain, M.A., S.M. Salehuddin, M.J. Kabir, S.M.M. Rahman and H.P.V. Rupasinghe, 2009. Sinensetin, rutin, 3'-hydroxy-5, 6, 7, 4'-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of the skin of apple fruit. Food Chem., 113: 185-190.
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  89. Soundararajan, R., A.D. Wishart, H.P.V. Rupasinghe, M. Arcellana-Panlilio, C.M Nelson, M. Mayne and G.S. Robertson, 2008. Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis. J. Biol. Chem., 284: 2231-2245.
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  90. Rupasinghe, H.P.V., L. Wang, G.M. Huber and N.L. Pitts, 2008. Effect of baking on dietary fibre and phenolics of muffins incorporated with apple skin powder. Food Chem., 107: 1217-1224.
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  91. Rupasinghe, H.P.V. and C. Kean, 2008. Polyphenol concentrations in apple processing by-products determined using electrospray ionization mass spectrometry. Can. J. Plant Sci., 88: 759-762.
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  92. Muthuswamy, S., H.P.V. Rupasinghe and G.W. Stratton, 2008. Antimicrobial effect of cinnamon bark extract on Escherichia coli O157: H7, Listeria innocua and fresh-cut apple slices. J. Food Safety, 28: 534-549.
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  93. Khanizadeh, S., R. Tsao, D. Rekika, R. Yang, M.T. Charles and H.P.V. Rupasinghe, 2008. Polyphenol composition and total antioxidant capacity of selected apple genotypes for processing. J. Food Compos. Anal., 21: 396-401.
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  94. Hargreaves, J.C., M. Adl, P.R. Warman and H.P. Rupasinghe, 2008. The effects of organic and conventional nutrient amendments on strawberry cultivation: Fruit yield and quality. J. Sci. Food Agric., 88: 2669-2675.
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  95. Hargreaves, J., M.S. Adl, P.R. Warman and H.P.V. Rupasinghe, 2008. The effects of organic amendments on mineral element uptake and fruit quality of raspberries. Plant Soil, 308: 213-226.
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  96. Rupasinghe, H.P.V., C. Kean, D. Nichols and C. Embree, 2007. Orchard waste as a valuable bio-resource: A chemical composition analysis. Acta Hortic., 737: 17-23.
  97. Rupasinghe, H.P.V. and S. Clegg, 2007. Total antioxidant capacity, total phenolic content, mineral elements and histamine concentrations in wines of different fruit sources. J. Food Compos. Anal., 20: 133-137.
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  98. Muthuswamy, S. and H.P.V. Rupasinghe, 2007. Fruit phenolics as natural antimicrobial agents: Selective antimicrobial activity of catechin, chlorogenic acid and phloridzin. J. Food Agric. Environ., 5: 81-85.
  99. Khanizadeh, S., D. Li, R. Tsao, D. Rekika and R. Yang et al., 2007. Phytochemical distribution among selected advanced apple genotypes developed for fresh market and processing. J. Agric. Food Environ. Sci., Vol. 1 .
  100. Joshi, A.P.K., H.P.V. Rupasinghe, N.L. Pitts and S. Khanizadeh, 2007. Biochemical characterization of enzymatic browning in selected apple genotypes. Can. J. Plant Sci., 87: 1067-1074.
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  101. Rupasinghe, H.P.V., S. Jayasankar and W. Lay, 2006. Variation in total phenolics and antioxidant capacity among European plum genotypes. Sci. Hortic., 108: 243-246.
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  102. Rupasinghe, H.P.V., J. Boulter-Bitzer, T. Ahn and J.A. Odumeru, 2006. Vanillin inhibits pathogenic and spoilage microorganisms in vitro and aerobic microbial growth in fresh-cut apples. Food Res. Int., 39: 575-580.
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  103. Rupasinghe, H.P.V., J. Boulter-Bitzer and J.A. Odumeru, 2006. Lactic acid improves the efficacy of anti-microbial washing solutions for apples. J. Food Agric. Environ., 4: 44-48.
  104. Rupasinghe, H.P.V., D.P. Murr, J.R. DeEll and J.A. Odumeru, 2005. Influence of 1-methylcyclopropene (1-MCP) and NatureSealTM on the quality of fresh-cut ''Empire'' and ''Crispin'' apples. J. Food Qual., 28: 289-307.
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  105. McKellar, R.C., H.P.V. Rupasinghe, X. Lu and K.P. Knight, 2005. Analysis and classification of fruit and grape wines from different wineries using the electronic nose. J. Sci. Food Agric., 85: 2391-2396.
  106. Zobayed, S.M.A., S.J. Murch, H.P.V. Rupasinghe, J.G. De Boer, B.W. Glickman and P.K. Saxena, 2004. Optimized system for biomass production, chemical characterization and evaluation of chemo-preventive properties of Scutellaria baicalensis Georgi. Plant Sci., 167: 439-446.
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  107. Zobayed, S.M.A., S.J. Murch, H.P.V. Rupasinghe and P.K. Saxena, 2004. In vitro production and chemical characterization of St. Johns wort (Hypericum perforatum L. cv. New Stem). Plant Sci., 166: 333-340.
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  108. Rupasinghe, H.P.V., C.J.C. Jackson, V. Poysa and J. Kinjo, 2004. A rapid method to analyze saponin precursors in soybean (Glycine max (L.) Merrill). Acta Hortic., 629: 139-143.
  109. Murch, S.J., H.P.V. Rupasinghe, D. Goodenowe and P.K. Saxena, 2004. A metabalomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: Discovery of novel compounds. Plant Cell Rep., 23: 419-425.
  110. Jackson, C.J.C., H.P.V. Rupasinghe, T. Ayanbadejo, P. Martos and J. Schooley, 2004. Assessment of Ontario-grown ginseng (Panax quinquefolius L.) for nutritional quality and food safety. Acta Hortic., 629: 115-121.
  111. Zobayed, S.M.A., S.J. Murch, H.P.V. Rupasinghe and P.K. Saxena, 2003. Elevated carbon supply altered hypericin and hyperforin contents of St. John's wort (Hypericum perforatum L. cvNew Stem) grown in bioreactors. Plant Cell Tissue Organ Cult., 75: 143-149.
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  112. Whiting, M.D., H.P.V. Rupasinghe, D.P. Murr, G. Paliyath and D.D. Rowan, 2003. Effect of alpha-farnesene and its metabolites on membrane properties of 'Delicious' apples. Acta Hortic., 628: 627-633.
  113. Rupasinghe, H.P.V., K.C. Almquist, G. Paliyath, D.P. Murr, T.E. Elthon and A.C. Purvis, 2003. Involvement of the alternative oxidase (AOX) in superficial scald: Isolation and sequence analysis of the apple AOX1 cDNA. Acta Hortic., 628: 481-486.
  114. Rupasinghe, H.P.V., G. Paliyath and D.P. Murr, 2003. A review: Biosynthesis of isoprenoids in higher plants. J. Plant Physiol. Mol. Biol., 9: 19-28.
  115. Rupasinghe, H.P.V., C.J.C. Jackson, V. Poysa, C. Di Berardo, J.D. Bewley and J. Jenkinson, 2003. Soyasapogenol A and B distribution in soybean (Glycine max L. Merr.) in relation to seed physiology, genetic variability and growing location. J. Agric. Food Chem., 51: 5888-5894.
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  116. Murch, S.J., K. Haq, H.P.V. Rupasinghe and P.K. Saxena, 2003. Nickel contamination affects growth and secondary metabolite composition of St. John's wort ( Hypericum perforatum L.). Environ. Exp. Bot., 49: 251-257.
  117. Jackson, C.J.C., J.P. Dini, C. Lavandier, H. Faulkner, H.P.V. Rupasinghe and J.T.A. Proctor, 2003. Ginsenoside content of North American ginseng (Panax quinquefolius L. Araliaceae) in relation to plant development and growing locations. J. Ginseng Res., 27: 135-140.
  118. Campeau, C., J.T. Proctor, C.J.C. Jackson and H.P.V. Rupasinghe, 2003. Rust-spotted North American ginseng roots: Phenolic, antioxidant, ginsenoside and mineral nutrient content. HortScience, 38: 179-182.
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  119. Murch, S.J., H.P.V. Rupasinghe and P.K. Saxena, 2002. An in vitro and hydroponic growing system for hypericin, pseudohypericin and hyperforin production of St. John's wort (Hypericum perforatum L. CV new stem). Planta Med., 68: 1108-1112.
  120. Jackson, C.J., J.P. Dini, C. Lavandier, H.P.V. Rupasinghe and H. Faulkner et al., 2002. Effects of processing on the content and composition of isoflavones during manufacturing of soy beverage and tofu. Process Biochem., 37: 1117-1123.
  121. DeEll, J.R., D.P. Murr, M.D. Porteous and H.P.V. Rupasinghe, 2002. Influence of temperature and duration of 1-methylcyclopropene (1-MCP) treatment on apple quality. Postharvest Biol. Technol., 24: 349-353.
  122. Rupasinghe, H.P.V., K.C. Almquist, G. Paliyath and D.P. Murr, 2001. Cloning of hmg1 and hmg2 cDNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase and their expression and activity in relation to α-farnesene synthesis in apple. Plant Physiol. Biochem., 39: 933-947.
  123. Rupersinghe, H.P.V., D.P. Murr, G. Paliyath and L. Skog, 2000. Inhibitory effect of 1-MCP on ripening and superficial scald development in 'McIntosh' and delicious apples. J. Hort. Sci. Biotechnol., 75: 271-276.
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  124. Rupasinghe, H.P.V., G. Paliyath and D.P. Murr, 2000. Sesquiterpene α-farnesene synthase: partial purification, characterization and activity in relation to superficial scald development in apples. J. Am. Soc. Hort. Sci., 125: 111-119.
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  125. Rupasinghe, H.P.V., D.P. Murr, G. Paliyath and J.R. DeEll, 2000. Suppression of a-farnesene synthesis in 'Delicious' apples by aminoethoxyvinylglycine (AVG) and 1-methylcyclopropene (1-MCP). J. Plant Phyiol. Mol. Biol., 6: 195-198.
  126. Rupasinghe, H.P.V. and R.J. Gladon, 2000. Glutamic acid and 5-aminolevulenic acid enhance System 2 ethylene in ripening tomato fruits. J. Plant Physiol. Mol. Biol., 6: 27-33.
  127. Rupasinghe, H.P.V., G. Paliyath and D.P. Murr, 1998. Biosynthesis of α-farnesene and its relation to superficial scald development in 'Delicious' apples. J. Am. Soc. Hort. Sci., 123: 882-886.
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  128. Rupasinghe, H.P.V., B.C.N. Peiris and S.W. Wijerathnam, 1993. A case study on identification and assessment of postharvest losses of tomato (Lycoperisicon escuentum Mill). Trop. Agric. Res., 4: 41-47.
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