Dr. Danish  Sayed
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Dr. Danish Sayed

Research Scientist
University of Medicine and Dentistry of New Jersey, USA


Highest Degree
Ph.D. in Cardiovascular Diseases from University of Medicine and Dentistry School, New Jersey, USA

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Area of Interest:

Biomedical Sciences
100%
Molecular Biology
62%
Signal Transduction
90%
Cardiovascular Research
75%
Physiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Minghue, H., Z. Yang, D. Sayed, H. Minzhen, G. Shumin, L. Lin, S.H. Yoon andM. Abdellatif, 2012. GATA4 expression is primarily regulated via a mir-26-dependent posttranscriptional mechanism during cardiac hypertrophy. Cardiovasc Res., 4 .
    PubMed  |  
  2. Sayed, D. and M. Abdellatif, 2011. MicroRNAs in development and disease. Physiol. Rev., 91: 827-887.
    CrossRef  |  
  3. Sayed, D., H. Minzhen, Z. Yang, S. Rani and M. Abdellatif, 2010. MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas Ligand J. Bio. Chem., 285: 20281-20290.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Rani, S., H. Minzhen, D. Sayed, Y. Lin, V. Dorothy and M. Abdellatif, 2010. An antagonism between the AKT and β -adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p. Cell. Signall., 22: 1054-1062.
  5. Sayed, D. and M. Abdellatif, 2010. AKT-ing via microRNA. Cell Cycle, 9: 3213-3237.
    CrossRef  |  PubMed  |  
  6. Rani, S., H. Minzhen, D. Sayed, H. Vashistha and A. Malhotra et al., 2009. Downregulation of MiR-199a derepresses hypoxia-inducible factor-1α and sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Cir. Res., 104: 879-886.
    CrossRef  |  
  7. Sayed, D., S. Rane and M. Abdellatif, 2009. MicroRNAs challenge the status quo of therapeutic targeting. J. Cardiovasc. Transl. Res., 2: 100-107.
    PubMed  |  
  8. Sayed, D., S. Rane, J. Lypowy, M. He and I.Y. Chen et al., 2008. MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. Mol. Biol. Cell, 19: 3272-3282.
    PubMed  |  
  9. Sayed, D., H. Chull, I.Y. Chen, J. Lypowy and M. Abdellatif, 2007. MicroRNA play an essential role in the development of cardiac hypertrophy. Cir. Res., 100: 416-424.
    CrossRef  |  
  10. Rane, S., D. Sayed and M. Abdellatif, 2007. MicroRNA with a MacroFunction. Cell Cycle, 6: 1850-1855.
  11. Chen, I.Y., J. Lupowy, J. Pain, D. Sayed and S. Grinberg et al., 2006. Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2alpha. J. Biol. Chem., 281: 19369-19377.
    PubMed  |