Dr. Anthony Albert Grace
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Dr. Anthony Albert Grace

Professor
University of Pittsburgh, USA

Highest Degree
Ph.D. in Pharmacology from Yale University, USA

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Area of Interest:

Pharmacology and Toxicology
100%
Neuroscience
62%
Psychiatry
90%
Psychology
75%
Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Scharfman, H.E., A.M. Kanner, A. Friedman, I. Blumcke and C.E. Crocker et al., 2018. Epilepsy as a network disorder (2): What can we learn from other network disorders such as dementia and schizophrenia and what are the implications for translational research? Epilepsy Behav., 78: 302-312.
    CrossRef  |  Direct Link  |  
  2. Modinos, G., F. Simsek, J. Horder, M. Bossong and I. Bonoldi et al., 2018. Cortical GABA in subjects at ultra-high risk of psychosis: Relationship to negative prodromal symptoms. Int. J. Neuropsychopharmacol., 21: 114-119.
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  3. Hasbi, A., M.L. Perreault, M.Y. Shen, T. Fan and T. Nguyen et al., 2018. Activation of dopamine D1-D2 receptor complex attenuates cocaine reward and reinstatement of cocaine-seeking through inhibition of DARPP-32, ERK and ΔFosB. Front. Pharmacol., Vol. 8. 10.3389/fphar.2017.00924.
    CrossRef  |  Direct Link  |  
  4. Gill, K.M., S.A. Miller and A.A. Grace, 2018. Impaired contextual fear-conditioning in MAM rodent model of schizophrenia. Schizophrenia Res., 195: 343-352.
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  5. Zhu, X., F.V. Gomes and A.A. Grace, 2017. The methylazoxymethanol acetate rat model: Molecular and epigenetic effect in the developing prefrontal cortex. J. Neurochem., 143: 264-267.
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  6. Winton-Brown, T., A. Schmidt, J.P. Roiser, O.D. Howes and A. Egerton et al., 2017. Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis. Transl. Psychiatry, Vol. 7. 10.1038/tp.2017.174.
    CrossRef  |  Direct Link  |  
  7. Voon, V., T.C. Napier, M.J. Frank, V. Sgambato-Faure and A.A. Grace et al., 2017. Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: An update. Lancet Neurol., 16: 238-250.
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  8. Steullet, P., J.H. Cabungcal, J. Coyle, M. Didriksen and K. Gill et al., 2017. Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia. Mol. Psychiatry, 22: 936-943.
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  9. Rincon-Cortes, M. and A.A. Grace, 2017. Sex-dependent effects of stress on immobility behavior and VTA dopamine neuron activity: Modulation by ketamine. Int. J. Neuropsychopharmacol., 20: 823-832.
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  10. Perreault, M.L., T. Fan, T.J. Banasikowski, A.A. Grace and S.R. George, 2017. The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction. Eur. J. Neurosci., 46: 2015-2025.
    CrossRef  |  Direct Link  |  
  11. Moreines, J.L., Z.L. Owrutsky, K.G. Gagnon and A.A. Grace, 2017. Divergent effects of acute and repeated quetiapine treatment on dopamine neuron activity in normal vs. chronic mild stress induced hypodopaminergic states. Transl. Psychiatry, Vol. 7. 10.1038/s41398-017-0039-9.
    CrossRef  |  Direct Link  |  
  12. Moreines, J.L., Z.L. Owrutsky and A.A. Grace, 2017. Involvement of infralimbic prefrontal cortex but not lateral habenula in dopamine attenuation after chronic mild stress. Neuropsychopharmacology, 42: 904-913.
    CrossRef  |  Direct Link  |  
  13. Lipski, W.J., S.M. Dibble, L. Rinaman and A.A. Grace, 2017. Psychogenic stress activates c-fos in nucleus accumbens-projecting neurons of the hippocampal ventral subiculum. Int. J. Neuropsychopharmacol., 20: 855-860.
    CrossRef  |  Direct Link  |  
  14. Grace, A.A., 2017. Dopamine system dysregulation and the pathophysiology of schizophrenia: Insights from the methylazoxymethanol acetate model. Biol. Psychiatry, 81: 5-8.
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  15. Gomes, F.V. and A.A. Grace, 2017. Adolescent stress as a driving factor for schizophrenia development-a basic science perspective. Schizophrenia Bull., 43: 486-489.
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  16. Belujon, P. and A.A. Grace, 2017. Dopamine system dysregulation in major depressive disorders. Int. J. Neuropsychopharmacol., 20: 1036-1046.
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  17. Zimmerman, E.C. and A.A. Grace, 2016. The nucleus reuniens of the midline thalamus gates prefrontal-hippocampal modulation of ventral tegmental area dopamine neuron activity. J. Neurosci., 36: 8977-8984.
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  18. Qi, Z., P.Y. Gina, F. Tretter, O. Pogarell, A.A. Grace and E.O. Voit, 2016. A heuristic model for working memory deficit in schizophrenia. Biochim. Biophys. Acta (BBA)-Gen. Subj., 1860: 2696-2705.
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  19. Myrga, J.M., S.B. Juengst, M.D. Failla, Y.P. Conley, P.M. Arenth, A.A. Grace and A.K. Wagner, 2016. COMT and ANKK1 genetics interact with depression to influence behavior following severe TBI: An initial assessment. Neurorehabil. Neural Repair, 30: 920-930.
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  20. Harun, R., K.M. Hare, E.M. Brough, M.J. Munoz and C.M. Grassi et al., 2016. Fast-scan cyclic voltammetry demonstrates that L-DOPA produces dose-dependent, regionally selective bimodal effects on striatal dopamine kinetics in vivo. J. Neurochem., 136: 1270-1283.
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  21. Grace, A.A., 2016. Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression. Nat. Rev. Neurosci., 17: 524-532.
    CrossRef  |  PubMed  |  Direct Link  |  
  22. Gomes, F.V., M. Rincon-Cortes and A.A. Grace, 2016. Adolescence as a period of vulnerability and intervention in schizophrenia: Insights from the MAM model. Neurosci. Biobehav. Rev., 70: 260-270.
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  23. Gomes, F.V. and A.A. Grace, 2016. Prefrontal cortex dysfunction increases susceptibility to schizophrenia-like changes induced by adolescent stress exposure. Schizophrenia Bull., 43: 592-600.
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  24. Du, Y. and A.A. Grace, 2016. Loss of parvalbumin in the hippocampus of MAM schizophrenia model rats is attenuated by peripubertal diazepam. Int. J. Neuropsychopharmacol., Vol. 19, No. 11. 10.1093/ijnp/pyw065.
    CrossRef  |  Direct Link  |  
  25. Du, Y. and A.A. Grace, 2016. Amygdala hyperactivity in MAM model of schizophrenia is normalized by peripubertal diazepam administration. Neuropsychopharmacology, 41: 2455-2462.
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  26. Chang, C.H. and A.A. Grace, 2016. Inhibitory modulation of orbitofrontal cortex on medial prefrontal cortex-amygdala information flow. Cerebral Cortex, 28: 1-8.
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  27. Belujon, P., N.L. Jakobowski, H.K. Dollish and A.A. Grace, 2016. Withdrawal from acute amphetamine induces an amygdala-driven attenuation of dopamine neuron activity: Reversal by ketamine. Neuropsychopharmacology, 41: 619-627.
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  28. Richetto, J., M.A. Labouesse, M.M. Poe, J.M. Cook, A.A. Grace, M.A. Riva and U. Meyer, 2015. Behavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'FS-CH3 in an immune-mediated neurodevelopmental disruption model. Int. J. Neuropsychopharmacol., Vol. 18, No. 4. 10.1093/ijnp/pyu055.
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  29. Napier, T.C., J.C. Corvol, A.A. Grace, J.D. Roitman, J. Rowe, V. Voon and A.P. Strafella, 2015. Linking neuroscience with modern concepts of impulse control disorders in Parkinson's disease. Movement Disord., 30: 141-149.
    CrossRef  |  Direct Link  |  
  30. Modinos, G., P. Allen, A.A. Grace and P. McGuire, 2015. Translating the MAM model of psychosis to humans. Trends Neurosci., 38: 129-138.
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  31. Gomes, F.V., F.S. Guimaraes and A.A. Grace, 2015. Effects of pubertal cannabinoid administration on attentional set-shifting and dopaminergic hyper-responsivity in a developmental disruption model of schizophrenia. Int. J. Neuropsychopharmacol., Vol. 18, No. 2. 10.1093/ijnp/pyu018.
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  32. Deserno, L., Q.J. Huys, R. Boehme, R. Buchert and H.J. Heinze et al., 2015. Ventral striatal dopamine reflects behavioral and neural signatures of model-based control during sequential decision making. Proc. Natl. Acad. Sci. USA., 112: 1595-1600.
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  33. Deserno, L., A. Beck, Q.J. Huys, R.C. Lorenz and R. Buchert et al., 2015. Chronic alcohol intake abolishes the relationship between dopamine synthesis capacity and learning signals in the ventral striatum. Eur. J. Neurosci., 41: 477-486.
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  34. Chase, H.W., M. Clos, S. Dibble, P. Fox, A.A. Grace, M.L. Phillips and S.B. Eickhoff, 2015. Evidence for an anterior-posterior differentiation in the human hippocampal formation revealed by meta-analytic parcellation of fMRI coordinate maps: Focus on the subiculum. NeuroImage, 113: 44-60.
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  35. Chang, C.H. and A.A. Grace, 2015. Dopaminergic modulation of lateral amygdala neuronal activity: Differential D1 and D2 receptor effects on thalamic and cortical afferent inputs. Int. J. Neuropsychopharmacol., Vol. 18, No. 8. 10.1093/ijnp/pyv015.
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  36. Belujon, P. and A.A. Grace, 2015. Regulation of dopamine system responsivity and its adaptive and pathological response to stress. Proc. R. Soc. B: Biol. Sci., Vol. 282. 10.1098/rspb.2014.2516.
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  37. Sesia, T., B. Bizup and A.A. Grace, 2014. Nucleus accumbens high-frequency stimulation selectively impacts nigrostriatal dopaminergic neurons. Int. J. Neuropsychopharmacol., 17: 421-427.
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  38. Gill, K.M., J.M. Cook, M.M. Poe and A.A. Grace, 2014. Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia. Schizophrenia Bull., 40: 341-350.
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  39. Gill, K.M. and A.A. Grace, 2014. The role of α5 GABAA receptor agonists in the treatment of cognitive deficits in schizophrenia. Curr. Pharmaceut. Des., 20: 5069-5076.
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  40. Gill, K.M. and A.A. Grace, 2014. Corresponding decrease in neuronal markers signals progressive parvalbumin neuron loss in MAM schizophrenia model. Int. J. Neuropsychopharmacol., 17: 1609-1619.
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  41. Chang, C.H. and A.A. Grace, 2014. Amygdala-ventral pallidum pathway decreases dopamine activity after chronic mild stress in rats. Biol. Psychiatry, 76: 223-230.
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  42. Belujon, P. and A.A. Grace, 2014. Restoring mood balance in depression: Ketamine reverses deficit in dopamine-dependent synaptic plasticity. Biol. Psychiatry, 76: 927-936.
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  43. Zimmerman, E.C., M. Bellaire, S.G. Ewing and A.A. Grace, 2013. Abnormal stress responsivity in a rodent developmental disruption model of schizophrenia. Neuropsychopharmacology, 38: 2131-2139.
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  44. Sesia, T., B. Bizup and A.A. Grace, 2013. Evaluation of animal models of obsessive-compulsive disorder: Correlation with phasic dopamine neuron activity. Int. J. Neuropsychopharmacol., 16: 1295-1307.
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  45. Schlagenhauf, F., M.A. Rapp, Q.J. Huys, A. Beck and T. Wustenberg et al., 2013. Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence. Hum. Brain Mapping, 34: 1490-1499.
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  46. Savitz, J., C.A. Hodgkinson, C. Martin-Soelch, P.H. Shen and J. Szczepanik et al., 2013. The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement. PLoS ONE, Vol. 8. 10.1371/journal.pone.0054108.
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  47. Savitz, J., C.A. Hodgkinson, C. Martin-Soelch, P.H. Shen and J. Szczepanik et al., 2013. DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D2/3 receptor binding in healthy controls and patients with major depressive disorder. Int. J. Neuropsychopharmacol., 16: 2095-2101.
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  48. Patton, M.H., B.T. Bizup and A.A. Grace, 2013. The infralimbic cortex bidirectionally modulates mesolimbic dopamine neuron activity via distinct neural pathways. J. Neurosci., 33: 16865-16873.
    CrossRef  |  PubMed  |  Direct Link  |  
  49. McCracken, C.B. and A.A. Grace, 2013. Persistent cocaine-induced reversal learning deficits are associated with altered limbic cortico-striatal local field potential synchronization. J. Neurosci., 33: 17469-17482.
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  50. Lipski, W.J. and A.A. Grace, 2013. Footshock-induced responses in ventral subiculum neurons are mediated by locus coeruleus noradrenergic afferents. Eur. Neuropsychopharmacol., 23: 1320-1328.
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  51. Lipski, W.J. and A.A. Grace, 2013. Activation and inhibition of neurons in the hippocampal ventral subiculum by norepinephrine and locus coeruleus stimulation. Neuropsychopharmacology, 38: 285-292.
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  52. Ishikawa, M., M. Otaka, Y.H. Huang, P.A. Neumann and B.D. Winters et al., 2013. Dopamine triggers heterosynaptic plasticity. J. Neurosci., 33: 6759-6765.
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  53. Gill, K.M. and A.A. Grace, 2013. Differential effects of acute and repeated stress on hippocampus and amygdala inputs to the nucleus accumbens shell. Int. J. Neuropsychopharmacol., 16: 2013-2025.
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  54. Ewing, S.G., W.J. Lipski, A.A. Grace and C. Winter, 2013. An inexpensive, charge-balanced rodent deep brain stimulation device: A step-by-step guide to its procurement and construction. J. Neurosci. Methods, 219: 324-330.
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  55. Ewing, S.G., B. Porr, J. Riddell, C. Winter and A.A. Grace, 2013. SaBer DBS: A fully programmable, rechargeable, bilateral, charge-balanced preclinical microstimulator for long-term neural stimulation. J. Neurosci. Methods, 213: 228-235.
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  56. Ewing, S.G. and A.A. Grace, 2013. Long-term high frequency deep brain stimulation of the nucleus accumbens drives time-dependent changes in functional connectivity in the rodent limbic system. Brain Stimulation: Basic Transl. Clin. Res. Neuromodulation, 6: 274-285.
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  57. Ewing, S.G. and A.A. Grace, 2013. Evidence for impaired sound intensity processing during prepulse inhibition of the startle response in a rodent developmental disruption model of schizophrenia. J. Psychiatric Res., 47: 1630-1635.
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  58. Ewing, S.G. and A.A. Grace, 2013. Deep brain stimulation of the ventral hippocampus restores deficits in processing of auditory evoked potentials in a rodent developmental disruption model of schizophrenia. Schizophrenia Res., 143: 377-383.
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  59. Esmaeili, B. and A.A. Grace, 2013. Afferent drive of medial prefrontal cortex by hippocampus and amygdala is altered in MAM-treated rats: Evidence for interneuron dysfunction. Neuropsychopharmacology, 38: 1871-1880.
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  60. Du, Y. and A.A. Grace, 2013. Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia. Neuropsychopharmacology, 38: 1881-1888.
    CrossRef  |  Direct Link  |  
  61. Chang, C.H. and A.A. Grace, 2013. Some dopamine neurons may be more impulsive than others: Why differences in receptors and transporters can affect dopamine function in Parkinson's disease. Movement Disord., 28: 1319-1320.
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  62. Chang, C.H. and A.A. Grace, 2013. Amygdala β-noradrenergic receptors modulate delayed downregulation of dopamine activity following restraint. J. Neurosci., 33: 1441-1450.
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  63. Belujon, P., M.H. Patton and A.A. Grace, 2013. Disruption of prefrontal cortical-hippocampal balance in a developmental model of schizophrenia: Reversal by sulpiride. Int. J. Neuropsychopharmacol., 16: 507-512.
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  64. Belujon, P. and A.A. Grace, 2013. L-DOPA treatment duration versus Parkinson's disease progression: The dorsal-ventral divide. Mov. Disord., 28: 120-121.
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  65. Valenti, O., K.M. Gill and A.A. Grace, 2012. Different stressors produce excitation or inhibition of mesolimbic dopamine neuron activity: Response alteration by stress pre-exposure. Eur. J. Neurosci., 35: 1312-1321.
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  66. Ungless, M.A. and A.A. Grace, 2012. Are you or aren't you? Challenges associated with physiologically identifying dopamine neurons. Trends Neurosci., 35: 422-430.
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  67. Sesia, T. and A.A. Grace, 2012. Shifting pharmacology of nicotine use and withdrawal: Breaking the cycle of drug abuse. Proc. Natl. Acad. Sci. USA., 109: 2697-2698.
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  68. Moses-Kolko, E.L., J.C. Price, K.L. Wisner, B.H. Hanusa and C.C. Meltzer et al., 2012. Postpartum and depression status are associated with lower [11C] raclopride BPND in reproductive-age women. Neuropsychopharmacology, 37: 1422-1432.
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  69. Lodge, D.J. and A.A. Grace, 2012. Gestational methylazoxymethanol acetate administration alters proteomic and metabolomic markers of hippocampal glutamatergic transmission. Neuropsychopharmacology, 37: 319-320.
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  70. Lodge, D.J. and A.A. Grace, 2012. Divergent activation of ventromedial and ventrolateral dopamine systems in animal models of amphetamine sensitization and schizophrenia. Int. J. Neuropsychopharmacol., 15: 69-76.
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  71. Grace, A.A., 2012. Dopamine system dysregulation by the hippocampus: Implications for the pathophysiology and treatment of schizophrenia. Neuropharmacology, 62: 1342-1348.
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  72. Geerts, H., A. Spiros, P. Roberts, R. Twyman, L. Alphs and A.A. Grace, 2012. Blinded prospective evaluation of computer-based mechanistic schizophrenia disease model for predicting drug response. PLoS ONE, Vol. 7. 10.1371/journal.pone.0049732.
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  73. Cifelli, P. and A.A. Grace, 2012. Pilocarpine-induced temporal lobe epilepsy in the rat is associated with increased dopamine neuron activity. Int. J. Neuropsychopharmacol., 15: 957-964.
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  74. Belujon, P., M.H. Patton and A.A. Grace, 2012. Role of the prefrontal cortex in altered hippocampal-accumbens synaptic plasticity in a developmental animal model of schizophrenia. Cerebral Cortex, 24: 968-977.
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  75. Valenti, O., P. Cifelli, K.M. Gill and A.A. Grace, 2011. Antipsychotic drugs rapidly induce dopamine neuron depolarization block in a developmental rat model of schizophrenia. J. Neurosci., 31: 12330-12338.
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  76. Valenti, O., D.J. Lodge and A.A. Grace, 2011. Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus. J. Neurosci., 31: 4280-4289.
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  77. Lodge, D.J. and A.A. Grace, 2011. Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends Pharmacol. Sci., 32: 507-513.
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  78. Lodge, D.J. and A.A. Grace, 2011. Developmental pathology, dopamine, stress and schizophrenia. Int. J. Dev. Neurosci., 29: 207-213.
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  79. Lisman, J., A.A. Grace and E. Duzel, 2011. A neoHebbian framework for episodic memory; role of dopamine-dependent late LTP. Trends Neurosci., 34: 536-547.
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  80. Gill, K.M., D.J. Lodge, J.M. Cook, S. Aras and A.A. Grace, 2011. A novel α5GABAA R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia. Neuropsychopharmacology, 36: 1903-1911.
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  81. Gill, K.M. and A.A. Grace, 2011. Heterogeneous processing of amygdala and hippocampal inputs in the rostral and caudal subregions of the nucleus accumbens. Int. J. Neuropsychopharmacol., 14: 1301-1314.
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  82. Belujon, P. and A.A. Grace, 2011. Reorganization of striatal inhibitory microcircuits leads to pathological synchrony in the basal ganglia. Neuron, 71: 766-768.
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  83. Belujon, P. and A.A. Grace, 2011. Hippocampus, amygdala and stress: Interacting systems that affect susceptibility to addiction. Ann. N. Y. Acad. Sci., 1216: 114-121.
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  84. Valenti, O. and A.A. Grace, 2010. Antipsychotic drug-induced increases in ventral tegmental area dopamine neuron population activity via activation of the nucleus accumbens-ventral pallidum pathway. Int. J. Neuropsychopharmacol., 13: 845-860.
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  85. Sesack, S.R. and A.A. Grace, 2010. Cortico-basal ganglia reward network: Microcircuitry. Neuropsychopharmacology, 35: 27-47.
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  86. Grace, A.A., 2010. Ventral hippocampus, interneurons, and schizophrenia: A new understanding of the pathophysiology of schizophrenia and its implications for treatment and prevention. Curr. Directions Psychol. Sci., 19: 232-237.
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  87. Grace, A.A., 2010. Hippocampal dysregulation of dopamine system activity as a pathophysiological basis for psychosis in schizophrenia. Clin. Psychopharmacol. Neurosci., 8: 1-9.
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  88. Grace, A.A., 2010. Dopamine system dysregulation by the ventral subiculum as the common pathophysiological basis for schizophrenia psychosis, psychostimulant abuse and stress. Neurotoxicity Res., 18: 367-376.
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  89. Belujon, P., D.J. Lodge and A.A. Grace, 2010. Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatment. Mov. Disord., 25: 1568-1576.
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  90. McGinty, V.B. and A.A. Grace, 2009. Timing-dependent regulation of evoked spiking in nucleus accumbens neurons by integration of limbic and prefrontal cortical inputs. J. Neurophysiol., 101: 1823-1835.
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  91. McGinty, V.B. and A.A. Grace, 2009. Activity-dependent depression of medial prefrontal cortex inputs to accumbens neurons by the basolateral amygdala. Neuroscience, 162: 1429-1436.
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  92. McCracken, C.B. and A.A. Grace, 2009. Nucleus accumbens deep brain stimulation produces region-specific alterations in local field potential oscillations and evoked responses in vivo. J. Neurosci., 29: 5354-5363.
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  93. Lodge, D.J., M.M. Behrens and A.A. Grace, 2009. A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. J. Neurosci., 29: 2344-2354.
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  94. Lodge, D.J. and A.A. Grace, 2009. Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia. Behav. Brain Res., 204: 306-312.
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  95. Kumra, S., R. Asarnow, A. Grace, M. Keshavan, J. McClellan, L. Sikich and A. Wagner, 2009. From bench to bedside: Translating new research from genetics and neuroimaging into treatment development for early‐onset schizophrenia. Early Intervention Psychiatry, 3: 243-258.
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  96. Heinz, A., A.A. Grace and A. Beck, 2009. The intricacies of dopamine neuron modulation. Biol. Psychiatry, 65: 101-102.
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  97. Heinz, A., A. Beck, S.M. Grusser, A.A. Grace and J. Wrase, 2009. Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addict. Biol., 14: 108-118.
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  98. Buffalari, D.M. and A.A. Grace, 2009. Chronic cold stress increases excitatory effects of norepinephrine on spontaneous and evoked activity of basolateral amygdala neurons. Int. J. Neuropsychopharmacol., 12: 95-107.
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  99. Buffalari, D.M. and A.A. Grace, 2009. Anxiogenic modulation of spontaneous and evoked neuronal activity in the basolateral amygdala. Neuroscience, 163: 1069-1077.
    CrossRef  |  Direct Link  |  
  100. Wong, D.F., J.R. Brasic, H.S. Singer, D.J. Schretlen and H. Kuwabara et al., 2008. Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: Clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology, 33: 1239-1251.
    CrossRef  |  Direct Link  |  
  101. Valenti, O. and A.A. Grace, 2008. Entorhinal cortex inhibits medial prefrontal cortex and modulates the activity states of electrophysiologically characterized pyramidal neurons in vivo. Cerebral Cortex, 19: 658-674.
    CrossRef  |  Direct Link  |  
  102. Sengupta, S., N. Grizenko, N. Schmitz, G. Schwartz and J. Bellingham et al., 2008. COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHD. Neuropsychopharmacology, 33: 3069-3077.
    CrossRef  |  Direct Link  |  
  103. Onn, S.P., M. Lin, J.J. Liu and A.A. Grace, 2008. Dopamine and cyclic-AMP regulated phosphoprotein-32-dependent modulation of prefrontal cortical input and intercellular coupling in mouse accumbens spiny and aspiny neurons. Neuroscience, 151: 802-816.
    CrossRef  |  Direct Link  |  
  104. Lodge, D.J. and A.A. Grace, 2008. Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schizophrenia. Neurotoxicity Res., 14: 97-104.
    CrossRef  |  Direct Link  |  
  105. Lodge, D.J. and A.A. Grace, 2008. Amphetamine activation of hippocampal drive of mesolimbic dopamine neurons: A mechanism of behavioral sensitization. J. Neurosci., 28: 7876-7882.
    CrossRef  |  Direct Link  |  
  106. Lisman, J.E., J.T. Coyle, R.W. Green, D.C. Javitt, F.M. Benes, S. Heckers and A.A. Grace, 2008. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci., 31: 234-242.
    CrossRef  |  Direct Link  |  
  107. Krystal, J.H., C.S. Carter, D. Geschwind, H.K. Manji and J.S. March et al., 2008. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biol. Psychiatry, 63: 725-727.
    CrossRef  |  Direct Link  |  
  108. Jedema, H.P., S.J. Gold, G. Gonzalez-Burgos, A.F. Sved, B.J. Tobe, T.G. Wensel and A.A. Grace, 2008. Chronic cold exposure increases RGS7 expression and decreases α2-autoreceptor-mediated inhibition of noradrenergic locus coeruleus neurons. Eur. J. Neurosci., 27: 2433-2443.
    CrossRef  |  Direct Link  |  
  109. Grace, A.A., 2008. Physiology of the normal and dopamine-depleted basal ganglia: Insights into levodopa pharmacotherapy. Mov. Disord., 23: S560-S569.
    CrossRef  |  Direct Link  |  
  110. Goto, Y. and A.A. Grace, 2008. Limbic and cortical information processing in the nucleus accumbens. Trends Neurosci., 31: 552-558.
    CrossRef  |  Direct Link  |  
  111. Bissiere, S., N. Plachta, D. Hoyer, K.H. McAllister, H.R. Olpe, A.A. Grace and J.F. Cryan, 2008. The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning. Biol. Psychiatry, 63: 821-831.
    CrossRef  |  Direct Link  |  
  112. Belujon, P. and A.A. Grace, 2008. Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow. J. Neurosci., 28: 9797-9805.
    CrossRef  |  Direct Link  |  
  113. McGinty, V.B. and A.A. Grace, 2007. Selective activation of medial prefrontal-to-accumbens projection neurons by amygdala stimulation and Pavlovian conditioned stimuli. Cerebral Cortex, 18: 1961-1972.
    CrossRef  |  Direct Link  |  
  114. McCracken, C.B. and A.A. Grace, 2007. High-frequency deep brain stimulation of the nucleus accumbens region suppresses neuronal activity and selectively modulates afferent drive in rat orbitofrontal cortex in vivo. J. Neurosci., 27: 12601-12610.
    CrossRef  |  Direct Link  |  
  115. Lodge, D.J. and A.A. Grace, 2007. Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. J. Neurosci., 27: 11424-11430.
    CrossRef  |  Direct Link  |  
  116. Grace, A.A., S.B. Floresco, Y. Goto and D.J. Lodge, 2007. Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends Neurosci., 30: 220-227.
    CrossRef  |  Direct Link  |  
  117. Grace, A.A., 2007. Stress-Induced Pathophysiology within the Schizophrenia Patient Brain: A Model for the Delayed Onset of Psychosis and its Circumvention by Anxiolytic Agents. In: Adolescent Brain and Psychopathology: Integrating Brain and Prevention Science, Romer, D. and E.F. Walker (Eds.). Oxford University Press, Oxford, UK., pp: 245-263.
  118. Goto, Y., S. Otani and A.A. Grace, 2007. The Yin and Yang of dopamine release: A new perspective. Neuropharmacology, 53: 583-587.
    CrossRef  |  Direct Link  |  
  119. Goto, Y. and A.A. Grace, 2007. The dopamine system and the pathophysiology of schizophrenia: A basic science perspective. Int. Rev. Neurobiol., 78: 41-68.
    CrossRef  |  Direct Link  |  
  120. Goto, Y. and A.A. Grace, 2007. Dopamine modulation of hippocampal-prefrontal cortical interaction drives memory-guided behavior. Cerebral Cortex, 18: 1407-1414.
    CrossRef  |  Direct Link  |  
  121. Buffalari, D.M. and A.A. Grace, 2007. Noradrenergic modulation of basolateral amygdala neuronal activity: Opposing influences of α-2 and β receptor activation. J. Neurosci., 27: 12358-12366.
    CrossRef  |  PubMed  |  Direct Link  |  
  122. Agid, Y., G. Buzsaki, D.M. Diamond, R. Frackowiak and J. Giedd et al., 2007. How can drug discovery for psychiatric disorders be improved? Nat. Rev. Drug Discov., 6: 189-201.
    CrossRef  |  Direct Link  |  
  123. Wong, D.F., H. Kuwabara, D.J. Schretlen, K.R. Bonson and Y. Zhou et al., 2006. Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology, 31: 2716-2727.
    CrossRef  |  Direct Link  |  
  124. Rosenkranz, J.A., D.M. Buffalari and A.A. Grace, 2006. Opposing influence of basolateral amygdala and footshock stimulation on neurons of the central amygdala. Biol. Psychiatry, 59: 801-811.
    CrossRef  |  Direct Link  |  
  125. Onn, S.P., X.B. Wang, M. Lin and A.A. Grace, 2006. Dopamine D1 and D4 receptor subtypes differentially modulate recurrent excitatory synapses in prefrontal cortical pyramidal neurons. Neuropsychopharmacology, 31: 318-338.
    CrossRef  |  Direct Link  |  
  126. Moore, H., J.D. Jentsch, M. Ghajarnia, M.A. Geyer and A.A. Grace, 2006. A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: Implications for the neuropathology of schizophrenia. Biol. Psychiatry, 60: 253-264.
    CrossRef  |  Direct Link  |  
  127. Miner, L.H., H.P. Jedema, F.W. Moore, R.D. Blakely, A.A. Grace and S.R. Sesack, 2006. Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex. J. Neurosci., 26: 1571-1578.
    CrossRef  |  Direct Link  |  
  128. Lodge, D.J. and A.A. Grace, 2006. The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons. Proc. Natl. Acad. Sci. USA., 103: 5167-5172.
    CrossRef  |  Direct Link  |  
  129. Lodge, D.J. and A.A. Grace, 2006. The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation. Neuropsychopharmacology, 31: 1356-1361.
    CrossRef  |  Direct Link  |  
  130. Laviolette, S.R. and A.A. Grace, 2006. The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: Implications for schizophrenia and addiction. Cell. Mol. Life Sci., 63: 1597-1613.
    CrossRef  |  Direct Link  |  
  131. Laviolette, S.R. and A.A. Grace, 2006. Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs. J. Neurosci., 26: 6458-6468.
    CrossRef  |  Direct Link  |  
  132. Kawashima, H., Y. Izaki, A.A. Grace and M. Takita, 2006. Cooperativity between hippocampal-prefrontal short-term plasticity through associative long-term potentiation. Brain Res., 1109: 37-44.
    CrossRef  |  Direct Link  |  
  133. Grace, A.A., 2006. Disruption of cortical-limbic interaction as a substrate for comorbidity. Neurotoxicity Res., 10: 93-101.
    CrossRef  |  Direct Link  |  
  134. Goto, Y. and A.A. Grace, 2006. Alterations in medial prefrontal cortical activity and plasticity in rats with disruption of cortical development. Biol. Psychiatry, 60: 1259-1267.
    CrossRef  |  Direct Link  |  
  135. Lodge, D.J. and A.A. Grace, 2005. Acute and chronic corticotropin-releasing factor 1 receptor blockade inhibits cocaine-induced dopamine release: Correlation with dopamine neuron activity. J. Pharmacol. Exp. Therapeut., 314: 201-206.
    CrossRef  |  Direct Link  |  
  136. Lisman, J.E. and A.A. Grace, 2005. The hippocampal-VTA loop: Controlling the entry of information into long-term memory. Neuron, 46: 703-713.
    CrossRef  |  
  137. Laviolette, S.R., W.J. Lipski and A.A. Grace, 2005. A subpopulation of neurons in the medial prefrontal cortex encodes emotional learning with burst and frequency codes through a dopamine D4 receptor-dependent basolateral amygdala input. J. Neurosci., 25: 6066-6075.
    CrossRef  |  Direct Link  |  
  138. Lavin, A., H.M. Moore and A.A. Grace, 2005. Prenatal disruption of neocortical development alters prefrontal cortical neuron responses to dopamine in adult rats. Neuropsychopharmacology, 30: 1426-1435.
    CrossRef  |  Direct Link  |  
  139. Kroner, S., J.A. Rosenkranz, A.A. Grace and G. Barrionuevo, 2005. Dopamine modulates excitability of basolateral amygdala neurons in vitro. J. Neurophysiol., 93: 1598-1610.
    CrossRef  |  Direct Link  |  
  140. Goto, Y. and A.A. Grace, 2005. Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior. Nat. Neurosci., 8: 805-812.
    CrossRef  |  Direct Link  |  
  141. Goto, Y. and A.A. Grace, 2005. Dopamine-dependent interactions between limbic and prefrontal cortical plasticity in the nucleus accumbens: Disruption by cocaine sensitization. Neuron, 47: 255-266.
    CrossRef  |  Direct Link  |  
  142. Floresco, S.B., M.A. Geyer, L.H. Gold and A.A. Grace, 2005. Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia. Schizophrenia Bull., 31: 888-894.
    CrossRef  |  Direct Link  |  
  143. Correll, C.M., J.A. Rosenkranz and A.A. Grace, 2005. Chronic cold stress alters prefrontal cortical modulation of amygdala neuronal activity in rats. Biol. Psychiatry, 58: 382-391.
    CrossRef  |  Direct Link  |  
  144. West, A.R. and A.A. Grace, 2004. The nitric oxide-guanylyl cyclase signaling pathway modulates membrane activity states and electrophysiological properties of striatal medium spiny neurons recorded in vivo. J. Neurosci., 24: 1924-1935.
    CrossRef  |  Direct Link  |  
  145. Thompson, J.L., M.F. Pogue-Geile and A.A. Grace, 2004. Developmental pathology, dopamine and stress: A model for the age of onset of schizophrenia symptoms. Schizophrenia Bull., 30: 875-900.
    PubMed  |  Direct Link  |  
  146. Jedema, H.P. and A.A. Grace, 2004. Corticotropin-releasing hormone directly activates noradrenergic neurons of the locus ceruleus recorded in vitro. J. Neurosci., 24: 9703-9713.
    CrossRef  |  Direct Link  |  
  147. Grace, A.A., 2004. Schizophrenia Represents a Failure to Regulate Dopamine Systems. In: Schizophrenia-Challenging the Orthodox, McDonald, C., K. Schulze, R.M. Murray and P. Wright (Eds.). Martin Dunitz Publishers, London, UK., pp: 137-144.
  148. Grace, A.A., 2004. Developmental Dysregulation of the Dopamine System and the Pathophysiology of Schizophrenia. In: Neurodevelopment and Schizophrenia, Keshavan, M., J.L. Kennedy and R.M. Murray (Eds.). Cambridge University Press, Cambridge, UK., pp: 273-294.
  149. Fiore, M., A.A. Grace, J. Korf, B. Stampachiacchiere and L. Aloe, 2004. Impaired brain development in the rat following prenatal exposure to methylazoxymethanol acetate at gestational day 17 and neurotrophin distribution. Neuroreport, 15: 1791-1795.
    CrossRef  |  Direct Link  |  
  150. Bilder, R.M., J. Volavka, H.M. Lachman and A.A. Grace, 2004. The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology, 29: 1943-1961.
    CrossRef  |  Direct Link  |  
  151. Rosenkranz, J.A., H. Moore and A.A. Grace, 2003. The prefrontal cortex regulates lateral amygdala neuronal plasticity and responses to previously conditioned stimuli. J. Neurosci., 23: 11054-11064.
    CrossRef  |  Direct Link  |  
  152. Rosenkranz, J.A. and A.A. Grace, 2003. Affective conditioning in the basolateral amygdala of anesthetized rats is modulated by dopamine and prefrontal cortical inputs. Ann. N. Y. Acad. Sci., 985: 488-491.
    CrossRef  |  Direct Link  |  
  153. Onn, S.P., A.A. Fienberg and A.A. Grace, 2003. Dopamine modulation of membrane excitability in striatal spiny neurons is altered in DARPP-32 knockout mice. J. Pharmacol. Exp. Therapeut., 306: 870-879.
    CrossRef  |  Direct Link  |  
  154. Jedema, H.P. and A.A. Grace, 2003. Chronic exposure to cold stress alters electrophysiological properties of locus coeruleus neurons recorded in vitro. Neuropsychopharmacology, 28: 63-72.
    CrossRef  |  Direct Link  |  
  155. Grace, A.A., 2003. Gating within limbic-cortical circuits and its alteration in a developmental disruption model of schizophrenia. Clin. Neurosci. Res., 3: 333-338.
    CrossRef  |  Direct Link  |  
  156. Grace, A., 2003. Forebrain dopamine systems-can they help us to understand psychosis? Eur. Psychiatry, 18: 27s-31s.
    CrossRef  |  Direct Link  |  
  157. Floresco, S.B., A.R. West, B. Ash, H. Moore and A.A. Grace, 2003. Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nat. Neurosci., 6: 968-973.
    CrossRef  |  Direct Link  |  
  158. Floresco, S.B. and A.A. Grace, 2003. Gating of hippocampal-evoked activity in prefrontal cortical neurons by inputs from the mediodorsal thalamus and ventral tegmental area. J. Neurosci., 23: 3930-3943.
    CrossRef  |  Direct Link  |  
  159. Charara, A. and A.A. Grace, 2003. Dopamine receptor subtypes selectively modulate excitatory afferents from the hippocampus and amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology, 28: 1412-1421.
    CrossRef  |  Direct Link  |  
  160. West, A.R., M.P. Galloway and A.A. Grace, 2002. Regulation of striatal dopamine neurotransmission by nitric oxide: Effector pathways and signaling mechanisms. Synapse, 44: 227-245.
    CrossRef  |  Direct Link  |  
  161. West, A.R., H. Moore and A.A. Grace, 2002. Direct examination of local regulation of membrane activity in striatal and prefrontal cortical neurons in vivo using simultaneous intracellular recording and microdialysis. J. Pharmacol. Exp. Therapeut., 301: 867-877.
    CrossRef  |  Direct Link  |  
  162. West, A.R. and A.A. Grace, 2002. Opposite influences of endogenous dopamine D1 and D2 receptor activation on activity states and electrophysiological properties of striatal neurons: Studies combining in vivo intracellular recordings and reverse microdialysis. J. Neurosci., 22: 294-304.
    CrossRef  |  Direct Link  |  
  163. Singer, H.S., S. Szymanski, J. Giuliano, F. Yokoi and A.S. Dogan et al., 2002. Elevated intrasynaptic dopamine release in Tourette's syndrome measured by PET. Am. J. Psychiatry, 159: 1329-1336.
    CrossRef  |  Direct Link  |  
  164. Rosenkranz, J.A. and A.A. Grace, 2002. Dopamine-mediated modulation of odour-evoked amygdala potentials during pavlovian conditioning. Nature, 417: 282-287.
    CrossRef  |  Direct Link  |  
  165. Rosenkranz, J.A. and A.A. Grace, 2002. Cellular mechanisms of infralimbic and prelimbic prefrontal cortical inhibition and dopaminergic modulation of basolateral amygdala neurons in vivo. J. Neurosci., 22: 324-337.
    CrossRef  |  Direct Link  |  
  166. Moore, H. and A.A. Grace, 2002. A role for electrotonic coupling in the striatum in the expression of dopamine receptor-mediated stereotypies. Neuropsychopharmacology, 27: 980-992.
    CrossRef  |  Direct Link  |  
  167. Grace, A.A., 2002. Dopamine. In: Neuropsychopharmacology: The Fifth Generation of Progress, Charney, D., J. Coyle, K. Davis and C. Nemeroff (Eds.). Lippincott, Williams and Wilkins, New York, USA., pp: 119-132.
  168. Grace, A.A. and J.A. Rosenkranz, 2002. Regulation of conditioned responses of basolateral amygdala neurons. Physiol. Behav., 77: 489-493.
    CrossRef  |  Direct Link  |  
  169. West, A.R. and A.A. Grace, 2001. The Role of Frontal-Subcortical Circuits in the Pathophysiology of Schizophrenia. In: Frontal-Subcortical Circuits in Neurology and Psychiatry, Lichter, D.G. (Ed.). Guilford Press, New York, USA., pp: 372-400.
  170. Turner, M.S., A. Lavin, A.A. Grace and T.C. Napier, 2001. Regulation of limbic information outflow by the subthalamic nucleus: Excitatory amino acid projections to the ventral pallidum. J. Neurosci., 21: 2820-2832.
    CrossRef  |  Direct Link  |  
  171. Rosenkranz, J.A. and A.A. Grace, 2001. Dopamine attenuates prefrontal cortical suppression of sensory inputs to the basolateral amygdala of rats. J. Neurosci., 21: 4090-4103.
    CrossRef  |  Direct Link  |  
  172. Moore, H., H.J. Rose and A.A. Grace, 2001. Chronic cold stress reduces the spontaneous activity of ventral tegmental dopamine neurons. Neuropsychopharmacology, 24: 410-419.
    CrossRef  |  Direct Link  |  
  173. Lavin, A. and A.A. Grace, 2001. Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. Neuroscience, 104: 335-346.
    CrossRef  |  Direct Link  |  
  174. Jedema, H.P., J.M. Finlay, A.F. Sved and A.A. Grace, 2001. Chronic cold exposure potentiates CRH-evoked increases in electrophysiologic activity of locus coeruleus neurons. Biol. Psychiatry, 49: 351-359.
    CrossRef  |  Direct Link  |  
  175. Grace, A.A., 2001. Psychostimulant Actions on Dopamine and Limbic System Function: Relevance to the Pathophysiology and Treatment of ADHD. In: Stimulant Drugs and ADHD: Basic and Clinical Neuroscience, Solanto, M.V., A.F.T. Arnsten and F.X. Castellanos (Eds.). Oxford University Press, New York, USA., pp: 134-157.
  176. Floresco, S.B., C.L. Todd and A.A. Grace, 2001. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. J. Neurosci., 21: 4915-4922.
    CrossRef  |  Direct Link  |  
  177. Drevets, W.C., C. Gautier, J.C. Price, D.J. Kupfer and P.E. Kinahan et al., 2001. Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biol. Psychiatry, 49: 81-96.
    CrossRef  |  Direct Link  |  
  178. West, A.R. and A.A. Grace, 2000. Striatal nitric oxide signaling regulates the neuronal activity of midbrain dopamine neurons in vivo. J. Neurophysiol., 83: 1796-1808.
    CrossRef  |  Direct Link  |  
  179. Onn, S.P., A.R. West and A.A. Grace, 2000. Dopamine-mediated regulation of striatal neuronal and network interactions. Trends Neurosci., 23: S48-S56.
    CrossRef  |  Direct Link  |  
  180. Onn, S.P. and A.A. Grace, 2000. Amphetamine withdrawal alters bistable states and cellular coupling in rat prefrontal cortex and nucleus accumbens neurons recorded in vivo. J. Neurosci., 20: 2332-2345.
    CrossRef  |  Direct Link  |  
  181. Grace, A.A., 2000. The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving. Addiction, 95: 119-128.
    CrossRef  |  Direct Link  |  
  182. Grace, A.A., 2000. Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Brain Res. Rev., 31: 330-341.
    CrossRef  |  Direct Link  |  
  183. Todd, C.L. and A.A. Grace, 1999. Modulation of ventral tegmental area dopamine cell activity by the ventral subiculum and entorhinal cortex. Ann. N. Y. Acad. Sci., 877: 688-690.
    CrossRef  |  Direct Link  |  
  184. Todd, C.L. and A.A. Grace, 1999. Interaction of benztropine and haloperidol actions on rat substantia nigra dopamine cell electrophysiological activity in vivo. Brain Res. Bull., 48: 219-222.
    CrossRef  |  Direct Link  |  
  185. Rosenkranz, J.A. and A.A. Grace, 1999. Modulation of basolateral amygdala neuronal firing and afferent drive by dopamine receptor activation in vivo. J. Neurosci., 19: 11027-11039.
    CrossRef  |  Direct Link  |  
  186. O’Donnell, P., J. Green, N. Pabello, B.L. Lewis and A.A. Grace, 1999. Modulation of cell firing in the nucleus accumbens. Ann. N. Y. Acad. Sci., 877: 157-175.
    CrossRef  |  Direct Link  |  
  187. O’Donnell, P. and A.A. Grace, 1999. Disruption of Information Flow within Cortical-Limbic Circuits and the Pathophysiology of Schizophrenia. In: Schizophrenia in a Molecular Age, Tamminga, C.A. (Ed.). American Psychiatric Press, Washington, DC., pp: 109-140.
  188. Onn, S.P. and A.A. Grace, 1999. Alterations in electrophysiological activity and dye coupling of striatal spiny and aspiny neurons in dopamine‐denervated rat striatum recorded in vivo. Synapse, 33: 1-15.
    CrossRef  |  Direct Link  |  
  189. Newman, J. and A.A. Grace, 1999. Binding across time: The selective gating of frontal and hippocampal systems modulating working memory and attentional states. Consciousness Cognition, 8: 196-212.
    CrossRef  |  Direct Link  |  
  190. Moore, H., A.R. West and A.A. Grace, 1999. The regulation of forebrain dopamine transmission: Relevance to the pathophysiology and psychopathology of schizophrenia. Biol. Psychiatry, 46: 40-55.
    CrossRef  |  Direct Link  |  
  191. O’Donnell, P. and A.A. Grace, 1998. Phencyclidine interferes with the hippocampal gating of nucleus accumbens neuronal activity in vivo. Neuroscience, 87: 823-830.
    CrossRef  |  Direct Link  |  
  192. O’Donnell, P. and A.A. Grace, 1998. Dysfunctions in multiple interrelated systems as the neurobiological bases of schizophrenic symptom clusters. Schizophrenia Bull., 24: 267-283.
    CrossRef  |  Direct Link  |  
  193. Moore, H., C.L. Todd and A.A. Grace, 1998. Striatal extracellular dopamine levels in rats with haloperidol-induced depolarization block of substantia nigra dopamine neurons. J. Neurosci., 18: 5068-5077.
    CrossRef  |  Direct Link  |  
  194. Lavin, A. and A.A. Grace, 1998. Response of the ventral pallidal/mediodorsal thalamic system to antipsychotic drug administration: Involvement of the prefrontal cortex. Neuropsychopharmacology, 18: 352-363.
    CrossRef  |  Direct Link  |  
  195. Lavin, A. and A.A. Grace, 1998. Dopamine modulates the responsivity of mediodorsal thalamic cells recorded in vitro. J. Neurosci., 18: 10566-10578.
    CrossRef  |  Direct Link  |  
  196. Harden, D.G., D. King, J. Finlay and A.A. Grace, 1998. Depletion of dopamine in the prefrontal cortex decreases the basal electrophysiological activity of mesolimbic dopamine neurons. Brain Res., 794: 96-102.
    CrossRef  |  Direct Link  |  
  197. Grace, A.A. and H. Moore, 1998. Regulation of Information Flow in the Nucleus Accumbens: A Model for the Pathophysiology of Schizophrenia. In: Origins and Development of Schizophrenia: Advances in Experimental Psychopathology, Lenzenweger, M.F. and R.H. Dworkin (Eds.). American Psychological Association Press, Washington, DC., pp: 123-157.
  198. Grace, A.A. and B.S. Bunney, 1998. Electrophysiology. In: American Psychiatric Press Textbook of Psychopharmacology, Nemeroff, C.B. and A.F. Schatzberg (Eds.). 2nd Edn., American Psychiatric Press, Washington, DC., pp: 75-88.
  199. Fienberg, A.A., N. Hiroi, P. Mermelstein, W.J. Song and G.L. Snyder et al., 1998. DARPP-32, regulator of the efficacy of dopaminergic transmission. Science, 281: 838-842.
  200. Czernansky, J.G. and A.A. Grace, 1998. New pathophysiological models of schizophrenia. Schizophrenia Bull., 24: 185-316.
  201. Czernansky, J.G. and A.A. Grace, 1998. New models of the pathophysiology of schizophrenia: Editors’ introduction. Schizophrenia Bull., 24: 185-187.
  202. O’Donnell, P., A. Lavin, L.W. Enquist, A.A. Grace and J.P. Card, 1997. Interconnected parallel circuits between rat nucleus accumbens and thalamus revealed by retrograde transynaptic transport of pseudorabies virus. J. Neurosci., 17: 2143-2167.
  203. Mana, M.J. and A.A. Grace, 1997. Chronic cold stress alters the basal and evoked electrophysiological activity of rat locus coeruleus neurons. Neuroscience, 81: 1055-1064.
    CrossRef  |  Direct Link  |  
  204. Grace, A.A., H. Moore and P. O’Donnell, 1997. The modulation of corticoaccumbens transmission by limbic afferents and dopamine: A model for the pathophysiology of schizophrenia. Adv. Pharmacol., 42: 721-724.
    CrossRef  |  Direct Link  |  
  205. Grace, A.A., C.R. Gerfen and G. Aston-Jones, 1997. Theme F: Catecholamines in the central nervous system: Overview. Adv. Pharmacol., 42: 655-670.
  206. Grace, A.A., C.L. Todd and H. Moore, 1997. Glutamatergic effects and depolarization block-Reply. Trends Neurosci., 20: 394-395.
  207. Grace, A.A., B.S. Bunney, H. Moore and C.L. Todd, 1997. Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends Neurosci., 20: 31-37.
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  208. Pucak, M.L. and A.A. Grace, 1996. Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. Brain Res., 713: 44-52.
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  209. O’Donnell, P. and A.A. Grace, 1996. Dopaminergic reduction of excitability in nucleus accumbens neurons recorded in vitro. Neuropsychopharmacology, 15: 87-97.
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  210. O’Donnell, P. and A.A. Grace, 1996. Cortical afferents modulate striatal gap junction permeability via nitric oxide. Neuroscience, 76: 1-5.
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  211. O’Donnell, P. and A.A. Grace, 1996. Basic Neurophysiology of Antipsychotic Drug Action. In: Handbook of Experimental Pharmacology: Antipsychotics, Csernansky, J.G. (Ed.). Springer-Verlag, Heidelberg, pp: 163-202.
  212. Lavin, A. and A.A. Grace, 1996. Physiological properties of rat ventral pallidal neurons recorded intracellularly in vivo. J. Neurophysiol., 75: 1432-1443.
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  213. Grace, A.A., 1996. Gating of Information Flow through Limbic and Thalamocortical Systems: Implications for the Pathophysiology of Schizophrenia. In: Schizophrenia: Latest Advances in Understanding and Drug Development, Dirks, L. (Ed.). IBC Biomedical Library, Southborough, MA., pp: 1.3.1.
    CrossRef  |  
  214. Onn, S.P. and A.A. Grace, 1995. Repeated treatment with haloperidol and clozapine exerts differential effects on dye coupling between neurons in subregions of striatum and nucleus accumbens. J. Neurosci., 15: 7024-7036.
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  215. O'Donnell, P. and A.A. Grace, 1995. Synaptic interactions among excitatory afferents to nucleus accumbens neurons: Hippocampal gating of prefrontal cortical input. J. Neurosci., 15: 3622-3639.
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  216. O'Donnell, P. and A.A. Grace, 1995. Different effects of subchronic clozapine and haloperidol on dye-coupling between neurons in the rat striatal complex. Neuroscience, 66: 763-767.
    CrossRef  |  Direct Link  |  
  217. Harden, D.G. and A.A. Grace, 1995. Activation of dopamine cell firing by repeated L-DOPA administration to dopamine-depleted rats: Its potential role in mediating the therapeutic response to L-DOPA treatment. J. Neurosci., 15: 6157-6166.
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  218. Grace, A.A., 1995. The tonic/phasic model of dopamine system regulation: Its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug Alcohol Dependence, 37: 111-129.
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  219. Grace, A.A. and B.S. Bunney, 1995. Electrophysiology. In: American Psychiatric Press Textbook of Psychopharmacology, Nemeroff, C.B. and A.F. Schatzberg (Eds.). American Psychiatric Press, Washington, DC., pp: 65-79.
  220. Grace, A.A. and B.S. Bunney, 1995. Electrophysiological Properties of Midbrain Dopamine Neurons. In: Psychopharmacology: The Fourth Generation of Progress, Bloom, F.E. and D.J. Kupfer (Eds.). Raven Press, New York, pp: 163-177.
  221. Pucak, M.L. and A.A. Grace, 1994. The regulation of substantia nigra dopamine neurons. Crit. Rev. Neurobiol., 9: 67-89.
  222. Pucak, M.L. and A.A. Grace, 1994. Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors. J. Pharmacol. Exp. Ther., 371: 1181-1192.
    Direct Link  |  
  223. Onn, S.P., T.W. Berger and A.A. Grace, 1994. Identification and characterization of striatal cell subtypes using in vivo intracellular recording in rats: II. Membrane factors underlying paired‐pulse response profiles. Synapse, 16: 195-210.
    CrossRef  |  Direct Link  |  
  224. Onn, S.P., T.W. Berger and A.A. Grace, 1994. Identification and characterization of striatal cell subtypes using in vivo intracellular recording in rats. I. Basic physiology and response to corticostriatal fiber stimulation. Synapse, 16: 161-180.
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  225. Onn, S.P., T.W. Berger and A.A. Grace, 1994. Identification and characterization of striatal cell subtypes using in vivo intracellular recording and dye‐labeling in rats. III. Morphological correlates and compartmental localization. Synapse, 16: 231-254.
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  226. Onn, S.P. and A.A. Grace, 1994. Dye coupling between rat striatal neurons recorded in vivo: Compartmental organization and modulation by dopamine. J. Neurophysiol., 71: 1917-1934.
    CrossRef  |  Direct Link  |  
  227. O'Donnell, P. and A.A. Grace, 1994. Tonic D2-mediated attenuation of cortical excitation in nucleus accumbens neurons recorded in vitro. Brain Res., 634: 105-112.
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  228. Lavin, A. and A.A. Grace, 1994. Modulation of dorsal thalamic cell activity by the ventral pallidum: Its role in the regulation of thalamocortical activity by the basal ganglia. Synapse, 18: 104-127.
    CrossRef  |  Direct Link  |  
  229. Zigmond, M.J., E.D. Abercrombie, T.W. Berger, A.A. Grace and E.M. Stricker, 1993. Compensatory Responses to Partial Loss of Dopaminergic Neurons: Studies with 6-Hydroxydopamine. In: Current Concepts in Parkinson's Disease Research, Schneider, J.S. and M. Gupta (Eds.). Hogrefe and Huber Publishers, Toronto, pp: 99-140.
  230. Onn, S.P., M.L. Pucak and A.A. Grace, 1993. Lucifer yellow dye labeling of living nerve cells and subsequent immunoperoxidase staining with Lucifer yellow antiserum. Neurosci. Protocols, 90: 153-160.
  231. O'Donnell, P. and A.A. Grace, 1993. Physiological and morphological properties of accumbens core and shell neurons recorded in vitro. Synapse, 13: 135-160.
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  232. Nisenbaum, E.S., T.W. Berger and A.A. Grace, 1993. Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors. Synapse, 14: 221-242.
    CrossRef  |  Direct Link  |  
  233. Grace, A.A., 1993. Cortical regulation of subcortical dopamine systems and its possible relevance to schizophrenia. J. Neural Transm., 91: 111-134.
    CrossRef  |  Direct Link  |  
  234. Smith, I.D. and A.A. Grace, 1992. Role of the subthalamic nucleus in the regulation of nigral dopamine neuron activity. Synapse, 12: 287-303.
    CrossRef  |  Direct Link  |  
  235. Nisenbaum, E.S., T.W. Berger and A.A. Grace, 1992. Presynaptic modulation by GABAB receptors of glutamatergic excitation and GABAergic inhibition of neostriatal neurons. J. Neurophysiol., 67: 477-481.
    CrossRef  |  Direct Link  |  
  236. Nisenbaum, E.S., A.A. Grace and T.W. Berger, 1992. Functionally distinct subpopulations of striatal neurons are differentially regulated by GABAergic and dopaminergic inputs. II. In vitro analysis. Neuroscience, 48: 579-593.
  237. Hollerman, J.R., E.D. Abercrombie and A.A. Grace, 1992. Electrophysiological, biochemical and behavioral studies of acute haloperidol-induced depolarization block of nigral dopamine neurons. Neuroscience, 47: 589-601.
    CrossRef  |  Direct Link  |  
  238. Hollerman, J.R. and A.A. Grace, 1992. Subthalamic nucleus cell firing in the 6-OHDA-treated rat: Basal activity and response to haloperidol. Brain Res., 590: 291-299.
    CrossRef  |  Direct Link  |  
  239. Grace, A.A., 1992. The depolarization block hypothesis of neuroleptic action: Implications for the etiology and treatment of schizophrenia. J. Neural Transm., 36: 91-131.
    CrossRef  |  Direct Link  |  
  240. Smith, I.D. and A.A. Grace, 1991. Subthalamic nucleus afferents to the substantia nigra regulate dopamine neuron burst firing. Posters Neurosci., 1: 25-28.
  241. Pucak, M.L. and A.A. Grace, 1991. Partial dopamine depletions result in an enhanced sensitivity of residual dopamine neurons to apomorphine. Synapse, 9: 144-155.
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  242. Nisenbaum, E.S., A.A. Grace and T.W. Berger, 1991. Differential contribution of D1 and D2 dopaminergic receptors to the response properties of two functionally distinct subpopulations of striatal neurons. Posters Neurosci., 1: 59-66.
  243. Llinas, R.R., A.A. Grace and Y. Yarom, 1991. In vitro neurons in mammalian cortical layer 4 exhibit intrinsic oscillatory activity in the 10-to 50-Hz frequency range. Proc. Natl. Acad. Sci., 88: 897-901.
    CrossRef  |  Direct Link  |  
  244. Grace, A.A., 1991. The modulation of dopamine system responsivity by cortically regulated extracellular dopamine levels: A hypothesis for the etiology of schizophrenia. Posters Neurosci., 1: 3-8.
  245. Grace, A.A., 1991. Regulation of spontaneous activity and oscillatory spike firing in rat midbrain dopamine neurons recorded in vitro. Synapse, 7: 221-234.
    CrossRef  |  Direct Link  |  
  246. Grace, A.A., 1991. Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neuroscience, 41: 1-24.
  247. Bunney, B.S., L.A. Chiodo and A.A. Grace, 1991. Midbrain dopamine system electrophysiological functioning: A review and new hypothesis. Synapse, 9: 79-94.
    CrossRef  |  Direct Link  |  
  248. Zigmond, M.J., E.D. Abercrombie, T.W. Berger, A.A. Grace and E.M. Stricker, 1990. Compensations after lesions of central dopaminergic neurons: Some clinical and basic implications. Trends Neurosci., 13: 290-296.
    CrossRef  |  Direct Link  |  
  249. Hollerman, J.R. and A.A. Grace, 1990. The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. Brain Res., 533: 203-212.
    CrossRef  |  Direct Link  |  
  250. Grace, A.A., 1990. Evidence for the functional compartmentalization of spike generating regions of rat mdbrain dopamine neurons recorded in vitro. Brain Res., 524: 31-41.
    CrossRef  |  Direct Link  |  
  251. Berger, T.W., E.S. Nisenbaum, S.P. Onn and A.A. Grace, 1990. Pharmacological and Morphological Properties of Two Functionally Distinct Subpopulations of Striatal Neurons. In: The Basal Ganglia III, Bernardi, G., M.B. Carpenter, G. DiChiara, M. Morelli and P. Stanzione (Eds.). Plenum Press, New York, ISBN: 978-1-4684-5871-8, pp: 335-345.
  252. Zigmond, M.J., T.W. Berger, A.A. Grace and E.M. Stricker, 1989. Compensatory responses to nigrostriatal bundle injury: Studies with 6-hydroxydopamine in an animal model of Parkinsonism. Mol. Chem. Neuropathol., 10: 185-200.
    CrossRef  |  Direct Link  |  
  253. Hollerman, J.R. and A.A. Grace, 1989. Acute haloperidol administration induces depolarization block of nigral dopamine neurons in rats after partial dopamine lesions. Neurosci. Lett., 96: 82-88.
    CrossRef  |  Direct Link  |  
  254. Grace, A.A. and S.P. Onn, 1989. Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. J. Neurosci., 9: 3463-3481.
    Direct Link  |  
  255. Grace, A.A., 1988. In vivo and in vitro intracellular recordings from rat midbrain dopamine neurons. Ann. N. Y. Acad. Sci., 537: 51-76.
    CrossRef  |  Direct Link  |  
  256. Grace, A.A., 1987. The Regulation of Dopamine Neuron Activity as Determined by In vivo and In vitro Intracellular Recordings. In: The Neurophysiology of Dopamine Systems, Chiodo, L.A. and A.S. Freeman (Eds.). Lake Shore Publications, Detroit, pp: 1-67.
  257. Grace, A.A., 1987. Commentary: An electrophysiologist's eye view of the basal ganglia. Behav. Brain Sci., 10: 197-245.
  258. Grace, A.A. and B.S. Bunney, 1986. Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: Analysis using in vivo intracellular recording. J. Pharmacol. Exp. Ther., 238: 1092-1100.
    Direct Link  |  
  259. Grace, A.A. and R. Llinas, 1985. Morphological artifacts induced in intracellularly stained neurons by dehydration: Circumvention using rapid dimethyl sulfoxide clearing. Neuroscience, 16: 461-475.
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  260. Grace, A.A. and R. Llinas, 1985. Dopamine. In: Neurotransmitter Actions in the Vertebrate Nervous System, Barker, J.L. and M.A. Rogawski (Eds.). Plenum Publishing Co., New York, pp: 285-319.
  261. Grace, A.A. and B.S. Bunney, 1985. Opposing effects of striatonigral feedback pathways on midbrain dopamine cell activity. Brain Res., 333: 271-284.
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  262. Grace, A.A. and B.S. Bunney, 1985. Low doses of apomorphine elicit two opposing influences on dopamine cell electrophysiology. Brain Res., 333: 285-298.
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  263. Bunney, B.S., L.A. Chiodo, A.A. Grace and J.O. Schenk, 1985. In vivo Effects of Acute and Chronic Antipsychotic Drug Administra¬tion on Midbrain Dopaminergic Neuron Activity. In: Behavioral Pharmacology: The Current Status, Balster, R. and L. Seiden (Eds.). Alan R. Liss Inc., New York, pp: 205-220.
  264. Grace, A.A. and B.S. Bunney, 1984. The control of firing pattern in nigral dopamine neurons: Single spike firing. J. Neurosci., 4: 2866-2876.
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  265. Grace, A.A. and B.S. Bunney, 1984. The control of firing pattern in nigral dopamine neurons: Burst firing. J. Neurosci., 4: 2877-2890.
    CrossRef  |  Direct Link  |  
  266. Grace, A.A. and B.S. Bunney, 1984. Striatal modulation of dopamine neuron firing. Clin. Neuropharmacol., 7: 64-65.
    Direct Link  |  
  267. Grace, A.A. and B.S. Bunney, 1984. Nigral Dopaminergic Neurons: Extracellular and Intracellular Electrophysiological Characteristics. In: Catecholamines: Neuropharmacology and Central Nervous System Theoretical Aspects, Usdin, E., A. Carlsson, A. Dahlstrom and J. Engel (Eds.). Alan R. Liss Inc., New York, pp: 323-332.
  268. Chiodo, L.A., M.J. Bannon, A.A. Grace, R.H. Roth and B.S. Bunney, 1984. Absence of autoreceptors on a subpopulation of mesocortical dopamine neurons: Electrophysiological and biochemical evidence. Neuroscience, 12: 1-16.
  269. Bunney, B.S., A.A. Grace and L.T. Meltzer, 1984. Midbrain dopaminergic neurons: A new model of their functioning? Clin. Neuropharmacol., 7: S49-S49.
    Direct Link  |  
  270. Bannon, M.J., L.A. Chiodo, E.B. Bunney, M.E. Wolf, A.A. Grace, B.S. Bunney and R.H. Roth, 1984. In vivo Biochemical and Electro¬physio¬logical Studies on the Distribution and Pharmacology of Dopamine Autoreceptors. In: Catecholamines: Neuropharmacology and Central Nervous System Theoretical Aspects, Usdin, E., A. Carlsson, A. Dahlstrom and J. Engel (Eds.). Alan R. Liss Inc., New York, pp: 25-36.
  271. Grace, A.A. and B.S. Bunney, 1983. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-3. Evidence for electrotonic coupling. Neuroscience, 10: 333-335, 337-348.
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  272. Grace, A.A. and B.S. Bunney, 1983. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-1. Identification and characterization. Neuroscience, 10: 301-305, 307-315.
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  273. Grace, A.A. and B.S. Bunney, 1983. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-2. Action potential generating mechanisms and morphological correlates. Neuroscience, 10: 317-319, 321-331.
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  274. Bunney, B.S., A.A. Grace, D.W. Hommer and L.R. Skirboll, 1982. Effect of Cholecystokinin on the Activity of Midbrain Dopaminergic Neurons. In: Advances in Biochemical Psychopharmacology, Volume 32, Costa, E. and M. Trabucci (Eds.). Raven Press, New York, pp: 429-437.
  275. Skirboll, L.R., T. Hokfelt, A.A. Grace, D.W. Hommer and J.F. Rehfeld et al., 1981. The Co Existence of Dopamine and a CCK Like Peptide in a Subpopulation of Midbrain Neurons: Immunocytochemical and Electrophysiological Studies. In: Apomorphine and other Dopaminomimetics, Volume 1: Basic Pharmacology, Gessa, G.L. and G.U. Corsini (Eds.). Raven Press, New York, pp: 65 77.
  276. Skirboll, L.R., A.A. Grace, D.W. Hommer, J. Rehfeld, M. Goldstein, T. Hokfelt and B.S. Bunney, 1981. Peptide-monoamine coexistence: Studies of the actions of cholecystokinin-like peptide on the electrical activity of midbrain dopamine neurons. Neuroscience, 6: 2111-2124.
    CrossRef  |  Direct Link  |  
  277. Grace, A.A., D.W. Hommer and B.S. Bunney, 1980. Peripheral and striatal influences on nigral dopamine cells: Mediation by reticulata neurons. Brain Res. Bull., 5: 105-109.
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  278. Grace, A.A. and B.S. Bunney, 1980. Nigral dopamine neurons: intracellular recording and identification with L-dopa injection and histofluorescence. Science, 210: 654-656.
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  279. Grace, A.A. and B.S. Bunney, 1980. Effects of baclofen on nigral dopaminergic cell activity following acute and chronic haloperidol treatment. Brain Res. Bull., 5: 537-543.
    CrossRef  |  Direct Link  |  
  280. Bunney, B.S., L.R. Skirboll and A.A. Grace, 1980. Acute and chronic haloperidol treatment: Effects on nigrostriatal dopaminergic system activity. Adv. Biochem. Psychopharmacol., 24: 267-273.
    PubMed  |  
  281. Bunney, B.S., A.A. Grace and D.W. Hommer, 1980. Changing concepts of nigral dopamine system function within the basal ganglia: Relevance to extrapyramidal disorders. J. Neural Trans., 16: 17-23.
  282. Bannon, M.J., A.A. Grace, B.S. Bunney and R.H. Roth, 1980. Evidence for an irreversible interaction of bromocryptine with central dopamine receptors. Naunyn Schmiedeberg's Arch. Pharmacol., 312: 37-41.
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  283. Skirboll, L.R., A.A. Grace and B.S. Bunney, 1979. Dopamine auto-and postsynaptic receptors: Electrophysiological evidence for differential sensitivity to dopamine agonists. Science, 206: 80-82.
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  284. Grace, A.A. and B.S. Bunney, 1979. Paradoxical GABA excitation of nigral dopaminergic cells: Indirect mediation through reticulata inhibitory neurons. Eur. J. Pharmacol., 59: 211-218.
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  285. Bunney, B.S. and A.A. Grace, 1979. Effects of Chronic Haloperidol Treatment on Nigral Dopaminergic Cell Activity. In: Catechola¬mines: Basic and Clinical Frontiers, Usdin, E., I.J. Kopin and J. Barchas (Eds.). Pergamon Press, New York, pp: 666-668.
  286. Bunney, B.S. and A.A. Grace, 1978. Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity. Life Sci., 23: 1715-1727.
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